Sommario

• • ·Cover 1

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• • ·Brief Overview of This Month's JACI

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• • ·Table of Contents

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• • ·Editorial Board

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• Reader services

  • ·Information for Readers

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  • ·News & Notes-AAAAI

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  • ·CME Calendar-AAAAI

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• Reviews and feature articles

  • ·Dendritic cells in food allergy, treatment, and tolerance

    Pagina :511-522

    Elise G. Liu, Xiangyun Yin, Emily R. Siniscalco, Stephanie C. Eisenbarth

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  • ·Circulating innate lymphoid cells (cILCs): Unconventional lymphocytes with hidden talents

    Pagina :523-536

    Sabrina B. Bennstein, Markus Uhrberg

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• The Editors' choice

  • ·The Editors’ Choice

    Pagina :537-543

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• News beyond our pages

  • ·News beyond our pages - September 2024

    Pagina :544-545

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• Editorials

  • ·Sputum eosinophil peroxidase: Building a better biomarker for eosinophilic asthma

    Pagina :546-548

    Steven J. Ackerman

     
  • ·Mast cell β1 integrin localizes mast cells in close proximity to blood vessels and enhances their rapid responsiveness to intravenous antigen

    Pagina :549-551

    Stephen J. Galli

     
  • ·When Dumbo meets IKAROS: Fear and hubris

    Pagina :552-553

    V. Koneti Rao

     
  • ·“Where are they now?” Catching up with the 2019 AAAAI Faculty Development Awardees

    Pagina :554-556

    Zuhair K. Ballas

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• Asthma and lower airway disease

  • ·Downregulation of otulin induces inflammasome activation in neutrophilic asthma

    Pagina :557-570

    Quang Luu Quoc, YeJi Kim, Gunwoo Park, Thi Bich Tra Cao, Youngwoo Choi, Yong Hwan Park, Hae-Sim Park

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  • ·A novel syndrome of silent rhinovirus-associated bronchoalveolitis in children with recurrent wheeze

    Pagina :571

    W. Gerald Teague, Cameron D. Griffiths, Kelly Boyd, Stella C. Kellams, Monica Lawrence, Thomas L. Offerle, Peter Heymann, William Brand, Ariana Greenwell, Jeremy Middleton, Kristin Wavell, Jacqueline Payne, Marthajoy Spano, Elaine Etter, Brittany Wall, Larry Borish

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  • ·Utility of eosinophil peroxidase as a biomarker of eosinophilic inflammation in asthma

    Pagina :580

    Monica Tang, Annabelle R. Charbit, Mats W. Johansson, Nizar N. Jarjour, Loren C. Denlinger, Wilfred W. Raymond, Michael C. Peters, Eleanor M. Dunican, Mario Castro, Kaharu Sumino, Serpil C. Erzurum, Suzy A. Comhair, Wendy C. Moore, Bruce D. Levy, Elliot Israel, Wanda Phipatanakul, Brenda R. Phillips, David T. Mauger, Eugene R. Bleecker, Sally E. Wenzel, Merritt L. Fajt, Prescott G. Woodruff, Annette T. Hastie, John V. Fahy, National Heart Lung and Blood Institute Severe Asthma Research Program

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  • ·ALOX15⁺ M2 macrophages contribute to epithelial remodeling in eosinophilic chronic rhinosinusitis with nasal polyps

    Pagina :592-608

    Chang Liu, Kanghua Wang, Wenqin Liu, Jinxiu Zhang, Yunping Fan, Yueqi Sun

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  • ·Investigation of lactotransferrin messenger RNA expression levels as an anti–type 2 asthma biomarker

    Pagina :609-618

    Nicholas C. Li, Natalie Iannuzo, Stephanie A. Christenson, Paul R. Langlais, Monica Kraft, Julie G. Ledford, Xingnan Li

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• Rhinitis, sinusitis, and ocular allergy

  • ·Nasal brushing molecular endotyping distinguishes patients with chronic rhinosinusitis with nasal polyps with better response to dupilumab

    Pagina :619-630

    Kaitlyn Gayvert, Martin Desrosiers, Tanya M. Laidlaw, Leda P. Mannent, Kiran Patel, Julie Horowitz, Nikhil Amin, Alexandre Jagerschmidt, Jennifer D. Hamilton, Wei Keat Lim, Sivan Harel

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  • ·The nasal basal cell population shifts toward a diseased phenotype with impaired barrier formation capacity in allergic rhinitis

    Pagina :631-643

    Emma Ruysseveldt, Brecht Steelant, Tine Wils, Jonathan Cremer, Dominique M.A. Bullens, Peter W. Hellings, Katleen Martens

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  • ·SIRT5 exacerbates eosinophilic chronic rhinosinusitis by promoting polarization of M2 macrophage

    Pagina :644-656

    Xu-Dong Cha, Qing-Yun Zou, Feng-Zhen Li, Tian-Yu Wang, Sheng-Lei Wang, Bo-Yu Cai, Zhi-Wen Cao, Zhen-Hua Ji, Hai-Bin Liu, Wen-Wen Wang, Teng-Fei Li, Cai-Quan Liang, Wen-Wen Ren, Huan-Hai Liu

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• Atopic dermatitis and inflammatory skin disease

  • ·A genome-wide meta-analysis of palmoplantar pustulosis implicates T_H2 responses and cigarette smoking in disease pathogenesis

    Pagina :657

    Ariana Hernandez-Cordero, Laurent Thomas, Alice Smail, Zhao Qin Lim, Jake R. Saklatvala, Raymond Chung, Charles J. Curtis, Patrick Baum, Sudha Visvanathan, A. David Burden, Hywel L. Cooper, Giles Dunnill, Christopher E.M. Griffiths, Nick J. Levell, Richard Parslew, Nick J. Reynolds, Shyamal Wahie, Richard B. Warren, Andrew Wright, APRICOT and PLUM Study Team, Michael Simpson, Kristian Hveem, Jonathan N. Barker, Nick Dand, Mari Løset, Catherine H. Smith, Francesca Capon, Thamir Abraham, Muhmad Ali, Suzannah August, David Baudry, Gabrielle Becher, Anthony Bewley, Victoria Brown, Victoria Cornelius, Sharizan Ghaffar, John Ingram, Svetlana Kavakleiva, Susan Kelly, Mohsen Khorshid, Helen Lachmann, Effie Ladoyanni, Helen McAteer, John McKenna, Freya Meynell, Prakash Patel, Andrew Pink, Kingsley Powell, Angela Pushparajah, Catriona Sinclair, Rachel Wachsmuth

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  • ·Genetically proxied IL-6 receptor inhibition is associated with increased risk of atopic dermatitis

    Pagina :666-669

    Sizheng Steven Zhao, Zenas Z.N. Yiu

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  • ·Urinary eicosanoid levels in early life and risk of atopic disease in childhood

    Pagina :670-678

    Liang Chen, Nicklas Brustad, Min Kim, Yang Luo, Tingting Wang, Mina Ali, Nicole Prince, Yulu Chen, Su Chu, Sofina Begum, Kevin Mendez, Rachel S. Kelly, Ann-Marie Schoos, Morten A. Rasmussen, Javier Zurita, Johan Kolmert, Jakob Stokholm, Augusto Litonjua, Scott T. Weiss, Klaus Bønnelykke, Craig E. Wheelock, Jessica Lasky-Su, Bo Chawes

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• Food allergy and gastrointestinal disease

  • ·New light on an old syndrome: Role of Api g 7 in mugwort pollen–related celery allergy

    Pagina :679

    Barbara K. Ballmer-Weber, Andrea Wangorsch, Peter Bures, Kay-Martin Hanschmann, Gabriele Gadermaier, Lars Mattsson, Clare E.N. Mills, Ronald van Ree, Jonas Lidholm, Stefan Vieths

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  • ·Saliva antibody profiles are associated with reaction threshold and severity of peanut allergic reactions

    Pagina :690

    Hsi-en Ho, Zoe Arditi, Lin Radigan, Galina Grishina, Lingdi Zhang, Yoojin Chun, Tracy Lo, Julie Wang, Scott Sicherer, Supinda Bunyavanich

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• Anaphylaxis, drug allergy, urticaria, and angioedema

  • ·DAB2IP associates with hereditary angioedema: Insights into the role of VEGF signaling in HAE pathophysiology

    Pagina :698-706

    Maria D'Apolito, Rosa Santacroce, Daniel Osvaldo Vazquez, Giorgia Cordisco, Claudio Agustin Fantini, Giovanna D'Andrea, Angelica Leccese, Anna Laura Colia, Pablo Martinez, Andrea Zanichelli, Darío Josviack, Maurizio Margaglione

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  • ·Nasal solitary chemosensory cells govern daily rhythm in mouse model of allergic rhinitis

    Pagina :707-718

    Haiman Xu, Lianxia Guo, Tingying Hao, Xiaocao Guo, Meiping Huang, Haobin Cen, Min Chen, Jiaxian Weng, Meixia Huang, Zicong Wu, Zifei Qin, Jing Yang, Baojian Wu

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  • ·IL-4–STAT6 axis amplifies histamine-induced vascular endothelial dysfunction and hypovolemic shock

    Pagina :719-734

    James Krempski, Amnah Yamani, Lakshmi Narasimha Rao Thota, Sahiti Marella, Varsha Ganesan, Ankit Sharma, Atsunori Kaneshige, Longchuan Bai, Haibin Zhou, Paul S. Foster, Shaomeng Wang, Andrea T. Obi, Simon P. Hogan

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• Biologics and immunotherapy

  • ·A pediatric randomized, controlled trial of German cockroach subcutaneous immunotherapy

    Pagina :735

    Edward Zoratti, Robert Wood, Anna Pomés, Ricardo Da Silva Antunes, Matthew C. Altman, Basilin Benson, Lisa M. Wheatley, Kate Cho, Agustin Calatroni, Frederic F. Little, J. Pongracic, Melanie Makhija, Gurjit K. Khurana Hershey, Michael G. Sherenian, Katherine Rivera-Spoljaric, Jeffrey R. Stokes, Michelle A. Gill, Rebecca S. Gruchalla, Jeffrey Chambliss, Andrew H. Liu, Meyer Kattan, Paula J. Busse, Leonard B. Bacharier, William Sheehan, Haejin. Kim, Jill Glesner, Peter J. Gergen, Alkis Togias, Jessica L. Baucom, Cynthia M. Visness, Alessandro Sette, William W. Busse, Daniel J. Jackson, Inner-City Asthma and Childhood Asthma in Urban Settings Consortia

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• Mechanisms of allergy/immunology

  • ·Integrin β1–mediated mast cell immune-surveillance of blood vessel content

    Pagina :745-753

    Kristina Link, Lina Muhandes, Anastasia Polikarpova, Tim Lämmermann, Michael Sixt, Reinhard Fässler, Axel Roers

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• Translational and clinical immunology

  • ·Clinical and humoral response after SARS-CoV-2 breakthrough infection in patients receiving immunosuppressant therapy

    Pagina :754

    Eileen W. Stalman, Luuk Wieske, Jim B.D. Keijser, Koos P.J. van Dam, Laura Y.L. Kummer, Maarten F. Wilbrink, Zoé L.E. van Kempen, Joep Killestein, Adriaan G. Volkers, Sander W. Tas, Laura Boekel, Gerrit J. Wolbink, Anneke J. van der Kooi, Joost Raaphorst, Mark Löwenberg, R. Bart Takkenberg, Geert R.A.M. D’Haens, Phyllis I. Spuls, Marcel W. Bekkenk, Annelie H. Musters, Nicoline F. Post, Angela L. Bosma, Marc L. Hilhorst, Yosta Vegting, Frederique J. Bemelman, Alexandre E. Voskuyl, Bo Broens, Agner Parra Sanchez, Cécile A.C. M. van Els, Jelle de Wit, Abraham Rutgers, Karina de Leeuw, Barbara Horváth, Jan J.G.M. Verschuuren, Annabel M. Ruiter, Lotte van Ouwerkerk, Diane van der Woude, Renée C.F. Allaart, Y.K. Onno Teng, Pieter van Paassen, Matthias H. Busch, Esther Brusse, Pieter A. van Doorn, Adája E. Baars, Dirkjan Hijnen, Corine R.G. Schreurs, W. Ludo van der Pol, H. Stephan Goedee, Maurice Steenhuis, Sofie Keijzer, Olvi Cristianawati, Anja ten Brinke, Niels J.M. Verstegen, Koos A.H. Zwinderman, S. Marieke van Ham, Theo Rispens, Matthijs R. Welkers, Marcel Jonges, Filip Eftimov, Taco W. Kuijpers, T2B! immunity against SARS-CoV-2 study group

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  • ·L-plastin associated syndrome of immune deficiency and hematologic cytopenia

    Pagina :767-777

    Raquel A. Hernandez, James I. Hearn, Vijay Bhoopalan, Abdul Rezzak Hamzeh, Kristy Kwong, Koula Diamand, Ainsley Davies, Fei-Ju Li, Harish Padmanabhan, Rachel Milne, Fiona Ballard, Dominik Spensberger, Elizabeth E. Gardiner, Bahar Miraghazadeh, Anselm Enders, Matthew C. Cook

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  • ·The common variable immunodeficiency IgM repertoire narrowly recognizes erythrocyte and platelet glycans

    Pagina :778

    Carole Le Coz, Melissa Trofa, Dorothy L. Butler, Samuel Yoon, Tian Tian, Whitney Reid, Emylette Cruz Cabrera, Ainsley V.C. Knox, Caroline Khanna, Kathleen E. Sullivan, Jennifer Heimall, Patricia Takach, Olajumoke O. Fadugba, Monica Lawrence, Soma Jyonouchi, Hakon Hakonarson, Andrew D. Wells, Steven Handler, Karen B. Zur, Vinodh Pillai, Jeffrey C. Gildersleeve, Neil Romberg

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  • ·Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration

    Pagina :792-806

    Fang Yu, Satanay Hubrack, Christophe M. Raynaud, Asha Elmi, Rafah Mackeh, Nourhen Agrebi, Gaurav Thareja, Abdelaziz Belkadi, Hesham Al Saloos, Ayeda Abdulsalam Ahmed, Saleema C. Purayil, Yasmin A. Mohamoud, Karsten Suhre, Charbel Abi Khalil, Frank Schmidt, Bernice Lo, Amel Hassan, Khaled Machaca

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  • ·Whole blood transcriptome in long-COVID patients reveals association with lung function and immune response

    Pagina :807-818

    Jelle M. Blankestijn, Nadia Baalbaki, Somayeh Bazdar, Inés Beekers, Rosanne J.H.C.G. Beijers, Joop P. van den Bergh, Lizan D. Bloemsma, Merel E.B. Cornelissen, Tamara Dekker, Jan Willem Duitman, Laura Houweling, John J.L. Jacobs, Ivo van der Lee, Paulien M.A. Linders, Lieke C.E. Noij, Esther J. Nossent, Marianne A. van de Pol, Brigitte M. Sondermeijer, J.J. Miranda Geelhoed, Els J.M. Weersink, Korneliusz Golebski, Mahmoud I. Abdel-Aziz, Anke H. Maitland-van der Zee, P4O2 Consortium

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• Brief reports

  • ·IgG4-related disease and B-cell malignancy due to an IKZF1 gain-of-function variant

    Pagina :819-826

    Blanca García-Solís, María Tapia-Torres, Ana García-Soidán, Elisa Hernández-Brito, María Teresa Martínez-Saavedra, José M. Lorenzo-Salazar, Sonia García-Hernández, Ana Van Den Rym, Karan Mayani, José Vicente Govantes-Rodríguez, Adrian Gervais, Paul Bastard, Anne Puel, Jean-Laurent Casanova, Carlos Flores, Rebeca Pérez de Diego, Carlos Rodríguez-Gallego

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  • ·Impaired high-density lipoprotein function and endothelial barrier stability in severe anaphylaxis

    Pagina :827-832

    Sergio Fernandez-Bravo, Marina Canyelles, Ariadna Martín-Blázquez, Carla Borràs, Emilio Nuñez-Borque, Lucia Palacio-García, Pablo Rodríguez Del Rio, Diana Betancor, Alicia Gómez-López, Marina Sabaté Brescó, José Julio Laguna, Nerea Méndez-Barbero, Noemi Rotllan, Joan Carles Escolà-Gil, Vanesa Esteban

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  • ·Corrigendum

    Pagina :833