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• Brief Communication

  • ·The Room Where It Happens: Clinician Reflections on Returning Preclinical Alzheimer’s Biomarker Results to Research Participants

    Page :1-6

    C.M. Erickson, N.A. Chin, F.B. Ketchum, M.L. Eveler, C.E. Conway, D.M. Coughlin, Lindsay R. Clark

    Résumé Résumé Plan Plan

• Original Research

  • ·Detection Rates of Mild Cognitive Impairment in Primary Care for the United States Medicare Population

    Page :7-12

    Ying Liu, H. Jun, A. Becker, C. Wallick, S. Mattke

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  • ·Association of Multi-Domain Factors with Cognition in the UK Biobank Study

    Page :13-21

    W.Y. Tan, C.A. Hargreaves, N. Kandiah, Saima Hilal

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• Review

  • ·How Modifiable Are Modifiable Dementia Risk Factors? A Framework for Considering the Modifiability of Dementia Risk Factors

    Page :22-37

    Lisa Bransby, E. Rosenich, P. Maruff, Y.Y. Lim

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• Original Research

  • ·Consistency between Treatment Effects on Clinical and Brain Atrophy Outcomes in Alzheimer’s Disease Trials

    Page :38-47

    M. ten Kate, F. Barkhof, Adam J. Schwarz

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  • ·Investigating the Factor Structure of the Preclinical Alzheimer Cognitive Composite and Cognitive Function Index across Racial/Ethnic, Sex, and Aβ Status Groups in the A4 Study

    Page :48-55

    M. Ruthirakuhan, M. Wood Alexander, H. Cogo-Moreira, T. Robinson, R. Amariglio, R.F. Buckley, R.A. Sperling, W. Swardfager, S.E. Black, J.S. Rabin

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• CTAD Task Force Paper

  • ·Neuropsychiatric Symptoms in AD: Clinical Trials Targeting Mild Behavioral Impairment: A Report from the International CTAD Task Force

    Page :56-64

    Maria Soto, P. Rosenberg, C. Ballard, B. Vellas, D. Miller, S. Gauthier, M.C. Carrillo, C. Lyketsos, Z. Ismail, Susan Abushakra, Mohammad Afshar, Sam Agus, Paul Aiden, John Alam, Alicia Algeciras-Schimnich, Sandrine Andrieu, Amos Baruch, Randall Bateman, Richard Batrla, Monika Baudler, Joanne Bell, Tobias Bittner, Sasha Bozeat, Joel Braunstein, Dawn Brooks, Tricia Brooks, Szofia Bullain, Jan Burmeister, Maria Carrillo, Min Cho, Emily Collins, Gavin Cook, Chris Dague, Susan De Santi, Rachelle Doody, Billy Dunn, Michael Egan, Sven Eriksson, Rianne Esquivel, Tom Fagan, Phyllis Ferrell, Howard Fillit, Michela Gallagher, Anna-Kaija Grönblad, Avis Hains, Harald Hampel, Oskar Hansson, Nanco Hefting, Suzanne Hendrix, Carole Ho, Helen Hu, Daryl Jones, Gene Kinney, Paul Kinnon, Ricky Kurzman, Lars Lannfelt, John Lawson, Nathalie LeBastard, Valérie Legrand, Nicole Lewandowski, Carine Lim, Donna Masterman, Colin Masters, Ming Lu, Mark Mintun, José Luis Molinuevo, Cecilia Monteiro, Bradford Navia, Tomas Odergren, Gunilla Osswald, Lewis Penny, Michael Pontecorvo, Anton Porsteinsson, Christine Rabe, Rema Raman, Gesine Respondek, Larisa Reyderman, Sharon Rogers, Paul Rosenberg, Sharon Rosenzweig-Lipson, Mark Roskey, Rubel Carrie, Ziad Saad, Stephen Salloway, Rachel Schindler, Dennis Selkoe, Melanie Shulman, John Sims, Kaycee Sink, Lisa Sipe, Daniel Skovronsky, Elizabeth Somers, Johannes Streffer, Pedro Such, Joyce Suhy, Masoud Toloue, Jacques Touchon, Manu Vandijck, Michael Weiner, Anne White, David Wilson, Wagner Zago, Jin Zhou, International CTAD Task Force members, EU/US CTAD Task force

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• Original Research

  • ·Phase 1/2a Intravenous and Subcutaneous Oligomer-Specific Antibody KHK6640 in Mild to Moderate Alzheimer’s Disease

    Page :65-70

    Marc Cantillon, N. Andreasen, N. Prins

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  • ·Expectancy Does Not Predict 18-month Treatment Outcomes with Cognitive Training in Mild Cognitive Impairment

    Page :71-78

    Jeffrey N. Motter, S.N. Rushia, M. Qian, C. Ndouli, A. Nwosu, J.R. Petrella, P.M. Doraiswamy, T.E. Goldberg, D.P. Devanand

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  • ·Digital Clock Drawing as an Alzheimer’s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults

    Page :79-87

    Louisa I. Thompson, M. Cummings, S. Emrani, D.J. Libon, A. Ang, C. Karjadi, R. Au, C. Liu

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  • ·Lifestyle and Socioeconomic Transition and Health Consequences of Alzheimer’s Disease and Other Dementias in Global, from 1990 to 2019

    Page :88-96

    Y. Cui, W. Yang, J. Shuai, Y. Ma, Yan Yan

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  • ·Burden of Illness in People with Alzheimer’s Disease: A Systematic Review of Epidemiology, Comorbidities and Mortality

    Page :97-107

    Krista L. Lanctôt, J. Hviid Hahn-Pedersen, C.S. Eichinger, C. Freeman, A. Clark, L.R.S. Tarazona, J. Cummings

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  • ·Modifiable Risk Factors for Accelerated Decline in Processing Speed: Results from Three Dutch Population Cohorts

    Page :108-116

    E. Jaarsma, A. Nooyens, Almar A.L. Kok, S. Köhler, M. van Boxtel, W.M.M. Verschuren, M. Huisman

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  • ·Relationships of Hypnotics with Incident Dementia and Alzheimer’s Disease: A Longitudinal Study and Meta-Analysis

    Page :117-129

    J.-H. Hou, S.-L. Sun, C.-C. Tan, Y.-M. Huang, L. Tan, Alzheimer’s Disease Neuroimaging Initiative, Wei Xu

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  • ·Association of Balance Impairment with Risk of Incident Dementia among Older Adults

    Page :130-137

    H.J. Kim, S. Jeong, Yun Hwan Oh, Michelle J. Suh, Jee Young Suh

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  • ·High-Fat Diet-Induced Diabetic Conditions Exacerbate Cognitive Impairment in a Mouse Model of Alzheimer’s Disease Via a Specific Tau Phosphorylation Pattern

    Page :138-148

    Y. Ito, Shuko Takeda, T. Nakajima, A. Oyama, H. Takeshita, K. Miki, Y. Takami, Y. Takeya, M. Shimamura, H. Rakugi, Ryuichi Morishita

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  • ·Computerized Cognitive Training in Mild Cognitive Impairment: Findings in African Americans and Caucasians

    Page :149-154

    Adaora Nwosu, M. Qian, J. Phillips, C.A. Hellegers, S. Rushia, J. Sneed, J.R. Petrella, T.E. Goldberg, D.P. Devanand, P.M. Doraiswamy

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  • ·Estimates of Current Capacity for Diagnosing Alzheimer’s Disease in Sweden and the Need to Expand Specialist Numbers

    Page :155-161

    Soeren Mattke, A. Gustavsson, L. Jacobs, S. Kern, S. Palmqvist, M. Eriksdotter, I. Skoog, B. Winblad, A. Wimo, L. Jönsson

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  • ·Cognitive Performance and Incident Alzheimer’s Dementia in Men Versus Women

    Page :162-170

    Ioannis Liampas, V. Siokas, C.G. Lyketsos, E. Dardiotis

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  • ·Global Energy Metabolism Deficit in Alzheimer Disease Brain

    Page :171-178

    Viharkumar Patel, J. Mill, O.C. Okonkwo, S. Salamat, L. Li, T. Raife

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  • ·Projected Savings to Canadian Provincial Budgets from Reduced Long-Term Care Home Utilization Due to a Disease-Modifying Alzheimer’s Treatment

    Page :179-184

    H. Jun, Z. Shi, Soeren Mattke

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  • ·Data-Driven Thresholding Statistically Biases ATN Profiling across Cohort Datasets

    Page :185-195

    Y. Salimi, D. Domingo-Fernández, M. Hofmann-Apitius, C. Birkenbihl, the Alzheimer’s Disease Neuroimaging Initiative, the Japanese Alzheimer’s Disease Neuroimaging Initiative, the Alzheimer’s Disease Repository Without Borders Investigators, the European Prevention of Alzheimer’s Disease (EPAD) Consortium

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  • ·Alzheimer’s Disease and Aging Association: Identification and Validation of Related Genes

    Page :196-213

    T. Liu, K. Hou, J. Li, T. Han, S. Liu, Jianshe Wei

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  • ·China Alzheimer’s Disease and Neurodegenerative Disorder Research (CANDOR) -A Prospective Cohort Study for Alzheimer’s Disease and Vascular Cognitive Impairment

    Page :214-221

    S. Li, H. Dong, Y. Wang, S. Wang, X. Lv, M. Dong, S. Tian, Jiong Shi

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  • ·The Therapeutic Effects of Noninvasive Brain Stimulation Combined with Cognitive Training in Elders with Alzheimer’s Disease or Amnesic Mild Cognitive Impairment

    Page :222-229

    J.-Y. Wang, J.-Y. Qin, J.-Y. Ye, W.-T. Li, M.-Q.-Z. Tong, Hui Ouyang, Fengxia Yan

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  • ·Association of Blood MicroRNA Expression and Polymorphisms with Cognitive and Biomarker Changes in Older Adults

    Page :230-240

    A. Sadlon, P. Takousis, E. Evangelou, I. Prokopenko, P. Alexopoulos, C.-M. Udeh-Momoh, G. Price, L. Middleton, Robert Perneczky, Alzheimer’s Disease Neuroimaging Initiative

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• Review

  • ·Are Population-Level Approaches to Dementia Risk Reduction Under-Researched? A Rapid Review of the Dementia Prevention Literature

    Page :241-248

    Sebastian Walsh, L. Wallace, I. Kuhn, O. Mytton, L. Lafortune, W. Wills, N. Mukadam, C. Brayne

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  • ·Oral Health as a Risk Factor for Alzheimer Disease

    Page :249-258

    S.M. Pruntel, B.C. van Munster, J.J. de Vries, A. Vissink, Anita Visser

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• Letter to the Editor

  • ·First Experiences with Amyloid-Related Imaging Abnormalities — Yet without Imaging that Can Rule Out Cerebral Injury or Monitor Efficacy of Recommended Management

    Page :259-260

    Poul F. Høilund-Carlsen, G. Perry, A. Alavi, J.R. Barrio

    

• Reply to the Letter to the Editor

  • ·Response to Concerns Raised on MRI Surveillance and Clinical Implications of ARIA in Disease Modifying Treatment

    Page :261-262

    Matthew D. Howe, M.C. Riddle, S.P. Salloway

    

• Erratum

  • ·Erratum to: Digital Clock Drawing as an Alzheimer’s Disease Susceptibility Biomarker: Associations with Genetic Risk Score and APOE in Older Adults

    Page :263

    Louisa I. Thompson, M. Cummings, S. Emrani, D.J. Libon, A. Ang, C. Karjadi, R. Au, C. Liu

    
  • ·Erratum to: Clinical Effects of Tramiprosate in APOE4/4 Homozygous Patients with Mild Alzheimer’s Disease Suggest Disease Modification Potential

    Page :264

    Susan Abushakra, A. Porsteinsson, P. Scheltens, C. Sadowsky, B. Vellas, J. Cummings, S. Gauthier, J.A. Hey, A. Power, P. Wang, L. Shen, M. Tolar