Efficacy of a Group-Based 8-Week Multicomponent Cognitive Training on Cognition, Mood and Activities of Daily Living among Healthy Older Adults: A Two-Year Follow-Up of a Randomized Controlled Trial - 05/12/24

Doi : 10.1016/j.tjpad.2024.100033

Patsri Srisuwan ^1,^⁎ , Daochompu Nakawiro ², Orawan Kuha ³, Supatcha Kengpanich ¹, Kulachade Gesakomol ¹, Sirinthorn Chansirikarnjana ⁴
¹ Department of Outpatient and Family Medicine, Phramongkutklao Hospital, Bangkok, Thailand
² Department of Psychiatry, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
³ Institute of Geriatric Medicine, Ministry of Public Health, Nonthaburi, Thailand
⁴ Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

^⁎Correspondence to: Srisuwan P, Department of Outpatient and Family Medicine, Phramongkutklao Hospital, Bangkok, 10400, Thailand. Phone (662) 354-7660 ext. 93100, Fax (662) 354-9006Department of Outpatient and Family MedicinePhramongkutklao HospitalBangkok10400Thailand

connettersi o creare un account

Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
Articolo gratuito.

Si connetta per beneficiarne

In corso di stampa. Manoscritto Accettato. Disponibile online dal Thursday 05 December 2024

Abstract

BACKGROUND

Cognitive training (CT) has been one of the important non-pharmaceutical interventions that could delay cognitive decline. Currently, no definite CT methods are available. Furthermore, little attention has been paid to the effect of CT on mood and instrumental activities of daily living (IADL).

OBJECTIVES

To assess the effectiveness of a multicomponent CT using a training program of executive functions, attention, memory and visuospatial functions (TEAM-V Program) on cognition, mood and instrumental ADL.

DESIGN

A randomized, single-blinded, treatment-as-usual controlled trial.

SETTING

Geriatric clinic in Bangkok, Thailand.

PARTICIPANTS

80 nondemented community-dwelling older adults (mean age 65.7±4.3 years).

INTERVENTION

The CT (TEAM-V) Program or the treatment-as-usual controlled group. The TEAM-V intervention was conducted over 5 sessions, with a 2-week interval between each session. A total of 80 participants were randomized (n=40 the TEAM-V Program; n=40 the control group).

MEASUREMENTS

The Thai version of Montreal Cognitive Assessment (MoCA), The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-cog), Thai version of Hospital Anxiety and Depression Scale (HADS) and The Chula ADL were used to assess at baseline, 6 months, 1 year and 2 years.

RESULTS

Compared with the control arm (n=36), the TEAM-V Program (n=39) was associated with significantly improved general cognition (MoCA, P = 0.02) at 2 years. Compared with baseline, participants receiving the TEAM-V Program were associated with significantly improved immediate recall (word recall task, P < 0.001), retrieval and retention of memory processes (word recognition task, P = 0.01) and attention (number cancellation part A, P = 0.01) at 2 years. No training effects on anxiety (P = 0.94), depression (P = 0.093) and IADL (P = 0.48) were detected.

CONCLUSIONS

The TEAM-V Program was effective in improving global cognitive function. Even though, the program did not significantly improve anxiety, depression and IADL compared with the control group, memory and attention improved in the intervention group compared with baseline. Further studies incorporating a larger sample size, longitudinal follow-up and higher-intensity CT should be conducted.

Il testo completo di questo articolo è disponibile in PDF.

Keywords : activities of daily livings, cognitive decline, cognitive training, mood, older adults