Sommaire

• • ·Editorial Board

    Article :112968

    

• Review Articles

  • ·LINC00339: An emerging major player in cancer and metabolic diseases

    Article :112788

    Zeyu Wu, Shuijun Zhang, Wenzhi Guo, Yuting He

    Résumé Résumé Plan Plan  
  • ·Traditional Chinese medicine against COVID-19: Role of the gut microbiota

    Article :112787

    Zhihua Yang, Yangxi Liu, Lin Wang, Shanshan Lin, Xiangdong Dai, Haifeng Yan, Zhao Ge, Qiuan Ren, Hui Wang, Feng Zhu, Shuping Wang

    Résumé Résumé Plan Plan  
  • ·The multifaceted mechanisms of Paeoniflorin in the treatment of tumors: State-of-the-Art

    Article :112800

    Xue Zhen Wang, Lei Xia, Xiao Yu Zhang, Qian Chen, Xiao Li, Yue Mou, Tong Wang, Ya Nan Zhang

    Résumé Résumé Plan Plan  
  • ·Progress in traditional Chinese medicine and natural extracts for the treatment of lupus nephritis

    Article :112799

    Yu-Jiao Wang, Ya-Xin Li, Shuo Li, Wei He, Zi-Rui Wang, Tian-Peng Zhan, Chao-Yue Lv, Ying-Ping Liu, Yang Yang, Xiao-Xi Zeng

    Résumé Résumé Plan Plan  
  • ·Adipocytokines: Emerging therapeutic targets for pain management

    Article :112813

    Shao-Jie Gao, Dai-Qiang Liu, Dan-Yang Li, Jia Sun, Long-Qing Zhang, Jia-Yi Wu, Fan-He Song, Ya-Qun Zhou, Wei Mei

    Résumé Résumé Plan Plan  
  • ·LncRNA MNX1-AS1: A novel oncogenic propellant in cancers

    Article :112801

    Tengfei Li, Shuai Zhou, Yan Yang, Yanyan Xu, Xin Gong, Yunsheng Cheng, Yong Wang

    Résumé Résumé Plan Plan  
  • ·Traumatic brain injury and the development of parkinsonism: Understanding pathophysiology, animal models, and therapeutic targets

    Article :112812

    Smrithi Padmakumar, Praveen Kulkarni, Craig F. Ferris, Benjamin S. Bleier, Mansoor M. Amiji

    Résumé Résumé Plan Plan  
  • ·The comparison of dexketoprofen and other painkilling medications (review from 2018 to 2021)

    Article :112819

    Joanna Kuczyńska, Angelika Pawlak, Barbara Nieradko-Iwanicka

    Résumé Résumé Plan Plan  
  • ·Nitric oxide-releasing biomaterials for promoting wound healing in impaired diabetic wounds: State of the art and recent trends

    Article :112707

    Rashid Ahmed, Robin Augustine, Maryam Chaudhry, Usman A. Akhtar, Alap Ali Zahid, Muhammad Tariq, Mojtaba Falahati, Irfan S. Ahmad, Anwarul Hasan

    Résumé Résumé Plan Plan  
  • ·The Regulatory effect of chlorogenic acid on gut-brain function and its mechanism: A systematic review

    Article :112831

    Li Zeng, Rong Xiang, Chunyan Fu, Zhihao Qu, Changwei Liu

    Résumé Résumé Plan Plan  
  • ·Lymph node micrometastasis in non–small cell lung cancer

    Article :112817

    Jiajing Sun, Sikai Wu, Zixian Jin, Sijia Ren, William C. Cho, Chengchu Zhu, Jianfei Shen

    Résumé Résumé Plan Plan  
  • ·Potential molecular mechanisms and clinical progress in liver metastasis of breast cancer

    Article :112824

    Hanyuan Liu, Xiao Li, Haiyang Li, Lei Feng, Guangshun Sun, Guoqiang Sun, Liangliang Wu, Yun Hu, Li Liu, Hanjin Wang

    Résumé Résumé Plan Plan  
  • ·Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy

    Article :112827

    Meng-Lan Luo, Wei Huang, Hong-Ping Zhu, Cheng Peng, Qian Zhao, Bo Han

    Résumé Résumé Plan Plan  
  • ·Arginase: An emerging and promising therapeutic target for cancer treatment

    Article :112840

    Fanglin Niu, Yi Yu, Zhuozhuo Li, Yuanyuan Ren, Zi Li, Qiang Ye, Ping Liu, Chenshuang Ji, Lu Qian, Yuyan Xiong

    Résumé Résumé Plan Plan  
  • ·Gut microbiota-derived metabolites as key actors in type 2 diabetes mellitus

    Article :112839

    Leilei Du, Qi Li, Huan Yi, Tingting Kuang, Yi Tang, Gang Fan

    Résumé Résumé Plan Plan  
  • ·Tumor-derived exosomes: the emerging orchestrators in melanoma

    Article :112832

    Yufang Tan, Fang Tang, Jieming Li, Honghao Yu, Min Wu, Yiping Wu, Hong Zeng, Kai Hou, Qi Zhang

    Résumé Résumé Plan Plan  
  • ·Epidemiology, clinical ramifications, and cellular pathogenesis of COVID-19 mRNA-vaccination-induced adverse cardiovascular outcomes: A state-of-the-heart review

    Article :112843

    Talal Almas, Sarah Rehman, Eyad Mansour, Tarek Khedro, Ali Alansari, Jahanzeb Malik, Norah Alshareef, Vikneswaran Raj Nagarajan, Abdulla Hussain Al-Awaid, Reema Alsufyani, Majid Alsufyani, Ali Rifai, Ahlam Alzahrani, Dhineswaran Raj Nagarajan, Tala Abdullatif, Varman Gunasaegaram, Enaam Alzadjali, Arthi Subramanian, Abida Rahman, Yasar Sattar, Jason Galo, Hafeez Ul Hassan Virk, M. Chadi Alraies

    Résumé Résumé Plan Plan  
  • ·Complexation of phytochemicals with cyclodextrins and their derivatives- an update

    Article :112862

    Vasanti Suvarna, Bhunesh Bore, Chaitanya Bhawar, Rashmi Mallya

    Résumé Résumé Plan Plan  
  • ·Progress and perspective of organoid technology in cancer-related translational medicine

    Article :112869

    Yusheng Lin, Li Jiang, Qiaojun He, Meng Yuan, Ji Cao

    Résumé Résumé Plan Plan  
  • ·Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis

    Article :112896

    Mengsha Zou, Jinze Shen, Yuchen Wu, Chenming Zhong, Li Fang, Feng Zhu, Shiwei Duan

    Résumé Résumé Plan Plan  
  • ·Novel insights into the SPOP E3 ubiquitin ligase: From the regulation of molecular mechanisms to tumorigenesis

    Article :112882

    Xian-Miao Li, Huan-Lei Wu, Qi-Dong Xia, Peng Zhou, Shao-Gang Wang, Xiao Yu, Jia Hu

    Résumé Résumé Plan Plan  
  • ·Acupuncture for Parkinson’s disease: From theory to practice

    Article :112907

    Jing-Qi Fan, Wei-Jing Lu, Wei-Qiang Tan, Wei-Cheng Feng, Li-Xing Zhuang

    Résumé Résumé Plan Plan  
  • ·From ancient leech to direct thrombin inhibitors and beyond: New from old

    Article :112878

    Maria Rosa Montinari, Sergio Minelli

    Résumé Résumé Plan Plan  
  • ·Protective effects of natural products against myocardial ischemia/reperfusion: Mitochondria-targeted therapeutics

    Article :112893

    Xin Su, Mingyang Zhou, Yingjian Li, Jianzhen Zhang, Na An, Fan Yang, Guoxia Zhang, Chao Yuan, Hengwen Chen, Hongjin Wu, Yanwei Xing

    Résumé Résumé Plan Plan  
  • ·Mechanism of cell death pathways in status epilepticus and related therapeutic agents

    Article :112875

    Ke Du, Miao He, Dongyi Zhao, Yuting Wang, Chao Ma, Hongyue Liang, Wuyang Wang, Dongyu Min, Lei Xue, Feng Guo

    Résumé Résumé Plan Plan  
  • ·Exploring the journey of emodin as a potential neuroprotective agent: Novel therapeutic insights with molecular mechanism of action

    Article :112877

    Saikat Mitra, Juhaer Anjum, Maniza Muni, Rajib Das, Abdur Rauf, Fahadul Islam, Talha Bin Emran, Prabhakar Semwal, Hassan A. Hemeg, Fahad A. Alhumaydhi, Polrat Wilairatana

    Résumé Résumé Plan Plan  
  • ·Mitochondria-associated membranes: A hub for neurodegenerative diseases

    Article :112890

    Jinxuan Liu, Jinghua Yang

    Résumé Résumé Plan Plan  
  • ·The potential applications of traditional Chinese medicine in Parkinson's disease: A new opportunity

    Article :112866

    Jiaxue Chen, Jingke Xu, Ping Huang, Yining Luo, Yuanshu Shi, Ping Ma

    Résumé Résumé Plan Plan  
  • ·Development of vericiguat: The first soluble guanylate cyclase (sGC) stimulator launched for heart failure with reduced ejection fraction (HFrEF)

    Article :112894

    Juan Xia, Nan Hui, Lei Tian, Chengyuan Liang, Jie Zhang, Jifang Liu, Jun Wang, Xiaodong Ren, Xiaolin Xie, Kun Wang

    Résumé Résumé Plan Plan  
  • ·Endoplasmic reticulum stress in airway hyperresponsiveness

    Article :112904

    Qirui Duan, Ying Zhou, Dong Yang

    Résumé Résumé Plan Plan  
  • ·Microbiome in cancer: Role in carcinogenesis and impact in therapeutic strategies

    Article :112898

    Md. Mominur Rahman, Md. Rezaul Islam, Sheikh Shohag, Md. Tanjimul Ahasan, Nadia Sarkar, Hosneara Khan, Alexandru Madalin Hasan, Simona Cavalu, Abdur Rauf

    Résumé Résumé Plan Plan  
  • ·Hesperidin and hesperetin against heavy metal toxicity: Insight on the molecular mechanism of mitigation

    Article :112914

    Ademola C. Famurewa, Kaviyarasi Renu, Mohamed Ahmed Eladl, Rituraj Chakraborty, Haritha Myakala, Mohamed El-Sherbiny, Dalia Mahmoud Abdelmonem Elsherbini, Balachandar Vellingiri, Harishkumar Madhyastha, Uddesh Ramesh Wanjari, Anirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan

    Résumé Résumé Plan Plan  
  • ·Combined drug triads for synergic neuroprotection in retinal degeneration

    Article :112911

    Victoria Maneu, Pedro Lax, Antonio Miguel G. De Diego, Nicolás Cuenca, Antonio G. García

    Résumé Résumé Plan Plan  
  • ·Are mitophagy enhancers therapeutic targets for Alzheimer’s disease?

    Article :112918

    Jangampalli Adi Pradeepkiran, Ashly Hindle, Sudhir Kshirsagar, P. Hemachandra Reddy

    Résumé Résumé Plan Plan  
  • ·Immunomodulatory effect of mushrooms and their bioactive compounds in cancer: A comprehensive review

    Article :112901

    Manash Pratim Pathak, Kalyani Pathak, Riya Saikia, Urvashee Gogoi, Mohammad Zaki Ahmad, Pompy Patowary, Aparoop Das

    Résumé Résumé Plan Plan  
  • ·Cell plasticity in patients with NSCLC: The controversial origins of transformed SCLC

    Article :112909

    Xinlin Liang, Anqi Lin, Qiongyao Wang, Jian Zhang, Peng Luo

    Résumé Résumé Plan Plan  
  • ·Towards a precision immune checkpoint blockade immunotherapy in patients with colorectal cancer: Strategies and perspectives

    Article :112923

    Guanglin Cui

    Résumé Résumé Plan Plan  
  • ·Cell models for Alzheimer’s and Parkinson’s disease: At the interface of biology and drug discovery

    Article :112924

    Sandra Cetin, Damijan Knez, Stanislav Gobec, Janko Kos, Anja Pišlar

    Résumé Résumé Plan Plan  

• Original Articles

  • ·Efficacy of a multiple-indication antiviral herbal drug (Saliravira®) for COVID-19 outpatients: A pre-clinical and randomized clinical trial study

    Article :112729

    Reza Ramazani Khorshiddoust, Saleh Ramazani Khorshiddoust, Tahereh Hosseinabadi, Faezeh Mottaghitalab, Farzad Mokhtari, Fatemeh Azadinia, Hossein Mozdarani, Mohammad Shabani, Hamid Emadi-Kouchak, Bahram Taheri, Fatemeh Khani-Juyabad, Mina Amjadi Kashani, Arezoo Sadoughi, Sorour Zamanizadeh, Hadyeh Maddah, Maedeh Aminzadeh, Maryam Khanaki, Sabereh Saremi, Anahita Pashaee Rad, Ali Fatehi, Melika Ghaznavi Rad, Masoud Haftbaradaran, Mehran Khosroshahi, Mahtab Sadeghi, Majid Aminnayeri, Sirous Jafari, Fereshteh Ghiasvand, Arash Seifi, Sara Ghaderkhani, Seyed Ali Dehghan Manshadi, Mohammadreza Salehi, Ladan Abbasian, Malihe Hasannezhad, Mohsen Meidani, Mahboubeh Hajiabdolbaghi, Zahra Ahmadinejad, Masoud Parash, Zahra Sedighi, Abdorreza Mohammadian

    Résumé Résumé Plan Plan  
  • ·Preparation of a new component group of Ginkgo biloba leaves and investigation of the antihypertensive effects in spontaneously hypertensive rats

    Article :112805

    Hongbao Liang, Xiaomei Yuan, Chenghong Sun, Ying Sun, Min Yang, Shuai Feng, Jingchun Yao, Zhong Liu, Guimin Zhang, Feng Li

    Résumé Résumé Plan Plan  
  • ·Verapamil attenuates oxidative stress and inflammatory responses in cigarette smoke (CS)-induced murine models of acute lung injury and CSE-stimulated RAW 264.7 macrophages via inhibiting the NF-κB pathway

    Article :112783

    Ximei Wu, Musaddique Hussain, Shahzada Khurram Syed, Malik Saadullah, Ali M. Alqahtani, Taha Alqahtani, Afaf Aldahish, Mobeen Fatima, Saira Shaukat, Liaqat Hussain, Qurratulain Jamil, Imran Mukhtar, Kashif-ur-Rehman Khan, Ling-Hui Zeng

    Résumé Résumé Plan Plan   
  • ·Lactiplantibacillus plantarum inhibits colon cancer cell proliferation as function of its butyrogenic capability

    Article :112755

    Cristian Botta, Katerina Spyridopoulou, Marta Bertolino, Kalliopi Rantsiou, Katerina Chlichlia, Luca Cocolin

    Résumé Résumé Plan Plan   
  • ·Potential inhibitor for blocking binding between ACE2 and SARS-CoV-2 spike protein with mutations

    Article :112802

    Ming-Shao Tsai, Wei-Tai Shih, Yao-Hsu Yang, Yu-Shih Lin, Geng-He Chang, Cheng-Ming Hsu, Reming-Albert Yeh, Li-Hsin Shu, Yu-Ching Cheng, Hung-Te Liu, Yu-Huei Wu, Yu-Heng Wu, Rou-Chen Shen, Ching-Yuan Wu

    Résumé Résumé Plan Plan  
  • ·Analysis of the anti-inflammatory potential of Brassica bioactive compounds in a human macrophage-like cell model derived from HL-60 cells

    Article :112804

    Antonio José Ruiz-Alcaraz, María Antonia Martínez-Sánchez, Pilar García-Peñarrubia, María Martinez-Esparza, Bruno Ramos-Molina, Diego A. Moreno

    Résumé Résumé Plan Plan  
  • ·Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma

    Article :112796

    Huiyang Yuan, Yujiao Wu, Jing Wang, Xin Qin, Yongsheng Huang, Lei Yan, Yidong Fana, Jan Zedenius, C. Christofer Juhlin, Catharina Larsson, Weng-Onn Lui, Dawei Xu

    Résumé Résumé Plan Plan   
  • ·The in vitro anti-platelet activities of plant extracts from the Asteraceae family

    Article :112809

    Agata ROLNIK, Anna STOCHMAL, Beata OLAS

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  • ·Triclosan (TCS) affects the level of DNA methylation in the human oral squamous cell carcinoma (SCC-15) cell line in a nontoxic concentration

    Article :112815

    Konrad A. Szychowski, Bartosz Skóra, Monika Bar, Tomasz Piechowiak

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  • ·Targeting NLRP3 inflammasome modulates gut microbiota, attenuates corticospinal tract injury and ameliorates neurobehavioral deficits after intracerebral hemorrhage in mice

    Article :112797

    Linglong Xiao, Huaping Zheng, Jing Li, Meiqin Zeng, Dian He, Jianhao Liang, Kaijian Sun, Yunhao Luo, Feng Li, Baohong Ping, Wen Yuan, Hongwei Zhou, Qinghua Wang, Haitao Sun

    Résumé Résumé Plan Plan  
  • ·Minocycline treatment improves proteostasis during Drosophila aging via autophagy mediated by FOXO and Hsp70

    Article :112803

    Jin Ju Lim, Seogang Hyun

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  • ·Identification of bioactive natural products using yeast：Application to monoacylglycerol lipase inhibitor extraction from Corydalis Rhizoma

    Article :112798

    Jie Mei, Ruilin Guo, Fan Zhang, Haiyan Zhang, Xinping Yang, Boyang Yu, Jihua Liu, Xiufeng Liu

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  • ·Cyclolauranes as plausible chemical scaffold against Naegleria fowleri

    Article :112816

    Iñigo Arberas-Jiménez, Sara García-Davis, Aitor Rizo-Liendo, Ines Sifaoui, Ezequiel Q. Morales, José E. Piñero, Jacob Lorenzo-Morales, Ana R. Díaz-Marrero, José J. Fernández

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  • ·Supplementation of conventional anti-diabetic therapy with alpha-lipoic acid prevents early development and progression of diabetic nephropathy

    Article :112818

    George J. Dugbartey, Karl K. Alornyo, Benoit B. N'guessan, Stephen Atule, Samuel D. Mensah, Samuel Adjei

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  • ·Antifungal effects of alantolactone on Candida albicans: An in vitro study

    Article :112814

    Longfei Yang, Lili Zhong, Zhiming Ma, Yujie Sui, Jia’nan Xie, Xin Liu, Tonghui Ma

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  • ·Social isolation triggers oxidative status and impairs systemic and hepatic insulin sensitivity in normoglycemic rats

    Article :112820

    Maria Bove, Adriano Lama, Stefania Schiavone, Claudio Pirozzi, Paolo Tucci, Vladyslav Sikora, Giovanna Trinchese, Gaetano Corso, Maria Grazia Morgese, Luigia Trabace

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  • ·A novel brain-penetrant oral UGT8 inhibitor decreases in vivo galactosphingolipid biosynthesis in murine Krabbe disease

    Article :112808

    Eva Zaccariotto, María Begoña Cachón-González, Bing Wang, Sungtaek Lim, Bradford Hirth, Hyejung Park, Malika Fezoui, S.Pablo Sardi, Paul Mason, Robert H. Barker, Timothy M. Cox

    Résumé Résumé Plan Plan   
  • ·Targeting chalcone binding sites in living Leishmania using a reversible fluorogenic benzochalcone probe

    Article :112784

    Ariane S. Batista, Suellen D.S. Oliveira, Sébastien Pomel, Pierre-Henri Commere, Valérie Mazan, Moses Lee, Philippe M. Loiseau, Bartira Rossi-Bergmann, Eric Prina, Romain Duval

    Résumé Résumé Plan Plan   
  • ·Comparison of five diarrhea-predominant irritable bowel syndrome (IBS-D) rat models in the brain-gut-microbiota axis

    Article :112811

    Haomeng Wu, Kai Zhan, Kehan Rao, Huan Zheng, Shumin Qin, Xudong Tang, Shaogang Huang

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  • ·Gabapentinoid-induced peripheral edema and acute heart failure: A translational study combining pharmacovigilance data and in vitro animal experiments

    Article :112807

    Bérenger Largeau, Romain Bordy, Côme Pasqualin, Pierre Bredeloux, Jean-Luc Cracowski, Céline Lengellé, Valérie Gras-Champel, Marine Auffret, Véronique Maupoil, Annie-Pierre Jonville-Béra

    Résumé Résumé Plan Plan   
  • ·Intestinal epithelial cell-derived exosomes package microRNA-23a-3p alleviate gut damage after ischemia/reperfusion via targeting MAP4K4

    Article :112810

    Jin Yang, Xin Guo Zheng, Yan Ling Wu, Ai Ping Wang, Chen Hui Wang, Wen Xin Chen, Shan Zhong, Hui Yang

    Résumé Résumé Plan Plan  
  • ·Flavonolignans from silymarin modulate antibiotic resistance and virulence in Staphylococcus aureus

    Article :112806

    Kateřina Holasová, Bára Křížkovská, Lan Hoang, Simona Dobiasová, Jan Lipov, Tomáš Macek, Vladimír Křen, Kateřina Valentová, Tomáš Ruml, Jitka Viktorová

    Résumé Résumé Plan Plan   
  • ·Screening out key compounds of Glechomae Herba for antiurolithic activity and quality control based on spectrum-effect relationships coupled with UPLC-QDA

    Article :112829

    Jiaxu Zhang, Ajiao Hou, Jiaojiao Dong, Senwang Zheng, Huan Yu, Xuejiao Wang, Hai Jiang, Liu Yang

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  • ·Jiangzhi granule attenuates non-alcoholic steatohepatitis through modulating bile acid in mice fed high-fat vitamin D deficiency diet

    Article :112825

    Ying Cao, Xiangbing Shu, Meng Li, Siyu Yu, Chunlin Li, Guang Ji, Li Zhang

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  • ·Jiedu Huoxue decoction improves chronic abacterial prostatitis/chronic pelvic pain syndrome through activating Wnt/GSKβ/β-catenin signaling pathway and alleviating apoptosis

    Article :112830

    Jun Yi, Junqing Pan, Sina Zhang, Wenli Mao, Jiangang Wang, Wanchun Wang, Zhangren Yan

    Résumé Résumé Plan Plan  
  • ·Recombinant P40 protein of Schistosoma japonicum inhibits TREM-1 expression in RAW264.7 cells via FOXO3a

    Article :112826

    Pei Shen, Tianyu Zhang, Guo Chen, Bei Zhang, Ailong Huang, Lian Duan, Dandan Zhu, Jinling Chen, Jianxin Wang, Yinong Duan

    Résumé Résumé Plan Plan  
  • ·Hypoglycaemic activity of Oleanonic acid, a 3-oxotriterpenoid isolated from Aidia Genipiflora (DC.) Dandy, involves inhibition of carbohydrate metabolic enzymes and promotion of glucose uptake

    Article :112833

    Benjamin Kingsley Harley, Isaac Kingsley Amponsah, Inemesit Okon Ben, Nana Ama Mireku-Gyimah, Daniel Anokwah, David Neglo, Cedric Dzidzor K. Amengor, Theophilus Christian Fleischer

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  • ·Chemical profiles and pharmacological insights of Anisomeles indica Kuntze: An experimental chemico-biological interaction

    Article :112842

    Suaad Nasrin, Mohammad Nazmul Islam, Mohammed Abu Tayab, Mst. Samima Nasrin, Md. Abu Bakar Siddique, Talha Bin Emran, A.S.M. Ali Reza

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  • ·High frequency oscillations play important roles in development of epileptogenesis/ictogenesis via activation of astroglial signallings

    Article :112846

    Kouji Fukuyama, Motohiro Okada

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  • ·The influence of antioxidant dietary-derived polyphenolic combination on breast cancer: Molecular study

    Article :112835

    Afnan A. Alqarni, Aliaa A. Alamoudi, Rasha M. Allam, Ghada M. Ajabnoor, Steve M. Harakeh, Ahmed M. Al-Abd

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  • ·Cassia artemisiodes attenuates nociceptive and diabetes-induced neuropathic pain modalities apropos antioxidant and anti-inflammatory mechanisms

    Article :112834

    Rahim Ullah, Waseem Badshah, Gowhar Ali, Aman Ullah, Saleem Ullah Khan, Nisar Ahmad, Muhammad Shahid, Muhammad Naveed, Sami Ullah, Sudhair Abbas Bangash, Yusuf S. Althobaiti

    Résumé Résumé Plan Plan  
  • ·Protective effect of total Saponins from American ginseng against cigarette smoke-induced COPD in mice based on integrated metabolomics and network pharmacology

    Article :112823

    Hongqiang Lin, Caixia Wang, Hui Yu, Yunhe Liu, Luying Tan, Shanmei He, Zhuoqiao Li, Cuizhu Wang, Fang Wang, Pingya Li, Jinping Liu

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  • ·Butyrate emerges as a crucial effector of Zhi-Zi-Chi decoctions to ameliorate depression via multiple pathways of brain-gut axis

    Article :112861

    Jialin Liu, Yichao Fang, Lixun Cui, Zhongzhao Wang, Yusha Luo, Congcong Gao, Wen Ge, Taohong Huang, Jun Wen, Tingting Zhou

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  • ·Formononetin protects against inflammation associated with cerebral ischemia-reperfusion injury in rats by targeting the JAK2/STAT3 signaling pathway

    Article :112836

    Li Yu, Yangyang Zhang, Qianqian Chen, Yu He, Huifen Zhou, Haitong Wan, Jiehong Yang

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  • ·Metabolomics and integrated network analysis reveal roles of endocannabinoids and large neutral amino acid balance in the ayahuasca experience

    Article :112845

    Francisco Madrid-Gambin, Alex Gomez-Gomez, Arnau Busquets-Garcia, Noemí Haro, Santiago Marco, Natasha L. Mason, Johannes T. Reckweg, Pablo Mallaroni, Lilian Kloft, Kim van Oorsouw, Stefan W. Toennes, Rafael de la Torre, Johannes G. Ramaekers, Oscar J. Pozo

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  • ·Metformin modulates microbiota-derived inosine and ameliorates methamphetamine-induced anxiety and depression-like withdrawal symptoms in mice

    Article :112837

    Jiqing Yang, Zunyue Zhang, Zhenrong Xie, Ling Bai, Pu Xiong, Fengrong Chen, Tailin Zhu, Qingyan Peng, Hongjin Wu, Yong Zhou, Yuru Ma, Yongjin Zhang, Minghui Chen, Jianyuan Gao, Weiwei Tian, Kai Shi, Yan Du, Yong Duan, Huawei Wang, Yu Xu, Yi-Qun Kuang, Mei Zhu, Juehua Yu, Kunhua Wang

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  • ·Chemical characterization of extracts of leaves of Kadsua coccinea (Lem.) A.C. Sm. by UHPLC-Q-Exactive Orbitrap Mass spectrometry and assessment of their antioxidant and anti-inflammatory activities

    Article :112828

    Silin Shi, Kailin Li, Jie Peng, Jian Li, Lilan Luo, Mingjuan Liu, Yuqi Chen, Ziye Xiang, Pei Xiong, Lianghong Liu, Wei Cai

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  • ·Antidiabetic efficacy of Trifolium alexandrinum extracts hesperetin and quercetin in ameliorating carbohydrate metabolism and activating IR and AMPK signaling in the pancreatic tissues of diabetic rats

    Article :112838

    Heba M. Abdou, Fatma A. Hamaad, Esraa Y. Ali, Mamdooh H. Ghoneum

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  • ·Potential pathobionts in vaginal microbiota are affected by fish oil and/or probiotics intervention in overweight and obese pregnant women

    Article :112841

    Noora Houttu, Kati Mokkala, Wisam Tariq Saleem, Seppo Virtanen, Juuso Juhila, Ella Koivuniemi, Outi Pellonperä, Kristiina Tertti, Paula Luokola, Timo Sorsa, Anne Salonen, Leo Lahti, Kirsi Laitinen

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  • ·Synergistic antibacterial activity of tetrandrine combined with colistin against MCR-mediated colistin-resistant Salmonella

    Article :112873

    Kaifang Yi, Shuobo Liu, Peiyi Liu, Xingwei Luo, Jinfeng Zhao, Fengbin Yan, Yushan Pan, Jianhua Liu, Yajun Zhai, Gongzheng Hu

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  • ·Bioinformatics study of the potential therapeutic effects of ginsenoside Rf in reversing nonalcoholic fatty liver disease

    Article :112879

    Lichun Chen, Liziniu Wang, Weizhen Ao, Yu Chen, Songjian Li, Zhiguan Huang, Dan Yu, Yanwen Dong, Jiangyong Gu, Huiyan Zeng

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  • ·Glycyrrhiza uralensis Fisch. and its active components mitigate Semen Strychni-induced neurotoxicity through regulating high mobility group box 1 (HMGB1) translocation

    Article :112884

    Xiaoyu Duan, Jing Wen, Min Zhang, Chao Wang, Yalan Xiang, Lu Wang, Changwei Yu, Gongying Deng, Miao Yan, Bikui Zhang, Pingfei Fang

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  • ·Effect of Metaswitch® dietary supplement on anthropometric parameters, serum lipids, glucose level, oxidative stress and in vivo antioxidant properties in high fat diet-induced overweight Sprague Dawley rats

    Article :112892

    Benoit Banga N’guessan, Jessica Sarpongmaa Twumasi-Ankrah, Seth Kwabena Amponsah, Ismaila Adams, Albert Kyei-Kankam Poakwah, Charles Brown, Michael Buenor Adinortey, Joseph Adusei Sarkodie, Ofosua Adi-Dako, Isaac Julius Asiedu-Gyekye, Regina Appiah-Opong

    Résumé Résumé Plan Plan  
  • ·Cannabidiol improves glucose utilization and modulates glucose-induced dysmetabolic activities in isolated rats' peripheral adipose tissues

    Article :112863

    Ochuko L. Erukainure, Motlalepula G. Matsabisa, Veronica F. Salau, Kolawole A. Olofinsan, Sunday O. Oyedemi, Chika I. Chukwuma, Adeline Lum Nde, Md. Shahidul Islam

    Résumé Résumé Plan Plan  
  • ·Bioprophylactic potential of novel human colostrum probiotics via apoptotic induction of colon cancer cells and cell immune activation

    Article :112871

    Kantapich Srikham, Mongkol Thirabunyanon

    Résumé Résumé Plan Plan  
  • ·Lithium salts as a treatment for COVID-19: Pre-clinical outcomes

    Article :112872

    O. Soriano-Torres, E. Noa Romero, NL González Sosa, JM Enríquez Puertas, A. Fragas Quintero, M. García Montero, D. Martín Alfonso, Y. Infante Hernández, M. Lastre, L. Rodríguez-Pérez, Y. Borrego, VE González, IG Vega, R. Ramos Pupo, LM Reyes, MT Zumeta Dubé, Amaro Hernández, I. García de la Rosa, A. Minguez Suárez, LA Alarcón Camejo, M. Rodríguez, R. Oliva Hernández, CE Rudd, O. Pérez

    Résumé Résumé Plan Plan  
  • ·Niloticin inhibits osteoclastogenesis by blocking RANKL–RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways

    Article :112902

    Huanhuan Xu, Yuankan Jia, Jin Li, Xueqin Huang, Li Jiang, Ting Xiang, Yuanhao Xie, Xiaomei Yang, Titi Liu, Zemin Xiang, Jun Sheng

    Résumé Résumé Plan Plan   
  • ·Molecular networking-guided strategy for the pharmacokinetic study of herbal medicines: Cudrania tricuspidata leaf extracts

    Article :112895

    Jeong In Seo, Jun Sang Yu, Eun Kyu Lee, Ki Baek Park, Hye Hyun Yoo

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  • ·The enhanced mitochondrial dysfunction by cantleyoside confines inflammatory response and promotes apoptosis of human HFLS-RA cell line via AMPK/Sirt 1/NF-κB pathway activation

    Article :112847

    Jinrong Bai, Na Xie, Ya Hou, Xiaorui Chen, Yao Hu, Yi Zhang, Xianli Meng, Xiaobo Wang, Ce Tang

    Résumé Résumé Plan Plan  
  • ·A strategy for attenuation of acute radiation-induced lung injury using crocetin from gardenia fruit

    Article :112899

    Yan Ding, Lei Ma, Limin He, Quanxiao Xu, Zhuang Zhang, Zhen Zhang, Xinping Zhang, Rui Fan, Wenjun Ma, Ya’nan Sun, Baile Zhang, Wentai Li, Yao Zhai, Jiandong Zhang

    Résumé Résumé Plan Plan   
  • ·Inhibition of CDK7-dependent transcriptional addiction is a potential therapeutic target in synovial sarcoma

    Article :112888

    Xiaoyang Li, Dylan C. Dean, Jin Yuan, Thomas H. Temple, Jonathan C. Trent, Andrew E. Rosenberg, Shengji Yu, Francis J. Hornicek, Zhenfeng Duan

    Résumé Résumé Plan Plan   
  • ·The mechanism of the cytotoxic effect of Panax notoginseng extracts on prostate cancer cells

    Article :112887

    Benjamin Hawthorne, Kaleb Lund, Sydney Freggiaro, Risa Kaga, Jing Meng

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  • ·Spiraea prunifolia leaves extract inhibits adipogenesis and lipogenesis by promoting β-oxidation in high fat diet-induced obese mice

    Article :112889

    Ju-Hyoung Park, Eun-Kyung Ahn, Hye-Jin Ko, Min Hee Hwang, Young-Rak Cho, Dong-Ryung Lee, Bong-Keun Choi, Dong-Wan Seo, Joa Sub Oh

    Résumé Résumé Plan Plan   
  • ·Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota

    Article :112891

    Yanfang Zheng, Xian Zhou, Chenxiang Wang, Jialin Zhang, Dennis Chang, Shuting Zhuang, Wen Xu, Yong Chen, Xiaoning Wang, Lihong Nan, Yibin Sun, Xiaohui Lin, Wei Lin, Caigu He, Lian Dai, Jieping Zhang, Jianyu Chen, Hong Shi, Mingqing Huang

    Résumé Résumé Plan Plan   
  • ·Impact of anti-diabetic sodium-glucose cotransporter 2 inhibitors on tumor growth of intractable hematological malignancy in humans

    Article :112864

    Sawako Nakachi, Shiki Okamoto, Keita Tamaki, Ikumi Nomura, Mamiko Tomihama, Yukiko Nishi, Takuya Fukushima, Yuetsu Tanaka, Satoko Morishima, Minako Imamura, Shiro Maeda, Masato Tsutsui, Masayuki Matsushita, Hiroaki Masuzaki

    Résumé Résumé Plan Plan  
  • ·Tetralol derivative NNC-55-0396 induces glioblastoma cell death by activating IRE1α, JNK1 and calcium signaling

    Article :112881

    Anna Visa, Lía Alza, Carles Cantí, Judit Herreros

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  • ·Effect of amyloid-β on the redox system activity in SH-SY5Y cells preincubated with lipopolysaccharide or co-cultured with microglia cells

    Article :112880

    Benita Wiatrak, Paulina Jawień, Agnieszka Matuszewska, Adam Szeląg, Adriana Kubis-Kubiak

    Résumé Résumé Plan Plan  
  • ·Anxiolytic effects, metabolism and plasma pharmacokinetics of 3, 6′ -disinapoylsucrose

    Article :112913

    Jie Zhang, Jiaqi Xie, Yulu Liang, Yihong Li, Yongchun Zhang, Can Wang, Jianmei Huang

    Résumé Résumé Plan Plan   
  • ·Trigonelline prevents kidney stone formation processes by inhibiting calcium oxalate crystallization, growth and crystal-cell adhesion, and downregulating crystal receptors

    Article :112876

    Paleerath Peerapen, Wanida Boonmark, Visith Thongboonkerd

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  • ·Diacerein ameliorates letrozole-induced polycystic ovarian syndrome in rats

    Article :112870

    Yasmine F. Ibrahim, Mohammed Alorabi, Walaa Yehia Abdelzaher, Nisreen DM Toni, Khaled Thabet, AbdelRahman Hegazy, Haitham Ahmed Bahaa, Gaber El-Saber Batiha, Nermeen N. Welson, Mohamed A. Morsy, Katharigatta N. Venugopala, Asmaa Mohamed Abdel-Aziz

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  • ·Anti-adipogenic activity of maackiain and ononin is mediated via inhibition of PPARγ in human adipocytes

    Article :112908

    Saveta G. Mladenova, Martina S. Savova, Andrey S. Marchev, Claudio Ferrante, Giustino Orlando, Martin Wabitsch, Milen I. Georgiev

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  • ·Insulin like growth factor-1 works synergistically with dopamine to attenuate diabetic retinopathy by downregulating vascular endothelial growth factor

    Article :112868

    Shikha Upreti, Seema Sen, Tapas Chandra Nag, Madhumita P. Ghosh

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  • ·Disruption of hippocampal P2RX2/CaMKII/NF-κB signaling contributes to learning and memory impairment in C57BL/6 mice induced by surgery plus anesthesia in neonatal period

    Article :112897

    Weiming Zhao, Shaoyong Song, Wei Chu, Yixuan Li, Shiwen Chen, Yumeng Ji, Qingcai Chen, Xin Jin, Fuhai Ji

    Résumé Résumé Plan Plan   
  • ·Disclosing the antitumour potential of the marine bromoditerpene sphaerococcenol A on distinct cancer cellular models

    Article :112886

    Celso Alves, Joana Silva, Marta B. Afonso, Romina A. Guedes, Rita C. Guedes, Rebeca Alvariño, Susete Pinteus, Helena Gaspar, Márcia I. Goettert, Amparo Alfonso, Cecília M.P. Rodrigues, Maria C. Alpoím, Luis Botana, Rui Pedrosa

    Résumé Résumé Plan Plan  
  • ·Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell death in rats

    Article :112900

    Osama Y. Althunibat, Maisa Siddiq Abduh, Mohammad H. Abukhalil, Saleem H. Aladaileh, Hamza Hanieh, Ayman M. Mahmoud

    Résumé Résumé Plan Plan  
  • ·Development of a new polymer network system carrier of essential oils

    Article :112919

    Aurica P. Chiriac, Elena Stoleru, Irina Rosca, Alexandru Serban, Loredana Elena Nita, Alina Gabriela Rusu, Alina Ghilan, Ana-Maria Macsim, Liliana Mititelu-Tartau

    Résumé Résumé Plan Plan   
  • ·Diterpenoid alkaloids isolated from Delphinium trichophorum alleviate pulmonary fibrosis via the TGF-β/Smad pathway in 3T6 and HFL-1 cells

    Article :112906

    Yufeng Yao, Yuanyuan Chen, Dawa Zeren, Yunxia Ma, Yuanyuan Xie, Qian Wang, Huanhuan Ma, Meiqi Wang, Fangle Liu, Chenchen Zhu, Chaozhan Lin

    Résumé Résumé Plan Plan   
  • ·Analgesic and preventive effects of donepezil in animal models of chemotherapy-induced peripheral neuropathy: Involvement of spinal muscarinic acetylcholine M2 receptors

    Article :112915

    Marie Selvy, Catherine Mattévi, Cristelle Dalbos, Youssef Aissouni, Eric Chapuy, Pierre-Yves Martin, Aurore Collin, Damien Richard, Charles Dumontet, Jérôme Busserolles, Sakahlé Condé, David Balayssac

    Résumé Résumé Plan Plan   
  • ·BMP7-based peptide agonists of BMPR1A protect the left ventricle against pathological remodeling induced by pressure overload

    Article :112910

    Ana B. Salido-Medina, Aritz Gil, Víctor Expósito, Fernando Martínez, Juan M. Redondo, María A. Hurlé, J.Francisco Nistal, Raquel García

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  • ·Advanced cell therapy with low tissue factor loaded product NestaCell® does not confer thrombogenic risk for critically ill COVID-19 heparin-treated patients

    Article :112920

    Rodrigo Pinheiro Araldi, Benedito Carlos Prezoto, Vivian Gonzaga, Bruna Policiquio, Thais Biude Mendes, Fernanda D’Amélio, Hugo Vigerelli, Mariana Viana, Cristiane Wenceslau Valverde, Eduardo Pagani, Irina Kerkis

    Résumé Résumé Plan Plan   
  • ·Diacerein protects liver against APAP-induced injury via targeting JNK and inhibiting JNK-mediated oxidative stress and apoptosis

    Article :112917

    Mengyang Wang, Jinfeng Sun, Tianxiang Yu, Minxiu Wang, Leiming Jin, Shiqi Liang, Wu Luo, Yi Wang, Gao Li, Guang Liang

    Résumé Résumé Plan Plan   
  • ·Activation of α7nAChR preserves intestinal barrier integrity by enhancing the HO-1 / STAT3 signaling to inhibit NF-κB activation in mice

    Article :112733

    Wei Lei, Changcheng Zhao, Jiasen Sun, Yanling Jin, Zhijun Duan

    Résumé Résumé Plan Plan   
  • ·The multi-targeted tyrosine kinase inhibitor SKLB610 resensitizes ABCG2-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs

    Article :112922

    Chung-Pu Wu, Megumi Murakami, Yu-Shan Wu, Chun-Ling Lin, Yan-Qing Li, Yang-Hui Huang, Tai-Ho Hung, Suresh V. Ambudkar

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  • ·Effect of hydroxychloroquine and chloroquine on syncytial differentiation and autophagy in primary human trophoblasts

    Article :112916

    Minji Choi, Nagyeong Byun, Jae Ryoung Hwang, Yun-Sun Choi, Ji-Hee Sung, Suk-Joo Choi, Jung-Sun Kim, Soo-young Oh, Cheong-Rae Roh

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  • ·In vivo antitumor activity of Euphorbia lathyris ethanol extract in colon cancer models

    Article :112883

    C. Mesas, R. Martínez, K. Doello, R. Ortiz, M. López-Jurado, Francisco Bermúdez, F. Quiñonero, J. Prados, J.M. Porres, C. Melguizo

    Résumé Résumé Plan Plan  
  • ·Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits promoted by orexin-A/hypocretin-1

    Article :112925

    Marc Ten-Blanco, África Flores, Inmaculada Pereda-Pérez, Fabiana Piscitelli, Cristina Izquierdo-Luengo, Luigia Cristino, Julián Romero, Cecilia J. Hillard, Rafael Maldonado, Vincenzo Di Marzo, Fernando Berrendero

    Résumé Résumé Plan Plan   
  • ·Naringenin promoted spinal microglia M2 polarization in rat model of cancer-induced bone pain via regulating AMPK/PGC-1α signaling axis

    Article :112912

    Meng-Meng Ge, Dan-Yang Li, Lu Wang, Long-Qing Zhang, Dai-Qiang Liu, Yu-Ke Tian, Da-Wei Ye, Zhi-Heng Liu, Ya-Qun Zhou, Hui Yang

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  • ·Topical gel containing phenolic-rich extract from Ipomoea pes-capre leaf (Convolvulaceae) has anti-inflammatory, wound healing, and antiophidic properties

    Article :112921

    Jacinthia Beatriz Xavier-Santos, Júlia Gabriela Ramos Passos, Jacyra Antunes Santos Gomes, Joelly Vilaine Cavalcante Cruz, Jovelina Samara Ferreira Alves, Vinícius Barreto Garcia, Rodrigo Moreira da Silva, Norberto Peporine Lopes, Raimundo Fernandes Araujo-Junior, Silvana Maria Zucolotto, Arnóbio Antônio Silva-Junior, Juliana Félix-Silva, Matheus Freitas Fernandes-Pedrosa

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  • ·Losartan ameliorates renal interstitial fibrosis through metabolic pathway and Smurfs-TGF-β/Smad

    Article :112931

    Junju Zou, Xiaotao Zhou, Yuerong Ma, Rong Yu

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• Short Communications

  • ·Pharmacokinetics of chloroquine in patients with malaria by P. vivax from the Western Brazilian Amazon basin

    Article :112874

    Marly M. Melo, Monica R.F. Costa, Franklin S.Santana Filho, José Diego Brito-Sousa, Anne C.G. Almeida, Wuelton M. Monteiro, Gisely C. Melo, José Luiz Fernandes Vieira, Maria das Graças Costa Alecrim

    Résumé Résumé Plan Plan

• Letters to the Editor

  • ·Synergistic effect of antimetabolic and chemotherapy drugs in triple-negative breast cancer

    Article :112844

    Elena López-Camacho, Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Irene Dapía, Rocío López-Vacas, Andrea Zapater-Moros, María Isabel Lumbreras-Herrera, Pedro Arias, Pilar Zamora, Juan Ángel Fresno Vara, Enrique Espinosa

    Résumé Résumé Plan Plan   

• Corrigendum

  • ·Corrigendum to “Schisandrin A inhibits triple negative breast cancer cells by regulating Wnt/ER stress signaling pathway” [Biomed. Pharmacother. 115 (2019) 108922]

    Article :112865

    Xiaohong Xu, Vinothakumar Rajamanicham, Sujing Xu, Zhoudi Liu, Tao Yan, Guang Liang, Guilong Guo, Huiping Zhou, Yi Wang

    
  • ·Corrigendum to “XIAOPI formula promotes breast cancer chemosensitivity via inhibiting CXCL1/HMGB1-mediated autophagy” [Biomed. Pharmacother. 120 (2019) 109519]

    Article :112867

    Neng Wang, Bowen Yang, Gulizeba Muhetaer, Shengqi Wang, Yifeng Zheng, Jiahong Lu, Min Li, Fengxue Zhang, Honglin Situ, Yi Lin, Zhiyu Wang

     

• Retractions

  • ·Retraction notice to “MicroRNA-19a promotes cell viability and migration of chondrocytes via up-regulating SOX9 through NF-κB pathway” [Biomed. Pharmacother. 98 (2018) 746–753]

    Article :112790

    Chuandong Yu, Yongkun Wang

    
  • ·Retraction notice to "Schizandrin A enhances chemosensitivity of colon carcinoma cells to 5-fluorouracil through up-regulation of miR-195" [Biomed Pharmacother 99 (2018) 176–183]

    Article :112791

    Dongfang Kong, Deyong Zhang, Xianqun Chu, Jing Wang

    
  • ·Retraction notice to “Piperine alleviates lipopolysaccharide-induced inflammatory injury by down-regulating microRNA-127 in murine chondrogenic ATDC5 cells” [Biomed. Pharmacother. 103 (2018) 947–954]

    Article :112792

    Chunfeng Ren, Zhiyuan Liang

    
  • ·Retraction notice to “Long non-coding RNA TUG1 protects renal tubular epithelial cells against injury induced by lipopolysaccharide via regulating microRNA-223” [Biomed. Pharmacother. 104 (2018) 509–519]

    Article :112793

    Yan Xu, Wenyan Deng, Wei Zhang

    
  • ·Retraction notice to “Tanshinone IIA ameliorates lipopolysaccharide-induced inflammatory response in bronchial epithelium cell line BEAS-2B by down-regulating miR-27a” [Biomed. Pharmacother. 104 (2018) 158–164]

    Article :112794

    Xiuxia Liu, Jie Meng

    
  • ·Retraction notice to "Knockdown of lncRNA XIST inhibits retinoblastoma progression by modulating the miR-124/STAT3 axis" [Biomed. Pharmacother. 107(2018) 547–554]

    Article :112795

    Chunmei Hu, Shu Liu, Mei Han, Yingxue Wang, Chunling Xu

    
  • ·Retraction notice to “Sinomenine inhibits lipopolysaccharide-induced inflammatory injury by regulation of miR-101/MKP-1/JNK pathway in keratinocyte cells” [Biomed. Pharmacother. 101 (2018) 422–429]

    Article :112848

    Shumei Liu, Yigang Man, Li Zhao

    
  • ·Retraction notice to “Astragalus polysaccharide protects hypoxia-induced injury by up-regulation of miR-138 in rat neural stem cells” [Biomed. Pharmacother. 102 (2018) 295–301]

    Article :112849

    Zebao Zheng, Bing Zhao