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• • ·Table of Contents

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• • ·Editorial Board

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• • ·Information for Readers

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• Editorials

  • ·Angiotensin receptor-neprilysin inhibitor therapy in heart failure: An end that justifies the means

    Page :176-177

    Andrew P. Ambrosy, Eric J. Velazquez

    
  • ·IABP and cardiogenic shock: A heartbreaking story

    Page :178-180

    Karim Bendjelid

    

• Curriculum in Cardiology

  • ·The prognostic value of heart rate recovery in patients with coronary artery disease: A systematic review and meta-analysis

    Page :163-169

    Sangeeta Lachman, Michel S. Terbraak, Jacqueline Limpens, Harald Jorstad, Cees Lucas, Wilma Scholte op Reimer, S. Matthijs Boekholdt, Gerben ter Riet, Ron J.G. Peters

    Résumé Résumé Plan Plan   

• Cardiac Safety Research Consortium

  • ·Is there a role for pharmacokinetic/pharmacodynamic-guided dosing for novel oral anticoagulants?

    Page :59-67

    Noel Chan, Philip T. Sager, Jack Lawrence, Thomas's Ortel, Paul Reilly, Scott Berkowitz, Dagmar Kubitza, John Eikelboom, Jeffry Florian, Norman Stockbridge, Martin Rose, Robert Temple, Jonathan H. Seltzer

    Résumé Résumé Plan Plan  

• Trial Designs

  • ·Comparison of Fractional FLow Reserve And Intravascular ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with InteRmediate Stenosis (FLAVOUR): Rationale and design of a randomized clinical trial

    Page :7-12

    Jeehoon Kang, Bon-Kwon Koo, Xinyang Hu, Joo Myung Lee, Joo-Yong Hahn, Hyoung-Mo Yang, Eun-Seok Shin, Chang-Wook Nam, Joon-Hyung Doh, Bong-Ki Lee, Chul Ahn, JianAn Wang, Seung-Jae Tahk

    Résumé Résumé Plan Plan  
  • ·Rationale and design of a trial to personalize risk assessment in familial coronary artery disease

    Page :22-30

    Thomas H Marwick, Kristyn Whitmore, Stephen J Nicholls, Tony Stanton, Geoffrey Mitchell, Andrew Tonkin, Christopher Blizzard, Amanda Neil, Catherine Jones, Gerald F Watts, CAUGHT-CAD Investigators

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  • ·A otype-directed comparative ffectiveness ral of Buindolol and metoprolol succinate for prevention of symptomatic trial ibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial

    Page :51-58

    Jonathan P. Piccini, Stuart J. Connolly, William T. Abraham, Jeff S. Healey, Benjamin A. Steinberg, Hussein R. Al-Khalidi, Patricia Dignacco, Dirk J. van Veldhuisen, William H. Sauer, Michel White, Stephen B. Wilton, Inder S. Anand, Christopher Dufton, Debra A. Marshall, Ryan G. Aleong, Gordon W. Davis, Richard L. Clark, Laura L. Emery, Michael R. Bristow

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  • ·Knowledge to action: Rationale and design of the Patient-Centered Care Transitions in Heart Failure (PACT-HF) stepped wedge cluster randomized trial

    Page :75-82

    Harriette G.C. Van Spall, Shun Fu Lee, Feng Xie, Dennis T. Ko, Lehana Thabane, Quazi Ibrahim, Peter R. Mitoff, Michael Heffernan, Manish Maingi, Michael C. Tjandrawidjaja, Mohammad I. Zia, Mohamed Panju, Richard Perez, Kim D. Simek, Liane Porepa, Ian D. Graham, R. Brian Haynes, Dilys Haughton, Stuart J. Connolly

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  • ·Rationale and design for the Vascular Outcomes study of ASA along with rivaroxaban in endovascular or surgical limb revascularization for peripheral artery disease (VOYAGER PAD)

    Page :83-91

    Warren H. Capell, Marc P. Bonaca, Mark R. Nehler, Edmond Chen, John M. Kittelson, Sonia S. Anand, Scott D. Berkowitz, Eike Sebastian Debus, Fabrizio Fanelli, Lloyd Haskell, Manesh R. Patel, Rupert Bauersachs, William R. Hiatt

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  • ·The cVAD registry for percutaneous temporary hemodynamic support: A prospective registry of Impella mechanical circulatory support use in high-risk PCI, cardiogenic shock, and decompensated heart failure

    Page :115-121

    George W. Vetrovec, Mark Anderson, Theodore Schreiber, Jeffrey Popma, William Lombardi, Brijeshwar Maini, Jacob Eifer Moller, Andreas Schäfer, Simon R. Dixon, Shelley Hall, E. Magnus Ohman, Catalin Mindrescu, Jeffrey Moses, William O'Neill

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  • ·Rationale and methods of the Prospective Study of Biomarkers, Symptom Improvement, and Ventricular Remodeling During Sacubitril/Valsartan Therapy for Heart Failure (PROVE-HF)

    Page :130-136

    James L. Januzzi, Javed Butler, Emmanuel Fombu, Alan Maisel, Kevin McCague, Ileana L. Piña, Margaret F. Prescott, Jerome B. Riebman, Scott Solomon

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  • ·Catheter Ablation versus Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) Trial: Study Rationale and Design

    Page :192-199

    Douglas L. Packer, Daniel B. Mark, Richard A Robb, Kristi H. Monahan, Tristram D. Bahnson, Kathleen Moretz, Jeanne E. Poole, Alice Mascette, Yves Rosenberg, Neal Jeffries, Hussein R. Al-Khalidi, Kerry L. Lee, CABANA Investigators

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• Clinical Investigations

  • ·Effect of carvedilol vs metoprolol succinate on mortality in heart failure with reduced ejection fraction

    Page :1-6

    Tarek Ajam, Samer Ajam, Srikant Devaraj, Kahee Mohammed, Stephen Sawada, Masoor Kamalesh

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  • ·Shared decision-making tool for thromboprophylaxis in atrial fibrillation – A feasibility study

    Page :13-21

    Mark H. Eckman, Alexandru Costea, Mehran Attari, Jitender Munjal, Ruth E. Wise, Carol Knochelmann, Matthew L. Flaherty, Pete Baker, Robert Ireton, Brett M. Harnett, Anthony C. Leonard, Dylan Steen, Adam Rose, John Kues

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  • ·The prognostic value of the relationship between right atrial and pulmonary capillary wedge pressure in diverse cardiovascular conditions

    Page :31-36

    Douglas Marshall Brinkley, Kalon K.L. Ho, Mark H. Drazner, Robb D. Kociol

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  • ·Investigation of Motivational Interviewing and Prevention Consults to Achieve Cardiovascular Targets (IMPACT) trial

    Page :37-43

    Eugenia Gianos, Antoinette Schoenthaler, Yu Guo, Judy Zhong, Howard Weintraub, Arthur Schwartzbard, James Underberg, Michael Schloss, Jonathan D. Newman, Sean Heffron, Edward A. Fisher, Jeffrey S. Berger

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  • ·Transcatheter closure of patent foramen ovale following cryptogenic stroke: An updated meta-analysis of randomized controlled trials

    Page :44-50

    Haris Riaz, Muhammad Shahzeb Khan, Aldo L. Schenone, Anam A. Waheed, Arooj Razzak Khan, Richard A. Krasuski

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  • ·Resource utilization and outcome among patients with selective versus nonselective troponin testing

    Page :68-74

    Alex R. Campbell, Alexander J. Rodriguez, David M. Larson, Craig E. Strauss, Ross F. Garberich, Matthew F. Partridge, Timothy D. Henry, Scott W. Sharkey

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  • ·Trends and outcomes of cardiac transplantation from donors dying of drug intoxication

    Page :92-96

    Haider J. Warraich, Di Lu, Stacy Cobb, Lauren B. Cooper, Adam DeVore, Chetan B. Patel, Paul B. Rosenberg, Jacob N. Schroder, Mani A. Daneshmand, Carmelo A. Milano, Adrian F. Hernandez, Joseph G. Rogers, Robert J. Mentz

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  • ·Prevalent digoxin use and subsequent risk of death or hospitalization in ambulatory heart failure patients with a reduced ejection fraction—Findings from the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) randomized controlled trial

    Page :97-104

    Andrew P. Ambrosy, Ankeet S. Bhatt, Amanda L. Stebbins, Lisa M. Wruck, Marat Fudim, Stephen J. Greene, William E. Kraus, Christopher M. O'Connor, Ileana L. Piña, David J. Whellan, Robert J. Mentz

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  • ·Effects of a 12-week mHealth program on peak VO₂ and physical activity patterns after completing cardiac rehabilitation: A randomized controlled trial

    Page :105-114

    Brian D. Duscha, Lucy W. Piner, Mahesh P. Patel, Karen P. Craig, Morgan Brady, Robert W. McGarrah, Connie Chen, William E. Kraus

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  • ·Telemedicine cardiovascular risk reduction in veterans: The CITIES trial

    Page :122-129

    Hayden B. Bosworth, Maren K. Olsen, Felicia McCant, Karen M. Stechuchak, Susanne Danus, Matthew J. Crowley, Karen M. Goldstein, Leah L. Zullig, Eugene Z. Oddone

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  • ·Risk of cardiovascular events and incident atrial fibrillation in patients without prior atrial fibrillation: Implications for expanding the indications for anticoagulation

    Page :137-143

    Xiaoxi Yao, Bernard J. Gersh, Lindsey R. Sangaralingham, Nilay D. Shah, Peter A. Noseworthy

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  • ·Trends in the incidence and outcomes of patients with aortic stenosis hospitalization

    Page :144-149

    Andrew Czarnecki, Feng Qiu, Maria Koh, David A. Alter, Peter C. Austin, Stephen E. Fremes, Jack V. Tu, Harindra C. Wijeysundera, Andrew T. Yan, Dennis T. Ko

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  • ·Dual antiplatelet therapy for perioperative myocardial infarction following CABG surgery

    Page :150-155

    Alice Wang, Angie Wu, Daniel Wojdyla, Renato D. Lopes, L. Kristin Newby, Mark F. Newman, Peter K. Smith, John H. Alexander

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  • ·Characteristics and long term outcomes of patients with acute coronary syndromes due to culprit left main coronary artery disease treated with percutaneous coronary intervention

    Page :156-162

    S. Michael Gharacholou, Nkechinyere N. Ijioma, Ryan J. Lennon, Charanjit S. Rihal, Malcolm R. Bell, Jorge A. Brenes-Salazar, Gurpreet S. Sandhu, Rajiv Gulati, Patricia A. Pellikka, Peter M. Pollak, Gary E. Lane, Dilip P. Pillai, Freddy Del-Carpio Munoz, Arashk Motiei, Mandeep Singh

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  • ·Predictors of intra-aortic balloon pump hemodynamic failure in non-acute myocardial infarction cardiogenic shock

    Page :181-191

    Steven Hsu, Swetha Kambhampati Thiruvengadam, Christopher M. Sciortino, Stuart D. Russell, Steven P. Schulman

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• Research Letter

  • ·Baseline characteristics and temporal differences in Acarbose Cardiovascular Evaluation (ACE) trial participants

    Page :170-175

    Michael J. Theodorakis, Ruth L. Coleman, Huimei Feng, Juliana Chan, Jean-Louis Chiasson, Junbo Ge, Hertzel C. Gerstein, Yong Huo, Zhihui Lang, John J. McMurray, Lars Rydén, Stefan Schröder, Michal Tendera, Jaakko Tuomilehto, Wenying Yang, Dayi Hu, Changyu Pan, Rury R. Holman, ACE Study Group

    Plan Plan