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• • ·Cover 1

    Page :OFC

    
• • ·Brief Overview of This Month's JACI

    Page :3A

    
• • ·Table of Contents

    Page :6A

    
• • ·Editorial Board

    Page :25A

    

• Reader services

  • ·Information for Readers

    Page :26A

    
  • ·News & Notes

    Page :28A

    Plan Plan  
  • ·CME Activities Calendar

    Page :33A

    Plan Plan

• News beyond our pages

  • ·News Beyond Our Pages

    Page :1-2

    Marc E. Rothenberg, Jean Bousquet

    Plan Plan  

• Reviews and feature articles

  • ·Eosinophilic esophagitis: Updated consensus recommendations for children and adults

    Page :3

    Chris A. Liacouras, Glenn T. Furuta, Ikuo Hirano, Dan Atkins, Stephen E. Attwood, Peter A. Bonis, A. Wesley Burks, Mirna Chehade, Margaret H. Collins, Evan S. Dellon, Ranjan Dohil, Gary W. Falk, Nirmala Gonsalves, Sandeep K. Gupta, David A. Katzka, Alfredo J. Lucendo, Jonathan E. Markowitz, Richard J. Noel, Robert D. Odze, Philip E. Putnam, Joel E. Richter, Yvonne Romero, Eduardo Ruchelli, Hugh A. Sampson, Alain Schoepfer, Nicholas J. Shaheen, Scott H. Sicherer, Stuart Spechler, Jonathan M. Spergel, Alex Straumann, Barry K. Wershil, Marc E. Rothenberg, Seema S. Aceves

    Résumé Résumé Plan Plan  
  • ·Eosinophilic esophagitis: Updated consensus recommendations for children and adults

    Page :21-22

    
  • ·Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies

    Page :23-32

    Joseph D. Sherrill, Marc E. Rothenberg

    Résumé Résumé Plan Plan  
  • ·Genetic dissection of eosinophilic esophagitis provides insight into disease pathogenesis and treatment strategies

    Page :33-34

    

• The Editors' choice

  • ·The Editors’ Choice

    Page :35-36

    Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI

    Plan Plan  

• Asthma and lower airway disease

  • ·Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations

    Page :37

    Joshua M. Galanter, Dara Torgerson, Christopher R. Gignoux, Saunak Sen, Lindsey A. Roth, Marc Via, Melinda C. Aldrich, Celeste Eng, Scott Huntsman, Jose Rodriguez-Santana, William Rodriguez-Cintrón, Rocio Chapela, Jean G. Ford, Esteban G. Burchard

    Résumé Résumé Plan Plan  
  • ·Further validation and definition of the psychometric properties of the Asthma Impact Survey

    Page :44

    Michael Schatz, Robert S. Zeiger, Su-Jau Yang, Wansu Chen, Mark Kosinski

    Résumé Résumé Plan Plan
  • ·Reduced breath condensate pH in asymptomatic children with prior wheezing as a risk factor for asthma

    Page :50-55

    Marie von Jagwitz, Frank Pessler, Manas Akmatov, Jialiang Li, Ursula Range, Christian Vogelberg

    Résumé Résumé Plan Plan  
  • ·Achieving and maintaining asthma control in inner-city children

    Page :56-63

    Lyne Scott, Tricia Morphew, Mary E. Bollinger, Steve Samuelson, Stanley Galant, Loran Clement, Karen O’Cull, Felita Jones, Craig A. Jones

    Résumé Résumé Plan Plan  
  • ·Inner-city asthma: Control can be achieved!

    Page :64-65

    Rebecca S. Gruchalla

    Plan Plan

• Rhinitis, sinusitis, and upper airway disease

  • ·Reduced expression of COXs and production of prostaglandin E₂ in patients with nasal polyps with or without aspirin-intolerant asthma

    Page :66

    Jordi Roca-Ferrer, Francesc J. Garcia-Garcia, Javier Pereda, Maria Perez-Gonzalez, Laura Pujols, Isam Alobid, Joaquim Mullol, Cesar Picado

    Résumé Résumé Plan Plan  
  • ·Increased expression of the chemokine CCL23 in eosinophilic chronic rhinosinusitis with nasal polyps

    Page :73

    Julie A. Poposki, Ashraf Uzzaman, Deepti R. Nagarkar, Regina T. Chustz, Anju T. Peters, Lydia A. Suh, Roderick Carter, James Norton, Kathleen E. Harris, Leslie C. Grammer, Bruce K. Tan, Rakesh K. Chandra, David B. Conley, Robert C. Kern, Robert P. Schleimer, Atsushi Kato

    Résumé Résumé Plan Plan  

• Atopic dermatitis and skin disease

  • ·Staphylococcus aureus fibronectin-binding protein specifically binds IgE from patients with atopic dermatitis and requires antigen presentation for cellular immune responses

    Page :82

    Kavita Reginald, Kerstin Westritschnig, Birgit Linhart, Margarete Focke-Tejkl, Beatrice Jahn-Schmid, Julia Eckl-Dorna, Annice Heratizadeh, Angelika Stöcklinger, Nadja Balic, Susanne Spitzauer, Verena Niederberger, Thomas Werfel, Josef Thalhamer, Stephan Weidinger, Natalija Novak, Markus Ollert, Alexander M. Hirschl, Rudolf Valenta

    Résumé Résumé Plan Plan  
  • ·Malassezia sympodialis thioredoxin–specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis

    Page :92

    Hari Balaji, Annice Heratizadeh, Katja Wichmann, Margarete Niebuhr, Reto Crameri, Annika Scheynius, Thomas Werfel

    Résumé Résumé Plan Plan  
  • ·Autoreactive CD4⁺ T cells in patients with atopic dermatitis

    Page :100-101

    Eddie A. James, William W. Kwok

    

• Food, drug, insect sting allergy, and anaphylaxis

  • ·Invariant natural killer T cells from children with versus without food allergy exhibit differential responsiveness to milk-derived sphingomyelin

    Page :102

    Soma Jyonouchi, Valsamma Abraham, Jordan S. Orange, Jonathan M. Spergel, Laura Gober, Emily Dudek, Rushani Saltzman, Kim E. Nichols, Antonella Cianferoni

    Résumé Résumé Plan Plan  
  • ·Estimating the economic burden of food-induced allergic reactions and anaphylaxis in the United States

    Page :110

    Dipen A. Patel, David A. Holdford, Eric Edwards, Norman V. Carroll

    Résumé Résumé Plan Plan  
  • ·Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses

    Page :116-124

    Chris J. Corrigan, Wei Wang, Qiu Meng, Cailong Fang, Ghada Eid, M. Rosario Caballero, Ze Lv, Yunqing An, Yui-Hsi Wang, Yong-Jun Liu, A. Barry Kay, Tak H. Lee, Sun Ying

    Résumé Résumé Plan Plan  
  • ·Dietary baked milk accelerates the resolution of cow’s milk allergy in children

    Page :125

    Jennifer S. Kim, Anna Nowak-Węgrzyn, Scott H. Sicherer, Sally Noone, Erin L. Moshier, Hugh A. Sampson

    Résumé Résumé Plan Plan  
  • ·Long-term outcomes in pediatric-onset esophageal eosinophilia

    Page :132-138

    Charles W. DeBrosse, James P. Franciosi, Eileen C. King, Bridget K. Buckmeier Butz, Allison B. Greenberg, Margaret H. Collins, J. Pablo Abonia, Amal Assa’ad, Philip E. Putnam, Marc E. Rothenberg

    Résumé Résumé Plan Plan  

• Immune deficiencies, infection, and systemic immune disorders

  • ·Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia

    Page :139-146

    Miguel A. de la Fuente, Mike Recher, Nicholas L. Rider, Kevin A. Strauss, D. Holmes Morton, Margaret Adair, Francisco A. Bonilla, Hans D. Ochs, Erwin W. Gelfand, Itai M. Pessach, Jolan E. Walter, Alejandra King, Silvia Giliani, Sung-Yun Pai, Luigi D. Notarangelo

    Résumé Résumé Plan Plan  
  • ·Mast cell activation syndrome: A newly recognized disorder with systemic clinical manifestations

    Page :147

    Matthew J. Hamilton, Jason L. Hornick, Cem Akin, Mariana C. Castells, Norton J. Greenberger

    Résumé Résumé Plan Plan  
  • ·Ecallantide (DX-88) for acute hereditary angioedema attacks: Integrated analysis of 2 double-blind, phase 3 studies

    Page :153

    Albert L. Sheffer, Marilyn Campion, Robyn J. Levy, H. Henry Li, Patrick T. Horn, William E. Pullman

    Résumé Résumé Plan Plan  

• Mechanisms of allergy and clinical immunology

  • ·Inhibition of house dust mite–induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment

    Page :160

    Adam Collison, Joerg Mattes, Maximilian Plank, Paul S. Foster

    Résumé Résumé Plan Plan  
  • ·T_H17 cells mediate pulmonary collateral priming

    Page :168

    Melanie Albrecht, Hui-Chen Chen, Paula Preston-Hurlburt, Patricia Ranney, Heinz-Gerd Hoymann, Joachim Maxeiner, Valérie Staudt, Christian Taube, H. Kim Bottomly, Anna-Maria Dittrich

    Résumé Résumé Plan Plan  
  • ·Carrier-bound, nonallergenic Ole e 1 peptides for vaccination against olive pollen allergy

    Page :178

    Teresa E. Twaroch, Margit Focke, Vera Civaj, Milena Weber, Nadja Balic, Adriano Mari, Rosetta Ferrara, Santiago Quirce, Susanne Spitzauer, Ines Swoboda, Rudolf Valenta

    Résumé Résumé Plan Plan  
  • ·Mold allergen sensitization in adult asthma according to integrin β3 polymorphisms and Toll-like receptor 2/+596 genotype

    Page :185

    Lidwien A.M. Smit, Emmanuelle Bouzigon, Jean Bousquet, Nicole Le Moual, Rachel Nadif, Isabelle Pin, Mark Lathrop, Florence Demenais, Francine Kauffmann, Valérie Siroux, Epidemiological Study on the Genetics and Environment of Asthma

    Résumé Résumé Plan Plan  
  • ·Lung dendritic cells induce T_H17 cells that produce T_H2 cytokines, express GATA-3, and promote airway inflammation

    Page :192

    Marianne Raymond, Vu Quang Van, Keiko Wakahara, Manuel Rubio, Marika Sarfati

    Résumé Résumé Plan Plan  
  • ·Efficacy and safety of omalizumab in patients with chronic urticaria who exhibit IgE against thyroperoxidase

    Page :202

    Marcus Maurer, Sabine Altrichter, Thomas Bieber, Tilo Biedermann, Matthias Bräutigam, Stefan Seyfried, Randolf Brehler, Jürgen Grabbe, Nicolas Hunzelmann, Thilo Jakob, Andreas Jung, Jörg Kleine-Tebbe, Martin Mempel, Michael Meurer, Kristian Reich, Franziska Ruëff, Knut Schäkel, Kaushik Sengupta, Christian Sieder, Jan C. Simon, Bettina Wedi, Torsten Zuberbier, Vera Mahler, Petra Staubach

    Résumé Résumé Plan Plan  

• Letters to the Editor

  • ·American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma & Immunology Omalizumab-Associated Anaphylaxis Joint Task Force follow-up report

    Page :210-212

    Linda Cox, Phillip Lieberman, Dana Wallace, F. Estelle R. Simons, Ira Finegold, Thomas Platts-Mills, Lawrence Schwartz

    
  • ·Diacylglycerol kinase ζ deficiency in a non-CD4⁺ T-cell compartment leads to increased peanut hypersensitivity

    Page :212-214

    Mike Kulis, Chi-Keung Wan, Balachandra K. Gorentla, A. Wesley Burks, Xiao-Ping Zhong

     
  • ·Children in the inner city of New York have high rates of food allergy and IgE sensitization to common foods

    Page :214-215

    Jennifer M. Maloney, Anna Nowak-Węgrzyn, Julie Wang

    
  • ·Anaphylaxis to diphtheria, tetanus, and pertussis vaccines among children with cow’s milk allergy

    Page :215-218

    Jacob D. Kattan, George N. Konstantinou, Amanda L. Cox, Anna Nowak-Węgrzyn, Gustavo Gimenez, Hugh A. Sampson, Scott H. Sicherer

    
  • ·Single-dose influenza vaccination of patients with egg allergy in a multicenter study

    Page :218-219

    Luke Webb, Maureen Petersen, Stephen Boden, Virginia LaBelle, J. Andrew Bird, Druhan Howell, A. Wesley Burks, Susan Laubach

    
  • ·Topical intranasal ioxaglate meglumine 39.3% and ioxaglate sodium 19.6% (Hexabrix) reduces the acute response to nasal challenge with allergen

    Page :219-221

    Shilpa Vishwanath, Fuad M. Baroody, Mohamad R. Chaaban, Marcella deTineo, Kenneth H. Lasser, Elliot C. Lasser, Robert M. Naclerio

     
  • ·Asthma and biofilm-forming bacteria are independently associated with revision sinus surgeries for chronic rhinosinusitis

    Page :221

    Zi Zhang, Darren R. Linkin, Brian S. Finkelman, Bert W. O’Malley, Erica R. Thaler, Laurel Doghramji, David W. Kennedy, Noam A. Cohen, James N. Palmer

    
  • ·Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects

    Page :223

    Noriko Nakagawa, Kohsuke Imai, Hirokazu Kanegane, Hiroki Sato, Masafumi Yamada, Kensuke Kondoh, Satoshi Okada, Masao Kobayashi, Kazunaga Agematsu, Hidetoshi Takada, Noriko Mitsuiki, Koichi Oshima, Osamu Ohara, Deepti Suri, Amit Rawat, Surjit Singh, Qiang Pan-Hammarström, Lennart Hammarström, Janine Reichenbach, Reinhard Seger, Tadashi Ariga, Toshiro Hara, Toshio Miyawaki, Shigeaki Nonoyama

     
  • ·Functional analysis of transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) mutations associated with common variable immunodeficiency

    Page :226

    Ari J. Fried, Ingrid Rauter, Stacey R. Dillon, Haifa H. Jabara, Raif S. Geha

     
  • ·Association of anti-IgA antibodies with adverse reactions to γ-globulin infusion

    Page :228

    Rima Rachid, Mariana Castells, Charlotte Cunningham-Rundles, Francisco A. Bonilla

    
  • ·Occurrence of myelodysplastic syndrome in 2 patients with reticular dysgenesis

    Page :230

    Chantal Lagresle-Peyrou, Bénédicte Neven, Emmanuelle Six, Capucine Picard, Corinne Demerens-de Chappedelaine, Yves Bertrand, Nada Jabado, Christine Chomienne, Isabelle Radford-Weiss, Chantal Brouzes, Vahid Asnafi, Elizabeth MacIntyre, Jean Donadieu, Blandine Beaupain, Pierre Fenaux, Virginie Eclache, Alain Fischer, Marina Cavazzana-Calvo

     
  • ·Hereditary angioedema: Key role for kallikrein and bradykinin in vascular endothelial-cadherin cleavage and edema formation

    Page :232-234

    Laurence Bouillet, Tiphaine Mannic, Mélanie Arboleas, Mariela Subileau, Christian Massot, Christian Drouet, Philippe Huber, Isabelle Vilgrain

     
  • ·In vivo maturation of T_H cells in relation to atopy

    Page :234

    Dominique M.A. Bullens, Ahmad Kasran, Ellen Dilissen, Kathleen De Swert, Lieve Coorevits, Jacques Van Snick, Jan L. Ceuppens

     
  • ·Regulatory role of IL10 genetic variations in determining allergen-induced T_H2 cytokine responses in children

    Page :237

    Catherine M. Hayden, Guicheng Zhang, Parveenjeet K. Judge, Siew-Kim Khoo, Ingrid A. Laing, Stephen W. Turner, Jack Goldblatt, Patrick G. Holt, Peter N. Le Souëf

     
  • ·Monocyte chemotactic protein (MCP3) promoter polymorphism is associated with atopic asthma in the Indian population

    Page :239

    Jyotsna Batra, Sudipta Das, Rajshekhar Chatterjee, Sunandini Chandra, Balaram Ghosh

     
  • ·Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis

    Page :242

    Anna De Benedetto, Mark K. Slifka, Nicholas M. Rafaels, I-Hsin Kuo, Steve N. Georas, Mark Boguniewicz, Tissa Hata, Lynda C. Schneider, Jon M. Hanifin, Richard L. Gallo, David C. Johnson, Kathleen C. Barnes, Donald Y.M. Leung, Lisa A. Beck

     

• Correspondence

  • ·Detection of IgE to recombinant Api m 1 and rVes v 5 is valuable but not sufficient to distinguish bee from wasp venom allergy

    Page :247-248

    Gunter J. Sturm, Wolfgang Hemmer, Thomas Hawranek, Roland Lang, Markus Ollert, Edzard Spillner, Simon Blank, Danijela Bokanovic, Werner Aberer

    
  • ·Reply

    Page :248

    S.C. Hofmann, Nikolai Pfender, Steffi Weckesser, Simon Blank, Johannes Huss-Marp, Edzard Spillner, Thilo Jakob

    
  • ·Peanut allergy and the impact of maternal consumption during pregnancy and breast-feeding

    Page :248-249

    Anne Des Roches, Philippe Bégin, Claire Infante-Rivard, Jean Paradis, Louis Paradis

    
  • ·Reply

    Page :249-250

    Scott H. Sicherer, Robert A. Wood, Donald Stablein, Robert Lindblad, A. Wesley Burks, Andrew H. Liu, Stacie M. Jones, David M. Fleischer, Donald Y.M. Leung, Hugh A. Sampson

    
  • ·Oral immunotherapy in food allergy: How difficult to weigh its risks and benefits?

    Page :250-251

    Mauro Calvani, Stefano Miceli Sopo, Valentina Giorgio

    
  • ·Reply

    Page :251

    Richard L. Wasserman, Robert W. Sugerman, Lyndon Mansfield, James W. Baker

    
  • ·Immediate-type hypersensitivity to systemic glucocorticoids: An underrated drug allergy

    Page :251

    Gianfranco Calogiuri, Elisabetta Di Leo, Eustachio Nettis, Angelo Vacca, Antonio Ferrannini

    
  • ·Reply

    Page :251-252

    Rima Rachid, David Leslie, Lynda Schneider, Frank Twarog

    
  • ·Correction

    Page :253