Uric acid stones account for 5% to 8% of renal calculi in Western countries.<sup>24 Gutman A.B., Yu T.F. Uric acid nephrolithiasis Am J Med 1968 ;  45 : 756  [cross-ref]

Cliccare qui per andare alla sezione Riferimenti, 67 Yu T.F., Gutman A.B. Uric acid nephrolithiasis in gout. Predisposing factors Ann Intern Med 1967 ;  67 : 1133

Cliccare qui per andare alla sezione Riferimenti</sup> Uric acid–related nephrolithiasis, which includes hyperuricosuric calcium stones, accounts for up to 40% of stones in some series.<sup>47 Pak C.Y.C., Resnick M.I. Introduction Urolithiasis. A Medical and Surgical Reference Philadelphia: WB Saunders (1990).  1

Cliccare qui per andare alla sezione Riferimenti</sup> Unlike most forms of urolithiasis, medical therapy has a pivotal role in active treatment and prophylaxis against stone recurrences. Understanding the pathophysiology and biochemical nature of uric acid leads to a rational treatment approach in patients with uric acid–related urinary stone disease.