Sommaire

• • ·Table of Contents

    Page :i

    
• • ·Editorial Board

    Page :iii

    
• • ·Information for Readers

    Page :iv

    

• Trial Designs

  • ·Rationale, design and prerandomization data for a cluster randomized trial to assess the effect of a digitally enabled quality improvement intervention on LDL-C control in established atherosclerotic cardiovascular disease patients: The SAPPHIRE-LDL trial

    Page :1-10

    M. Julia Machline-Carrion, Alysson Nathan Girotto, Priscila Raupp, Pedro Marton Pereira, Frederico Monfardini, Raul D. Santos, Karla Santo, Kausik Ray, Christopher P. Cannon, Otávio Berwanger

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  • ·Prospective randomized single-blind multicenter study to assess the safety and effectiveness of the SELUTION SLR 014 drug eluting balloon in the treatment of subjects with in-stent restenosis: Rationale and design

    Page :11-19

    Donald E. Cutlip, Roxana Mehran, Gheorghe Doros, Vladimir Kaplinskiy, Jane Lee, Luke Zheng, Milan Kausik, Eric Osborn, Ron Waksman

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  • ·Design, rationale, and characterization of the mobile health based occupational cardiovascular risk intervention study (mHealth-OPEN study)

    Page :32-41

    Yixin Tian, Xin Wang, Zhen Hu, Xue Yu, Min Shao, Chuanxi Zhang, Dedi Zhang, Wenping Shan, Chenye Chang, Chenda Zhang, Yuxuan Nie, Congyi Zheng, Xue Cao, Xuyan Pei, Yujie Zhang, Nuerguli Tuerdi, Zengwu Wang

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  • ·Rationale and design of the women's ischemia syndrome evaluation mechanisms of coronary microvascular dysfunction leading to preheart failure with preserved ejection fraction (WISE Pre-HFPEF)

    Page :47-56

    Tatsunori Takahashi, Janet Wei, Ana C. Iribarren, Martha Gulati, Galen Cook-Wiens, Michael D. Nelson, Behzad Sharif, Eileen M. Handberg, R. David Anderson, John Petersen, Daniel S. Berman, Carl J. Pepine, C. Noel Bairey Merz

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  • ·Functional coronary angiography to indicate and guide revascularization in STEMI patients with multivessel disease: Rationale and design of the AIR-STEMI trial

    Page :71-80

    Andrea Erriquez, Iginio Colaiori, Abdul Hakeem, Vincenzo Guiducci, Mila Menozzi, Marco Barbierato, Manfredi Arioti, Domenico D'Amario, Gianni Casella, Roberto Scarsini, Alberto Polimeni, Luca Donazzan, Giorgio Benatti, Gabriele Venturi, Marco Ruozzi, Massimo Giordan, Alberto Monello, Francesco Moretti, Francesco Versaci, Jehangir Ali Shah, Ahsan Ali Lakho, Francesca Mantovani, Caterina Cavazza, Giulia Bugani, Valerio Lanzilotti, Francesco Gallo, Antonio Maria Leone, Matteo Tebaldi, Rita Pavasini, Raffaele Piccolo, Filippo Maria Verardi, Jacopo Farina, Serena Caglioni, Marta Cocco, Gianluca Campo, Simone Biscaglia

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  • ·Occult cancer in patients with unprovoked venous thromboembolism: Rationale, design, and methods of the VaLRIETEs study and the SOME-RIETE trial

    Page :81-93

    Maria Barca-Hernando, Sonia Otalora-Valderrama, Juan Jose Lopez-Nuñez, Jose Portillo-Sanchez, Javier Pagan-Escribano, Patricia Lopez-Miguel, Isabelle Mahe, Elisabeth Mena-Muñoz, Ines Jou-Segovia, Egidio Imbalzano, Paloma Agudo-de Blas, Alicia Lorenzo-Hernandez, Carmen Diaz-Pedroche, Jesus Aibar-Gallizo, Gloria de la Red-Bellvis, Fatima del Molino-Sanz, Cristina Amado-Fernandez, Jose Luis Fernandez-Reyes, Aurora Villalobos-Sanchez, Juan Bosco Lopez-Saez, Ana Maria Diaz-Brasero, Maria Marcos-Jubilar, Jose Meireles, Pablo Javier Marchena-Yglesias, Jose Antonio Diaz-Peromingo, Samira Marin-Romero, Teresa Elias-Hernandez, Henry A Andrade-Ruiz, Ghazaleh Mehdipour, Behnood Bikdeli, Luis Jara-Palomares, The SOME-RIETE and ValRIETEs Investigators

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  • ·The left atrial appendage exclusion for prophylactic stroke reduction (LEAAPS) trial: Rationale and design

    Page :94-102

    Richard P. Whitlock, Patrick M. McCarthy, Marc W. Gerdisch, Basel Ramlawi, John H. Alexander, Ibrahim Sultan, David Z. Rose, Jeffrey S. Healey, Yashasvi Awasthi Sharma, Emilie P. Belley-Côté, Stuart J. Connolly

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• Clinical Investigations

  • ·Pharmaco-invasive strategy and dosing of tenecteplase in STEMI patients 60 to <75 years: An inter-trial comparison of the STREAM-1 and STREAM-2 trials

    Page :20-31

    Kevin R. Bainey, Robert C. Welsh, Yinggan Zheng, Alexandra Arias-Mendoza, Arsen D. Ristić, Oleg V. Averkov, Yves Lambert, Tracy Temple, Eric Ly, Kris Bogaerts, Peter Sinnaeve, Cynthia M. Westerhout, Frans Van de Werf, Paul W. Armstrong, STREAM-2 Investigators

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  • ·Impact of a clinical atrial fibrillation risk estimation tool on cardiac rhythm monitor utilization following acute ischemic stroke: A prepost clinical trial

    Page :57-66

    Jeffrey M. Ashburner, Reinier W.P. Tack, Shaan Khurshid, Ashby C. Turner, Steven J. Atlas, Daniel E. Singer, Patrick T. Ellinor, Emelia J. Benjamin, Ludovic Trinquart, Steven A. Lubitz, Christopher D. Anderson

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• Research Letters

  • ·Lipoprotein(a) immunoassays and their associations with coronary artery calcification and aortic valve calcification

    Page :42-46

    Maarten J.G. Leening, Ching F. Khan, Fang Zhu, Sunny S. Singh, Maryam Kavousi, Eric J.G. Sijbrands, Yolanda B. de Rijke, Daniel Bos

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  • ·Transcatheter or surgical aortic valve replacement in patients with severe aortic stenosis aged 70 years or younger: A NOTION-2 substudy

    Page :67-70

    Troels Højsgaard Jørgensen, Hans Gustav Hørsted Thyregod, Mikko Savontaus, Öjvind Bleie, Evald H Christiansen, Matti Niemela, Oskar Angerås, Ingibjörg J. Gudmundsdóttir, Mika Laine, Andreas Rück, Bernard Prendergast, Martin Leon, Lars Søndergaard, Ole De Backer, NOTION-2 investigators

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