Sjögren's syndrome with ANCA-associated crescentic extramembranous glomerulonephritis - 10/03/09
, Elisabeth Solau-Gervais a, Alix Coulon b, Françoise Debiais a
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Abstract |
A 49-year-old woman with a 1-year history of Sjögren's syndrome was diagnosed with cutaneous leukocytoclastic vasculitis and necrotizing crescentic membranous glomerulonephritis. Antineutrophil cytoplasmic antibodies targeting myeloperoxidase were found. She reported a transient episode of nephritis 4 years earlier. This pattern of kidney disease is not typical of Sjögren's syndrome. Methylprednisolone boluses followed by oral glucocorticoid therapy were given in combination with mycophenolate mofetil. Renal function stabilized after 2 months, and tests for anti-myeloperoxidase reverted to negative.
Il testo completo di questo articolo è disponibile in PDF.Keywords : Sjögren's syndrome, Leukocytoclastic vasculitis, Antineutrophil cytoplasmic antibodies, Anti-myeloperoxidase antibodies, Necrotizing glomerulonephritis, Mycophenolate mofetil
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Vol 76 - N° 2
P. 188-189 - Marzo 2009 Ritorno al numero
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