Frequency and time course of reocclusion and restenosis in coronary artery occlusions after balloon angioplasty versus wiktor stent implantation: results from the Mayo-Japan Investigation for Chronic Total Occlusion (MAJIC) Trial - 26/08/11
, Peter B Berger, MD b, Etsuo Tsuchikane, MD c, Takahiko Suzuki, MD d, Hideo Nishikawa, MD e, Tadanori Aizawa, MD f, Kenshi Fujii, MD g, Youichi Nozaki, MD h, Eisho Kyo, MD a, Toru Kobayashi, MD c, Johan Reiber, MD i, Anton W.M Van Weert, MD iMAJIC Investigators
Abstract |
Background |
Compared with balloon angioplasty, stent implantation has been shown to reduce restenosis and reocclusion after treatment of chronic total coronary artery occlusions (CTOs). However, little is known about the time course of restenosis and reocclusion after the 2 procedures. The purpose of this study was to examine the frequency and time course of restenosis and reocclusion after treatment of CTOs with balloon angioplasty and Wiktor stent implantation.
Methods and results |
A total of 221 patients with successfully recanalized CTOs were randomly assigned to either treatment with a coil stent implantation (Wiktor stent, n = 110) or standard balloon angioplasty (n = 111). Repeat angiography was performed the day after treatment and at 6 months. Patients undergoing balloon angioplasty showed 29.8% restenosis and 1.1% reocclusion the following day versus 2% restenosis and no reocclusion in stent patients the following day. The cumulative reocclusion rate was significantly lower in the stent group than in the balloon group at 6 months (2.1% versus 9.3%, P < .05). As a result of the more frequent need of target vessel revascularization (49.5% in the balloon group and 30.6% in the stent group, P < .005) and earlier final follow-up angiography in the balloon group, the frequency of angiographic restenosis at 6 months was similar in both groups (57.3% in the stent group and 54.5% in the balloon group).
Conclusions |
The frequency and time course of reocclusion and restenosis after balloon angioplasty and stent placement differ within 24 hours of the procedure and remain different on angiography at 6 months.
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Vol 147 - N° 3
P. 475 - Marzo 2004 Ritorno al numero
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