Sommario

• • ·Table of Contents

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• • ·Editorial Board

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• • ·Information for Readers

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• Trial Designs

  • ·Extended antiplatelet therapy with clopidogrel alone versus clopidogrel plus aspirin after completion of 9- to 12-month dual antiplatelet therapy for acute coronary syndrome patients with both high bleeding and ischemic risk. Rationale and design of the OPT-BIRISK double-blinded, placebo-controlled randomized trial

    Pagina :1-7

    Yi Li, Quanmin Jing, Bing Wang, Xiaozeng Wang, Jing Li, Shubing Qiao, Shaoliang Chen, Dominick J. Angiolillo, Yaling Han

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  • ·Optimal antiplatelet therapy for prevention of gastrointestinal injury evaluated by ANKON magnetically controlled capsule endoscopy: Rationale and design of the OPT-PEACE trial

    Pagina :8-16

    Yi Li, Xiaozeng Wang, Dan Bao, Zhuan Liao, Jing Li, Xiao Han, Heyang Wang, Kai Xu, Zhaoshen Li, Gregg W. Stone, Yaling Han

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  • ·Rationale and design of a prospective, randomized, controlled, multicenter study to evaluate the safety and efficacy of transcatheter heart valve replacement in female patients with severe symptomatic aortic stenosis requiring aortic valve intervention (Randomized researcH in womEn all comers wIth Aortic stenosis [RHEIA] trial)

    Pagina :27-35

    Helene Eltchaninoff, Nikolaos Bonaros, Bernard Prendergast, Fabian Nietlispach, Mariuca Vasa-Nicotera, Alaide Chieffo, Philippe Pibarot, Peter Bramlage, Lenka Sykorova, Jana Kurucova, Jeroen J. Bax, Stephan Windecker, Nicolas Dumonteil, Didier Tchetche

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  • ·The act on evascularization utcomes of intraascular ultrasound-guided treatment of complex lesions and conomic impact (IMPROVE) trial: Study design and rationale

    Pagina :65-71

    Evan Shlofmitz, Rebecca Torguson, Gary S. Mintz, Cheng Zhang, Andrew Sharp, John McB. Hodgson, Binita Shah, Gautam Kumar, Jasvindar Singh, Becky Inderbitzen, William S. Weintraub, Hector M. Garcia-Garcia, Carlo Di Mario, Ron Waksman

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  • ·Comparison of optical coherence tomography–guided versus intravascular ultrasound–guided percutaneous coronary intervention: Rationale and design of a randomized, controlled OCTIVUS trial

    Pagina :72-80

    Do-Yoon Kang, Jung-Min Ahn, Hanbit Park, Pil Hyung Lee, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Sang-Wook Kim, Seung-Ho Hur, Yun-Kyeong Cho, Cheol Hyun Lee, Soon Jun Hong, Young Joon Hong, Young Won Yoon, Soo-Joong Kim, Jang-Ho Bae, Jun-Hyok Oh, Duk-Woo Park, Seung-Jung Park

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  • ·RHAPSODY: Rationale for and design of a pivotal Phase 3 trial to assess efficacy and safety of rilonacept, an interleukin-1? and interleukin-1? trap, in patients with recurrent pericarditis

    Pagina :81-90

    Allan L. Klein, Massimo Imazio, Antonio Brucato, Paul Cremer, Martin LeWinter, Antonio Abbate, David Lin, Alberto Martini, Anna Beutler, Steven Chang, Fang Fang, Anais Gervais, Randy Perrin, John F. Paolini

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  • ·Rationale and design of the MULTISTARS AMI Trial: A randomized comparison of immediate versus staged complete revascularization in patients with ST-segment elevation myocardial infarction and multivessel disease

    Pagina :98-108

    Barbara E. Stähli, Ferdinando Varbella, Bettina Schwarz, Peter Nordbeck, Stephan B. Felix, Irene M. Lang, Aurel Toma, Marco Moccetti, Christian Valina, Matteo Vercellino, Angelos G. Rigopoulos, Miklos Rohla, Matthias Schindler, Manfred Wischnewsky, Axel Linke, P. Christian Schulze, Gert Richardt, Karl-Ludwig Laugwitz, Franz Weidinger, Wolfgang Rottbauer, Stephan Achenbach, Kurt Huber, Franz-Josef Neumann, Adnan Kastrati, Ian Ford, Frank Ruschitzka, Willibald Maier, on behalf of the MULTISTARS AMI Investigators

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• Clinical Investigations

  • ·Smartphone-based application to improve medication adherence in patients after surgical coronary revascularization

    Pagina :17-26

    Chunyu Yu, Chongyang Liu, Junzhe Du, Hanning Liu, Heng Zhang, Yan Zhao, Limeng Yang, Xi Li, Jing Li, Jue Wang, Huishan Wang, Zhigang Liu, Chenfei Rao, Zhe Zheng, for the MISSION-2 Collaborative Group

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  • ·Comparison of a new 3-item self-reported measure of adherence to medication with pharmacy claims data in patients with cardiometabolic disease

    Pagina :36-43

    Julie C. Lauffenburger, Constance P. Fontanet, Thomas Isaac, Chandrasekar Gopalakrishnan, Thomas D. Sequist, Joshua J. Gagne, Cynthia A. Jackevicius, Michael A. Fischer, Daniel H. Solomon, Niteesh K. Choudhry

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  • ·Twelve weeks of treatment with empagliflozin in patients with heart failure and reduced ejection fraction: A double-blinded, randomized, and placebo-controlled trial

    Pagina :47-56

    Jesper Jensen, Massar Omar, Caroline Kistorp, Mikael Kjær Poulsen, Christian Tuxen, Ida Gustafsson, Lars Køber, Finn Gustafsson, Jens Faber, Emil L Fosbøl, Niels Eske Bruun, Jan Christian Brønd, Julie Lyng Forman, Lars Videbæk, Jacob Eifer Møller, Morten Schou

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  • ·Outcomes of transcatheter aortic valve replacement for patients with severe aortic stenosis and concomitant aortic insufficiency: Insights from the TVT Registry

    Pagina :57-64

    Bhaskar Bhardwaj, David J Cohen, Sreekanth Vemulapalli, Andrzej S Kosinski, Qun Xiang, Zhuokai Li, Keith B. Allen, Samir Kapadia, Kul Aggarwal, Paul Sorajja, Adnan K. Chhatriwalla

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  • ·Outcomes following revascularization with radial artery bypass grafts: Insights from the PREVENT-IV trial

    Pagina :91-97

    Oliver K. Jawitz, Morgan L. Cox, David Ranney, Judson B. Williams, Hillary Mulder, Mario F.L. Gaudino, Stephen Fremes, Robert H. Habib, C. Michael Gibson, Thomas A. Schwann, Renato D. Lopes, John H. Alexander

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  • ·New-generation drug-eluting coronary stents in octogenarians: Patient-level pooled analysis from the TWENTE I-IV trials

    Pagina :109-115

    Eline H. Ploumen, Rosaly A. Buiten, Carine J.M. Doggen, Martin G. Stoel, K. Gert van Houwelingen, Carl E. Schotborgh, Gillian A.J. Jessurun, Ariel Roguin, Peter W. Danse, Edouard Benit, Adel Aminian, Gerard C.M. Linssen, Frits H.A.F. de Man, Marc Hartmann, Diedrik G. Buiten, Marlies M. Kok, Paolo Zocca, Clemens von Birgelen, on behalf of the TWENTE I-IV trial investigators

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• Research Letters

  • ·Prevalence of angina and use of medical therapy among US adults: A nationally representative estimate

    Pagina :44-46

    Rahul Aggarwal, Nicholas Chiu, Varayini Pankayatselvan, Changyu Shen, Robert Yeh

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• Letter to the Editors

  • ·Letter to the editor regarding the study “Impact of time of onset of symptom of ST-segment elevation myocardial infarction on 1-year rehospitalization for heart failure and mortality” published in the American Heart Journal

    Pagina :116

    Nora Rossberg, Ali Kirresh, Mahmood Ahmad

    
  • ·Response to the letter to the editor regarding the study “Impact of time of onset of symptom of ST-segment elevation myocardial infarction on 1-year rehospitalization for heart failure and mortality” published in the American Heart Journal

    Pagina :117-118

    Valeria Paradies, Huili Zheng, Heerajnarain Bulluck, Derek J. Hausenloy