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• • ·Table of Contents

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• • ·Editorial Board

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• • ·Information for Readers

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• Trial Designs

  • ·Evaluation of safety and efficacy of coronary intravascular lithotripsy for treatment of severely calcified coronary stenoses: Design and rationale for the Disrupt CAD III trial

    Page :10-18

    Dean J. Kereiakes, Jonathan M. Hill, Ori Ben-Yehuda, Akiko Maehara, Beaux Alexander, Gregg W. Stone

    Résumé Résumé Plan Plan   
  • ·TicagRelor Or Clopidogrel in severe or terminal chronic kidney patients Undergoing PERcutaneous coronary intervention for acute coronary syndrome: The TROUPER trial

    Page :19-26

    Marc Laine, Gilles Lemesle, Stéphane Burtey, Guillaume Cayla, Grégoire Range, Gonzalo Quaino, Matthias Canault, Mathieu Pankert, Franck Paganelli, Etienne Puymirat, Laurent Bonello

    Résumé Résumé Plan Plan  
  • ·Blunting periprocedural myocardial necrosis: Rationale and design of the randomized ALPHEUS study

    Page :27-37

    Johanne Silvain, Guillaume Cayla, Farzin Beygui, Grégoire Range, Benoit Lattuca, Jean-Philippe Collet, Jean-Guillaume Dillinger, Ziad Boueri, Philippe Brunel, Christophe Pouillot, Franck Boccara, Luc Christiaens, Jean-Noël Labeque, Thibault Lhermusier, Jean-Louis Georges, Anne Bellemain-Appaix, Hervé Le Breton, Marie Hauguel-Moreau, Christophe Saint-Etienne, Christophe Caussin, François Jourda, Zuzana Motovska, Paul Guedeney, Mohamad El Kasty, Mikael Laredo, Raphaëlle Dumaine, Grégory Ducrocq, Eric Vicaut, Gilles Montalescot, the ALPHEUS study group

    Résumé Résumé Plan Plan   
  • ·Randomized trial of argatroban plus recombinant tissue-type plasminogen activator for acute ischemic stroke (ARAIS): Rationale and design

    Page :38-43

    Yingying Yang, Zhonghe Zhou, Yuesong Pan, Huisheng Chen, Yilong Wang, ARAIS Protocol Steering Group

    Résumé Résumé Plan Plan  
  • ·Effect on thromboprophylaxis among hospitalized patients using a system-wide multifaceted quality improvement intervention: Rationale and design for a multicenter cluster randomized clinical trial in China

    Page :44-54

    Fen Dong, Kaiyuan Zhen, Zhu Zhang, Chaozeng Si, Jiefeng Xia, Tieshan Zhang, Lei Xia, Wei Wang, Cunbo Jia, Guangliang Shan, Zhenguo Zhai, Chen Wang, Chinese Prevention Strategy for Venous Thromboembolism (CHIPS-VTE) study group

    Résumé Résumé Plan Plan   
  • ·The INVICTUS rheumatic heart disease research program: Rationale, design and baseline characteristics of a randomized trial of rivaroxaban compared to vitamin K antagonists in rheumatic valvular disease and atrial fibrillation

    Page :69-77

    Ganesan Karthikeyan, Stuart J Connolly, Mpiko Ntsekhe, Alexander Benz, Sumathy Rangarajan, Gayle Lewis, Yan Yun, Sanjib Kumar Sharma, Fathi Maklady, Alaa Eldin Elghamrawy, Khawar Kazmi, Tantchou T J Cabral, Hu Dayi, Ma Changsheng, Bernard M Gitura, Alvaro Avezum, Liesl Zuhlke, Peter Lwabi, Abraham Haileamlak, Okechukwu Ogah, Pilly Chillo, Maria Paniagua, Ahmed ElSayed, Antonio Dans, Lillian Gondwe-Chunda, Onkabetse Julia Molefe-Baikai, Jesus A Gonzalez-Hermosillo, James Hakim, Albertino Damasceno, Emmanuel R Kamanzi, John Musuku, Kairat Davletov, Katherine Connolly, Bongani M Mayosi, Salim Yusuf, INVICTUS Investigators

    Résumé Résumé Plan Plan   

• Special Articles

  • ·A care pathway for the cardiovascular complications of COVID-19: Insights from an institutional response

    Page :3-9

    Rahul S. Loungani, Michael R. Rehorn, L. Kristin Newby, Jason N. Katz, Igor Klem, Robert J. Mentz, W. Schuyler Jones, Sreekanth Vemulapalli, Anita M. Kelsey, Michael A. Blazing, Jonathan P. Piccini, Manesh R. Patel

    Résumé Résumé Plan Plan  

• Clinical Investigations

  • ·Radial versus femoral artery access for percutaneous coronary artery intervention in patients with acute myocardial infarction and multivessel disease complicated by cardiogenic shock: Subanalysis from the CULPRIT-SHOCK trial

    Page :60-68

    Paul Guedeney, Holger Thiele, Mathieu Kerneis, Olivier Barthélémy, Stefan Baumann, Marcus Sandri, Suzanne de Waha-Thiele, Georg Fuernau, Stéphanie Rouanet, Jan J. Piek, Ulf Landmesser, Marie Hauguel-Moreau, Michel Zeitouni, Johanne Silvain, Benoit Lattuca, Stephan Windecker, Jean-Philippe Collet, Steffen Desch, Uwe Zeymer, Gilles Montalescot, Ibrahim Akin, CULPRIT-SHOCK Investigators

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  • ·Epinephrine stress testing during cardiac catheterization in patients with aortic coarctation

    Page :78-87

    Timion A. Meijs, Gregor J. Krings, Anan Saad, Mirella M.C. Molenschot, Pieter A. Doevendans, Michiel Voskuil

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  • ·Beliefs, risk perceptions, and lipid management among patients with and without diabetes: Results from the PALM registry

    Page :88-96

    Angela Lowenstern, Shuang Li, Salim S. Virani, Ann Marie Navar, Zhuokai Li, Jennifer G. Robinson, Veronique L. Roger, Anne C. Goldberg, Andrew Koren, Michael J. Louie, Eric D. Peterson, Tracy Y. Wang

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  • ·In patients with stable coronary heart disease, low-density lipoprotein-cholesterol levels < 70 mg/dL and glycosylated hemoglobin A1c <?7% are associated with lower major cardiovascular events

    Page :97-107

    Harvey D. White, Ralph A.H. Stewart, Anthony J. Dalby, Amanda Stebbins, Christopher P. Cannon, Andrzej Budaj, Ales Linhart, Prem Pais, Rafael Diaz, Philippe Gabriel Steg, Sue Krug-Gourley, Christopher B. Granger, Judith S. Hochman, Wolfgang Koenig, Robert A. Harrington, Claes Held, Lars Wallentin, on behalf of the STABILITY Investigators

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  • ·Expanding the clinical and genetic spectrum of ALPK3 variants: Phenotypes identified in pediatric cardiomyopathy patients and adults with heterozygous variants

    Page :108-119

    Johanna C. Herkert, Judith M.A. Verhagen, Raquel Yotti, Alireza Haghighi, Dean G. Phelan, Paul A. James, Natasha J. Brown, Chloe Stutterd, Ivan Macciocca, Kai'En Leong, Marian L.C. Bulthuis, Yolande van Bever, Marjon A. van Slegtenhorst, Ludolf G. Boven, Amy E. Roberts, Radhika Agarwal, Jonathan Seidman, Neal K. Lakdawala, Francisco Fernández-Avilés, Michael A. Burke, Mary Ella. Pierpont, Elizabeth Braunlin, Ahmet Okay ?a?layan, Daniela Q.C.M. Barge-Schaapveld, Erwin Birnie, Lennie van Osch-Gevers, Irene M. van Langen, Jan D.H. Jongbloed, Paul J. Lockhart, David J. Amor, Christine E. Seidman, Ingrid M.B.H. van de Laar

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  • ·Outcomes in Kawasaki disease patients with coronary artery abnormalities at admission

    Page :120-128

    Ryusuke Ae, Joseph Y. Abrams, Ryan A. Maddox, Lawrence B. Schonberger, Yosikazu Nakamura, Masanari Kuwabara, Nobuko Makino, Yuri Matsubara, Daisuke Matsubara, Koki Kosami, Teppei Sasahara, Ermias D. Belay

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  • ·Targeted temperature management in cardiac arrest patients with a non-shockable rhythm: A national perspective

    Page :129-137

    Muhammad Zia Khan, Samian Sulaiman, Pratik Agrawal, Mohammed Osman, Muhammad U. Khan, Safi U. Khan, Sudarshan Balla, Muhammad Bilal Munir

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  • ·TAVR for low-flow, low-gradient aortic stenosis: Prognostic impact of aortic valve calcification

    Page :138-148

    Sebastian Ludwig, Alina Goßling, Lara Waldschmidt, Matthias Linder, Oliver D. Bhadra, Lisa Voigtländer, Andreas Schäfer, Florian Deuschl, Johannes Schirmer, Hermann Reichenspurner, Stefan Blankenberg, Ulrich Schäfer, Dirk Westermann, Moritz Seiffert, Lenard Conradi, Niklas Schofer

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• Research Letters

  • ·Coronary revascularization and circulatory support strategies in patients with myocardial infarction, multi-vessel coronary artery disease, and cardiogenic shock: Insights from an international survey

    Page :55-59

    Nathaniel R. Smilowitz, Aubrey C. Galloway, E. Magnus Ohman, Sunil V. Rao, Sripal Bangalore, Stuart D. Katz, Judith S. Hochman

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• Letter to the Editors

  • ·COVID-19 pandemic—Some cardiovascular considerations from the trench

    Page :1-2

    Bernardo Cortese

    Plan Plan