Incidence and natural history of coronary artery aneurysm developing after drug-eluting stent implantation - 05/08/11
, Jong-Youn Kim, MD, PhD b, Pil-Ki Min, MD, PhD b, Young W. Yoon, MD, PhD b, Byoung K. Lee, MD, PhD b, Hyuck M. Kwon, MD, PhD b, Jung-Sun Kim, MD, PhD c, Young-Guk Ko, MD, PhD c, Donghoon Choi, MD, PhD c, Myeong-Ki Hong, MD, PhD c, Yangsoo Jang, MD, PhD c, Won-Heum Shim, MD, PhD c, Seung-Yun Cho, MD, PhD c, Byeong-Keuk Kim, MD, PhD d, Seongjin Oh, MD d, Dong W. Jeon, MD d, Joo Y. Yang, MD d, Jae-Hun Jung, MD, PhD eRiassunto |
Aims |
There is a growing concern about the occurrence of coronary artery aneurysms (CAAs) after drug-eluting stent (DES) implantation and their long-term course. We assessed the occurrence and the factors affecting the long-term outcome of DES-associated CAA.
Methods and Results |
We analyzed 3,612 consecutive patients (4,419 lesions) who underwent follow-up angiography after DES implantation. All 34 CAAs (0.76% per lesion) in 29 patients (0.8% per patient) were detected at follow-up, and the mean elapsed time from DES implantation to CAA diagnosis was 414 ± 213 days. Angiographically, CAAs developed almost exclusively in complex (type B2/C) de novo lesions (30 [88.2%] of 34 lesions), and lesion length was significantly greater in patients with CAA than without CAA (26.9 ± 9.03 vs 23.1 ± 7.14 mm; P = .004). Myocardial infarction with stent thrombosis occurred in 5 patients with CAA (17.2%), 4 of whom were on aspirin only without clopidogrel.
Conclusion |
Although CAAs rarely develop after DES implantation and show mostly favorable clinical courses, long-term maintenance of clopidogrel therapy might be required to minimize occurrence of adverse clinical events resulting from stent thrombosis.
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Vol 160 - N° 5
P. 987-994 - Novembre 2010 Ritorno al numero
Articolo precedente
- Differential effects of post-dilation after stent deployment in patients presenting with and without acute myocardial infarction
- Zhi-Jiang Zhang, Oscar C. Marroquin, Roslyn A. Stone, Joel L. Weissfeld, Suresh R. Mulukutla, Faith Selzer, Kevin E. Kip
- Red blood cell storage duration and mortality in patients undergoing percutaneous coronary intervention (Am Heart J 2010;159:876-81)
- Cong Lu, Yu Cheng Chen
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