Sommaire

• • ·Table of Contents

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• • ·Editorial Board

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• • ·Information for Authors

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• • ·Information for Readers

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• Editorial

  • ·Are we letting good stories obscure the truth—Can qualitative techniques provide clarification?

    Page :597-598

    John K. French, Jennifer A. Shearer

    

• Trial Design

  • ·Comparison of ticagrelor, the first reversible oral P2Y₁₂ receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) trial

    Page :599-605

    Stefan James, Axel Åkerblom, Christopher P. Cannon, Håkan Emanuelsson, Steen Husted, Hugo Katus, Allan Skene, Philippe Gabriel Steg, Robert F. Storey, Robert Harrington, Richard Becker, Lars Wallentin

    Résumé Résumé Plan Plan
  • ·Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis

    Page :606-612

    Matthew C. Becker, Thomas H. Wang, Lisa Wisniewski, Kathy Wolski, Peter Libby, Thomas F. Lüscher, Jeffrey S. Borer, Alice M. Mascette, M. Elaine Husni, Daniel H. Solomon, David Y. Graham, Neville D. Yeomans, Henry Krum, Frank Ruschitzka, A. Michael Lincoff, Steven E. Nissen, for the PRECISION Investigators

    Résumé Résumé Plan Plan  
  • ·Rationale and design of the Study Assessing the Effect of Cardiovascular Medications Provided as Low-cost, Evidence-based Generic Samples (SAMPLES) trial

    Page :613-619

    William H. Shrank, Niteesh K. Choudhry, Daniel H. Solomon, Thomas M. Snedden, Thomas H. Lee, Robert J. Glynn, Theresa V. Brown, Caitlin Jolda, Michelle Spetman, Maurice Alan Brookhart, Sebastian Schneeweiss, Jerry Avorn

    Résumé Résumé Plan Plan
  • ·Rationale and design of a randomized, double-blind, placebo-controlled trial of 6 versus 12 months clopidogrel therapy after implantation of a drug-eluting stent: The Intracoronary Stenting and Antithrombotic Regimen: Safety And EFficacy of 6 Months Dual Antiplatelet Therapy After Drug-Eluting Stenting (ISAR-SAFE) study

    Page :620

    Robert A. Byrne, Stefanie Schulz, Julinda Mehilli, Raisuke Iijima, Steffen Massberg, Franz-Josef Neumann, Jurri?n M. ten Berg, Albert Schömig, Adnan Kastrati, for the Intracoronary Stenting and Antithrombotic Regimen: Safety And EFficacy of Six Months Dual Antiplatelet Therapy After Drug-Eluting Stenting (ISAR-SAFE) Investigators

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• Review Articles

  • ·Dosing considerations in the use of intravenous prostanoids in pulmonary arterial hypertension: An experience-based review

    Page :625-635

    Ronald J. Oudiz, Harrison W. Farber

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  • ·Correction

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  • ·Aborted myocardial infarction: Is it real in the troponin era?

    Page :636-641

    Vlad C. Vasile, Luciano Babuin, Henry H. Ting, Malcolm R. Bell, Nicholas M. Orme, Brandon Y. Yuan, Jose A. Rio Perez, Jorge R. Alegria, Fernanda Bellolio, Luis H. Haro, Allan S. Jaffe

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• Clinical Investigations

  • ·Temporal trends and patterns of early clopidogrel use across the spectrum of acute coronary syndromes

    Page :642

    Rajeev V. Rao, Shaun G. Goodman, Raymond T. Yan, Frederick A. Spencer, Keith A. Fox, J. Paul DeYoung, Barry Rose, François R. Grondin, Richard Gallo, Joel M. Gore, Andrew T. Yan, on behalf of the Canadian Global Registry of Acute Coronary Events (GRACE/GRACE2) Investigators

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  • ·Evaluation and management of thrombocytopenia and suspected heparin-induced thrombocytopenia in hospitalized patients: The Complications After Thrombocytopenia Caused by Heparin (CATCH) registry

    Page :651-657

    Eric M. Crespo, Gustavo B.F. Oliveira, Emily F. Honeycutt, Richard C. Becker, Peter B. Berger, David J. Moliterno, Kevin J. Anstrom, Charles S. Abrams, Neal S. Kleiman, Stephan Moll, Lawrence Rice, Jo E. Rodgers, Steven R. Steinhubl, Victor F. Tapson, Christopher B. Granger, E. Magnus Ohman, on behalf of the CATCH Registry Investigators

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  • ·Ethnic variation in adverse cardiovascular outcomes and bleeding complications in the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) study

    Page :658-665

    Koon-Hou Mak, Deepak L. Bhatt, Mingyuan Shao, Graeme J. Hankey, J. Donald Easton, Keith A.A. Fox, Eric J. Topol

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  • ·Impact of stress testing before percutaneous coronary intervention or medical management on outcomes of patients with persistent total occlusion after myocardial infarction: Analysis from the occluded artery trial

    Page :666-672

    Warren J. Cantor, Sergio B. Baptista, Vankeepuram S. Srinivas, Camille A. Pearte, Venu Menon, Zygmunt Sadowski, John R. Ross, Peter Meciar, Eugenia Nikolsky, Sandra A. Forman, Gervasio A. Lamas, Judith S. Hochman

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  • ·Thrombolysis in Myocardial Infarction (TIMI) Risk Index predicts long-term mortality and heart failure in patients with ST-elevation myocardial infarction in the TIMI 2 clinical trial

    Page :673

    Quynh A. Truong, Christopher P. Cannon, Neil A. Zakai, Ian S. Rogers, Robert P. Giugliano, Stephen D. Wiviott, Carolyn H. McCabe, David A. Morrow, Eugene Braunwald

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  • ·Aldosterone and long-term outcome after myocardial infarction: A substudy of the french nationwide Observatoire sur la Prise en charge hospitalière, l'Evolution à un an et les caRactéristiques de patients présentant un infArctus du myocarde avec ou sans onde Q (OPERA) study

    Page :680-687

    Farzin Beygui, Gilles Montalescot, Eric Vicaut, Stephanie Rouanet, Eric Van Belle, Cathrine Baulac, Alexia Degrandsart, Jean Dallongeville, on behalf of the OPERA Investigators

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  • ·Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared to low- and high-dose simvastatin monotherapy

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    Subha L. Airan-Javia, Ronald L. Wolf, Megan L. Wolfe, Mahlet Tadesse, Emile Mohler, Muredach P. Reilly

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  • ·Chronic kidney disease and dipstick proteinuria are risk factors for stent thrombosis in patients with myocardial infarction

    Page :688-694

    Nathan D. Lambert, Matthew T. Sacrinty, Terry R. Ketch, Samuel J. Turner, Renato M. Santos, Kurt R. Daniel, Robert J. Applegate, Michael A. Kutcher, David C. Sane

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  • ·Persistent reservations against contradicted percutaneous coronary intervention indications: Citation content analysis

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    George C.M. Siontis, Athina Tatsioni, Demosthenes G. Katritsis, John P.A. Ioannidis

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  • ·Implantable cardioverter-defibrillator deactivation at the end of life: A physician survey

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    Amy S. Kelley, M. Carrington Reid, David H. Miller, Joseph J. Fins, Mark S. Lachs

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  • ·The association between socioeconomic status of high-risk patients with coronary heart disease and the treatment rates of evidence-based medicine for coronary heart disease secondary prevention in China: Results from the Bridging the Gap on CHD Secondary Prevention in China (BRIG) Project

    Page :709

    Shaoli Niu, Dong Zhao, Junren Zhu, Jun Liu, Qun Liu, Jing Liu, Wei Wang, Sidney C. Smith, on behalf of BRIG project

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  • ·Incidence, distribution, and prognostic impact of occluded culprit arteries among patients with non–ST-elevation acute coronary syndromes undergoing diagnostic angiography

    Page :716-723

    Tracy Y. Wang, Min Zhang, Yuling Fu, Paul W. Armstrong, L. Kristin Newby, C. Michael Gibson, David J. Moliterno, Frans Van de Werf, Harvey D. White, Robert A. Harrington, Matthew T. Roe

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  • ·Late coronary intervention for totally occluded left anterior descending coronary arteries in stable patients after myocardial infarction: Results from the Occluded Artery Trial (OAT)

    Page :724-732

    Lukasz A. Malek, Harmony R. Reynolds, Sandra A. Forman, Carlos Vozzi, G.B. John Mancini, John K. French, Mieczyslaw Dziarmaga, Jean P. Renkin, Janusz Kochman, Gervasio A. Lamas, Judith S. Hochman

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  • ·Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: A randomized, controlled study

    Page :733-739

    Yaling Han, Yi Li, Shouli Wang, Quanmin Jing, Zhulu Wang, Dongmei Wang, Qingfen Shu, Xiuying Tang

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  • ·Impact of female gender and transradial coronary stenting with maximal antiplatelet therapy on bleeding and ischemic outcomes

    Page :740-745

    Helena Tizón-Marcos, Olivier F. Bertrand, Josep Rodés-Cabau, Éric Larose, Valérie Gaudreault, Rodrigo Bagur, Onil Gleeton, Javier Courtis, Louis Roy, Paul Poirier, Olivier Costerousse, Robert De Larochellière

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  • ·Screening the population for left ventricular hypertrophy and left ventricular systolic dysfunction using natriuretic peptides: Results from the Dallas Heart Study

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    James A. de Lemos, Darren K. McGuire, Amit Khera, Sandeep R. Das, Sabina A. Murphy, Torbjorn Omland, Mark H. Drazner

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  • ·Influence of patient age and sex on delivery of guideline-recommended heart failure care in the outpatient cardiology practice setting: Findings from IMPROVE HF

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    Clyde W. Yancy, Gregg C. Fonarow, Nancy M. Albert, Anne B. Curtis, Wendy Gattis Stough, Mihai Gheorghiade, J. Thomas Heywood, Mark L. McBride, Mandeep R. Mehra, Christopher M. O'Connor, Dwight Reynolds, Mary Norine Walsh

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  • ·Diastolic dysfunction and left atrial enlargement as contributing factors to functional mitral regurgitation in dilated cardiomyopathy: Data from the Acorn trial

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    Seong-Mi Park, Seung Woo Park, Grace Casaclang-Verzosa, Steve R. Ommen, Patricia A. Pellikka, Fletcher A. Miller, Maurice E. Sarano, Spencer H. Kubo, Jae K. Oh

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  • ·Glucose levels compared with diabetes history in the risk assessment of patients with acute myocardial infarction

    Page :763-770

    Abhinav Goyal, Shamir R. Mehta, Hertzel C. Gerstein, Rafael Díaz, Rizwan Afzal, Denis Xavier, Jun Zhu, Prem Pais, Liu Lisheng, Khawar A. Kazmi, Mohammad Zubaid, Leopoldo S. Piegas, Petr Widimsky, Andrzej Budaj, Alvaro Avezum, Salim Yusuf

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  • ·Differences in heart rate response to adenosine and regadenoson in patients with and without diabetes mellitus

    Page :771-776

    Fadi G. Hage, Jaekyeong Heo, Billy Franks, Luiz Belardinelli, Brent Blackburn, Whedy Wang, Ami E. Iskandrian

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  • ·Candidate genetic variants in the fibrinogen, methylenetetrahydrofolate reductase, and intercellular adhesion molecule-1 genes and plasma levels of fibrinogen, homocysteine, and intercellular adhesion molecule-1 among various race/ethnic groups: Data from the Women's Genome Health Study

    Page :777

    Michelle A. Albert, Guillaume Pare, Alanna Morris, Lynda Rose, Julie Buring, Paul M. Ridker, Robert Y.L. Zee

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  • ·Use of a nurse-led intervention to optimize beta-blockade for reducing cardiac events after major noncardiac surgery

    Page :784-790

    Thomas H. Marwick, Helen Branagan, Bala Venkatesh, Simon Stewart, on behalf of the STRATIFY investigators

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  • ·Assessment of left ventricular dyssynchrony and function using real-time 3-dimensional echocardiography in patients with congenital right heart disease

    Page :791-798

    Tanja M. Raedle-Hurst, Matthias Mueller, Axel Rentzsch, Hans-Joachim Schaefers, Eva Herrmann, Hashim Abdul-Khaliq

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• Letters to the Editor

  • ·The challenge of the volume status assessment in heart failure

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    Gaspare Parrinello, Daniele Torres, Salvatore Paterna, Pietro Di Pasquale, Manuela Mezzero, Giuseppe Licata

    
  • ·Response to letter-to-the-editor by Torres et al

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    Viviane Nguyen

    
  • ·Letter to the Editor

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    W.M.N. Ratnayake

    
  • ·Response to Letter to the Editor by Block et al

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    Robert Block