Sommaire

• • ·Cover 1

    Page :OFC

    
• • ·A Brief Overview of This Month’s JACI

    Page :7A

    
• • ·Table of Contents

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• • ·Editorial Board

    Page :28A

    

• Reader services

  • ·Information for Readers

    Page :30A

    
  • ·Footnotes¹

    Page :32A

    Plan Plan  
  • ·CME Activities Calendar

    Page :37A

    Plan Plan

• News beyond our pages

  • ·News Beyond Our Pages – July 2010

    Page :1-2

    Marc E. Rothenberg, Jean Bousquet

    Plan Plan  

• Reviews and feature articles

  • ·Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract

    Page :3-13

    Dagmar Simon, Andrew Wardlaw, Marc E. Rothenberg

    Résumé Résumé Plan Plan
  • ·Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract

    Page :14-15

    
  • ·What targeting eosinophils has taught us about their role in diseases

    Page :16-25

    Bruce S. Bochner, Gerald J. Gleich

    Résumé Résumé Plan Plan
  • ·What targeting eosinophils has taught us about their role in diseases

    Page :26-27

    
  • ·Intelligent granules: Are eosinophil crystalloid granules inimitable?

    Page :28-30

    Salahaddin Mahmudi-Azer, S.O. (Wole) Odemuyiwa, Redwan Moqbel

     
  • ·Peanut oral immunotherapy is not ready for clinical use

    Page :31-32

    Ananth Thyagarajan, Pooja Varshney, Stacie M. Jones, Scott Sicherer, Robert Wood, Brian P. Vickery, Hugh Sampson, A. Wesley Burks

    
  • ·Human IgE antibody serology: A primer for the practicing North American allergist/immunologist

    Page :33-38

    Robert G. Hamilton, P. Brock Williams, Specific IgE Testing Task Force of the American Academy of Allergy, Asthma & Immunology and the American College of Allergy, Asthma and Immunology

    Résumé Résumé Plan Plan  
  • ·Practical approach to the patient with hypereosinophilia

    Page :39-44

    Florence Roufosse, Peter F. Weller

    Résumé Résumé Plan Plan  
  • ·Refining the definition of hypereosinophilic syndrome

    Page :45-49

    Hans-Uwe Simon, Marc E. Rothenberg, Bruce S. Bochner, Peter F. Weller, Andrew J. Wardlaw, Michael E. Wechsler, Lanny J. Rosenwasser, Florence Roufosse, Gerald J. Gleich, Amy D. Klion

    Résumé Résumé Plan Plan  

• The Editors' choice

  • ·The Editors’ Choice

    Page :50-51

    Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI

    Plan Plan  

• Asthma and lower airway disease

  • ·Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study

    Page :52

    John M. Brehm, Brooke Schuemann, Anne L. Fuhlbrigge, Bruce W. Hollis, Robert C. Strunk, Robert S. Zeiger, Scott T. Weiss, Augusto A. Litonjua, Childhood Asthma Management Program Research Group ‡

    Résumé Résumé Plan Plan  
  • ·Eosinophil protein in airway macrophages: A novel biomarker of eosinophilic inflammation in patients with asthma

    Page :61

    Neeta S. Kulkarni, Fay Hollins, Amanda Sutcliffe, Ruth Saunders, Sachil Shah, Salman Siddiqui, Sumit Gupta, Pranab Haldar, Ruth Green, Ian Pavord, Andrew Wardlaw, Christopher E. Brightling

    Résumé Résumé Plan Plan  
  • ·Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults

    Page :70

    Somnath Mukhopadhyay, Joseph Sypek, Roger Tavendale, Ulrike Gartner, John Winter, Wei Li, Karen Page, Margaret Fleming, Jeff Brady, Margot O’Toole, Donald F. Macgregor, Samuel Goldman, Steve Tam, William Abraham, Cara Williams, Douglas K. Miller, Colin N.A. Palmer

    Résumé Résumé Plan Plan  
  • ·Vitamin D in asthma: Panacea or true promise?

    Page :59-60

    Adit A. Ginde, E. Rand Sutherland

    

• Food, drug, insect sting allergy, and anaphylaxis

  • ·Early exposure to cow’s milk protein is protective against IgE-mediated cow’s milk protein allergy

    Page :77

    Yitzhak Katz, Nelly Rajuan, Michael R. Goldberg, Eli Eisenberg, Eli Heyman, Adi Cohen, Moshe Leshno

    Résumé Résumé Plan Plan  
  • ·Oral peanut immunotherapy in children with peanut anaphylaxis

    Page :83

    Katharina Blumchen, Helen Ulbricht, Ute Staden, Kerstin Dobberstein, John Beschorner, Lucila Camargo Lopes de Oliveira, Wayne G. Shreffler, Hugh A. Sampson, Bodo Niggemann, Ulrich Wahn, Kirsten Beyer

    Résumé Résumé Plan Plan  
  • ·Targeting Toll-like receptors on dendritic cells modifies the T_H2 response to peanut allergens in vitro

    Page :92

    Pierre Pochard, Brian Vickery, M. Cecilia Berin, Alexander Grishin, Hugh A. Sampson, Michael Caplan, Kim Bottomly

    Résumé Résumé Plan Plan  
  • ·Algorithm for the diagnosis of anaphylaxis and its validation using population-based data on emergency department visits for anaphylaxis in Florida

    Page :98

    Laurel Harduar-Morano, Michael R. Simon, Sharon Watkins, Carina Blackmore

    Résumé Résumé Plan Plan  
  • ·Predictors of side effects during the buildup phase of venom immunotherapy for Hymenoptera venom allergy: The importance of baseline serum tryptase^†

    Page :105

    Franziska Ruëff, Bernhard Przybilla, Maria Beatrice Biló, Ulrich Müller, Fabian Scheipl, Werner Aberer, Joëlle Birnbaum, Anna Bodzenta-Lukaszyk, Floriano Bonifazi, Christoph Bucher, Paolo Campi, Ulf Darsow, Cornelia Egger, Gabrielle Haeberli, Thomas Hawranek, Iwona Kucharewicz, Helmut Küchenhoff, Roland Lang, Oliviero Quercia, Norbert Reider, Maurizio Severino, Michael Sticherling, Gunter Johannes Sturm, Brunello Wüthrich

    Résumé Résumé Plan Plan  
  • ·Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999

    Page :112-119

    Charles W. DeBrosse, Margaret H. Collins, Bridget K. Buckmeier Butz, Casey L. Allen, Eileen C. King, Amal H. Assa'ad, J. Pablo Abonia, Philip E. Putnam, Marc E. Rothenberg, James P. Franciosi

    Résumé Résumé Plan Plan  

• Immune deficiencies, infection, and systemic immune disorders

  • ·Recurrent and persistent respiratory tract viral infections in patients with primary hypogammaglobulinemia

    Page :120-126

    Leena Kainulainen, Tytti Vuorinen, Kaisu Rantakokko-Jalava, Riikka Österback, Olli Ruuskanen

    Résumé Résumé Plan Plan  
  • ·Immune deficiency caused by impaired expression of nuclear factor-κB essential modifier (NEMO) because of a mutation in the 5′ untranslated region of the NEMO gene

    Page :127

    Jana L. Mooster, Caterina Cancrini, Alessandra Simonetti, Paolo Rossi, Gigliola Di Matteo, Maria Luisa Romiti, Silvia Di Cesare, Luigi Notarangelo, Raif S. Geha, Douglas R. McDonald

    Résumé Résumé Plan Plan  

• Mechanisms of allergy and clinical immunology

  • ·Myeloid and plasmacytoid dendritic cells in induced sputum after allergen inhalation in subjects with asthma

    Page :133-139

    Benny Dua, Richard M. Watson, Gail M. Gauvreau, Paul M. O'Byrne

    Résumé Résumé Plan Plan  
  • ·Involvement of mast cells in eosinophilic esophagitis

    Page :140-149

    J. Pablo Abonia, Carine Blanchard, Bridget Buckmeier Butz, Heather F. Rainey, Margaret H. Collins, Keith Stringer, Philip E. Putnam, Marc E. Rothenberg

    Résumé Résumé Plan Plan   
  • ·A single nucleotide polymorphism in the CCR3 gene ablates receptor export to the plasma membrane

    Page :150

    Emma L. Wise, Kandace T. Bonner, Timothy J. Williams, James E. Pease

    Résumé Résumé Plan Plan  
  • ·Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis

    Page :160

    Joseph D. Sherrill, Pei-Song Gao, Emily M. Stucke, Carine Blanchard, Margaret H. Collins, Phil E. Putnam, James P. Franciosi, Jonathan P. Kushner, J. Pablo Abonia, Amal H. Assa’ad, Melinda Butsch Kovacic, Jocelyn M. Biagini Myers, Bruce S. Bochner, Hua He, Gurjit Khurana Hershey, Lisa J. Martin, Marc E. Rothenberg

    Résumé Résumé Plan Plan  
  • ·Mutations in CCR3 render it missing in action

    Page :158-159

    Paige Lacy, Ariel Munitz

    

• Letters to the Editor

  • ·2009 Seasonal and H1N1 influenza vaccination compliance in asthmatic children and adults

    Page :166-168

    Harvey L. Leo, Sarah J. Clark, Amy T. Butchart, Dianne C. Singer, Noreen M. Clark, Matthew M. Davis

    
  • ·Acute exacerbations of chronic rhinosinusitis occur in a distinct seasonal pattern

    Page :168-169

    Matthew A. Rank, Peter Wollan, Hirohito Kita, Barbara P. Yawn

     
  • ·Inflammatory responses of human eosinophils to cockroach are mediated through protease-dependent pathways

    Page :169

    Kota Wada, Yoshinori Matsuwaki, Juhan Yoon, Linda M. Benson, James L. Checkel, Theresa A. Bingemann, Hirohito Kita

     
  • ·Myeloid differentiation primary response gene 88 (MyD88) deficiency in a large kindred

    Page :172-175

    Daniel H. Conway, Jasmeen Dara, Asen Bagashev, Kathleen E. Sullivan

     
  • ·Mepolizumab does not alter levels of eosinophils, T cells, and mast cells in the duodenal mucosa in eosinophilic esophagitis

    Page :175-177

    Sébastien Conus, Alex Straumann, Eva Bettler, Hans-Uwe Simon

    
  • ·Selective allergic reactions to clavulanic acid: A report of 9 cases

    Page :177-179

    Leticia Sánchez-Morillas, Patricia Rojas Pérez-Ezquerra, Mar Reaño-Martos, José Julio Laguna-Martínez, María L. Sanz, Lorena Morales Martínez

    
  • ·Incidence of myeloproliferative hypereosinophilic syndrome in the United States and an estimate of all hypereosinophilic syndrome incidence

    Page :179-181

    Martin M. Crane, Cindy Ma Chang, Monica G. Kobayashi, Peter F. Weller

     
  • ·Differences in treatment of food challenge–induced reactions reflect physicians’ protocols more than reaction severity

    Page :182

    Yarden Yanishevsky, Deirdre Daly, Claire Cullinane, Jonathan O’B Hourihane

    
  • ·Reply

    Page :182-183

    Kirsi M. Järvinen, Sujitha Amalanayagam, S. Allan Bock, Wayne G. Shreffler, Sally Noone, Scott H. Sicherer, Hugh A. Sampson, Anna Nowak-Wegrzyn

    
  • ·Low-dose, but not high-dose, cyclosporin A promotes regulatory T-cell induction, expansion, or both

    Page :183-184

    Ria Baumgrass, Claudia Brandt, Fanny Wegner, Mandana Abdollahnia, Margitta Worm

    
  • ·Reply

    Page :184

    DirkJan Hijnen, Carla Bruijnzeel-Koomen, Edward Knol