Sommario

• Editorial

  • ·How Will Aducanumab Approval Impact AD Research?

    Pagina :391-392

    Michael W. Weiner, P.S. Aisen, L.A. Beckett, R.C. Green, W. Jagust, J.C. Morris, O. Okonkwo, R.J. Perrin, R.C. Petersen, M. Rivera Mindt, A.J. Saykin, L.M. Shaw, A.W. Toga, J.Q. Trojanowski, Alzheimer’s Disease Neuroimaging Initiative (ADNI)

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  • ·Consequences of the FDA Decision on Aducanumab for Patient Care and Research

    Pagina :393-395

    Rachelle Doody

    
  • ·Impact of Aduhelm Approval on Care and Policy

    Pagina :396-397

    B. Kallmyer, M. Daven, L. Thornhill, K. Clifford, R. Conant, Maria C. Carrillo

    

• Special Article

  • ·Aducanumab: Appropriate Use Recommendations

    Pagina :398-410

    Jeffrey Cummings, P. Aisen, L.G. Apostolova, A. Atri, S. Salloway, M. Weiner

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• Commentary

  • ·The US Expert Panel on the Appropriate Use Recommendations of Aducanumab in Clinical Practice

    Pagina :411

    Serge Gauthier, P. Rosa-Neto

    

• Editorial

  • ·Aducanumab: Appropriate Use Recommendations

    Pagina :412-413

    Philip Scheltens, E.G.B. Vijverberg

    

• Original Research

  • ·Donanemab (LY3002813) Phase 1b Study in Alzheimer’s Disease: Rapid and Sustained Reduction of Brain Amyloid Measured by Florbetapir F18 Imaging

    Pagina :414-424

    S.L. Lowe, C. Duggan Evans, S. Shcherbinin, Y.-J. Cheng, B.A. Willis, I. Gueorguieva, A.C. Lo, A.S. Fleisher, J.L. Dage, P. Ardayfio, G. Aguiar, M. Ishibai, G. Takaichi, L. Chua, G. Mullins, John R. Sims, AACD Investigators

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  • ·The Cost-Effectiveness of Three Prevention Strategies in Alzheimer’s Disease: Results from the Multidomain Alzheimer Preventive Trial (MAPT)

    Pagina :425-435

    Nadège Costa, M. Mounié, A. Pagès, H. Derumeaux, T. Rapp, S. Guyonnet, N. Coley, C. Cantet, I. Carrié, S. Andrieu, L. Molinier, MAPT/DSA Group

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• Brief Reports

  • ·The Association between Peanut and Peanut Butter Consumption and Cognitive Function among Community-Dwelling Older Adults

    Pagina :436-441

    Elizabeth W. Katzman, S.J. Nielsen

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• Original Research

  • ·Early-Onset Subgroup of Type 2 Diabetes and Risk of Dementia, Alzheimer’s disease and Stroke: A Cohort Study

    Pagina :442-447

    K. Wang, Hong Liu

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  • ·A UK-Wide Study Employing Natural Language Processing to Determine What Matters to People about Brain Health to Improve Drug Development: The Electronic Person-Specific Outcome Measure (ePSOM) Programme

    Pagina :448-456

    Stina Saunders, G. Muniz-Terrera, S. Sheehan, C.W. Ritchie, S. Luz

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  • ·A Fay-Herriot Model for Estimating Subjective Cognitive Decline among Military Veterans

    Pagina :457-461

    Justin T. McDaniel, R.J. McDermott, T. Schneider

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• Editorial

  • ·Alzheimer’s Disease Research in Japan: A Short History, Current Status and Future Perspectives toward Prevention

    Pagina :462-464

    Takeshi Iwatsubo, Y. Niimi, H. Akiyama

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• Original Research

  • ·The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled Trial

    Pagina :465-476

    T. Sugimoto, Takashi Sakurai, H. Akatsu, T. Doi, Y. Fujiwara, A. Hirakawa, F. Kinoshita, M. Kuzuya, S. Lee, K. Matsuo, M. Michikawa, S. Ogawa, R. Otsuka, K. Sato, H. Shimada, H. Suzuki, H. Suzuki, H. Takechi, S. Takeda, H. Umegaki, S. Wakayama, H. Arai, J-MINT investigators

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  • ·Peripheral Blood BRCA1 Methylation Positively Correlates with Major Alzheimer’s Disease Risk Factors

    Pagina :477-482

    Tatsuo Mano, K. Sato, T. Ikeuchi, T. Toda, T. Iwatsubo, A. Iwata, Japanese Alzheimer’s Disease Neuroimaging Initiative

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  • ·Tauroursodeoxycholic Acid Attenuates Diet-Induced and Age-Related Peripheral Endoplasmic Reticulum Stress and Cerebral Amyloid Pathology in a Mouse Model of Alzheimer’s Disease

    Pagina :483-494

    T. Ochiai, T. Nagayama, K. Matsui, K. Amano, T. Sano, Tomoko Wakabayashi, Takeshi Iwatsubo

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  • ·A Japanese Multicenter Study on PET and Other Biomarkers for Subjects with Potential Preclinical and Prodromal Alzheimer’s Disease

    Pagina :495-502

    Michio Senda, K. Ishii, K. Ito, T. Ikeuchi, H. Matsuda, T. Iwatsubo, A. Iwata, R. Ihara, K. Suzuki, K. Kasuga, Y. Ikari, Y. Niimi, H. Arai, A. Tamaoka, Y. Arahata, Y. Itoh, H. Tachibana, Y. Ichimiya, S. Washizuka, T. Odawara, K. Ishii, K. Ono, T. Yokota, A. Nakanishi, E. Matsubara, H. Mori, H. Shimada

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  • ·Cohort-Specific Optimization of Models Predicting Preclinical Alzheimer’s Disease, to Enhance Screening Performance in the Middle of Preclinical Alzheimer’s Disease Clinical Studies

    Pagina :503-512

    K. Sato, T. Mano, R. Ihara, K. Suzuki, Y. Niimi, T. Toda, T. Iwatsubo, Atsushi Iwata, Alzheimer’s disease Neuroimaging Initiative, Japanese Alzheimer’s disease Neuroimaging Initiative, The A4 Study Team

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• CTAD Task Force Paper

  • ·Using Digital Tools to Advance Alzheimer’s Drug Trials During a Pandemic: The EU/US CTAD Task Force

    Pagina :513-519

    Jeffrey Kaye, P. Aisen, R. Amariglio, R. Au, C. Ballard, M. Carrillo, H. Fillit, T. Iwatsubo, G. Jimenez-Maggiora, S. Lovestone, F. Natanegara, K. Papp, M.E. Soto, M. Weiner, B. Vellas, the EU/US CTAD Task Force

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• Original Research

  • ·Comparative Efficacy, Safety, Tolerability, and Effectiveness of Antipsychotics in The Treatment of Dementia-Related Psychosis (DRP): A Systematic Literature Review

    Pagina :520-533

    I. Yunusa, N. Rashid, V. Abler, Krithika Rajagopalan

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• Reviews

  • ·Immunotherapy for Alzheimer’s Disease: Current Scenario and Future Perspectives

    Pagina :534-551

    M.B. Usman, S. Bhardwaj, S. Roychoudhury, D. Kumar, A. Alexiou, P. Kumar, R.K. Ambasta, P. Prasher, S. Shukla, V. Upadhye, F.A. Khan, R. Awasthi, M.D. Shastri, S.K. Singh, G. Gupta, D.K. Chellappan, K. Dua, S.K. Jha, J. Ruokolainen, K.K. Kesari, Shreesh Ojha, Niraj Kumar Jha

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• Letter to the Editor

  • ·Childhood Secondhand Smoke Exposure and Risk of Dementia in Adulthood

    Pagina :552

    Tomoyuki Kawada