Patterns and outcomes of drug-eluting coronary stent use in clinical practice - 17/08/11
, Richard E. Shaw, MA, PhD b, Ralph G. Brindis, MD, MPH c, Lloyd W. Klein, MD d, William S. Weintraub, MD e, Ronald J. Krone, MD f, Eric D. Peterson, MD, MPH aRiassunto |
Objective |
To determine patterns and outcomes of drug-eluting stents (DES) use in clinical practice.
Background |
DES are technology associated with superior outcomes. The initial limited availability and high cost of DES had the potential to influence their use.
Methods |
Data from the American College of Cardiology-National Cardiovascular Data Registry were examined to describe the patterns of DES use in 408,033 percutaneous coronary intervention (PCI) procedures at 383 sites. Predictors of DES use were determined, and inhospital outcomes were examined.
Results |
From April 2003 through December 2004, the proportion of procedures using DES increased from 19.7% to 78.2%. DES use increased across all patient groups and hospital types, but adoption was slower among older patients and those without health insurance. DES use varied among hospitals such that use was lower at rural and low-volume hospitals. Multivariable regression demonstrated a progressive decrease in the odds of DES use as age increased. White race, female sex, presence of insurance, diabetes mellitus, PCI of de novo lesion, PCI at a high volume center, and PCI at a suburban hospital were significant predictors of DES use. The availability of a second DES product did not influence the adoption patterns. Inhospital outcomes with DES were excellent.
Conclusions |
Access to DES was influenced by demographic, socioeconomic, and hospital characteristics. Further study is needed to determine if the availability of another DES platform or increased overall availability of DES impacts favorably on PCI practice patterns.
Il testo completo di questo articolo è disponibile in PDF.Mappa
| This analysis was supported by The American College of Cardiology National Cardiovascular Data Registry. |
Vol 152 - N° 2
P. 321-326 - Agosto 2006 Ritorno al numero
Articolo precedente
- Evaluation of AMPD1 C34T genotype as a predictor of mortality in heart failure and post–myocardial infarction patients
- Richard P. Collins, Barry R. Palmer, Anna P. Pilbrow, Chris M. Frampton, Richard W. Troughton, Tim G. Yandle, Lorraine Skelton, A. Mark Richards, Vicky A. Cameron
- Intravascular ultrasound assessment of fibrous cap remnants after coronary plaque rupture
- Lisette Okkels Jensen, Gary S. Mintz, Stéphane G. Carlier, Kenichi Fujii, Issam Moussa, George Dangas, Roxanna Mehran, Gregg W. Stone, Martin B. Leon, Jeffrey W. Moses
Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
L'accesso al testo integrale di questo articolo richiede un abbonamento.
Già abbonato a @@106933@@ rivista ?