Sommaire

• • ·Table of Contents

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• • ·Editorial Board

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• • ·Information for Readers

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• Curriculum in Cardiology

  • ·Impact of rejection-related immune responses on the initiation and progression of cardiac allograft vasculopathy

    Page :46-63

    Michael Dandel, Roland Hetzer

    Résumé Résumé Plan Plan  
  • ·Paclitaxel-related balloons and stents for the treatment of peripheral artery disease: Insights from the Food and Drug Administration 2019 Circulatory System Devices Panel Meeting on late mortality

    Page :112-120

    Kazuhiro Dan, Evan Shlofmitz, Nauman Khalid, Alexandre Hideo-Kajita, Jason P. Wermers, Rebecca Torguson, Paul Kolm, Hector M. Garcia-Garcia, Ron Waksman

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• Trial Designs

  • ·Rationale and design of the Flow Evaluation to Guide Revascularization in Multivessel ST-Elevation Myocardial Infarction (FLOWER-MI) trial

    Page :1-7

    Etienne Puymirat, Tabassome Simon, Bernard de Bruyne, Gilles Montalescot, Gabriel Steg, Guillaume Cayla, Isabelle Durand-Zaleski, Didier Blanchard, Nicolas Danchin, Gilles Chatellier, FLOWER-MI study investigators

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  • ·Cryoballoon catheter ablation versus antiarrhythmic drugs as a first-line therapy for patients with paroxysmal atrial fibrillation: Rationale and design of the international Cryo-FIRST study

    Page :64-72

    Jean Sylvain Hermida, Jian Chen, Christian Meyer, Saverio Iacopino, Giuseppe Arena, Nikola Pavlovic, Vedran Velagic, Stewart Healey, Douglas L. Packer, Heinz-Friedrich Pitschner, Carlo de Asmundis, Malte Kuniss, Gian Battista Chierchia

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  • ·Implementation of Best Practices—Developing and Optimizing Regional Systems of Stroke Care: Design and Methodology

    Page :105-111

    Matthew E Ehrlich, Brad J. Kolls, Mayme Roettig, Lisa Monk, Shreyansh Shah, Ying Xian, James G. Jollis, Christopher B. Granger, Carmelo Graffagnino

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  • ·EMERGEncy versus delayed coronary angiogram in survivors of out-of-hospital cardiac arrest with no obvious non-cardiac cause of arrest: Design of the EMERGE trial

    Page :131-138

    Caroline Hauw-Berlemont, Lionel Lamhaut, Jean-Luc Diehl, Christophe Andreotti, Olivier Varenne, Pierre Leroux, Jean-Baptiste Lascarrou, Patrice Guerin, Thomas Loeb, Eric Roupie, Cédric Daubin, Farzin Beygui, Aurélie Vilfaillot, Sophie Glippa, Juliette Djadi-Prat, Gilles Chatellier, Alain Cariou, Christian Spaulding, for the EMERGE investigators

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  • ·Distal Evaluation of Functional performance with Intravascular sensors to assess the Narrowing Effect—combined pressure and Doppler FLOW velocity measurements (DEFINE-FLOW) trial: Rationale and trial design

    Page :139-146

    Valérie E. Stegehuis, Gilbert W.M. Wijntjens, Tim P. van de Hoef, Lorena Casadonte, Richard L. Kirkeeide, Maria Siebes, Jos A.E. Spaan, K. Lance Gould, Nils P. Johnson, Jan J. Piek

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  • ·Outcome impact of different tranexamic acid regimens in cardiac surgery with cardiopulmonary bypass (OPTIMAL): Rationale, design, and study protocol of a multicenter randomized controlled trial

    Page :147-156

    Jia Shi, Chenghui Zhou, Sheng Liu, Hansong Sun, Yang Wang, Fuxia Yan, Wei Pan, Zhe Zheng

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  • ·Study design of Dal-GenE, a pharmacogenetic trial targeting reduction of cardiovascular events with dalcetrapib

    Page :157-165

    Jean-Claude Tardif, Marie-Pierre Dubé, Marc A. Pfeffer, David D. Waters, Wolfgang Koenig, Aldo P. Maggioni, John J.V. McMurray, Vincent Mooser, Harvey D. White, Therese Heinonen, Donald M. Black, Marie-Claude Guertin, for the dal-GenE Investigators

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  • ·Xarelto plus Acetylsalicylic acid: Treatment patterns and Outcomes in patients with Atherosclerosis (XATOA): Rationale and design of a prospective registry study to assess rivaroxaban 2.5 mg twice daily plus aspirin for prevention of atherothrombotic events in coronary artery disease, peripheral artery disease, or both

    Page :166-173

    Keith A.A. Fox, Sonia S. Anand, Victor Aboyans, Martin R. Cowie, E. Sebastian Debus, Uwe Zeymer, Danja Monje, Kai Vogtländer, Robert Lawatscheck, Alain Gay

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  • ·Second-Generation Drug-Eluting Stents in Diabetes (SUGAR) trial: Rationale and study design

    Page :174-182

    Rafael Romaguera, Pablo Salinas, Salvatore Brugaletta, Josep Gomez-Lara, José F. Díaz, Miguel A. Romero, Sergio García-Blas, Raymundo Ocaranza, Pascual Borde, Marcelo Jiménez Kockar, Raul Millan Segovia, Andrés Íñiguez, Mar Alameda, Ramiro Trillo, Dae Hyun Lee, Pedro Martín, María López-Benito, Araceli Frutos, José Moreu, Felipe Hernández-Hernández, Bruno García del Blanco, Gerard Roura, Xavier Rossello, Stuart J. Pocock, Antonio Fernández-Ortiz, Manel Sabate, JA Gómez-Hospital

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  • ·Rationale and design for a multicenter, randomized, double-blind, placebo-controlled, phase 2 study evaluating the safety and efficacy of the soluble guanylate cyclase stimulator praliciguat over 12 weeks in patients with heart failure with preserved ejection fraction (CAPACITY HFpEF)

    Page :183-190

    James E. Udelson, Gregory D. Lewis, Sanjiv J. Shah, Michael R. Zile, Margaret M. Redfield, John Burnett, Robert S. Mittleman, Albert T. Profy, Jelena P. Seferovic, David Reasner, Marvin A. Konstam

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• Clinical Investigations

  • ·Incidence, underlying conditions, and outcomes of patients receiving acute renal replacement therapies in tertiary cardiac intensive care units: An analysis from the Critical Care Cardiology Trials Network Registry

    Page :8-14

    Sean van Diepen, Wayne Tymchak, Erin A. Bohula, Jeong-Gun Park, Lori B. Daniels, Nicholas Phreaner, Christopher F. Barnett, Benjamin B Kenigsberg, Andrew DeFilippis, Narayana Sarma Singam, Gregory W. Barsness, Jacob C. Jentzer, Bradley Ternus, David A. Morrow, Jason N. Katz, Critical Care Cardiology Trials Network Investigators

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  • ·Complex high-risk and indicated percutaneous coronary intervention for stable angina: Does operator volume influence patient outcome?

    Page :15-25

    Tim Kinnaird, Sean Gallagher, James C. Spratt, Peter Ludman, Mark de Belder, Samuel Copt, Richard Anderson, Simon Walsh, Colm Hanratty, Nick Curzen, Adrian Banning, Mamas Mamas

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  • ·Long-term clinical outcomes with use of an angiotensin-converting enzyme inhibitor early after heart transplantation

    Page :30-37

    Hiroyuki Arashi, Takuma Sato, Jon Kobashigawa, Helen Luikart, Yuhei Kobayashi, Kozo Okada, Seema Sinha, Yasuhiro Honda, Alan C. Yeung, Kiran Khush, William F. Fearon

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  • ·Contraceptive methods of privately insured US women with congenital heart defects

    Page :38-45

    Kayla N. Anderson, Naomi K. Tepper, Karrie Downing, Elizabeth C. Ailes, Ginnie Abarbanell, Sherry L. Farr

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  • ·Underweight is associated with inferior short and long-term outcomes after MitraClip implantation: Results from the German TRAnscatheter mitral valve interventions (TRAMI) registry

    Page :73-82

    Daniel Kalbacher, Eike Tigges, Peter Boekstegers, Miriam Puls, Björn Plicht, Holger Eggebrecht, Georg Nickenig, Ralph Stephan von Bardeleben, Christine Stephanie Zuern, Jennifer Franke, Horst Sievert, Taoufik Ouarrak, Jochen Senges, Edith Lubos

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  • ·Treatment strategies and subsequent changes in the patient-reported quality-of-life among elderly patients with atrial fibrillation

    Page :83-92

    Kotaro Miura, Nobuhiro Ikemura, Takehiro Kimura, Yoshinori Katsumata, Ikuko Ueda, Kojiro Tanimoto, Takahiro Ohki, Daisuke Shinmura, Koji Negishi, Keiichi Fukuda, Seiji Takatsuki, Shun Kohsaka

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  • ·Modeling defibrillation benefit for survival among cardiac resynchronization therapy defibrillator recipients

    Page :93-104

    Kenneth C. Bilchick, Yongfei Wang, Jeptha P. Curtis, Alan Cheng, Kumar Dharmarajan, Ramin Shadman, Todd F Dardas, Inder Anand, Lars H. Lund, Ulf Dahlström, Ulrik Sartipy, Aldo Maggioni, Christopher O'Connor, Wayne C. Levy

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  • ·Comparison between ticagrelor and clopidogrel on myocardial blood flow in patients with acute coronary syndrome, using 13 N-ammonia positron emission tomography

    Page :121-130

    Young Jin Jeong, Kyungil Park, Young-Dae Kim

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  • ·Emergency department evaluation of chest pain among adult congenital heart disease patients

    Page :191-198

    Jordan Gales, Richard A. Krasuski, Jordan D. Awerbach

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  • ·Aldosterone-to-renin ratio and blood pressure in young adults from the general population

    Page :199-207

    Stefanie Aeschbacher, Michel Mongiat, Raffaele Bernasconi, Steffen Blum, Pascal Meyre, Philipp Krisai, Selinda Ceylan, Martin Risch, Lorenz Risch, David Conen

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  • ·Sedentary time and peripheral artery disease: The Hispanic Community Health Study/Study of Latinos

    Page :208-219

    Jonathan T. Unkart, Matthew A. Allison, Humberto Parada, Michael H. Criqui, Qibin Qi, Keith M. Diaz, Jordan A. Carlson, Daniela Sotres-Alvarez, Robert J. Ostfeld, Leopoldo Raij, John Bellettiere

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  • ·Association of postoperative complications and outcomes following coronary artery bypass grafting

    Page :220-228

    Oliver K. Jawitz, Brian C. Gulack, J. Matthew Brennan, Dylan P. Thibault, Alice Wang, Sean M. O'Brien, Jacob N. Schroder, Jeffrey G. Gaca, Peter K. Smith

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• Research Letters

  • ·Outcomes following cardioversion for patients with cardiac amyloidosis and atrial fibrillation or atrial flutter

    Page :26-29

    Rahul S Loungani, Michael R. Rehorn, Kyle R. Geurink, Amanda C. Coniglio, Eric Black-Maier, Sean D. Pokorney, Michel G. Khouri

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