Amputations as a result of thermal or electrical burns present a unique challenge that requires a coordinated effort by the rehabilitation team. Complications of surface and deep tissue injury require adjustment to the more standard approaches to prosthetic provision. Accommodations for the complications of joint contracture, skin adhesions, sensation compromise, skin grafts, and muscle flaps must be made by the treating clinicians. Differences in the treatment timelines, socket designs, material options, and component choices are discussed to familiarize the team for optimization of function in this difficult treatment scenario.