Sommaire

• • ·Editorial Board

    Article :115030

    

• Review Articles

  • ·Spectacular role of epididymis and bio-active cargo of nano-scale exosome in sperm maturation: A review

    Article :114889

    Waseem Ali, Kai Deng, Yusheng Bian, Zongping Liu, Hui Zou

    Résumé Résumé Plan Plan  
  • ·Research advances in endometriosis-related signaling pathways: A review

    Article :114909

    Manlin Zhang, Tongtong Xu, Deming Tong, Siman Li, Xiaodan Yu, Boya Liu, Lili Jiang, Kuiran Liu

    Résumé Résumé Plan Plan  
  • ·New insights into the roles of peroxiredoxins in cancer

    Article :114896

    Yan Liu, Pu Wang, Weina Hu, Da Chen

    Résumé Résumé Plan Plan  
  • ·Mechanisms of ferroptosis in Alzheimer's disease and therapeutic effects of natural plant products: A review

    Article :114312

    Da Zhao, Kailin Yang, Hua Guo, Jinsong Zeng, Shanshan Wang, Hao Xu, Anqi Ge, Liuting Zeng, Shaowu Chen, Jinwen Ge

    Résumé Résumé Plan Plan  
  • ·Therapeutic strategies for rheumatic diseases and disorders: targeting redox imbalance and oxidative stress

    Article :114900

    Muhammad Torequl Islam, Chandan Sarkar, Rajib Hossain, Md. Shimul Bhuia, Ileana Mardare, Marzhan Kulbayeva, Alibek Ydyrys, Daniela Calina, Solomon Habtemariam, Marek Kieliszek, Javad Sharifi-Rad, William C. Cho

    Résumé Résumé Plan Plan  
  • ·The impact of curcumin on migraine: A comprehensive review

    Article :114910

    Hajar Heidari, Mehrnaz Shojaei, Gholamreza Askari, Muhammed Majeed, Mohammad Bagherniya, George E. Barreto, Amirhossein Sahebkar

    Résumé Résumé Plan Plan  
  • ·Renal fibrosis in type 2 cardiorenal syndrome: An update on mechanisms and therapeutic opportunities

    Article :114901

    Xia Xu, Bingxuan Zhang, Yajiao Wang, Shuqing Shi, Jiayu Lv, Zhenyue Fu, Xiya Gao, Yumeng Li, Huaqin Wu, Qingqiao Song

    Résumé Résumé Plan Plan  
  • ·Molecular mechanistic pathways underlying the anticancer therapeutic efficiency of romidepsin

    Article :114774

    Nasreddine El Omari, Learn-Han Lee, Saad Bakrim, Hafiz A. Makeen, Hassan A. Alhazmi, Syam Mohan, Asaad Khalid, Long Chiau Ming, Abdelhakim Bouyahya

    Résumé Résumé Plan Plan  
  • ·Roles and mechanisms of natural drugs on sinus node dysfunction

    Article :114777

    Meilian Chen, Qiaomin Wu

    Résumé Résumé Plan Plan  
  • ·Advancing therapeutic strategies for Epstein-Barr virus-associated malignancies through lytic reactivation

    Article :114916

    Haiqi Tan, Yibing Gong, Yi Liu, Jingyi Long, Qingshuang Luo, Oluwasijibomi Damola Faleti, Xiaoming Lyu

    Résumé Résumé Plan Plan  
  • ·Potential crosstalk between pericytes and cathepsins in the tumour microenvironment

    Article :114932

    A. Mustafa, F. Elkhamisy, N. Arghiani, M.Z.I. Pranjol

    Résumé Résumé Plan Plan  
  • ·Spotlight on porphyrins: Classifications, mechanisms and medical applications

    Article :114933

    Fuyu Yang, Meiqi Xu, Xiaoyu Chen, Yakun Luo

    Résumé Résumé Plan Plan  
  • ·The roles, molecular interactions, and therapeutic value of CDK16 in human cancers

    Article :114929

    Xiao Wang, Ruiqi Liu, Shuang Li, Wenjie Xia, Haiwei Guo, Weiping Yao, Xiaodong Liang, Yanwei Lu, Haibo Zhang

    Résumé Résumé Plan Plan  
  • ·Regulation of protein prenylation

    Article :114915

    Dominik Jung, Hagen S. Bachmann

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  • ·Stem cell-derived exosomal MicroRNAs: Potential therapies in diabetic kidney disease

    Article :114961

    Han Wang, Jiajia Wang, Tiejun Liu, Yan Leng, Weipeng Yang

    Résumé Résumé Plan Plan  
  • ·Advances in dendritic cell vaccination therapy of cancer

    Article :114954

    Sajad Najafi, Keywan Mortezaee

    Résumé Résumé Plan Plan  
  • ·Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease

    Article :114950

    Botong Li, Yixuan Wang, Xiaolin Jiang, Hongwei Du, Yan Shi, Minghui Xiu, Yongqi Liu, Jianzheng He

    Résumé Résumé Plan Plan  
  • ·Cellular and molecular biology of sirtuins in cardiovascular disease

    Article :114931

    Yong-Ping Liu, Ri Wen, Chun-Feng Liu, Tie-Ning Zhang, Ni Yang

    Résumé Résumé Plan Plan  
  • ·P2Y12 receptor involved in the development of chronic nociceptive pain as a sensory information mediator

    Article :114975

    Wen-jun Zhang, Mei-yong Li, Cheng-yi Wang, Xiao Feng, Dong-xia Hu, Li-dong Wu, Jia-ling Hu

    Résumé Résumé Plan Plan  
  • ·Review deciphering potent therapeutic approaches targeting Notch signaling pathway in breast cancer

    Article :114938

    Pratibha Pandey, Fahad Khan, Min Choi, Sujeet Kumar Singh, Han Na Kang, Moon Nyeo Park, Seong-Gyu Ko, Sanjeev Kumar Sahu, Rupa Mazumder, Bonglee Kim

    Résumé Résumé Plan Plan  
  • ·Role of m6A modification in immune microenvironment of digestive system tumors

    Article :114953

    Chao Li, Mengqi Zhu, Jiajia Wang, Hengshuang Wu, Yameng Liu, Di Huang

    Résumé Résumé Plan Plan  
  • ·Biofilm modifiers: The disparity in paradigm of oral biofilm ecosystem

    Article :114966

    Antarikshya Das, Swadheena Patro, Faizan Zarreen Simnani, Dibyangshee Singh, Adrija Sinha, Khushbu Kumari, Patnala Vedika Rao, Sarita Singh, Nagendra Kumar Kaushik, Pritam Kumar Panda, Mrutyunjay Suar, Suresh K. Verma

    Résumé Résumé Plan Plan  
  • ·Challenges and opportunities for improving the druggability of natural product: Why need drug delivery system?

    Article :114955

    Peng Tang, Tianze Shen, Hairong Wang, Ruihan Zhang, Xingjie Zhang, Xiaoli Li, Weilie Xiao

    Résumé Résumé Plan Plan  
  • ·Reshaping immunometabolism in the tumour microenvironment to improve cancer immunotherapy

    Article :114963

    Shuchen Chen, He Duan, Gongping Sun

    Résumé Résumé Plan Plan  
  • ·Celastrol functions as an emerging manager of lipid metabolism: Mechanism and therapeutic potential

    Article :114981

    Jia Gu, Ya-Ning Shi, Neng Zhu, Hong-Fang Li, Chan-Juan Zhang, Li Qin

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  • ·Lactoferrin: Antimicrobial impacts, genomic guardian, therapeutic uses and clinical significance for humans and animals

    Article :114967

    Mohamed E. Abd El-Hack, Sameh A. Abdelnour, Mahmoud Kamal, Asmaa F. Khafaga, Afnan M. Shakoori, Rehab M. Bagadood, Hind M. Naffadi, Areej Y. Alyahyawi, Hanan Khojah, Saleh Alghamdi, Mariusz Jaremko, Sylwester Świątkiewicz

    Résumé Résumé Plan Plan  
  • ·Chronic inflammatory demyelinating polyradiculoneuropathy in patients with diabetes mellitus - treatment with intravenous immunoglobulins: A systematic review

    Article :114974

    Szymon Andrusiów, Zuzanna Pawlak, Bartłomiej Stańczykiewicz, Katarzyna Bogunia-Kubik, Magdalena Koszewicz

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  • ·Research progress on the role of PDGF/PDGFR in type 2 diabetes

    Article :114983

    Zhanqi Cao, Yijie Liu, Yini Wang, Ping Leng

    Résumé Résumé Plan Plan  
  • ·Gut microbiota and metabolites in diabetic retinopathy: Insights into pathogenesis for novel therapeutic strategies

    Article :114994

    Yue Cai, Yongbo Kang

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  • ·Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases

    Article :114993

    Ying Liu, Wei Ding, Jianxun Wang, Xiang Ao, Junqiang Xue

    Résumé Résumé Plan Plan  
  • ·The great potential of flavonoids as candidate drugs for NAFLD

    Article :114991

    Liangge Li, Yiming Qin, Xijian Xin, Shendong Wang, Zhaojun Liu, Xiujing Feng

    Résumé Résumé Plan Plan  
  • ·Current research status of anti-cancer peptides: Mechanism of action, production, and clinical applications

    Article :114996

    Raj Kumar Chinnadurai, Nazam Khan, Gautam Kumar Meghwanshi, Saravanaraman Ponne, Maryam Althobiti, Rajender Kumar

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  • ·Immunological mechanisms of inflammatory diseases caused by gut microbiota dysbiosis: A review

    Article :114985

    Min’an Zhao, Jiayi Chu, Shiyao Feng, Chuanhao Guo, Baigong Xue, Kan He, Lisha Li

    Résumé Résumé Plan Plan  
  • ·Cardiovascular disease treatment using traditional Chinese medicine：Mitochondria as the Achilles' heel

    Article :114999

    Jie Gao, Tianshu Hou

    Résumé Résumé Plan Plan  
  • ·Oxidative stress and metabolic syndrome in acne vulgaris: Pathogenetic connections and potential role of dietary supplements and phytochemicals

    Article :115003

    Alexa Florina Bungau, Andrei Flavius Radu, Simona Gabriela Bungau, Cosmin Mihai Vesa, Delia Mirela Tit, Laura Maria Endres

    Résumé Résumé Plan Plan  
  • ·Non-coding RNAs in renal cell carcinoma: Implications for drug resistance

    Article :115001

    Yiqi Liu, Hu Zhang, Yuan Fang, Dongshan Tang, Zhigang Luo

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  • ·Naringenin: A flavanone with anti-inflammatory and anti-infective properties

    Article :114990

    Ji Cai, Hongli Wen, He Zhou, Dan Zhang, Dongfeng Lan, Songpo Liu, Chunyang Li, Xiaofang Dai, Tao Song, Xianyao Wang, Yuqi He, Zhixu He, Jun Tan, Jidong Zhang

    Résumé Résumé Plan Plan  
  • ·Comparison of pharmacological activity and safety of different stereochemical configurations of borneol: L-borneol, D-borneol, and synthetic borneol

    Article :114668

    Rong Ma, Danni Lu, Jian Wang, Qian Xie, Jialiang Guo

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  • ·Coronary microvascular dysfunction and cardiovascular disease: Pathogenesis, associations and treatment strategies

    Article :115011

    Zhihua Yang, Yangxi Liu, Zhenzhen Li, Shaoling Feng, Shanshan Lin, Zhao Ge, Yujian Fan, Yi Wang, Xianliang Wang, Jingyuan Mao

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  • ·Evaluation of the association of chronic inflammation and cancer: Insights and implications

    Article :115015

    Manisha Nigam, Abhay Prakash Mishra, Vishal Kumar Deb, Deen Bandhu Dimri, Vinod Tiwari, Simona Gabriela Bungau, Alexa Florina Bungau, Andrei-Flavius Radu

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• Original Articles

  • ·Experimental study of ¹³¹I-caerin 1.1 and ¹³¹I-c(RGD)₂ for internal radiation therapy of esophageal cancer xenografts

    Article :114891

    Tiantian He, Juan Du, Keke Zhu, Yixuan Zhou, Zewei Xiao, Wenjie Liu, Weiwei Ren, Xiongying Liu, Tongsheng Chen, Wenjuan Liu, Zhuanming Chen, Guoying Ni, Xiaosong Liu, Tianfang Wang, Jiangtao Quan, Peipei Zhang, Jianwei Yuan

    Résumé Résumé Plan Plan  
  • ·Enzymatic preparation of chondroitin sulfate oligosaccharides and its alleviating effect on ovariectomy-induced osteoporosis in rats

    Article :114894

    Wei Zhang, Jikang Han, Zhiwen Jiang, Yanfei Peng, Xiaorui Sun, Baoqin Han

    Résumé Résumé Plan Plan  
  • ·Oral delivery of a highly stable superoxide dismutase as a skin aging inhibitor

    Article :114878

    Liang Dong, Yongli Chen, Lihong Gu, Miao Gan, Andrew Carrier, Ken Oakes, Xu Zhang, Zhiyang Dong

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  • ·Guiqi Baizhu prescription ameliorates cytarabine-induced intestinal mucositis by targeting JAK2 to inhibit M1 macrophage polarization

    Article :114902

    Wei Chu, Ya-ling Li, Jun-jie Li, Jia Lin, Mi Li, Jiao Wang, Jian-zheng He, Yue-mei Zhang, Juan Yao, Xiao-jie Jin, Hui Cai, Yong-qi Liu

    Résumé Résumé Plan Plan   
  • ·A carrier-free nano-drug assembled via π–π stacking interaction for the treatment of osteoarthritis

    Article :114881

    Wanwu Dai, Pan Jin, Xingyan Li, Jinmin Zhao, Ying Lan, Hongmian Li, Li Zheng

    Résumé Résumé Plan Plan  
  • ·Multi-target withaferin-A analogues as promising anti-kinetoplastid agents through the programmed cell death

    Article :114879

    Desirée San Nicolás-Hernández, Eduardo Hernández-Álvarez, Carlos J. Bethencourt-Estrella, Atteneri López-Arencibia, Ines Sifaoui, Isabel L. Bazzocchi, Jacob Lorenzo-Morales, Ignacio A. Jiménez, José E. Piñero

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  • ·Do immune checkpoint inhibitors share the same pharmacological feature in the risk of cardiac arrhythmias?

    Article :114912

    Annamaria Mascolo, Liberata Sportiello, Concetta Rafaniello, Maria Donniacuo, Donatella Ruggiero, Lucia Scisciola, Michelangela Barbieri, Francesco Rossi, Giuseppe Paolisso, Annalisa Capuano

    Résumé Résumé Plan Plan   
  • ·Ganetespib (STA-9090) augments sorafenib efficacy via necroptosis induction in hepatocellular carcinoma: Implications from preclinical data for a novel therapeutic approach

    Article :114918

    Sameh Saber, Alexandru Madalin Hasan, Osama A. Mohammed, Lobna A. Saleh, Abdullah A. Hashish, Mohannad Mohammad S. Alamri, Ahmed Y. Al-Ameer, Jaber Alfaifi, Ahmed Senbel, Adel Mohamed Aboregela, Tarig Babikir Algak Khalid, Mustafa Ahmed Abdel-Reheim, Simona Cavalu

    Résumé Résumé Plan Plan  
  • ·Predictive plasma biomarkers of long-term increase in hepatic steatosis index after HCV eradication in HIV/HCV-coinfected patients

    Article :114913

    Rubén Martín-Escolano, Ana Virseda-Berdices, Juan Berenguer, Juan González-García, Oscar Brochado-Kith, Amanda Fernández-Rodríguez, Cristina Díez, Victor Hontañon, Salvador Resino, María Ángeles Jiménez-Sousa, the GeSIDA 10318 Study Group

    Résumé Résumé Plan Plan   
  • ·Ginsenoside Rg1 ameliorates hypoxia-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition and inflammation by regulating CCN1

    Article :114920

    Bai-lin Tang, Yu Liu, Jing-liang Zhang, Mei-li Lu, Hong-xin Wang

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  • ·Therapeutic effects of methimazole on 3,4-methylenedioxymethamphetamine-induced hyperthermia and serotonergic neurotoxicity

    Article :114880

    I-Hsun Li, Tsung-Ta Liu, Ying-Chen Chen, Sheng-Huang Hsiao, Hao-Yuan Hung, Li-Yun Fann, Jui-Hu Shih

    Résumé Résumé Plan Plan  
  • ·Molecular mechanisms underlying the clinical efficacy of panobinostat involve Stochasticity of epigenetic signaling, sensitization to anticancer drugs, and induction of cellular cell death related to cellular stresses

    Article :114886

    Nasreddine El Omari, Saad Bakrim, Asaad Khalid, Ashraf N. Abdalla, Waleed Hassan Almalki, Learn-Han Lee, Chrismawan Ardianto, Long Chiau Ming, Abdelhakim Bouyahya

    Résumé Résumé Plan Plan  
  • ·Metabolic heterogeneity in TNBCs: A potential determinant of therapeutic efficacy of 2-deoxyglucose and metformin combinatory therapy

    Article :114911

    Samson Mathews Samuel, Elizabeth Varghese, Noothan Jyothi Satheesh, Chris R. Triggle, Dietrich Büsselberg

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  • ·Chiral 2-azabicycloalkanes bearing 1,2,3-triazole, thiourea, and ebselen moieties – Synthesis and biological activity

    Article :114908

    Franz Steppeler, Dominika Iwan, Radosław Gaida, Marta Denel-Bobrowska, Agnieszka B. Olejniczak, Elżbieta Wojaczyńska

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  • ·Fluorofenidone protects against acute liver failure in mice by regulating MKK4/JNK pathway

    Article :114844

    Lei Gu, Xin He, Yanqiu Zhang, Shenglan Li, Jie Tang, Ruixue Ma, Xinyi Yang, Hao Huang, Yu Peng, Yanyun Xie, Zhangzhe Peng, Jie Meng, Gaoyun Hu, Lijian Tao, Xiaowei Liu, Huixiang Yang

    Résumé Résumé Plan Plan   
  • ·Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.

    Article :114897

    Zijun Liu, Ping Nan, Yihui Gong, Ling Tian, Yin Zheng, Zhongming Wu

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  • ·Lithium treatment mitigates the diabetogenic effects of chronic cortico-therapy

    Article :114895

    Etienne Delangre, Gaëlle Pommier, Stefania Tolu, Benjamin Uzan, Danielle Bailbé, Jamileh Movassat

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  • ·Novel treatment and insight for irradiation-induced injuries: Dibucaine ameliorates irradiation-induced testicular injury by inhibiting fatty acid oxidation in primary Leydig cells

    Article :114903

    Lingxiang Ran, Qiu Chen, Xingyu Lu, Zhixiang Gao, Fengmei Cui, Xiaolong Liu, Boxin Xue

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  • ·Effects of 20-hydroxyecdysone on UVB-induced photoaging in hairless mice

    Article :114899

    Hye-Sun Lim, Kyeongno Yoon, Dong Hun Lee, Yong-Seok Lee, Jin Ho Chung, Gunhyuk Park

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  • ·Unfavorable effects of memantine on the skeletal system in female rats

    Article :114921

    Piotr Londzin, Urszula Cegieła, Marcin Trawczyński, Zenon P. Czuba, Joanna Folwarczna

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  • ·Royal jelly mediates fibrotic signaling, collagen cross-linking and cell proliferation in cardiac fibroblasts

    Article :114922

    Doa’a G.F. Al-U’datt, Muhammad H. Alu’datt, Carole C. Tranchant, Ahmed Al-Dwairi, Othman Al-shboul, Ali Almajwal, Lina Elsalem, Saied Jaradat, Karem H. Alzoubi, Belal G. Faleh, Yaman B. Ahmed, Jenan Alqbelat

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  • ·Huoluo Xiaoling Pellet promotes microglia M2 polarization through increasing MCPIP1 expression for ischemia stroke alleviation

    Article :114914

    Wei Shen, Xiaoguang Wang, Meiqi Tang, Lan Yao, Chenyu Wan, Jianli Niu, Pappachan E. Kolattukudy, Zhuqing Jin

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  • ·p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis

    Article :114925

    Zehua Ye, Yuqi Xia, Lei Li, Bojun Li, Lijia Chen, Weimin Yu, Yuan Ruan, Ting Rao, Xiangjun Zhou, Fan Cheng

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  • ·Vitamin A metabolites inhibit ferroptosis

    Article :114930

    Md. Jakaria, Abdel A. Belaidi, Ashley I. Bush, Scott Ayton

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  • ·Pharmacological insights emerging from the characterization of a large collection of synthetic cannabinoid receptor agonists designer drugs

    Article :114934

    Claudia Gioé-Gallo, Sandra Ortigueira, José Brea, Iu Raïch, Jhonny Azuaje, M. Rita Paleo, Maria Majellaro, María Isabel Loza, Cristian O. Salas, Xerardo García-Mera, Gemma Navarro, Eddy Sotelo

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  • ·Betanin improves motor function and alleviates experimental Parkinsonism via downregulation of TLR4/MyD88/NF-κB pathway: Molecular docking and biological investigations

    Article :114917

    Mohamed H. ElSayed, Huda M. Atif, Mohamed Ahmed Eladl, Samah M. Elaidy, Ahmed M.N. Helaly, Fatma Azzahraa Hisham, Noha E. Farag, Noura M.S. Osman, Afaf T. Ibrahiem, Heba W.Z. Khella, Shymaa E. Bilasy, Marzough Aziz Albalawi, Mohamed A. Helal, Wafa Ali Alzlaiq, Sawsan A. Zaitone

    Résumé Résumé Plan Plan  
  • ·Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet

    Article :114926

    Eui Kyung Youn, Hyun Min Cho, Jin Ki Jung, Ga-Eun Yoon, Masumi Eto, Jee In Kim

    Résumé Résumé Plan Plan   
  • ·In-depth in-vitro and in-vivo anti-diabetic evaluations of Fagonia cretica mediated biosynthesized selenium nanoparticles

    Article :114872

    Haider Ali Khan, Mehreen Ghufran, Sulaiman Shams, Alam Jamal, Muhammad Ayaz, Mehran Ullah, Abbas Khan, Mohammad Imran Khan, Zuhier A. Awan

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  • ·Targeting calcium signaling by inositol trisphosphate receptors: A novel mechanism for the anti-asthmatic effects of Houttuynia cordata

    Article :114935

    Alexis Shiying Huang, Benjamin Chun-Kit Tong, Harry Chun-Hin Hung, Aston Jiaxi Wu, Olivia Ka-Yi Ho, Anna Hau-Yee Kong, Maggie Ming-Ki Leung, Jingxuan Bai, Xiuqiong Fu, Zhiling Yu, Min Li, Ting Fan Leung, Judith Choi-Wo Mak, George Pak-Heng Leung, King-Ho Cheung

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  • ·Areca catechu L. ameliorates chronic unpredictable mild stress-induced depression behavior in rats by the promotion of the BDNF signaling pathway

    Article :114459

    Caihong Yao, Yiwen Zhang, Xinran Sun, Haiyue Pei, Shanshan Wei, Mengdi Wang, Qi Chang, Xinmin Liu, Ning Jiang

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  • ·Canagliflozin mitigates carfilzomib-induced endothelial apoptosis via an AMPK-dependent pathway

    Article :114907

    Mohamed S. Dabour, Ibrahim Y. Abdelgawad, Marianne K.O. Grant, Engie S. El-Sawaf, Beshay N. Zordoky

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  • ·Relief of ovalbumin-induced airway remodeling by the glycyl-l-histidyl-l-lysine-Cu²⁺ tripeptide complex via activation of SIRT1 in airway epithelial cells

    Article :114936

    Qin Zhang, Jia Liu, Ming-ming Deng, Run Tong, Gang Hou

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  • ·Gene expression profiling in white blood cells reveals new insights into the molecular mechanisms of thalidomide in children with inflammatory bowel disease

    Article :114927

    Letizia Pugnetti, Debora Curci, Carlotta Bidoli, Marco Gerdol, Fulvio Celsi, Sara Renzo, Monica Paci, Sara Lega, Martina Nonnis, Alessandra Maestro, Liza Vecchi Brumatti, Paolo Lionetti, Alberto Pallavicini, Danilo Licastro, Paolo Edomi, Giuliana Decorti, Gabriele Stocco, Marianna Lucafò, Matteo Bramuzzo

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  • ·An extensive pharmacological evaluation of novel anti-nociceptive and IL-6 targeted anti-inflammatory guaiane-type sesquiterpenoids from Cinnamomum migao H. W. Li through in-depth in-vitro, ADMET, and molecular docking studies

    Article :114946

    Ishaq Muhammad, Syed Shams ul Hassan, Wen-Jing Xu, Guo-Li Tu, Hua-Jun Yu, Xue Xiao, Shi-Kai Yan, Hui-Zi Jin, Simona Bungau

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  • ·Elucidation of scandenolone as anti-cancer activity through impairment of the metabolic and signaling vulnerabilities in prostate cancer

    Article :114948

    Praveenkumar Basavaraj, Po-Fan Hsieh, Wen-Ping Jiang, Da-Tian Bau, Guan-Jhong Huang, Wen-Chin Huang

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  • ·Metformin protects fibroblasts from patients with GNE myopathy by restoring autophagic flux via an AMPK/mTOR-independent pathway

    Article :114958

    Tongtong Zhang, Xiang Yin, Xuefan Yu, Ren Shang, Liuzhe Lu, Jing Miao

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  • ·Photoacoustic imaging-guided triple-responsive nanoparticles with tumor hypoxia relief for improving chemotherapy/ photothermal/photodynamic synergistic therapy against breast cancer

    Article :114928

    Changxiang Yu, Lihui Kong, Juan Tian, Ying Zhang, Xintao Jia, Wenli Dang, Bin Xing, Qingqing Zhang, Xiaochen Pang, Zheming Hu, Bei Jia, Jiachen He, Zhi-Ming Zhang, Zhidong Liu

    Résumé Résumé Plan Plan   
  • ·Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders

    Article :114945

    Laetitia Dore, Erwann Durand, Béatrice Bonafos, Jatuporn Chaiyut, Laurent Vaysse, Siriluck Liengprayoon, Sylvie Gaillet, Laurence Pessemesse, Karen Lambert, Christelle Bertrand-Gaday, Charles Coudray, Ariane Sultan, François Casas, Christine Feillet-Coudray

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  • ·Phytochemical analysis and evaluation of antimicrobial, antioxidant, and antidiabetic activities of essential oils from Moroccan medicinal plants: Mentha suaveolens, Lavandula stoechas, and Ammi visnaga

    Article :114937

    Naoufal El Hachlafi, Nesrine Benkhaira, Samiah Hamad Al-Mijalli, Hanae Naceiri Mrabti, Rhizlan Abdnim, Emad M. Abdallah, Mohamed Jeddi, Mohamed Bnouham, Learn-Han Lee, Chrismawan Ardianto, Long Chiau Ming, Abdelhakim Bouyahya, Kawtar Fikri-Benbrahim

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  • ·Bergapten ameliorates combined allergic rhinitis and asthma syndrome after PM2.5 exposure by balancing Treg/Th17 expression and suppressing STAT3 and MAPK activation in a mouse model

    Article :114959

    Yuna Jiang, Thi Van Nguyen, Juan Jin, Zhen Nan Yu, Chang Ho Song, Ok Hee Chai

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  • ·Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development

    Article :114956

    Changpei Gan, Jing Wang, Yaogeng Wang, Alejandra Martínez-Chávez, Michel Hillebrand, Niels de Vries, Joke Beukers, Maria C. Lebre, Els Wagenaar, Hilde Rosing, Sjoerd Klarenbeek, Onno B. Bleijerveld, Ji-Ying Song, Maarten Altelaar, Jos H. Beijnen, Alfred H. Schinkel

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  • ·Pro-neurogenic effects of Lilii Bulbus on hippocampal neurogenesis and memory

    Article :114951

    Hee Ra Park, Heeeun Lee, Won-Kyung Cho, Jin Yeul Ma

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  • ·Chitosan-decorated and tripolyphosphate-crosslinked pH-sensitive niosomal nanogels for Controlled release of fluoropyrimidine 5-fluorouracil

    Article :114943

    Mohammed Mahmood Ahmed, Muath Sheet Mohammed Ameen, Morteza Abazari, Safa Momeni Badeleh, Kobra Rostamizadeh, Shahen Salih Mohammed

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  • ·Synergistic effect of Ru(II)-based type II photodynamic therapy with cefotaxime on clinical isolates of ESBL-producing Klebsiella pneumoniae

    Article :114949

    Dafne Berenice Hormazábal, Ángeles Beatriz Reyes, Francisco Castro, Alan R. Cabrera, Paulina Dreyse, Felipe Melo-González, Susan M. Bueno, Iván A. González, Christian Erick Palavecino

    Résumé Résumé Plan Plan  
  • ·Dual amylin and calcitonin receptor agonist treatment improves insulin sensitivity and increases muscle-specific glucose uptake independent of weight loss

    Article :114969

    Anna Thorsø Larsen, Simone A. Melander, Nina Sonne, Emma Bredtoft, Mays Al-Rubai, Morten A. Karsdal, Kim Henriksen

    Résumé Résumé Plan Plan   
  • ·Secoisolariciresinol diglucoside Ameliorates Osteoarthritis via Nuclear factor-erythroid 2-related factor-2/ nuclear factor kappa B Pathway: In vitro and in vivo experiments

    Article :114964

    Zhiwei Zhang, Song Wang, Xuqiang Liu, Yuxin Yang, Yiqin Zhang, Bo Li, Fengfen Guo, Jianhui Liang, Xin Hong, Runsheng Guo, Bin Zhang

    Résumé Résumé Plan Plan   
  • ·Zearalenone attenuates colitis associated colorectal tumorigenesis through Ras/Raf/ERK pathway suppression and SCFA-producing bacteria promotion

    Article :114973

    Hoi Kit Matthew Leung, Emily Kwun Kwan Lo, Congjia Chen, Fangfei Zhang, Marsena Jasiel Ismaiah, Hani El-Nezami

    Résumé Résumé Plan Plan   
  • ·Ganoderenic acid D-loaded functionalized graphene oxide-based carrier for active targeting therapy of cervical carcinoma

    Article :114947

    Jiahui Lu, Anqiang Zhang, Fuming Zhang, Robert J. Linhardt, Zhihui Zhu, Yanzi Yang, Tinghuang Zhang, Zhibin Lin, Su Zhang, Huajun Zhao, Peilong Sun

    Résumé Résumé Plan Plan   
  • ·1,8-Cineole ameliorates diabetic retinopathy by inhibiting retinal pigment epithelium ferroptosis via PPAR-γ/TXNIP pathways

    Article :114978

    Zhangnian Liu, Shiquan Gan, Lingyun Fu, Yini Xu, Shengquan Wang, Guangqiong Zhang, Di Pan, Ling Tao, Xiangchun Shen

    Résumé Résumé Plan Plan   
  • ·Not all benzimidazole derivatives are microtubule destabilizing agents

    Article :114977

    In-ho Song, Su Jeong Park, Gyu Seong Yeom, Keum-soo Song, Taisun Kim, Satish Balasaheb Nimse

    Résumé Résumé Plan Plan   
  • ·Lymphocyte infiltration and antitumoral effect promoted by cytotoxic inflammatory proteins formulated as self-assembling, protein-only nanoparticles

    Article :114976

    Carlos Martínez-Torró, Lorena Alba-Castellón, Luis Miguel Carrasco-Díaz, Naroa Serna, Laura Imedio, Alberto Gallardo, Isolda Casanova, Ugutz Unzueta, Esther Vázquez, Ramón Mangues, Antonio Villaverde

    Résumé Résumé Plan Plan  
  • ·Fluoxetine inactivates STAT3/NF-κB signaling and promotes sensitivity to cisplatin in bladder cancer

    Article :114962

    Che-Jui Yang, Zhao-Lin Tan, Jr-Di Yang, Fei-Ting Hsu, Chih-Hung Chiang

    Résumé Résumé Plan Plan   
  • ·Azithromycin induces read-through of the nonsense Apc allele and prevents intestinal tumorigenesis in C3B6F1 Apc^Min/+ mice

    Article :114968

    Ryoko Semba, Takamitsu Morioka, Hiromi Yanagihara, Kenshi Suzuki, Hirotaka Tachibana, Takahiro Hamoya, Yoshiya Horimoto, Tatsuhiko Imaoka, Mitsue Saito, Shizuko Kakinuma, Masami Arai

    Résumé Résumé Plan Plan   
  • ·Sanghuangporus vaninii ethanol extract alleviates hyperuricemic renal injury by regulating the uric acid transporters and inhibiting HK-2 apoptosis

    Article :114970

    Liping Hua, Shuangshuang Zhang, Jiali Yang, Xiaoqi Zhou, Senlin Shi

    Résumé Résumé Plan Plan   
  • ·Pleiotropic effects of Salacia reticulata and Simvastatin on oxidative stress and insulin resistance in a rat model

    Article :114960

    Sudhakara Gujjala, Manjunatha Bangeppagari, Venkata Lakshmi Narasimha Prasad Devarakonda, Ramesh Bellamkonda, Ramu Bhadramraju, Srinivasan Kameswaran, Rajendran Ramaswamy, Saralakumari Desireddy

    Résumé Résumé Plan Plan  
  • ·Clinical impact of body mass index on palbociclib treatment outcomes and effect on exposure

    Article :114906

    Rossana Roncato, Elena Peruzzi, Lorenzo Gerratana, Bianca Posocco, Sofia Nuzzo, Marcella Montico, Marco Orleni, Serena Corsetti, Michele Bartoletti, Sara Gagno, Giovanni Canil, Elena De Mattia, Jacopo Angelini, Massimo Baraldo, Fabio Puglisi, Erika Cecchin, Giuseppe Toffoli

    Résumé Résumé Plan Plan  
  • ·Hepatoprotective effect of Typhaneoside on non-alcoholic fatty liver disease via farnesoid X receptor in vivo and in vitro

    Article :114957

    Yi Zheng, Jian Zhao, Deyu Miao, Tingting Xu, Liziniu Wang, Changhui Liu, Yong Gao, Lili Yu, Chuangpeng Shen

    Résumé Résumé Plan Plan   
  • ·The novel K_V7 channel activator URO-K10 exerts enhanced pulmonary vascular effects independent of the KCNE4 regulatory subunit

    Article :114952

    Marta Villegas-Esguevillas, Suhan Cho, Alba Vera-Zambrano, Jae Won Kwon, Bianca Barreira, Göcken Telli, Jorge Navarro-Dorado, Daniel Morales-Cano, Beatriz de Olaiz, Laura Moreno, Iain Greenwood, Francisco Pérez-Vizcaíno, Sung Joon Kim, Belén Climent, Angel Cogolludo

    Résumé Résumé Plan Plan   
  • ·Dual targeting of Mg/N doped-carbon quantum dots with folic and hyaluronic acid for targeted drug delivery and cell imaging

    Article :114971

    Nasrin Ziaee, Nafiseh Farhadian, Khalil Abnous, Maryam M. Matin, Ali Khoshnood, Elnaz Yaghoobi

    Résumé Résumé Plan Plan  
  • ·Protective effect of the novel cyclic peptide ASK0912 on mice with sepsis induced by Acinetobacter baumannii

    Article :114965

    Chunyang Xie, Penghe Wang, Huige Wu, Xinxin Hu, Tongying Nie, Xue Li, Pengbo Pang, Guoqing Li, Yun Lu, Xinyi Yang, Xiukun Wang, Congran Li, Xuefu You

    Résumé Résumé Plan Plan   
  • ·Baicalin enhances the efficacy of 5-Fluorouracil in gastric cancer by promoting ROS-mediated ferroptosis

    Article :114986

    Jingwen Yuan, Shahid Ullah Khan, Junfeng Yan, Jiatong Lu, Chen Yang, Qiang Tong

    Résumé Résumé Plan Plan   
  • ·Cinchonine exerts anti-tumor and immunotherapy sensitizing effects in lung cancer by impairing autophagic-lysosomal degradation

    Article :114980

    Huan Wang, Yuting Shi, Dannv Ma, Mengqing Cao, Yuchao Sun, Xinyuan Jiang, Zhiyong Xu, Yongfang Wang, Ying Yang, Yueli Shi, Kai Wang

    Résumé Résumé Plan Plan   
  • ·Molecular mechanisms of the tyrosine kinase inhibitor pralsetinib activity in in-vitro models of medullary thyroid carcinoma: Aberrant activation of the HH-Gli signaling pathway in acquired resistance

    Article :114995

    Sofia Trocchianesi, Agnese Po, Anna Citarella, Zaira Spinello, Aurelia Rughetti, Zein Mersini Besharat, Tanja Milena Autilio, Valeria Pecce, Antonella Verrienti, Rossella Elisei, Cosimo Durante, Giuseppina Catanzaro, Elisabetta Ferretti

    Résumé Résumé Plan Plan   
  • ·Optimization of human skin keratinocyte culture protocols using bioactive molecules derived from olive oil

    Article :115000

    Olimpia Ortiz-Arrabal, Fabiola Bermejo-Casares, Ingrid Garzón, María-Dolores Mesa-García, Carolina Gómez-Llorente, Miguel Alaminos

    Résumé Résumé Plan Plan   
  • ·Alcohol perturbed locomotor behavior, metabolism, and pharmacokinetics of gamma-hydroxybutyric acid in rats

    Article :114992

    Mingyu Kim, Songjin Oh, Suji Kim, Moongi Ji, Byeongchan Choi, Jung-Woo Bae, Yong Sup Lee, Man-Jeong Paik, Sooyeun Lee

    Résumé Résumé Plan Plan   
  • ·Anti-photoaging effect and mechanism of flexible liposomes co-loaded with apigenin and doxycycline

    Article :114998

    Chang Liu, Xiao Guo, Yutong Chen, Meijun Zhao, Shuai Shi, Zheng Luo, Jian Song, Zhihong Zhang, Wenchuang Yang, Keyi Liu

    Résumé Résumé Plan Plan  
  • ·The Chinese herbal medicine Fufang Zhenzhu Tiaozhi ameliorates diabetic cardiomyopathy by regulating cardiac abnormal lipid metabolism and mitochondrial dynamics in diabetic mice

    Article :114919

    Meiling Yan, Suping Liu, Wenru Zeng, Qiaoling Guo, Yu Mei, Xiaoqi Shao, Liyan Su, Zhou Liu, Yue Zhang, Lexun Wang, Hongtao Diao, Xianglu Rong, Jiao Guo

    Résumé Résumé Plan Plan   
  • ·Zinc oxide nanoparticles induce toxicity in diffuse large B-cell lymphoma cell line U2932 via activating PINK1/Parkin-mediated mitophagy.

    Article :114988

    Zonghong Li, Xuewei Yin, Chunyi Lyu, Teng Wang, Wenhao Wang, Jiachen Zhang, Jinxin Wang, Zhenzhen Wang, Chen Han, Ruixue Zhang, Dadong Guo, Ruirong Xu

    Résumé Résumé Plan Plan  
  • ·Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT7519

    Article :115002

    Kaja Karaś, Iwona Karwaciak, Katarzyna Chałaśkiewicz, Anna Sałkowska, Joanna Pastwińska, Rafał A. Bachorz, Marcin Ratajewski

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  • ·β-Cyclodextrins as affordable antivirals to treat coronavirus infection

    Article :114997

    Dalia Raïch-Regué, Raquel Tenorio, Isabel Fernández de Castro, Ferran Tarrés-Freixas, Martin Sachse, Daniel Perez-Zsolt, Jordana Muñoz-Basagoiti, Sara Y. Fernández-Sánchez, Marçal Gallemí, Paula Ortega-González, Alberto Fernández-Oliva, José A. Gabaldón, Estrella Nuñez-Delicado, Josefina Casas, Núria Roca, Guillermo Cantero, Mónica Pérez, Carla Usai, Cristina Lorca-Oró, Júlia-Vergara Alert, Joaquim Segalés, Jorge Carrillo, Julià Blanco, Bonaventura Clotet Sala, José P. Cerón-Carrasco, Nuria Izquierdo-Useros, Cristina Risco

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  • ·Alternative pathway of bile acid biosynthesis contributes to ameliorate NASH after induction of NAMPT/NAD⁺/SIRT1 axis

    Article :114987

    Na Yang, Runbin Sun, Xiaoli Zhang, Jing Wang, Lulu Wang, Huaijun Zhu, Man Yuan, Yifan Xu, Chun Ge, Jun He, Min Wang

    Résumé Résumé Plan Plan   
  • ·Huangqi-Danshen decoction reshapes renal glucose metabolism profiles that delays chronic kidney disease progression

    Article :114989

    Xi Huang, Liwen Gao, Ruyu Deng, Yu Peng, Shanshan Wu, Jiandong Lu, Xinhui Liu

    Résumé Résumé Plan Plan   
  • ·Antileishmanial, cellular mechanisms, and cytotoxic effects of green synthesized zinc nanoparticles alone and in combined with glucantime against Leishmania major infection

    Article :114984

    Javad Ghasemian Yadegari, Amal Khudair Khalaf, Fatemeh Ezzatkhah, Mojtaba Shakibaie, Hamid Reza Mohammadi, Hossein Mahmoudvand

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  • ·Effects of CBD supplementation on ambulatory blood pressure and serum urotensin-II concentrations in Caucasian patients with essential hypertension: A sub-analysis of the HYPER-H21-4 trial

    Article :115016

    Marko Kumric, Goran Dujic, Josip Vrdoljak, Daniela Supe-Domic, Nada Bilopavlovic, Kresimir Dolic, Zeljko Dujic, Josko Bozic

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  • ·Quercus coccinea Münchh leaves polyphenols: Appraisal acute lung injury induced by lipopolysaccharide in mice

    Article :114765

    Elsayed K. El-Sayed, Reham R. Ibrahim, Asmaa A. Ahmed, Mohamed A. Khattab, Lo-Yun Chen, Kuei-Hung Lai, Fatheya S. El Shaarawy, Nashwa F. Tawfik, Fatma A. Moharram

    Résumé Résumé Plan Plan   

• Short Communications

  • ·Therapeutic effects of guanidine hydrochloride on breast cancer through targeting KCNG1 gene

    Article :114982

    Mehdi Roshanian Bakhsh, Leila Rouhi, Kamran Ghaedi, Mehrdad Hashemi, Maryam Peymani, Saeed Samarghandian

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• Letters to the Editor

  • ·Bmal1 and Gut-lung axis in SARS-CoV-2 infection: New insight into the effects of melatonin on COVID-19 patients?

    Article :114291

    Mohammad Rafi Khezri, Reza Varzandeh, Morteza Ghasemnejad-Berenji

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• Corrigendum

  • ·Corrigendum to “Antidiabetic and antioxidant activities of Mitragyna speciosa (kratom) leaf extract in type 2 diabetic rats” [Biomed. Pharmacother. 162 (2023) 114689]

    Article :114939

    Pengpeng Zhang, Wei Wei, Xiaohai Zhang, Chaoling Wen, Chitchamai Ovatlarnporn, Opeyemi Joshua Olatunji

     
  • ·Corrigendum to “Bone marrow mesenchymal stem cells alleviate the daunorubicin-induced subacute myocardial injury in rats through inhibiting infiltration of T lymphocytes and antigen-presenting cells” [Biomed. Pharmacother. 121 (2020) 109157]

    Article :114940

    Qiuru Chen, Yuxin Zhang, Haojie Zhu, Xiaohong Yuan, Xiaofeng Luo, Xueqiong Wu, Shaozhen Chen, Yongquan Chen, Jingjing Xu, Hajji Ally Issa, Zhihong Zheng, Jianda Hu, Ting Yang

     
  • ·Corrigendum to “Hyperprogression, a challenge of PD-1/PD-L1 inhibitors treatments: potential mechanisms and coping strategies” [Biomed. Pharmacother. 150 (2022) 112949]

    Article :114944

    Li-ping Zhao, Jun-hu Hu, Die Hu, Hao-jie Wang, Chang-gang Huang, Ru-hua Luo, Zhao-huang Zhou, Xin-yun Huang, Tian Xie, Jian-shu Lou

    
  • ·Corrigendum to “Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review” [ Biomed. Pharamacother. 133, (2021) 110968]

    Article :114979

    Zi-Ying Wang, Jia Liu, Zhou Zhu, Cheng-Fu Su, Sravan Gopalkrishnashetty Sreenivasmurthy, Ashok Iyaswamy, Jia-Hong Lu, Gang Chen, Ju-Xian Song, Min Li

    

• Retractions

  • ·Retraction notice to “The silencing of ApoC3 suppresses oxidative stress and inflammatory responses in placenta cells from mice with preeclampsia via inhibition of the NF-κB signaling pathway” [Biomed. Pharmacother. 107 (2018) 1377–1384]

    Article :114722

    Fa-Hong Li, Yong Wang, Xiao-Ling Liu, Qian Xu

    
  • ·Retraction notice to “MicroRNA-361-5p inhibits papillary thyroid carcinoma progression by targeting ROCK1” [Biomed. Pharmacother. 102 (2018) 988–995]

    Article :114723

    Rui Li, Bingfei Dong, Zhengmin Wang, Tao Jiang, Guang Chen

    
  • ·Retraction notice to “Down-regulation of microRNA-21 reduces inflammation and podocyte apoptosis in diabetic nephropathy by relieving the repression of TIMP3 expression” [Biomed. Pharmacother. 108 (2018) 7–14]

    Article :114725

    Xiaoping Chen, Lei Zhao, Yanwei Xing, Bo Lin

    
  • ·Retraction notice to “Repression of long non-coding RNA MEG3 restores nerve growth and alleviates neurological impairment after cerebral ischemia-reperfusion injury in a rat model” [Biomed. Pharmacother. 111 (2019) 1447–1457]

    Article :114726

    Dong You, Hong You

    
  • ·Retraction notice to “Up-regulation of microRNA-223 inhibits brain injury and hippocampal neuron apoptosis of rats after febrile seizure through the NLRP3-Caspase-1 signaling pathway” [Biomedi. Pharmacother. 114 (2019) 108683]

    Article :114727

    Bin Wang, Xiangke Cao, Jie Lin, Qingqiang Qian, Ling Yu, Qingzeng Qian

    
  • ·Retraction notice to “LNCRNA CDKN2B-AS1 regulates mesangial cell proliferation and extracellular matrix accumulation via miR-424-5p/HMGA2 axis” [Biomed. Pharmacother. 121 (2020) 109622]

    Article :114728

    Yang Li, Lin-Lin Zheng, Deng-Gao Huang, Hui Cao, Yuan-Hui Gao, Zhong-Cheng Fan

    
  • ·Retraction notice to “The effect of microRNA-328 antagomir on erectile dysfunction instreptozotocin-induced diabetic rats” [Biomed. Pharmacother. 92 (2017) 888–895]

    Article :114729

    Dong-Shui Li, Liang Feng, Long-Hua Luo, Zhi-Feng Duan, Xian-Long Li, Chun-Hua Yin, Xiang Sun

    
  • ·Retraction notice to "Protective effects of total flavonoids in caragana against hypoxia/reoxygenation-induced injury in human brain microvascular endothelial cells", [Biomed. Pharmacother. 89 (2017) 316–322]

    Article :114736

    Qian-Song He, Li Zhang, Zi-Yuan Fan, Guo Feng, Fu-Jiang Wang, Zheng-Qi Liu, Ting Tang, Shi-Xiang Kuang