Sommaire

• • ·Table of Contents

    Page :i

    
• • ·Editorial Board

    Page :iii

    
• • ·Information for Readers

    Page :iv

    

• Trial Designs

  • ·Ultra-low-dose quadruple combination blood pressure–lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol

    Page :56-67

    Clara K. Chow, Emily R. Atkins, Laurent Billot, John Chalmers, Graham S. Hillis, Peter Hay, Bruce Neal, Mark Nelson, Anushka Patel, Christopher M. Reid, Markus Schlaich, Tim Usherwood, Ruth Webster, Anthony Rodgers

    Résumé Résumé Plan Plan  
  • ·Randomized evaluation of beta blocker and ACE-inhibitor/angiotensin receptor blocker treatment in patients with myocardial infarction with non-obstructive coronary arteries (MINOCA-BAT): Rationale and design

    Page :96-104

    Anna M Nordenskjöld, Stefan Agewall, Dan Atar, Tomasz Baron, John Beltrame, Olle Bergström, David Erlinge, Chris P Gale, Javier López-Pais, Tomas Jernberg, Pelle Johansson, Annica Ravn-Fisher, Harmony R. Reynolds, Jithendra B. Somaratne, Per Tornvall, Bertil Lindahl

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  • ·Rationale and design of ApoA-I Event Reducing in Ischemic Syndromes II (AEGIS-II): A phase 3, multicenter, double-blind, randomized, placebo-controlled, parallel-group study to investigate the efficacy and safety of CSL112 in subjects after acute myocardial infarction

    Page :121-127

    C. Michael Gibson, John J.P. Kastelein, Adam T. Phillips, Philip E. Aylward, Megan K. Yee, Michal Tendera, Stephen J. Nicholls, Stuart Pocock, Shaun G. Goodman, John H. Alexander, A. Michael Lincoff, Christoph Bode, Danielle Duffy, Mark Heise, Gail Berman, Sojaita Jenny Mears, Pierluigi Tricoci, Lawrence I. Deckelbaum, P. Gabriel Steg, Paul Ridker, Roxana Mehran

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  • ·A randomized clinical trial to evaluate the efficacy and safety of rivaroxaban in patients with bioprosthetic mitral valve and atrial fibrillation or flutter: Rationale and design of the RIVER trial

    Page :128-136

    Helio P. Guimarães, Pedro G.M. de Barros e Silva, Idelzuita L. Liporace, Roney O. Sampaio, Flávio Tarasoutchi, Milena Paixão, Conrado R. Hoffmann-Filho, Rodrigo Patriota, Tiago L.L. Leiria, Diana Lamprea, Dalton B. Precoma, Fernando A. Atik, Fabio S. Silveira, Fabio R. Farias, Diogo O. Barreto, Adail P. Almeida, Alexandre C. Zilli, João D. de Souza Neto, Margaret A. Cavalcante, Fernando A.M.S. Figueira, Roque A. Junior, Valdir A. Moisés, Cezar E. Mesas, Roberto V. Ardito, Paulo S.A. Kalil, Maria S.M.O. Paiva, Jaime G.A. Maldonado, Carlos E.B. de Lima, Ricardo D'Oliveira Vieira, Ligia Laranjeira, Flávia Kojima, Lucas Damiani, Renato H. Nakagawa, Juliana R.Y. dos Santos, Bruna S. Sampaio, Viviane B. Campos, Jose F.K. Saraiva, Francisco H. Fonseca, Ibraim M. Pinto, Carlos C. Magalhães, Joao F.M. Ferreira, Renato D. Lopes, Ricardo Pavanello, Alexandre B. Cavalcanti, Otavio Berwanger, On behalf of the RIVER (RIvaroxaban for Valvular Heart diseasE and atRial Fibrillation Trial -RIVER Trial) Investigators

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  • ·The DANish randomized, double-blind, placebo controlled trial in patients with chronic HEART failure (DANHEART): A 2 × 2 factorial trial of hydralazine-isosorbide dinitrate in patients with chronic heart failure (H-HeFT) and metformin in patients with chronic heart failure and diabetes or prediabetes (Met-HeFT)

    Page :137-146

    Henrik Wiggers, Lars Køber, Gunnar Gislason, Morten Schou, Mikael Kjær Poulsen, Søren Vraa, Olav Wendelbo Nielsen, Niels Eske Bruun, Helene Nørrelund, Malene Hollingdal, Anders Barasa, Morten Bøttcher, Karen Dodt, Vibeke Brogaard Hansen, Gitte Nielsen, Anne Sejr Knudsen, Jens Lomholdt, Kirsten Vilain Mikkelsen, Bartlomiej Jonczy, Jens Brønnum-Schou, Monica Petronela Poenaru, Jawdat Abdulla, Ilan Raymond, Kiomars Mahboubi, Karen Sillesen, Kristine Serup-Hansen, Jette Sandberg Madsen, Søren Lund Kristensen, Anders Hostrup Larsen, Hans Erik Bøtker, Christian Torp-Petersen, Hans Eiskjær, Jacob Møller, Christian Hassager, Flemming Hald Steffensen, Bo Martin Bibby, Jens Refsgaard, Dan Eik Høfsten, Søren Mellemkjær, Finn Gustafsson

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  • ·Design and rationale of the XIENCE short DAPT clinical program: An assessment of the safety of 3-month and 1-month DAPT in patients at high bleeding risk undergoing PCI with an everolimus-eluting stent

    Page :147-156

    Marco Valgimigli, Davide Cao, Rajendra R. Makkar, Sripal Bangalore, Deepak L. Bhatt, Dominick J. Angiolillo, Shigeru Saito, Junbo Ge, Franz-Josef Neumann, James Hermiller, Hector Picon, Ralph Toelg, Aziz Maksoud, Bassem M. Chehab, Lijuan Jenny Wang, Jin Wang, Roxana Mehran

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• Clinical Investigations

  • ·Impact of the COVID-19 pandemic on patterns of outpatient cardiovascular care

    Page :1-5

    Jedrek Wosik, Megan E.B. Clowse, Robert Overton, Bhargav Adagarla, Nicoleta Economou-Zavlanos, Joanna Cavalier, Ricardo Henao, Jonathan P. Piccini, Laine Thomas, Michael J. Pencina, Neha J. Pagidipati

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  • ·Outpatient versus observation/inpatient management of emergency department patients rapidly ruled-out for acute myocardial infarction: Findings from the HIGH-US study

    Page :6-17

    Richard M. Nowak, Gordon Jacobsen, Alexander Limkakeng, William F. Peacock, Robert H. Christenson, James McCord, Fred S. Apple, Adam J Singer, Christopher R. deFilippi

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  • ·Association between levosimendan, postoperative AKI, and mortality in cardiac surgery: Insights from the LEVO-CTS trial

    Page :18-24

    Oliver K. Jawitz, Amanda S. Stebbins, Vignesh Raman, Brooke Alhanti, Sean van Diepen, Matthias Heringlake, Stephen Fremes, Richard Whitlock, Steven R. Meyer, Rajendra H. Mehta, Mark Stafford-Smith, Shaun G. Goodman, John H. Alexander, Renato D. Lopes

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  • ·National trends and 30-day readmission rates for next-day-discharge transcatheter aortic valve replacement: An analysis from the Nationwide Readmissions Database, 2012-2016

    Page :25-31

    Charan Yerasi, Byomesh Tripathi, Yanying Wang, Brian J. Forrestal, Brian C. Case, Jaffar M. Khan, Rebecca Torguson, Itsik Ben-Dor, Lowell F. Satler, Hector M. Garcia-Garcia, William S. Weintraub, Toby Rogers, Ron Waksman

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  • ·Statins and atherosclerotic cardiovascular outcomes in patients on incident dialysis and with atherosclerotic heart disease

    Page :36-44

    Jay S. Shavadia, Jonathan Wilson, Daniel Edmonston, Alyssa Platt, Patti Ephraim, Rasheeda Hall, Benjamin A. Goldstein, L. Ebony Boulware, Eric Peterson, Jane Pendergast, Julia J. Scialla

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  • ·Left bundle-branch block is associated with asimilar dyssynchronous phenotype in heart failure patients with normal and reduced ejection fractions

    Page :45-55

    Daniel J. Friedman, Kasper Emerek, Joseph Kisslo, Peter Søgaard, Brett D. Atwater

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  • ·Lipid temporal trends in normal-weight youth

    Page :68-72

    Justin P Zachariah, Teniola Shittu, Yunfei Wang

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  • ·Long-term outcomes of arrhythmia and distinct electrophysiological features in congenitally corrected transposition of the great arteries in an Asian cohort

    Page :73-81

    Wei-Chieh Tseng, Chi-Nan Huang, Shuenn-Nan Chiu, Chun-Wei Lu, Jou-Kou Wang, Ming-Tai Lin, Chun-An Chen, Mei-Hwan Wu

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  • ·The impact of left atrium size on selection of the pulmonary vein isolation method for atrial fibrillation: Cryoballoon or radiofrequency catheter ablation

    Page :82-92

    Takashi Ikenouchi, Osamu Inaba, Tomomasa Takamiya, Yukihiro Inamura, Akira Sato, Yutaka Matsumura, Hiroyuki Sato, Akihiro Hirakawa, Yoshihide Takahashi, Masahiko Goya, Tetsuo Sasano, Junichi Nitta

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  • ·Helicobacter pylori screening in clinical routine during hospitalization for acute myocardial infarction

    Page :105-109

    Jonatan Wärme, Martin Sundqvist, Katarina Mars, Layth Aladellie, Sven-Christian Pawelzik, David Erlinge, Tomas Jernberg, Stefan James, Robin Hofmann, Magnus Bäck

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  • ·Cost-effectiveness of combined catheter ablation and left atrial appendage closure for symptomatic atrial fibrillation in patients with high stroke and bleeding risk

    Page :110-120

    Hiroshi Kawakami, Mark T. Nolan, Karen Phillips, Paul A. Scuffham, Thomas H. Marwick

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• Research Letters

  • ·Association between intensive care unit utilization for patients with non–ST-segment elevation myocardial infarction and patient experience

    Page :32-35

    Alexander C. Fanaroff, Anita Y Chen, Sean van Diepen, Deirdre Mylod, Eric D Peterson, Tracy Y. Wang

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  • ·Thrombosis in hospitalized patients with viral respiratory infections versus COVID-19

    Page :93-95

    Nathaniel R. Smilowitz, Varun Subashchandran, Eugene Yuriditsky, James M. Horowitz, Harmony R. Reynolds, Judith S. Hochman, Jeffrey S. Berger

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  • ·Internet search volume for chest pain during the COVID-19 pandemic

    Page :157-159

    Jonathan L Ciofani, Daniel Han, Usaid K Allahwala, Kaleab N Asrress, Ravinay Bhindi

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• Letter to the Editors

  • ·Letter to the editor: Breaking the trend in cardiogenic shock—From door-to-balloon to door-to-support

    Page :160

    James Xu, Dominic Y. Leung, Sidney Lo

    
  • ·Reply to: Letter to the editor: Breaking the trend in cardiogenic shock—From door-to-balloon to door-to-support

    Page :161

    Marie D. Lauridsen, Jacob E. Møller, Lars Køber, Emil L. Fosbøl