Sommario

• Editorial

  • ·Where Do We Go from Here?

    Pagina :188-189

    Ronald C. Petersen

    Mappa Mappa
  • ·The ‘Aducanumab Story’: Will the Last Chapter Spell the End of the ‘Amyloid Hypothesis’ or Mark a New Beginning?

    Pagina :190-192

    Zaven S. Khachaturian

    
  • ·Aducanumab Trials EMERGE But Don’t ENGAGE

    Pagina :193-196

    Lon S. Schneider

    Mappa Mappa

• Original Research

  • ·Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease

    Pagina :197-210

    Samantha Budd Haeberlein, P.S. Aisen, F. Barkhof, S. Chalkias, T. Chen, S. Cohen, G. Dent, O. Hansson, K. Harrison, C. von Hehn, T. Iwatsubo, C. Mallinckrodt, C.J. Mummery, K.K. Muralidharan, I. Nestorov, L. Nisenbaum, R. Rajagovindan, L. Skordos, Y. Tian, C.H. van Dyck, B. Vellas, S. Wu, Y. Zhu, A. Sandrock

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• Review

  • ·Detection and Management of Amyloid-Related Imaging Abnormalities in Patients with Alzheimer’s Disease Treated with Anti-Amyloid Beta Therapy

    Pagina :211-220

    Jerome Barakos, D. Purcell, J. Suhy, S. Chalkias, P. Burkett, C. Marsica Grassi, C. Castrillo-Viguera, I. Rubino, E. Vijverberg

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• Special Article

  • ·Aducanumab: Appropriate Use Recommendations Update

    Pagina :221-230

    Jeffrey Cummings, G.D. Rabinovici, A. Atri, P. Aisen, L.G. Apostolova, S. Hendrix, M. Sabbagh, D. Selkoe, M. Weiner, S. Salloway, Alzheimer’s Disease and Related Disorders Therapeutics Working Group

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• Original Research

  • ·Therapeutic Targets for Alzheimer’s Disease: Amyloid Vs. Non-Amyloid. Where Does Consensus Lie Today? An CTAD Task Force Report

    Pagina :231-235

    Serge Gauthier, A. Boxer, D. Knopman, J. Sims, R. Doody, P. Aisen, T. Iwatsubo, R. Bateman, B. Vellas

    Riassunto Riassunto Mappa Mappa

• Point of View

  • ·Digital Therapeutics for MCI and Alzheimer’s disease: A Regulatory Perspective — Highlights From The Clinical Trials on Alzheimer’s Disease conference (CTAD)

    Pagina :236-240

    J. Shuren, P.M. Doraiswamy

    
  • ·Public Policy Should Foster Alzheimer’s Treatment Availability: Comment on the Draft US Medicare Decision to Limit Payment for Aducanumab (Aduhelm™) to Patients Participating in Clinical Trials

    Pagina :241-246

    J. Cummings

    Mappa Mappa  

• Original Research

  • ·A Polymorphism Cluster at the 2q12 locus May Predict Response to Piromelatine in Patients with Mild Alzheimer’s Disease

    Pagina :247-254

    L.S. Schneider, M. Laudon, T. Nir, J. Caceres, G. Ianniciello, M. Capulli, N. Zisapel

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  • ·Sensitivity of the Preclinical Alzheimer’s Cognitive Composite (PACC), PACC5, and Repeatable Battery for Neuropsychological Status (RBANS) to Amyloid Status in Preclinical Alzheimer’s Disease -Atabecestat Phase 2b/3 EARLY Clinical Trial

    Pagina :255-261

    Kathryn V. Papp, H. Rofael, A.E. Veroff, M.C. Donohue, S. Wang, C. Randolph, E. Grober, H. Robert Brashear, G. Novak, K. Ernstrom, R. Raman, P.S. Aisen, R. Sperling, Gary Romano, David Henley

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  • ·Unsupervised Performance of the CogState Brief Battery in the Brain Health Registry: Implications for Detecting Cognitive Decline

    Pagina :262-268

    T. Banh, C. Jin, J. Neuhaus, R.S. Mackin, P. Maruff, N. Stricker, M.W. Weiner, R.L. Nosheny

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  • ·Validity of Online Versus In-Clinic Self-Reported Everyday Cognition Scale

    Pagina :269-276

    Taylor Howell, J. Neuhaus, M.M. Glymour, M.W. Weiner, R.L. Nosheny, Alzheimer’s Disease Neuroimaging Initiative

    Riassunto Riassunto Mappa Mappa  
  • ·Alzheimer’s Disease Prevention Health Coaching

    Pagina :277-285

    Annie Rhodes, J. Inker, J. Richardson, F. Zanjani

    Riassunto Riassunto Mappa Mappa  
  • ·Anxiety and Depressive Symptoms and Cortical Amyloid-β Burden in Cognitively Unimpaired Older Adults

    Pagina :286-296

    Catriona K. Lewis, O.M. Bernstein, J.D. Grill, D.L. Gillen, D.L. Sultzer

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  • ·Dual Task Performance Is Associated with Amyloidosis in Cognitively Healthy Adults

    Pagina :297-305

    Jason K. Longhurst, J.L. Cummings, S.E. John, B. Poston, J.V. Rider, A.M. Salazar, V.R. Mishra, A. Ritter, J.Z. Caldwell, J.B. Miller, J.W. Kinney, M.R. Landers

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  • ·Disease Burden and Attributable Risk Factors of Alzheimer’s Disease and Dementia in China from 1990 to 2019

    Pagina :306-314

    R. Li, J. Qi, Y. Yang, Y. Wu, P. Yin, M. Zhou, Z. Qian, M.H. LeBaige, S.E. McMillin, Haoyan Guo, Hualiang Lin

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  • ·The Association of Heart/Vascular Aging with Mild Cognitive Impairment in a Rural Multiethnic Cohort: The Project FRONTIER Study

    Pagina :315-322

    Duke Appiah, G. Ashworth, A. Boles, N. Nair

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  • ·The Association between Sugar-Sweetened Beverages and Cognitive Function in Middle-Aged and Older People: A Meta-Analysis

    Pagina :323-330

    Q. Sun, Y. Yang, X. Wang, R. Yang, X. Li

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  • ·Plasma MMP-9 Levels as the Future Risk of Conversion to Dementia in ApoE4-Positive MCI Patients: Investigation Based on the Alzheimer’s Disease Neuroimaging Initiative Database

    Pagina :331-337

    K. Abe, Yuhei Chiba, K. Ide, A. Yoshimi, T. Asami, A. Suda, T. Odawara, A. Hishimoto, Alzheimer’s Disease Neuroimaging Initiative

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  • ·Evaluation of Memantine in AAV-AD Rat: A Model of Late-Onset Alzheimer’s Disease Predementia

    Pagina :338-347

    B. Souchet, M. Audrain, S. Alves, R. Fol, S. Tada, N.S. Orefice, B. Potier, P. Dutar, J.-M. Billard, Nathalie Cartier, Jérôme Braudeau

    Riassunto Riassunto Mappa Mappa  

• Review

  • ·The Scottish Brain Health Service Model: Rationale and Scientific Basis for a National Care Pathway of Brain Health Services in Scotland

    Pagina :348-358

    Craig W. Ritchie, J.M.J. Waymont, C. Pennington, K. Draper, A. Borthwick, N. Fullerton, M. Chantler, M.E. Porteous, S.O. Danso, A. Green, L. McWhirter, G. Muniz Terrera, S. Simpson, G. Thompson, D. Trépel, T.J. Quinn, A. Kilgour

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  • ·The Effects of Dual-Task Training on Cognitive and Physical Functions in Older Adults with Cognitive Impairment; A Systematic Review and Meta-Analysis

    Pagina :359-370

    N. Ali, H. Tian, L. Thabane, J. Ma, H. Wu, Q. Zhong, Y. Gao, C. Sun, Yi Zhu, Tong Wang

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• Brief Reports

  • ·Identifying Dementia Risk in Older Veterans Using A Mailing Survey

    Pagina :371-375

    A. Shah, O. Ysea-Hill, A. Torres-Morales, C.J. Gomez, A. Castellanos, Jorge G. Ruiz

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• Study Protocol

  • ·Study Protocol of a Comprehensive Activity Promotion Program for the Prevention of Dementia: A Randomized Controlled Trial Protocol

    Pagina :376-384

    Hiroyuki Shimada, S. Lee, K. Harada, S. Bae, K. Makino, I. Chiba, O. Katayama, H. Arai

    Riassunto Riassunto Mappa Mappa