Sommaire

• • ·Contents

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• • ·Editorial Board

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• • ·Information for Readers

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• Editorials

  • ·Improving outcomes in primary percutaneous coronary intervention: Transradial is worth the time

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    Samir B. Pancholy, Sunil V. Rao

     
  • ·Trial to Assess Chelation Therapy (TACT) and equipoise: When evidence conflicts with beliefs

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    David J. Maron, Mark A. Hlatky

    Plan Plan

• Curriculum in Cardiology

  • ·A systematic review of statin-induced muscle problems in clinical trials

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    Harsha V. Ganga, Hanna B. Slim, Paul D. Thompson

    Résumé Résumé Plan Plan  

• Trial Design

  • ·CYP2C19 genotype–guided antiplatelet therapy in ST-segment elevation myocardial infarction patients—Rationale and design of the Patient Outcome after primary PCI (POPular) Genetics study

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    Thomas O. Bergmeijer, Paul W.A. Janssen, Jurjan C. Schipper, Khalid Qaderdan, Maycel Ishak, Rianne S. Ruitenbeek, Folkert W. Asselbergs, Arnoud W.J. van ‘t Hof, Willem J.M. Dewilde, Fabrizio Spanó, Jean-Paul R. Herrman, Johannes C. Kelder, Maarten J. Postma, Anthonius de Boer, Vera H.M. Deneer, Jurriën M. ten Berg

    Résumé Résumé Plan Plan  
  • ·Rationale for and design of the Acarbose Cardiovascular Evaluation (ACE) trial

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    Rury R. Holman, Mary A. Bethel, Juliana C.N. Chan, Jean-Louis Chiasson, Zoë Doran, Junbo Ge, Hertzel Gerstein, Yong Huo, John J. McMurray, Lars Ryden, Winitha Liyanage, Stefan Schröder, Michal Tendera, Michael J. Theodorakis, Jaakko Tuomilehto, Wenying Yang, Dayi Hu, Changyu Pan, ACE Study Group

    Résumé Résumé Plan Plan  
  • ·Rationale and design of PRIMA II: A multicenter, randomized clinical trial to study the impact of in-hospital guidance for acute decompensated heart failure treatment by a predefined NT-PRoBNP target on the reduction of readmIssion and Mortality rAtes

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    Susan Stienen, Khibar Salah, Andreas H.M. Moons, Adrianus L.M. Bakx, Petra E. van Pol, Jutta M. Schroeder-Tanka, Albertus J. Voogel, Jan T. Keijer, R.A. Mikael Kortz, Cathelijne Dickhoff, Paola G. Meregalli, Jan G. Tijssen, Yigal M. Pinto, Wouter E. Kok

    Résumé Résumé Plan Plan  

• Clinical Investigations

  • ·EDTA chelation therapy alone and in combination with oral high-dose multivitamins and minerals for coronary disease: The factorial group results of the Trial to Assess Chelation Therapy

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    Gervasio A. Lamas, Robin Boineau, Christine Goertz, Daniel B. Mark, Yves Rosenberg, Mario Stylianou, Theodore Rozema, Richard L. Nahin, L. Terry Chappell, Lauren Lindblad, Eldrin F. Lewis, Jeanne Drisko, Kerry L. Lee

    Résumé Résumé Plan Plan  
  • ·A metabolomic profile is associated with the risk of incident coronary heart disease

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    Anika A.M. Vaarhorst, Aswin Verhoeven, Claudia M. Weller, Stefan Böhringer, Sibel Göraler, Axel Meissner, André M. Deelder, Peter Henneman, Anton P.M. Gorgels, Piet A. van den Brandt, Leo J. Schouten, Marleen M. van Greevenbroek, Audrey H.H. Merry, W.M. Monique Verschuren, Arn M.J.M. van den Maagdenberg, Ko Willems van Dijk, Aaron Isaacs, Dorret Boomsma, Ben A. Oostra, Cornelia M. van Duijn, J. Wouter Jukema, Jolanda M.A. Boer, Edith Feskens, Bastiaan T. Heijmans, P. Eline Slagboom

    Résumé Résumé Plan Plan  
  • ·Trends in the pharmacologic management of atrial fibrillation: Data from the Veterans Affairs health system

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    Mary S. Vaughan-Sarrazin, Alexander Mazur, Elizabeth Chrischilles, Peter Cram

    Résumé Résumé Plan Plan  
  • ·Which risk score best predicts perioperative outcomes in nonvalvular atrial fibrillation patients undergoing noncardiac surgery?

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    Sean van Diepen, Erik Youngson, Justin A. Ezekowitz, Finlay A. McAlister

    Résumé Résumé Plan Plan  
  • ·Extent of coronary artery disease and outcomes after ticagrelor administration in patients with an acute coronary syndrome: Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial

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    Anna Kotsia, Emmanouil S. Brilakis, Claes Held, Christopher Cannon, Gabriel P. Steg, Bernhard Meier, Frank Cools, Marc J. Claeys, Jan H. Cornel, Philip Aylward, Basil S. Lewis, Douglas Weaver, Gunnar Brandrup-Wognsen, Susanna R. Stevens, Anders Himmelmann, Lars Wallentin, Stefan K. James

    Résumé Résumé Plan Plan  
  • ·Impact of smoking status on platelet function and clinical outcomes with prasugrel vs. clopidogrel in patients with acute coronary syndromes managed without revascularization: Insights from the TRILOGY ACS trial

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    Jan H. Cornel, E. Magnus Ohman, Benjamin Neely, Peter Clemmensen, Piyamitr Sritara, Dmitry Zamoryakhin, Paul W. Armstrong, Dorairaj Prabhakaran, Harvey D. White, Keith A.A. Fox, Paul A. Gurbel, Matthew T. Roe, for the TRILOGY ACS Investigators

    Résumé Résumé Plan Plan  
  • ·Adipose-derived regenerative cells in patients with ischemic cardiomyopathy: The PRECISE Trial

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    Emerson C. Perin, Ricardo Sanz-Ruiz, Pedro L. Sánchez, José Lasso, Rosa Pérez-Cano, Juan C. Alonso-Farto, Esther Pérez-David, Maria Eugenia Fernández-Santos, Patrick W. Serruys, Henrick J. Duckers, Jens Kastrup, Steven Chamuleau, Yi Zheng, Guilherme V. Silva, James T. Willerson, Francisco Fernández-Avilés

    Résumé Résumé Plan Plan  
  • ·Polymorphism of the cystatin C gene in patients with acute coronary syndromes: Results from the PLATelet inhibition and patient Outcomes study

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    Axel Åkerblom, Niclas Eriksson, Lars Wallentin, Agneta Siegbahn, Bryan J. Barratt, Richard C. Becker, Andrzej Budaj, Anders Himmelmann, Steen Husted, Robert F. Storey, Åsa Johansson, Stefan K. James, for the PLATO Investigators

    Résumé Résumé Plan Plan  
  • ·Delay in reperfusion with transradial percutaneous coronary intervention for ST-elevation myocardial infarction: Might some delays be acceptable?

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    Neil J. Wimmer, David J. Cohen, Jason H. Wasfy, Saif S. Rathore, Laura Mauri, Robert W. Yeh

    Résumé Résumé Plan Plan  
  • ·Preprocedural statin use in patients undergoing percutaneous coronary intervention

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    Mohamad Kenaan, Milan Seth, Herbert D. Aronow, Joseph Naoum, Douglas Wunderly, James Mitchiner, Mauro Moscucci, Hitinder S. Gurm, Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2)

    Résumé Résumé Plan Plan  
  • ·Nocturnal patterns of heart rate and the risk of mortality after acute myocardial infarction

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    Robert M. Carney, Brian Steinmeyer, Kenneth E. Freedland, Phyllis K. Stein, Junichiro Hayano, James A. Blumenthal, Allan S. Jaffe

    Résumé Résumé Plan Plan  
  • ·Dexamethasone for the prevention of postpericardiotomy syndrome: A DExamethasone for Cardiac Surgery substudy

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    Jeroen J.H. Bunge, Dirk van Osch, Jan M. Dieleman, Kirolos A. Jacob, Jolanda Kluin, Diederik van Dijk, Hendrik M. Nathoe, Dexamethasone for Cardiac Surgery (DECS) Study Group e

    Résumé Résumé Plan Plan  

• Letters to the Editor

  • ·Letter to the editor concerning the rationale and design of the X-VERT trial by Ezekowitz et al

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    Marta Za??ska-Koci?cka, Jannina St?pi?ska

    
  • ·Prognosis of elderly ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention

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    Albert Ariza-Solé, Francesc Formiga, Eva Bernal, Joel Salazar-Mendiguchía

    
  • ·Response to the letter to the editor by Ariza-Solé et al

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    Matthijs A. Velders, Stefan K. James, Berglind Libungan, Giovanna Sarno, Ole Fröbert, Jörg Carlsson, Martin J. Schalij, Per Albertsson, Bo Lagerqvist