Sommaire

• • ·Surgical Forum Opener

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• • ·Surgical Forum 2006

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    Plan Plan

• Introduction

  • ·Introduction

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    Résumé Résumé Plan Plan

• Dedication

  • ·The 57^th Volume of the Surgical Forum is dedicated to Jonathan L Meakins, MD, FACS

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    Ori D. Rotstein

     

• Surgical Forum Dedications

  • ·Surgical Forum Dedications

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• Excellence in Research Awards

  • ·American College of Surgeons Forum on Fundamental Surgical Problems Resident/Fellow Excellence in Research Awards 2006

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    American College of Surgeons

    Plan Plan  

• Alimentary Tract I

  • ·Postoperative effects of laparotomy on LPS induced gastric injury

    Page :S13

    Benjamin A. Delano, Sasha Adams, David Mercer

    Plan Plan
  • ·A comparison of the rate of resolution of diabetes mellitus after laparoscopic adjustable-gastric banding, gastric bypass and biliopancreatic diversion with duodenal switch

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    Manish S. Parikh, Patricia Ayoung-Chee, Eleny Romanos, Nichole Lewis, Christine Ren

    Plan Plan
  • ·Tapping the zinc sink: Mitochondrial regulation of intracellular Zn2+ loading

    Page :S11

    Haley B. Naik, Laura Owings, David I. Soybel

    Plan Plan
  • ·Transforming growth factor-beta (TGF-beta) signaling may play a protective role in preventing liver from insulin induced steatosis by regulating insulin driven AKT inactivation of forkhead transcriptional factor proteins

    Page :S10

    Krit Kitisin, Natarajan Ganesan, Yi Tang, Varalakshmi Katuri, Nady Golestaneh, Wilma Jogunoori, Kirti Shetty, Lopa Mishra, Lynt Johnson

    Plan Plan
  • ·Augmentation of hepatic stem cell provides the liver with tolerance against ischemia-reperfusion injury

    Page :S11

    Tsutomu Sato, Yuki Abe, Go Watanabe, Hiroshi Nanjo, Makoto Kume, Hiroshi Uchinami, Satoshi Shibata, Yuzo Yamamoto

    Plan Plan
  • ·PI3K/AKT activation is critical for hepatic regeneration after partial hepatectomy

    Page :S11

    Lindsey N. Jackson, Shawn D. Larson, Scott R. Silva, Junji Ueda, L. Andy Chen, B. Mark Evers

    Plan Plan
  • ·Regulation of liver regeneration by suppressors of cytokine signaling-3

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    Kimberly J. Riehle, Ben Croker, Jean Campbell, Nelson Fausto

    Plan Plan
  • ·Insulin administration to insulin-resistant mice worsens in vivo gallbladder emptying

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    Hayder H. Al-Azzawi, Abhishek Mathur, Debao Lu, Deborah Swartz-Basile, Attila Nakeeb, Henry A. Pitt

    Plan Plan
  • ·Inhibition of phosphatidylinositol 3-kinase inhibits intracellular zymogen activation but not enzyme secretion in pancreatic acinar cells

    Page :S13

    L. Andy Chen, Hiroki Watanabe, B. Mark Evers

    Plan Plan
  • ·Mitochondrial reactive oxygen species mediate dicumarol-induced cytotoxicity in pancreatic cancer cells

    Page :S13

    David H. Daniels, Juan Du, Carla Asbury, Larry W. Oberley, Joseph J. Cullen

    Plan Plan
  • ·Somatic genetic engineering of the murine endocrine pancreas results in novel model of nonimmune, pancreatogenic diabetes

    Page :S13

    Shihe Liu, Xiao-ping Wang, Zhijun Li, Nikiforos Ballian, Davis Alan, F. Charles Brunicardi

    Plan Plan
  • ·Tumor endothelial cell targeting by a Shiga-like Toxin-VEGF fusion protein: a novel therapy for pancreatic cancer

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    Hubert G. Hotz, Joseph M. Backer, Marina V. Backer, Birgit Hotz, Heinz J. Buhr

    Plan Plan

• Alimentary Tract II

  • ·Activation of ERK is critical for glutamine-mediated intestinal cell survival

    Page :S18

    Shawn D. Larson, Dai H. Chung, B. Mark Evers

    Plan Plan
  • ·Total extrinsic jejunoileal denervation: Effects on hexose transporter expression

    Page :S15

    Scott G. Houghton, Javairiah Fatima, Judith A. Duenes, Michael G. Sarr

    Plan Plan
  • ·Postoperative ileus: Mechanical activation of intestinal macrophages and smooth muscle cells

    Page :S15

    Sven Wehner, Silke Schuchtrup, Anatol Rocke, Andreas Hirner, Joerg Kalff

    Plan Plan
  • ·Intestinal dendritic cells (DC) and CCR7 are centrally involved in the gastrointestinal field effect

    Page :S16

    Arne J. Koscielny, Daniel Engel, Sven Wehner, Christian Kurts, Jörg Kalff

    Plan Plan
  • ·A neurokinin 1 receptor antagonist (NK-1RA) decreases adhesion reformation after laparoscopic lysis of adhesions (LOA) in a rat model

    Page :S16

    Scott G. Prushik, Cary B. Aarons, Ronald Matteotti, Karen L. Reed, Adam C. Gower, Arthur F. Stucchi, James M. Becker

    Plan Plan
  • ·Microvascular adaptations associated with lymphocyte slowing and transmigration in acute colitis

    Page :S16

    Dino J. Ravnic, Moritz Konerding, Harold Huss, Juan Pratt, Steven Mentzer

    Plan Plan
  • ·Controlled fabrication of engineered small intestinal grafts using polycaprolactone and polyurethane scaffolds

    Page :S17

    Shaun M. Kunisaki, Cathryn Sundback, Nicholas Krebs, Erin Ochoa, Joseph Vacanti

    Plan Plan
  • ·Lipopolysaccharide-induced intestinal glutamine absorption increase is mediated by hartnup disorder associated B0AT1 gene

    Page :S17

    Brynn S. Wolff, Qing He Meng, Wiley Souba, Anne Karinch, ChengMao Lin, Laura Tunke, Ming Pan

    Plan Plan
  • ·Ulcerative colitis inpatients are at increased risk for thromboembolic events

    Page :S17

    Jennifer Y. Wang, Jonathan Terdiman, Madhulika Varma

    Plan Plan
  • ·Old age and laparotomy adversely affect abdominal muscle mechanical properties

    Page :S18

    Melanie Urbanchek, Shaun Patel, Albert Ma, Thane Wolcott, Erika Henkelman, Michael Franz, William Kuzon

    Plan Plan
  • ·Pretreatment with BMP-7 mimics protective effects of ischemic preconditioning (IPC) following intestinal ischemia/reperfusion (IR) injury in the intestine and liver

    Page :S18

    Ravi S. Radhakrishnan, Geetha Ramaswamy, Hari Radhakrishnan, Sasha Adams, Bradley Saunders, Kumar Felix, Stacey Moore-Olufemi, Frederick Moore, Charles Cox, Bruce Kone

    Plan Plan
  • ·A novel autocrine serotonin receptor in enterochromaffin cells

    Page :S19

    Jarrod D. Day, Roberto C. Iglesias, Dorne R. Yager, John M. Kellum

    Plan Plan

• Cardiothoracic Surgery

  • ·Regression of pressure-induced left ventricular hypertrophy is associated with distinct patterns of developmental gene expression

    Page :S23

    William E. Stansfield, Mauricio Rojas, Ruhang Tang, Craig H. Selzman

    Plan Plan
  • ·The debate between transhiatal and transthoracic esophagectomy: A five-year prospective cohort of 17,395 patients

    Page :S20

    Rafe Connors, Brian Reuben, Leigh Neumayer, David Bull

    Plan Plan
  • ·Comparison of video assisted thoracoscopic surgery to thoracotomy for resection of clinical stage I non-small cell lung cancer

    Page :S20

    Bryan Whitson, Adam Boettcher, Ricardo Bardales, Robert Kratzke, Peter Dahlberg, Rafael Andrade, Michael Maddaus

    Plan Plan
  • ·Deficiency of TNFR1 protects myocardium through STAT3, SOCS3, and IL-6, but not p38 MAPK or IL-1 beta

    Page :S21

    Meijing Wang, Paul Crisostomo, Keith Lillemoe, Daniel Meldrum

    Plan Plan
  • ·Regional systolic and remodeling strain differences during cardiac remodeling

    Page :S21

    Ahmet Kilic, G. Kwame Yankey, Tim Nolan, Tieluo Li, Jennifer Nash, Guangming Cheng, Zhongjun Wu, Bartley Griffith

    Plan Plan
  • ·Finite element analysis of transmural stress in left ventricular aneurysm

    Page :S21

    Amod P. Tendulkar, Joseph Walker, Julius Guccione, Mark Ratcliffe

    Plan Plan
  • ·Murine carotid aneurysms develop without down regulation of Nogo-B expression: A novel model for human thoracic aneurysms

    Page :S22

    Stephen P. Maloney, Alexander Yakimov, Akihito Muto, Paul Tang, Jose Pimiento, Fabio Kudo, Tormod Westvik, Stanley Dudrick, William Sessa, George Tellides, Alan Dardik

    Plan Plan
  • ·Survival of human marrow stem cells (MSCs) implanted into acutely infarcted rat myocardium: A xenotransplant model

    Page :S22

    Rony Atoui, Juan Francisco Asenjo, Minh Duong, Ray Chiu, Dominique Shum-Tim

    Plan Plan
  • ·Cardiopulmonary bypass with cardioplegic arrest activates protein kinase C in the human myocardium

    Page :S22

    Neel R. Sodha, Richard Clements, Jun Feng, Munir Boodhwani, Basel Ramlawi, Shigetoshi Mieno, Cesario Bianchi, Frank W. Sellke

    Plan Plan
  • ·Diazoxide prevents myocyte swelling and reduced contractility secondary to ischemic stress: A potential role in myocyte volume regulation?

    Page :S23

    Ashraf S. Al-Dadah, Andreas Zierer, Rochus K. Voeller, Richard B. Schuessler, Ralph J. Damiano, Jennifer S. Lawton

    Plan Plan
  • ·The utility of coronary artery bypass graft (CABG) surgery report cards beyond mortality rates

    Page :S23

    Veena Guru, Stephen Fremes, Geoffrey Anderson, C. David Naylor, Christopher Feindel, Fraser Rubens, Richard Novick, Jack Tu

    Plan Plan
  • ·Retrograde cardioplegia: Real time visualization and quantification

    Page :S24

    Aravind Rangaraj, Ravi Ghanta, Ramanan Umakanthan, Edward Soltesz, Rita Laurence, John Fox, Lawrence Cohn, Ralph Bolman, John Frangioni, Frederick Chen

    Plan Plan

• Critical Care I

  • ·Probiotics potentiate IL-6 production in IL-1 beta-treated enterocytes through a heat shock-dependent mechanism

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    Natasha Reilly, Vitaliy Poylin, Michael Menconi, Andrew Onderdonk, Stig Bengmark, Per-Olof Hasselgren

    Plan Plan
  • ·After major injury regulatory T-cells reduce inflammation and mortality from a ’second hit’

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    Ann M. McKenna, Malcolm P. MacConmara, Satoshi Fujimi, James A. Lederer, John A. Mannick

    Plan Plan
  • ·Hypoxia induced pre-reperfusion response is critical for ischemic acute tubular necrosis

    Page :S25

    Xingju Nie, Zhen Wang, Edwin Rodriguez, Ashley Chi, Michael Longaker, George Yang

    Plan Plan
  • ·Oxidant-induced Akt phosphorylation in murine macrophages involves ceramide generation through the acid sphingomyelinase pathway

    Page :S26

    Patrick S. Tawadros, Simone E. Birch, Min Zou, Katalin Szaszi, Andras Kapus, Ori D. Rotstein

    Plan Plan
  • ·Electro-gene transfer of the b1 Na+, K+-ATPase pump in lipopolysaccharide (LPS) injured murine lungs

    Page :S26

    David Machado-Aranda, Vijay Mittal

    Plan Plan
  • ·Heme oxygenase–1(HO-1)/carbon monoxide(CO) inhibit apoptotic signaling via a NFKB dependent pathway

    Page :S27

    Raghuveer Vallabhaneni, Hoe Suk Kim, Timothy Billiar, Brian Zuckerbraun

    Plan Plan
  • ·High-mobility group box 1 (HMGB1) release in response to hypoxia is calcium dependent

    Page :S27

    Geetha Jeyabalan, Allan Tsung, John Klune, Timothy Billiar, David Geller

    Plan Plan
  • ·Fer kinase is a novel regulator of Jak/STAT signaling pathway

    Page :S27

    Simone E. Birch, Patrick Tawadros, Katalin Szaszi, Andras Kapus, Ori D. Rotstein

    Plan Plan
  • ·The NF-kB inhibitor curcumin reduces protein breakdown in septic muscle

    Page :S28

    Vitaliy Y. Poylin, Per-Olof Hasselgren, Moun Fareed

    Plan Plan
  • ·Hepatoprotection and lethality rescue by the histone deacetylase inhibitor valproic acid

    Page :S28

    Earl Gonzales, Huazhen Chen, Richard Munuve, David Burris, Elena Koustova

    Plan Plan
  • ·Catecholamines and IL-4 synergize to induce arginase in myeloid suppressor cells after trauma

    Page :S28

    Petar J. Popovic, Benjamin Matta, Christopher Follansbee, Juan Ochoa

    Plan Plan
  • ·Lymphocyte phenotype distinguishes septic from nonseptic critical illness

    Page :S26

    Steven J. Schwulst, Jared Muenzer, Katherine Chang, Richard Hotchkiss

    Plan Plan

• Critical Care II

  • ·Beneficial effects of CpG DNA treatment on injury-induced changes in host immunity

    Page :S33

    Satoshi Fujimi, Malcolm P. Mac Conmara, Ann M. McKenna, Adam Delisle, Peter H. Lapchak, John A. Mannick, James A. Lederer

    Plan Plan
  • ·Splenectomy improves survival in experimental polymicrobial sepsis

    Page :S30

    Jared M. Huston, Mahendar Ochani, Kanta Ochani, Margot Gallowitsch Puerta, Mala Ashok, Mauricio Rosas-Ballina, Huan Yang, Christopher Czura, Luis Ulloa, Kevin Tracey

    Plan Plan
  • ·Aging and fitness: Determining factors of inconspicuous hypoxia?

    Page :S30

    Hector J. Menchaca, Thomas Rohde, Christie Heikes, Elizabeth Arendt, Henry Buchwald

    Plan Plan
  • ·Nitrite, a hypoxia selective nitric oxide donor, limits renal ischemia-reperfusion injury in non-human primates

    Page :S31

    Kiran K. Dhanireddy, David A. Bruno, Sruti Shiva, Frank V. Leopardi, Xiaojie Zhang, Mark Gladwin, Allan D. Kirk

    Plan Plan
  • ·Inhibition of NF-KB does not induce JNK mediated apoptosis in reperfusion injury

    Page :S31

    Gregory D. Rushing, Michael Doviak, L.D. Britt

    Plan Plan
  • ·Induction of profound hypothermia improves survival in a swine model of complex vascular, splenic and colonic injuries, without an increase in bleeding and septic complications

    Page :S31

    Elizabeth Sailhamer, Zheng Chen, Peter Rhee, George Velmahos, Marc De Moya, Hasan Alam

    Plan Plan
  • ·Resuscitation with normal saline (NS) increased volume requirement, increased cardiac output and decreased systemic vascular resistance compared to lactated ringers (LR) in an uncontrolled hemorrhagic shock model in swine

    Page :S32

    Brandon Tieu, T. Miko Enomoto, Charles Phillips, Daniel Hagg, Tracy Wiesberg, Patrick Muller, Martin Schreiber

    Plan Plan
  • ·Fluid restriction in novel clinically-relevant model of polytrauma

    Page :S32

    Steven A. Earle, Marc A. DeMoya, Jennifer E. Zuccarelli, Kenneth G. Proctor

    Plan Plan
  • ·Comparison of prolonged hypotensive and normotensive resuscitation strategies in a porcine model of hemorrhagic shock

    Page :S32

    David E. Skarda, Gregory Beilman, Kristine Mulier, Michelle Dunning

    Plan Plan
  • ·15-deoxy-Delta12,14-PGJ2 (15d-PGJ2), a ligand of the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARgamma), mediates repression of TNFalpha by decreasing levels of acetylated H4

    Page :S33

    Ryan Engdahl, Alex Monroy, John Daly

    Plan Plan
  • ·OxyR gene expression of Pseudomonas aeruginosa regulates bone marrow dendritic cell differentiation and function after burn sepsis

    Page :S34

    Kurt A. Melstrom, Kuzhali Muthu, Li-Ke He, Jason Smith, Andrea Szilagyi, Daniel Hassett, Richard Gamelli, Ravi Shankar

    Plan Plan
  • ·Natural killer dendritic cells proliferate and secrete IFN-gamma during sepsis

    Page :S33

    George Plitas, Umer Chaudhry, Peter Kingham, Jennifer Stableford, Jesse Raab, Ronald DeMatteo

    Plan Plan

• Gynecology/Neurosurgery/Orthopaedic Surgery

  • ·Transductional and transcriptional targeting enhances adenoviral virotherapy of malignant glioma

    Page :S38

    Maciej Lesniak, Ilya Ulasov, Zeng Zhu, David Curiel

    Plan Plan
  • ·Derivation of human motoneurons from embryonic stem cells for transplantation

    Page :S35

    George I. Al Shamy, Hyojin Lee, Yechiel Elkabetz, Lorenz Studer, Viviane Tabar

    Plan Plan
  • ·The effect of hyperbaric oxygen on primary osteoblasts in vitro

    Page :S35

    Marc A. Soares, Alex Wong, Sen Li, Peter Cordeiro, Babak Mehrara

    Plan Plan
  • ·Normal neuromuscular development of the lower gastrointestinal tract and anorectum in fetal rats with retinoic acid induced myelomeningocele - implications for fetal surgery

    Page :S36

    Enrico Danzer, Antoneta Radu, MaryAnn Volpe, N. Scott Adzick, Alan Flake

    Plan Plan
  • ·How we die: The impact of non-neurological organ dysfunction following traumatic brain injury

    Page :S36

    Clinton D. Kemp, Bryan Cotton, Chad Johnson, Kyle Weaver

    Plan Plan
  • ·Primary mega-prosthetic replacement versus salvage mega-prosthesis in the treatment of proximal femoral trauma

    Page :S36

    Andrew Schoenfeld, Mark Leeson, Gregory Vrabec

    Plan Plan
  • ·Retinoic acid induces differential expression of MMP-1&-9 in fetal and adult fibroblasts

    Page :S37

    Anuja K. Antony, Sina Bari, Michael Longaker, H. Peter Lorenz

    Plan Plan
  • ·Low grade gliomas of the elderly: Characterizing a rare entity

    Page :S37

    Nader Pouratian, Melike Mut, M. Beatriz Lopes, David Schiff, Mark Shaffrey

    Plan Plan
  • ·Serum-mediated osteogenic effect of traumatic brain injured patients

    Page :S37

    Oliver P. Gautschi, Karen Joesbury, James Meagher, Allan Skirving, Luis Filgueira, René Zellweger

    Plan Plan
  • ·Role of beta-catenin in regulating vascular endothelial growth factor A (VEGF-A) expression in endometrial cancer

    Page :S38

    Bhavana Pothuri, Marina Vorontchikhina, Thomas Herzog, Carmel Cohen, Thomas Wright, Jan Kitajewski

    Plan Plan
  • ·Treatment of displaced multiple fragment fractures of the proximal humerus with the Delta CTA reverse shoulder prosthesis in the elderly patient

    Page :S38

    Michael Klein, Miriam Juschka, Bernd Hinkenjann, Bernhard Scherger, Peter A.W. Ostermann

    Plan Plan

• Multi-Disciplinary Session I

  • ·TLR4-competent hematopoietic cells are required for systemic inflammation and hepatic injury after trauma/hemorrhage

    Page :S42

    Kevin P. Mollen, Jose Prince, Ryan Levy, Melanie Scott, Gregory Watson, David Kaczorowski, Lauryn K. Kohut, Hoffman Rosemary, Yoram Vodovotz, Timothy Billiar

    Plan Plan
  • ·Could human umbilical cord blood be used to regenerate damaged myocardium?

    Page :S39

    Tamer Malik, Richard Fogler, Wu Gui Fu

    Plan Plan
  • ·Highly enriched mesenchymal stem cells (MSC) can initiate sarcoma formation in vivo

    Page :S39

    Monika Tataria, Unsal Kuscuoglu, Ailles Lauire, Samuel Cheshier, Roel Nusse, Irving Weissman, Sylvester Karl

    Plan Plan
  • ·The role of endothelial and hepatic progenitor cell interactions in organogenesis

    Page :S40

    Maggie H. Walkup, Lisa L. Rice, Natasha R. Wright, Prakash Chandrasekaran, David A. Gerber

    Plan Plan
  • ·SDF-1A and hyperoxia synergistically increase circulating endothelial progenitor cells and wound healing in diabetic mice

    Page :S40

    Katherine A. Gallagher, Lee Goldstein, April Nedeau, Haiying Chen, Don Buerk, Jun Lui, Stephen Thom, Omaida Velazquez

    Plan Plan  
  • ·Implantation of peritoneal mononuclear cells induce neovascularization in a rat ischemic hindlimb model: A novel and conventional cell source for angiogenesis therapy

    Page :S41

    Nobuyuki Hirose, Hironori Maeda, Morio Yamamoto, Rao Parijatha, Geethalakshmi Radhakrishnan, Yutong Xing, Shiro Sasaguri

    Plan Plan
  • ·Transplantation of GABAergic human neural precursor cells into multiple basal ganglia targets enhances complex sensorimotor behavioral recovery in parkinsonian rodents

    Page :S41

    Karim Mukhida, Murray Hong, Ivar Mendez

    Plan Plan
  • ·Rhesus EB cultures exhibit functional hemangioblast activity during hematopoietic differentiation

    Page :S41

    Aimen F. Shaaban, Lasya Gaur, Deepika Rajesh

    Plan Plan
  • ·Fluorescence-activated cell sorting with CD105 identifies osteoprogenitors within mouse and human-derived AMCs

    Page :S42

    Derrick C. Wan, Matthew Kwan, Randall Nacamuli, Monika Tataria, Michael Longaker

    Plan Plan
  • ·In vivo systemic delivery of bone marrow-derived mesenchymal stromal cells results in enhanced fascial wound healing

    Page :S42

    David S. Kwon, Tina Gao, Bo Liu, Deborah Dulchavsky, Scott Dulchavsky, Subhash Gautam

    Plan Plan
  • ·Allogeneic bone marrow cells co-infused with stromal stem cells for induction of vascularized skin allograft survival

    Page :S42

    Elaine K. Horibe, Emre Aksu, Justin Sacks, Ryosuke Ikeguchi, Yur-Ren Kuo, Jignesh Unadkat, Jeremy Breitinger, Andrew Lee, Maryam Feili-Hariri

    Plan Plan
  • ·Accelerated diabetic wound healing in a murine model with the application of multipotent human adipose derived stem cells

    Page :S43

    Anna M. Parker, George Rodeheaver, Lisa Salopek, Hulan Shang, Moshe Khurgel, Adam Katz

    Plan Plan
  • ·The in vivo application of amniotic fluid stem cells for the repair of kidney damage after glycerol induced tubulonecrosis

    Page :S43

    Stefano Giuliani, Laura Perin, Sargis Sedrakyan, David Warburton, Roger De Filippo

    Plan Plan

• Multi-Disciplinary Session II

  • ·Molecular profiling of inflammatory genes predicts tumor positivity of sentinel nodes in melanoma

    Page :S47

    Hitoe Torisu-Itakura, Randall Scheri, Young Huynh, Xing Ye, Richard Essner

    Plan Plan
  • ·Deletion of TGF-beta receptor Alk5 in the epithelium results in cleft palate

    Page :S44

    Wai-Yee Li, Marek Dudas, Jieun Kim, Andre Nagy, Vesa Kaartinen

    Plan Plan
  • ·Cortisol alters tnf-receptor associated factor expression in vivo before and after IPS exposure

    Page :S44

    Sonia M. Alvarez, Susette Coyle, Marie Macor, Jacqueline Calvano, Michael Reddell, Ashwini Kumar, Steven Calvano, Stephen Lowry

    Plan Plan
  • ·Transcriptional profiling of ischemic preconditioning in rat intestine following ischemia/reperfusion injury

    Page :S45

    Stacey D. Moore-Olufemi, Steve Lott, Shodimu-Emmanuel Olufemi, Norio Sato, Rosemary Kozar, Fred Moore, Ravi Radhakrishnan, Charles Cox, Bruce Kone

    Plan Plan
  • ·HMGA1: A mediator of metastasis and a novel prognostic marker in pancreatic adenocarcinoma

    Page :S45

    Siong-Seng Liau, Flavio Rocha, Evan Matros, Edward Whang

    Plan Plan
  • ·Secretory phospholipase A2 and other IL-6 pathway related genes are upregulated in the media and adventitia of aneurysmal aorta: A microdissection analysis

    Page :S45

    John Curci, Ashoka Polpitiya, J. Perren Cobb, Timothy Tolley, Batool Arif, Beth Frazier, Robert Thompson

    Plan Plan
  • ·Inactivation and restoration of transforming growth factor-beta (TGF-beta) signaling modulated carcinogenesis in hepatocellular cancer(HCC) cell lines and elf+/− tissues

    Page :S46

    Krit Kitisin, Natarajan Ganesan, Eugene Volpe, Sang Kim, Varalakshmi Katuri, Yi Tang, Bibhutibhushan Mishra, Lopa Mishra, Kirti Shetty, Lynt Johnson

    Plan Plan
  • ·Sonic hedgehog pathway—a potential target for pancreatic adenocarcinoma treatment

    Page :S46

    Elena Y. Rakhlin, David Rosow, Aram Hezel, Oliver Strobel, Mari Mino-Kenudson, Amy Stirman, Elaina Mikhailova, Carlos Fernandez del Castillo, Andrew Warshaw, Sarah Thayer

    Plan Plan
  • ·Overexpression of insulin-like growth factor 2 in colorectal cancer

    Page :S47

    Kamran Idrees, Li-Xuan Qin, Yu-Wei Cheng, Zhaoshi Zeng, Selvanze Zachariah, Dan Notterman, Francis Barany, Philip Paty

    Plan Plan
  • ·Over expression of human microRNAs contribute to follicular thyroid carcinogenesis (FTC)

    Page :S47

    Frank Weber, Michael Radmacher, Christoph E. Broelsch, Andrea Frilling, Charis Eng

    Plan Plan
  • ·Early differential genetic expression during acute mesenteric ischemia, potetiation with reperfusion, and relative contributions of inflammatory and reparative modulators

    Page :S47

    William B. Keeling, Steven A. Enkemann, Patrick A. Stone, Sean J. Yoder, Robert S. Brumberg, Brad L. Johnson, Dennis F. Bandyk, Murray L. Shames, Martin R. Back

    Plan Plan
  • ·Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury

    Page :S48

    William E. Stansfield, Ashwani K. Bhardwaj, Mauricio Rojas, Ruhang Tang, Susan S. Smyth, Craig H. Selzman

    Plan Plan

• Pediatric Surgery

  • ·Toll-like receptor 2 (TLR2) is protective of ischemia/reperfusion mediated small bowel injury in an animal necrotizing enterocolitis (NEC) model: Possible role in developing mucosal immunity

    Page :S52

    Charles J. Aprahamian, Reed A. Dimmit, Robin G. Lorenz, Carroll M. Harmon

    Plan Plan
  • ·Intestinal epithelial cell apoptosis requires BAX activation via p38 MAP kinase

    Page :S49

    George Sheng, Brad Warner

    Plan Plan
  • ·Angiotensin-converting enzyme inhibitor reduces the severity of colitis in a mouse model

    Page :S49

    Hiroyuko Koga, Hua Yang, Xiaoyi Sun, Keisuke Nose, Daniel Teitelbaum

    Plan Plan
  • ·Factor-VII transcription correlates with hepatocyte proliferation and hepatocyte growth factor expression in a rodent extra-hepatic portal vein obstruction model

    Page :S50

    Bill Chiu, Hector Melin-Aldana, Srikumar Pillai, Fei Chu, Riccardo Superina

    Plan Plan
  • ·RNA interference of cholangiocyte expression of the alpha2beta1 integrin reduces susceptibility to rhesus rotavirus infection

    Page :S50

    Mubeen A. Jafri, Bryan Donnelly, Steve Allen, Greg Tiao

    Plan Plan
  • ·AML-1/Angiopoietin signaling contributes to hepatoblastoma recurrence during VEGF blockade

    Page :S50

    Joey C. Papa, Angela Kadenhe-Chiweshe, Kimberly McCrudden, Jianzhong Huang, Darrell Yamashiro, Jessica Kandel

    Plan Plan
  • ·Phosphatidylinositol 3-kinase regulates bombesin-induced angiogenesis and in vivo neuroblastoma growth

    Page :S51

    Dai H. Chung, Junghee Kang, Titilope Ishola, Naira Baregamian, B. Mark Evers, Dai H. Chung

    Plan Plan
  • ·Evaluation of the maternal and fetal stress response to maternal-fetal surgery

    Page :S51

    Raul A. Cortes, Mattew Clifton, Amy Wagner, Erich Grethel, Kerilyn Nobuhara, Robert Ball, Diana Farmer, Michael Harrison, Hanmin Lee

    Plan Plan
  • ·The gap junction protein connexin 43 mediates phagocytosis in vivo and is important for organism survival during sepsis

    Page :S52

    Rahul J. Anand, Rosemary Hoffman, Ryan Levy, Jun Li, Janet Fan, David Hackam

    Plan Plan
  • ·Norepinephrine negatively modulates wound macrophage phagocytic function through alpha- and beta-adrenoreceptor-dependent mechanisms

    Page :S52

    Ankush Gosain, Kuzhali Muthu, Stephen B. Jones, Richard L. Gamelli, Luisa A. DiPietro

    Plan Plan
  • ·Inhaled nitrite treats experimental pulmonary arterial hypertension

    Page :S53

    Kevin Mollen, Augustine Choi, Michael Mathier, Emeka Ifedigbo, Mark Gladwin, Brian Zuckerbraun

    Plan Plan
  • ·Innate immune barrier to the engraftment of prenatally transplanted embryonic stem cell derived hematopoietic progenitors

    Page :S53

    Aimen F. Shaaban, Lasya Gaur, Deepika Rajesh

    Plan Plan

• Plastic Surgery I

  • ·Achieving standardized quantitative and qualitative scar analysis in a fibromodulin deficient mice model

    Page :S57

    Jeremy Feasel, Khoi Nguyen, Joyce Z. Wang, Xinli Zhang, Anh Le, Benjamin Wu, Chia Soo

    Plan Plan
  • ·Comparative evaluation of adhesion formation, strength of ingrowth, and textile properties of prosthetic biomaterials at 4 months and one year after intra-abdominal implantation in a rabbit

    Page :S54

    Andrew G. Harrell, Yuri W. Novitsky, Richard D. Peindl, Marc Zerey, B. Lauren Paton, H. James Norton, Kent W. Kercher, B. Todd Heniford

    Plan Plan
  • ·Cellular response of keloid-derived keratinocytes to physical stress

    Page :S54

    Zhen Wang, Toan-Thang Phan, Ivor Lim, Michael Longaker, George Yang

    Plan Plan
  • ·BMP antagonism via noggin in adult dura mater

    Page :S55

    Matthew D. Kwan, Derrick Wan, Michael Longaker

    Plan Plan
  • ·Effects of circulating factors in diabetic wound healing

    Page :S55

    Giorgio Pietramaggiori, Saja Scherer, Michael Alperovich, Amy Wagers, Dennis Orgill

    Plan Plan
  • ·In-vivo gene silencing using topical delivery of siRNA

    Page :S55

    Vishal Thanik, Matthew Greives, Natalie Seiser, Oren Lerman, Alexes Hazen, Jamie Levine, Pierre Saadeh

    Plan Plan
  • ·Predictive model for intra-operative blood loss at initial excision and grafting in adult burn patients

    Page :S56

    Neil R. McMullin, Jingjing Wang, Steven Wolf, John Holcomb, Charlie Wade

    Plan Plan
  • ·Hyperberic oxygen protects against oxidative stress in an Ischemic wound model

    Page :S56

    Qixu Zhang, Qing Chang, Lisa Gould

    Plan Plan
  • ·Fetal wound healing using a knockout murine model: The contribution of P-selectin

    Page :S56

    Bindi Naik-Mathuria, Ling Yu, Andre Gay, Darrell Cass, C. Wayne Smith, Oluyinka Olutoye

    Plan Plan
  • ·Closure of mid-gestational excisional wounds in a novel fetal mouse model

    Page :S57

    Stephanie R. Goldberg, Robert McKinstry, David Lanning

    Plan Plan
  • ·Upregulation of WNT-4 expression in keloid fibroblasts after TGF-B1&-B3 stimulation

    Page :S57

    Anuja K. Antony, Amy Colwell, Michael T. Longaker, H. Peter Lorenz

    Plan Plan
  • ·bFGF gene transfer through AAV vectors to digital flexor tendons significantly increases healing strength: An in vivo study

    Page :S57

    Jin Bo Tang, Yi Cao, Ren Guo Xie, Bei Zhu, Xin Ke-Qin, Wang Xiao Tian, Liu Paul

    Plan Plan

• Plastic Surgery II

  • ·Treatment of abscesses in the era of methicillin resistant staphylococcus aureus–Are antibiotics necessary?

    Page :S62

    Priya M. Rajendran, David Young, Toby Maurer, Henry Chambers, Hobart Harris

    Plan Plan
  • ·Growing prevalence of panton-valentine leucocidin (PVL) within community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA)

    Page :S59

    Amarjit S. Dosanjh, Peter Ro, Keyianoosh Z. Paydar, Priya Rajendran, Diana Yu, Scott L. Hansen, Francoise Perdreau-Remington, David M. Young

    Plan Plan
  • ·Antibody mediated ischemia-reperfusion injury and peptide protection of a random dorsal flap

    Page :S59

    Jalil Afnan, Jennifer Rabaglia, Brian Williams, Sean Oakes, Michael Carroll, Francis Moore

    Plan Plan
  • ·Micro-mechanical forces stimulate cell proliferation and vascularization of perfused tissues

    Page :S60

    Giorgio Pietramaggiori, Jeffrey Rentz, Saja Scherer, Kaipainen Arja, Perry Liu, Vishal Saxena, Moritz Konerding, Dennis Orgill

    Plan Plan
  • ·Neurotization improves force in engineered skeletal muscle

    Page :S60

    Ian F. Lytle, Vikas Dhawan, Yen-Chih Huang, Tatiana Kostrominova, Ravi Birla, David Brown

    Plan Plan
  • ·Tissue engineered lymphatic vessels: A first step toward the clinical treatment of lymphedema

    Page :S60

    Alex K. Wong, Sen Li, Peter Cordeiro, Babak Mehrara

    Plan Plan
  • ·Endothelial progenitor cells participate in neovascularization and engraftment of cultured skin substitutes

    Page :S61

    Sachin S. Vaikunth, Marwan Marwan, Jignesh Parvadia, Maria Ripberger, Barbara Kalinowska, Eva Uzvolgy, Andrew Supp, Datis Alaee, Steve Boyce, Timothy Crombleholme, Dorothy Supp

    Plan Plan
  • ·Donor antigen-pulsed host dendritic cells combined with transient immunosuppression prolong hind-limb survival

    Page :S61

    Justin M. Sacks, Ryosuke Ikeguchi, Ali E. Aksu, Elaine Horibe, Jignesh Unadkat, Aurele Taieb, Jeremy Breitinger, Angus W. Thomson, Maryam Feili-Hariri, W.P. Andrew Lee

    Plan Plan
  • ·Obesity lowers tolerance to ischemia-reperfusion in the rat abdominal flap: A novel animal model for free flap breast reconstruction

    Page :S61

    Mark E. Feldmann, Ron Reyna, Seung-Jun O, Kenneth Chavin

    Plan Plan
  • ·Functional characterization of cultured cutaneous keratinocytes removed close to the inflammatory site of severely burned patients

    Page :S62

    Siegfried Zedler, Gerd Gauglitz, Maren Klein, Felix v Spiegel, Jasmin Fuhr, Guido H.v. Donnersmarck, Eugen Faist

    Plan Plan
  • ·Loco-regional infrared preconditioning improved epigastric flap survival via upregulation of heat shock protein 72 (HSP72)

    Page :S62

    Fuan Chiang Chan, Jonathan McGuinness, Richard Hanson, Brian Kneafsey, David Bouchier-Hayes

    Plan Plan
  • ·Tamoxifen induces tumour cell apoptosis, decreases proliferation and blocks metastatic invasive potential in anaplastic thyroid cancer

    Page :S62

    James P. O’Neill, Claire Condron, Ann-Marie Byrne, Michael Walsh, David Bouchier-Hayes

    Plan Plan
  • ·The effects of propofol and isoflurane on ischemia reperfusion injury in free flaps—a genomic analysis

    Page :S63

    Kevin J. Bruen, Danesh K. Gupta, Robert W. Weiss, Diane M. Dunn, Susan L. Thibeault, Scott McJames, Wenhua Li, Marga F. Massey

    Plan Plan

• Quality, Outcomes, and Costs I

  • ·African American children experience worse clinical and functional outcomes after traumatic brain injury: An analysis of the national pediatric trauma registry

    Page :S67

    Adil H. Haider, David Efron, Elliott Haut, Stephen DiRusso, Thomas Sullivan, Edward Cornwell

    Plan Plan
  • ·Relationship between hospital volume and system support in pancreatic resections

    Page :S64

    Bellal Joseph, Ilan Rubinfeld, Joseph Musial, Chadi Faraj, Vic Velanovich

    Plan Plan
  • ·Insurance status, but not race, predicts perforation in adult patients with acute appendicitis

    Page :S64

    Fredric M. Pieracci, Soumitra Eachempati, Philip S. Barie, Mark A. Callahan

    Plan Plan
  • ·Validation of administrative data for the study of gastrointestinal disease

    Page :S65

    Steven Lopushinsky, Kelina Risnyj, Linda Rabeneck, Peter Austin, David Urbach

    Plan Plan
  • ·A novel cost-benefit analysis of prophylactic octreotide for pancreatic resections

    Page :S65

    Tsafrir Vanounou, Wande Pratt, Mark Callery, Charles Vollmer

    Plan Plan
  • ·Outcomes in pediatric patients undergoing straight versus J-pouch ileoanal anastomosis: A multicenter analysis

    Page :S66

    Rupa Seetharamaiah, Antti Koivusalo, Brady West, Mikko Pakarinen, Ariel Spencer, Donald Liu, Risto Rintala, James Geiger, Ronald Hirschl, Arnold Coran, Daniel Teitelbaum

    Plan Plan
  • ·Discharge outcomes of trauma patients spending greater than 30 days in the intensive care unit

    Page :S66

    Brian M. Goodman, Adrian Ong, Laurel Omert, Elan Jeremitsky, Jack Protetch, Aurelio Rodriguez

    Plan Plan
  • ·Identifying the most important bariatric surgery quality indicators: A novel methodology

    Page :S66

    Melinda Maggard, Marcia McGory, Paul Shekelle, Clifford Ko

    Plan Plan
  • ·The effect of teaching hospital status versus volume on in-hospital outcomes in adrenalectomy patients

    Page :S67

    Angela Shoher, David C. Chang, Martha A. Zeiger, Alan P. Dackiw

    Plan Plan
  • ·Classifying cause of death after cancer surgery

    Page :S67

    Jennifer F. Waljee, Stephanie Windisch, Jonathan Finks, Sandra Wong, John Birkmeyer

    Plan Plan
  • ·Does declining CABG volume mean worse outcomes?

    Page :S67

    James W. Ogilvie, Nancy Baxter, Beth Virnig, Peter Dahlberg, Rocco Ricciardi

    Plan Plan
  • ·Comparison of patient-centered outcomes after laparoscopic nissen fundoplication performed for gastroesophageal reflux disease or paraesophageal hernia

    Page :S68

    Lisa A. Mark, Allan Okrainec, Lorenzo E. Ferri, Liane S. Feldman, Pepa Kaneva, Serge Mayrand, Gerald M. Fried

    Plan Plan

• Quality, Outcomes, and Costs II

  • ·Unplanned enterotomy or bowel resection during elective hernia repair increases complications

    Page :S72

    Stephen H. Gray, Catherine Vick, Laura Graham, Kelly Finan, Leigh Neumayer, Kiefe Catarina, Mary Hawn

    Plan Plan
  • ·Cost-effectiveness analysis of the medical and surgical treatment options for Graves disease

    Page :S69

    Kyle A. Zanocco, Cord Sturgeon, Peter Angelos

    Plan Plan
  • ·How well do electronic systems represent colorectal cancer surgery concepts? Evaluation of SNOMED-CT, ICD9-CM, and CPT-4 for content coverage

    Page :S69

    Genevieve B. Melton, Frances P. Morrison, James J. Cimino, Larissa K. Temple, Michael A. Choti, Richard D. Schulick, Susan L. Gearhart

    Plan Plan
  • ·The influence of neoadjuvant chemotherapy on surgeon practice patterns for stage II breast cancer patients

    Page :S70

    Jennifer F. Waljee, Lina Patel-Parekh, Kirby Bland, Lisa Newman

    Plan Plan
  • ·Response to neoadjuvant radiation therapy for rectal cancer improves survival

    Page :S70

    Eric T. Castaldo, C. Wright Pinson, Irene D. Feurer, Nipun Merchant

    Plan Plan
  • ·A national perspective on the decline of abdominoperineal resection for rectal cancer

    Page :S70

    Henry S. Tilney, Alexander G. Heriot, Sanjay Purkayastha, Anthony Antoniou, Paul Aylin, Paris P. Tekkis

    Plan Plan
  • ·Association of demographic and treatment variables in long-term colorectal cancer survival

    Page :S71

    B. Todd Heniford, Amy Lincourt, Kent Kercher, Andrew Stewart, Frederick Greene

    Plan Plan
  • ·Substernal thyroidectomy is associated with increased morbidity and mortality

    Page :S71

    Fredric M. Pieracci, Thomas J. Fahey

    Plan Plan
  • ·Rating the feasibility of quality indicators: Bariatric surgery pilot study

    Page :S71

    Melinda Maggard, Marcia McGory, Paul Shekelle, Clifford Ko

    Plan Plan
  • ·Resolution of obstructive sleep apnea after laparoscopic gastric bypass

    Page :S72

    Esteban Varela, Darrin Lee, Allen Sabio, Ninh Nguyen

    Plan Plan
  • ·Opinions on upper extremity reconstructive surgery in tetraplegia: Perceptions of patients and physicians

    Page :S72

    Jared Wagner, Catherine Curtin, Kevin Chung

    Plan Plan
  • ·The impact of surgical complications on survival of patients with HPB malignancies

    Page :S72

    Reza F. Saidi, Gelen Del Rosario, Vijay Mittal, Stephen ReMine, Michael Jacobs

    Plan Plan

• Surgical Education

  • ·Evaluation of resident training activities using a novel time-motion study prior to the implementation of the 80 hour work week

    Page :S77

    Lyssa N. Ochoa, Francis C. Brunicardi, Mary L. Brandt, Samir Awad

    Plan Plan
  • ·The impact of work hour restrictions on surgical resident education

    Page :S74

    Emily T. Durkin, Robert McDonald, Alejandro Munoz, David Mahvi

    Plan Plan
  • ·Assessing decision making in operative trauma: Development of a novel tool and evaluation of its utility

    Page :S74

    Tracy M. Scott, Morad Hameed, David Evans, Eric Webber, Ross Brown, Jay Doucet, Richard Simons, Ravi Sidhu

    Plan Plan
  • ·Case-based multimedia programs enhance the maturation of surgical residents’ concepts of professionalism

    Page :S75

    Anjali S. Kumar, Kelly Bullard, Terrence Liu, Alden Harken

    Plan Plan
  • ·Does leadership training improve teamwork skills among surgical residents?

    Page :S75

    Angela Shoher, David C. Chang, Pamela A. Lipsett, Julie A. Freischlag

    Plan Plan
  • ·To pimp or not to pimp: Increased interactive format for morbidity and mortality conference improves educational value and enhances resident confidence

    Page :S75

    Jose M. Prince, Raghuveer Vallabhaneni, Andrew Watson, Kenneth Lee, Steven Hughes, Brian Harbrecht, Andrew Peitzman, Timothy Billiar, Matthew Brown

    Plan Plan
  • ·Long-term outcomes of performing laboratory research during surgical residency

    Page :S76

    Charles M. Robertson, Mary Klingensmith, Craig Coopersmith

    Plan Plan
  • ·The pre-trained novice(c): Results of a proficiency-based surgical curriculum

    Page :S76

    Matthew D. Shane, Barbara J. Pettitt, Craig B. Morgenthal, C. Daniel Smith

    Plan Plan
  • ·Closing the gap in operative performance between novices and experts: Does harder mean better for laparoscopic simulator training?

    Page :S76

    Dimitrios Stefanidis, James R. Korndorffer, B. Todd Heniford, Sarah Markley, Rafael Sierra, Daniel J. Scott

    Plan Plan
  • ·Do motion analysis meaures on a simulator predict technical skill during laparoscpic surgery?

    Page :S77

    Allan Okrainec, Anthony McCluney, Melina Vassiliou, Liane S. Feldman, Gerald M. Fried

    Plan Plan
  • ·Gaze-down three-dimensional ‘open-box’ training shortens the laparoscopic learning curve

    Page :S77

    Rajesh Aggarwal, Piers Boshier, George Hanna, Ara Darzi

    Plan Plan
  • ·How best to teach endovascular skills?

    Page :S77

    Michael J. Kim, Paul Shin, Adam Doyle, Sean Hislop, Craig Nairins, Karl Illig

    Plan Plan

• Surgical Oncology I

  • ·Immunological monitoring of regulatory T cells by flow cytometry in a novel HLA Class II HER2/neu peptide vaccine clinical trial in breast cancer patients

    Page :S82

    Matthew T. Hueman, Steven Khoo, Catherine Storrer, Katie Harris, Yusuf Jama, Craig Shriver, Sathibalan Ponniah, George Peoples

    Plan Plan
  • ·Development of antibody-targeted peptide vaccines as novel reagents for combination immunotherapy in cancer patients

    Page :S79

    Elizabeth A. Mittendorf, Catherine Storrer, Craig Shriver, George Peoples, Sathibalan Ponniah

    Plan Plan
  • ·Interleukin-18 and the toll-like receptor 9 ligand CpG stimulate murine splenic natural killer dendritic cells (NKDC) to proliferate and secrete IFN-gamma

    Page :S79

    Umer Chaudhry, Peter Kingham, George Plitas, Steven Katz, Jen Stabelford, Jesse Raab, Ronald DeMatteo

    Plan Plan
  • ·Continuous delivery of IFN-beta sensitizes human gliomas to ionizing radiation

    Page :S80

    John B. Hamner, Paxton Dickson, Mostafa W. Gaber, Cathy Ng, Junfang Zhou, Andrew Davidoff

    Plan Plan
  • ·Intraperitoneal administration of a mutant herpes simplex virus (HSV) achieves systemic cytotoxicity in tumors that overexpress MEK: A novel oncolytic strategy

    Page :S80

    Jula Veerapong, Kai Bickenbach, Kerrington Smith, Hank Schmidt, Ralph Weichselbaum, Mitchell Posner

    Plan Plan
  • ·Co-stimulatory signals upregulate PD-1 expression on human T lymphocytes: Implications for cancer immunotherapy

    Page :S81

    Susan Tsai, Arnold Mixon, Shawn Farid, Mark Dudley, Suzanne Topalian

    Plan Plan
  • ·Early results of a phase I clinical trial of an Ii-Key/HER2/neu MHC Class II peptide-based vaccine in breast cancer patients

    Page :S81

    Steven Khoo, Catherine Storrer, Katie Harris, Yusuf Jama, Anna Smith, Zia Dehqanzada, James Murray, Craig Shriver, Eric von Hofe, Sathibalan Ponniah, George Peoples

    Plan Plan
  • ·Mammaglobin-A (mamA) DNA vaccination induces HLA class-I tetramer positive breast cancer specific CD8+ Cytotoxic T-lymphocytes (CTL)

    Page :S81

    Ankit Bharat, Kishore Narayanan, William Gillanders, William Chapman, T. Mohanakumar

    Plan Plan
  • ·IRF-1 mediated apoptosis is FADD and caspase 8 dependent

    Page :S82

    Michael T. Stang, Michaele Armstrong, Greg Watson, Ye Liu, Ki-Young Sung, John Yim

    Plan Plan
  • ·Identification of human colon cancer initiating cells

    Page :S82

    Catherine A. O’Brien, Aaron Pollett, Steven Gallinger, John Dick

    Plan Plan
  • ·Targeted nanoparticle imaging of angiogenic endothelial activation in premalignant neoplasia and established epithelial cancers

    Page :S83

    Robert Neumann, Krista Olson, Gregory Lanza, Samuel Wickline, Jeffrey Arbeit

    Plan Plan
  • ·A phase I/II gene therapy trial in metastatic melanoma patients

    Page :S83

    Michel Adamina, Walter P. Weber, Rachel Rosenthal, Reto Schumacher, Paul Zajac, Walter R. Marti, Rolf Huegli, Daniel Oertli, Giulio Spagnoli, Michael Heberer

    Plan Plan

• Surgical Oncology II

  • ·Colorectal adenocarcinomas have increased EGFR ligand expression

    Page :S87

    Abigail S. Caudle, Laura Caskey, H. Shelton Earp, Benjamin Calvo

    Plan Plan
  • ·p53-derived peptide inhibits human pancreatic cancer cell growth

    Page :S84

    Wilbur B. Bowne, Vadim Shtreyler, Michael Vishnevetsky, Martin Bluth, Michael Zenilman, Josef Michl, Matthew Pincus

    Plan Plan
  • ·Oncolytic herpes simplex virus-1 (NV1023) effectively treats anaplastic thyroid cancer in an orthotopic murine model

    Page :S84

    Vincent Reid, Christopher Riedl, Zhenkun Yu, Yu-Yao Huang, Yanghee Woo, Sen Li, Malgorzata Dabrowska, Vladimir Ponomarev, Yuman Fong, Richard Wong

    Plan Plan
  • ·Mechanisms of aberrant epidermal growth factor receptor signaling in the absence of EGFR gene activating mutations in pancreatic cancer patients

    Page :S85

    Ching-Wei D. Tzeng, Andrey Frolov, Natalya Frolova, Nirag C. Jhala, Andra R. Frost, J. Harrison Howard, Kyle W. Schuller, Donald J. Buchsbaum, Selwyn M. Vickers, Martin J. Heslin, J. Pablo Arnoletti

    Plan Plan
  • ·Apigenin causes growth arrest in pancreatic cancer cells through down-regulation of the replication inhibitor protein, Geminin via both transcription and ubiquitin-mediated degradation

    Page :S85

    Mohammad R. Salabat, Laleh Golkar, Xian-Zhong Ding, Michael B. Ujiki, Jill C. Pelling, Richard H. Bell, Thomas E. Adrian, Mark S. Talamonti, David J. Bentrem

    Plan Plan
  • ·Sulindac decreases N-nitrosobis(2-oxypropyl)amine-induced precancerous hepatocellular lesion formation in hamsters

    Page :S85

    Sabrina C. Wentz, Michele T. Yip-Schneider, Earl Gage, Yufang Wang, Patrick J. Klein, Eric A. Wiebke, C. Max Schmidt

    Plan Plan
  • ·Ribonucleotide reductase M2 subunit as novel target for liposarcoma

    Page :S86

    Rula C. Geha, Vicotria Wu, Penelope DeCarolis, Rachael O’Connor, JinHong Chen, Gary Schwartz, Samuel Singer

    Plan Plan
  • ·CXCR4 signaling regulates proliferation in pancreatic cancer precursors

    Page :S86

    Ryan M. Thomas, Andrew M. Lowy

    Plan Plan
  • ·Post-transcriptional Regulation of VEGF: Potential for novel therapies

    Page :S87

    Charles Cha, Abby L. Mulkeen, Peter S. Yoo, Teresa Silva, John C. Schmitz, Edward Chu, Edward Uchio

    Plan Plan
  • ·Roles of SMAC/DIABLO and NFkB in colon carcinogenesis: Effects on proliferation and apoptosis following proteasome inhibition

    Page :S87

    Sergio Huerta, Yu-Mei Hernandez, Emily Goulet, Sara Huerta-Yepez, Edward Livingston

    Plan Plan
  • ·Dasatinib (BMS-354825), a dual SRC/ABL tyrosine kinase inhibitor, inhibits tumor formation and prevents malignant ascites in a murine model of peritoneal carcinomatosis

    Page :S87

    Donald Lesslie, Nila Parikh, Ami Shah, Justin Summy, Jose Trevino, David Hong, Nicholas Donato, Francis Lee, Gary Gallick

    Plan Plan
  • ·MET overexpression in colorectal cancer (CRC) liver metastases predicts poor survival

    Page :S88

    Todd D. Francone, Chin-Tung Chen, Ron G. Landmann, Eleanor Kuntz, Zaoshi Zeng, Philip B. Paty, Martin R. Weiser

    Plan Plan

• Transplantation

  • ·STAT3 and p38 MAPK dependent VEGF production by bone marrow stem cells following stimulation with TNF or LPS

    Page :S92

    Meijing Wang, Paul Crisostomo, Keith Lillemoe, Daniel Meldrum

    Plan Plan
  • ·Effect of methylprednisolone on liver warm ischemia-reperfusion injury

    Page :S89

    Reza F. Saidi, Yeon-Jeen Chang, Steven Verb, Steven Brooks, Vijay Mittal, Michael Jacobs

    Plan Plan
  • ·Arginase blockade as a strategy to mitigate liver ischemia-reperfusion (I/R) injury

    Page :S89

    Geetha Jeyabalan, Allan Tsung, John Klune, Timothy Billiar, David Geller

    Plan Plan
  • ·Proteasome inhibitor PS-341 inhibits NFkB and ameliorates ischemia-reperfusion injury in orthotopic liver transplant (OLT) with a steatotic graft

    Page :S90

    Jane M. Liaw, Jianluo Jia, Sean C. Glasgow, Wei Liu, Krista A. Csontos, Sabarinathan Ramachandran, Thalachallour Mohanakumar, William C. Chapman

    Plan Plan
  • ·Effect of hyperbarically oxygenated-perfluorochemial (HBO-PFC) with UW solution on preservation of rat small intestine

    Page :S90

    Kazunori Inuzuka, Naoki Unno, Naoto Yamamoto, Daisuke Sagara, Minoru Suzuki, Hiroyuki Konno

    Plan Plan
  • ·An implantable bioartificial hemofilter: Ultrafiltrate volume depends on vascular density and collecting fiber surface area

    Page :S91

    Ian F. Lytle, Vikas Dhawan, Khajohn Tiranathanagul, Liandi Lou, Gregory Borschel, Evangelos Tziampazis, Deborah Buffington, Wen-Xiang Zhang, David Humes, David Brown

    Plan Plan
  • ·Beta-adrenergic receptor antagonism prior to brain death preserves myocardial function in a porcine model

    Page :S91

    Kelly M. McLean, Prakash Pandalai, Jeffrey Pearl, Shahab Akhter, Christian Bulcao, Connie Wagner, Jodie Duffy

    Plan Plan
  • ·Characterization of two small animal models for the evaluation of antibody-mediated rejection therapies in transplantation

    Page :S91

    Christopher E. Simpkins, Daniel Warren, Zhaoli Sun, Geoff Allen, Christopher Sonnenday, Sara Cooke, Raghu Chivukula, William Baldwin, Barbara Wasowska, Robert Montgomery

    Plan Plan
  • ·Alefacept (LFA3-Ig), portal venous donor specific transfusion (PVDST), and sirolimus prolong renal allograft survival in non-human primates

    Page :S92

    Kiran K. Dhanireddy, David A. Bruno, Xiaojie Zhang, Frank V. Leopardi, Lynt B. Johnson, Allan D. Kirk

    Plan Plan
  • ·xuALG-A polyclonal antibody that depletes memory T-cells

    Page :S92

    David A. Bruno, He Xu, Douglas Hale, Allan D. Kirk

    Plan Plan
  • ·Dysregulation of autoimmunity to collagen V (col-V) and development of BOS following human lung transplantation

    Page :S92

    Ankit Bharat, Ryan Fields, Elbert Trulock, William Chapman, G. Alexander Patterson, T. Mohanakumar

    Plan Plan

• Urology/Reproductive Biology

  • ·Novel steroscopic information overlay enhances robotic endourology

    Page :S97

    Eric Hanly, Barry Herman, Noah Schenkman, Russell Taylor, Mark Talamini, Ozanan Meireles, Samuel Shih, Michael Marohn

    Plan Plan
  • ·Volumetric 3D magnetic resonance urography: A new imaging modality that enhances the diagnosis of various conditions in pediatric urology

    Page :S94

    Paul Kokorowski, Steven Kim, Hollie Jackson, Rex Moats, Lee Schiel, Dawn Berkeley, Roger De Filippo

    Plan Plan
  • ·Phosphodiesterase V inhibitors do not cause depressed macrophage TNF production

    Page :S94

    George Wairiuko, Christine Herring, Meijing Wang, Kirstan Meldrum, Paul Crisostomo, Daniel Meldrum

    Plan Plan
  • ·A retrospective review of solid epididymal masses evaluated by scrotal sonography with pathologic and clinical correlation

    Page :S95

    Ajay Nehra, Wade Alleman, Bernard King, Dirk Larson, John Cheville

    Plan Plan
  • ·Quantitative fluorescence imaging analysis (QFIA) of manganese superoxide dismutase (MnSOD) and 4-hydroxy-2-nonenal (HNE)-protein adducts in a mouse model of chronic bacterial prostatitis

    Page :S95

    Tony Mammen, George Casale, George Hemstreet, Jennifer Tian, Nizar Wehbi

    Plan Plan
  • ·Does inflammation on prostate needle biopsy increase the likelihood of cancer on subsequent biopsy?

    Page :S95

    William W. Bassett, Jane M. Lewis, Daniel M. Bettendorf, Kevin R. Loughlin

    Plan Plan
  • ·Prostate volume determines efficacy of saturation prostate biopsy

    Page :S96

    Kamran Sajadi, Tim Kim, Ronald Lewis, Martha Terris

    Plan Plan
  • ·Utility of repeat transrectal ultrasound guided prostate needle biopsies in prostate cancer detection

    Page :S96

    Jane M. Lewis, Daniel Bettendorf, Keven Loughlin

    Plan Plan
  • ·Arginine deprivation therapy as a novel treatment for prostate cancer

    Page :S96

    Tawnya L. Bowles, Joseph Galante, Colin Parsons, Subbulakshmi Virudachalam, Regina Gandour-Edwards, Richard Bold

    Plan Plan
  • ·The impact of race and gender in patients undergoing radical cystectomy for bladder cancer

    Page :S97

    Adam Hickerson, Erik Kouba, Eric Wallen, Raj Pruthi

    Plan Plan
  • ·West Virginia University deflux experience and the utility of an intra-operative cystogram with a simulated voiding phase

    Page :S97

    Adam Perlmutter, William Tarry

    Plan Plan
  • ·Watchful waiting experience for solid renal masses: insight into the natural history of incidentalomas

    Page :S97

    Daniel McRackan, Erik Kouba, Eric Wallen, Raj Pruthi

    Plan Plan
  • ·Technique of percutaneous, CT-guided radiofrequency ablation of small renal lesions under conscious sedation

    Page :S98

    Jorge Arzola, Steven M. Baughman, Jay T. Bishoff, Javier Hernandez

    Plan Plan
  • ·Peripheral temperature monitoring for laparoscopic and CT-guided radio frequency ablation of renal masses

    Page :S98

    Robert I. Carey, Leveillee Raymond, Bird Vincent

    Plan Plan

• Vascular Surgery I

  • ·TGF-beta/Smad3-induced production of CTGF by medial smooth muscle cells mediates remodeling behavior in adventitial fibroblasts

    Page :S102

    Rishi Kundi, Evan Ryer, Kamiya Kentaro, Bo Liu, K. Craig Kent

    Plan Plan
  • ·Enhanced sphingosine-1-phosphate mediated smooth muscle cell migration in metabolic syndrome is redox dependent

    Page :S99

    Andrew M. Bakken, Elisa Roztocil, Suzanne M. Nicholl, Mark G. Davies

    Plan Plan
  • ·Aged mice have impaired angiogenesis but not mitochondrial dysfunction after severe limb ischemia

    Page :S99

    Tormod S. Westvik, Stephen Maloney, Fabio Kudo, Akihito Muto, Jose Leite, Alan Dardik

    Plan Plan
  • ·Optimization of rapid silencing RNA transfection of human vein bypass grafts

    Page :S100

    Nicholas D. Andersen, Thomas Monahan, Leena Pradhan, Monica Jain, Sheng-Qian Wu, Christiane Ferran, Frank LoGerfo

    Plan Plan
  • ·Diabetes induces impaired endothelial progenitor cell mobilization that is significantly reversed under hyperoxic conditions

    Page :S100

    Katherine A. Gallagher, Lee Goldstein, April Nedeau, Donald Buerk, Stephen Thom, Omaida Velazquez

    Plan Plan
  • ·Delta-like ligand-4 induces angiogenesis at sites of neovascularization in the adult

    Page :S100

    Ram Kumar Subramanyan, Loubna Hassanieh, Jasbir Singh, Parkash Gill, Fred Weaver

    Plan Plan
  • ·Altered inflammation increases intramuscular fat accumulation and impairs skeletal muscle regeneration following ischemic injury in CCR2−/− mice

    Page :S101

    Oscar Ochoa, Paula K. Shireman, Linda M. McManus

    Plan Plan
  • ·Fetal artery healing: Changes in IL-8 gene expression may not explain lack of acute inflammation

    Page :S101

    Jean E. Hsu, Roma Patel, Oluyinka O. Olutoye, C. Wayne Smith, Darrell L. Cass

    Plan Plan
  • ·The mTOR inhibitor rapamycin inhibits proadhesive activity of arterial intimal smooth muscle cells

    Page :S102

    J. Daniel Day, Jeffery L. Walding, Benjamin Christie, Jing Kang, Martin L. Dalton, Zhongbiao Wang

    Plan Plan
  • ·IL-1 signaling in the early vein graft—Impact of IL-1 type I receptor deficiency

    Page :S102

    Peng Yu, Zhihua Jiang, Ming Tao, Scott A. Berceli, C. Keith Ozaki

    Plan Plan
  • ·In vivo evaluation of a magnetic stent based drug delivery system

    Page :S102

    Zachary G. Forbes, Frederick R. Stoddard, Shami Jagtap, David Hansberry, Benjamin B. Yellen, Kenneth A. Barbee, Gennady Friedman, Ari D. Brooks

    Plan Plan
  • ·AneuMastat(R) prevents aneurysm formation in a murine model of abdominal aortic aneurysm (AAA)

    Page :S103

    Charles Y. Ro, Royd Fukumoto, Joseph J. DeRose, Sean W. Ryan, Dan Sagalovich, Peter Collin, George J. Todd, M. David Tilson

    Plan Plan

• Vascular Surgery II

  • ·Nitric oxide inhibits the 26S proteasome in six cell types important in the vasculature

    Page :S107

    Muneera R. Kapadia, Oliver Aalami, Qun Jiang, Adam Elhofy, Melina Kibbe

    Plan Plan
  • ·The role of the MyD88 pathway in arterial remodeling

    Page :S104

    Matthew M. McRae, Amy Gallo, Ahmad Saad, Madison Cuffy, George Tellides

    Plan Plan
  • ·Upregulated expression of mineralocorticoid receptor (MR) in vein grafts: A potential role for aldosterone signaling in vein graft disease

    Page :S104

    Richard Bafford, Xin Xin, Min Park, Jose Romero, Gail Adler, Gordon Williams, Raouf Khalil, Michael Conte

    Plan Plan
  • ·Shear stress induces endothelial cell phenotype in human adipose-derived adult stem cells

    Page :S105

    Lauren J. Fischer, Alice E. Lee, Christopher DiMatteo, Negar Golesorkhi, Clinton Wrigley, Avi Galler, Thomas Tulenko, Paul DiMuzio

    Plan Plan
  • ·Ethyl pyruvate prevents ATP depletion and ameliorates inflammation in a murine model of hind-limb ischemia and reperfusion

    Page :S105

    Robert S. Crawford, Hassan Albadawi, Marvin D. Atkins, John J. Jones, Mitchell P. Fink, Michael T. Watkins

    Plan Plan
  • ·Blood as a reservoir for the vasoprotective actions of carbon monoxide

    Page :S105

    Mark W. Hennon, Brett Ozanich, Edith Tzeng

    Plan Plan
  • ·Calcium-channel blockers and beta-blockers are associated with decreased atherosclerotic plaque size and altered morphology

    Page :S106

    Matthew J. Eagleton, Paul Bishop, James Bena, Sean Nassoiy, Daniel Clair, Vikram S. Kashyap, Kenneth Ouriel

    Plan Plan
  • ·Helicobacter pylori antibody causes endothelial dysfunction and decreases eNOS expression

    Page :S106

    Nasim Hedayati, Hong Chai, Lyssa Ochoa, Peter Lin, Alan Lumsden, Qizhi Yao, Changyi Chen

    Plan Plan
  • ·Very-low-dose radiation is associated with improved MMP-9-dependent reperfusion in ischemic mouse hindlimbs

    Page :S106

    Joseph Glaser, Mark Hobeika, Jhenrong Qiao, Mary Lou Devitt, Silvia Formenti, Elizabeth Gagne, Peter Brooks, Paul Gagne

    Plan Plan
  • ·Controlled angiogenesis by FACS-purified engineered myoblast populations expressing homogeneous VEGF levels

    Page :S107

    Heidi Misteli, Roberto Gianni-Barrera, Philipp Fueglistaler, Daniel Oertli, Andrea Banfi, Michael Heberer

    Plan Plan
  • ·Lifelong limb salvage (LLS)—A more useful measure of outcome for arterial reconstructive procedures

    Page :S107

    Thomas S. Monahan, Allen Hamdan, Frank LoGerfo, Suzanne Szwarc, Nicholas Andersen, Haig Panossian, David Campbell, Sherry Scovell, Marc Schermerhorn, Frank Pomposelli

    Plan Plan
  • ·Heparin inhibits hydrogen peroxide-induced apoptosis in vascular endothelial cells through inhibiting induction of p53

    Page :S107

    William N. Veale

    Plan Plan