P10: Removal of environmental contamination of polybrominated diphenyl ethers (PBDEs) in human hair – Clinical and research implications - 28/06/14
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Riassunto |
Introduction |
Polybrominated diphenyl ether (PBDE) measurement in hair is an important emerging potential biomarker for possible endocrine-disrupting effects in humans. The aim of this study was to evaluate effective removal of environmentally deposited PBDEs while keeping hair intact for measuring incorporated PBDE levels.
Methods |
Non-pooled hair samples from 10 human were subjected to a no wash (control) and three wash treatments: water, SDS solution, and hexane. After the treatments, hair samples (solid phase) and washes (aqueous phase) were analyzed for eight common PBDE congeners using GC/MS using previously established methods.
Results |
The mean total PBDE values for no wash, water wash solid and aqueous phase, SDS solution wash solid and aqueous phases, and hexane wash solid and aqueous phases were: 20.32±9.65, 21.40±10.47, 0.39±0.59, 19.27±5.94, 1.33±2.15, 16.91±9.14 and 1.92±2.76ng/mg respectively (p<0.005). In a comparison of hair PBDE concentrations between unwashed hair and three washing conditions, washing hair with water, SDS solution, and hexane decreased the incorporated levels of PBDEs by 2 %, 7 %, and 33 % respectively (p<0.05).
Conclusion |
Washing hair with water is the most effective method for removing external environmental contamination while keeping the matrix of the hair and PBDE congeners undamaged.
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Vol 26 - N° 2S
P. S34-S35 - Giugno 2014 Ritorno al numero
Articolo precedente
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