Physical Fitness and Apolipoprotein E Genotype Influence Cortical Networking and Intelligence in Adolescents - 21/11/24
Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
Articolo gratuito.
Si connetta per beneficiarne
Abstract |
AIMS |
This study examined the interactive effect of physical fitness and Apolipoprotein e4 on intelligence and cortical networking in adolescents.
METHODS |
Participants were middle school students consisting of 10 and 8 high- and low-fit e4 carriers (e4+), respectively, and 14 and 10 high- and low-fit non-carriers (e4−), respectively. Inter- and intra-hemispheric coherences were calculated to examine cortico-cortical communication during intelligence test.
RESULTS |
Coherence in low-fit e4+ was lower than in high-fit e4+, while coherence in low-fit e4− was similar to or higher than in high-fit e4−.
CONCLUSION |
The presence of the e4 allele can decrease neural networking 50–60 years before Alzheimer’s disease onset: however, physical fitness may compensate for the negative impact of genotype. Moreover, the beneficial effects of physical fitness may differ depending on functional states of the adolescent brain according to the presence of the e4 allele.
Il testo completo di questo articolo è disponibile in PDF.Key words : Physical fitness, apolipoprotein, Alzheimer’s disease, adolescent, EEG coherence
Mappa
| Conflict of interest: No conflict of interest |
Vol 8 - N° 1
P. 92-99 - Gennaio 2021 Ritorno al numero
Articolo precedente
- A Systematic Review on the Feasibility of Salivary Biomarkers for Alzheimer’s Disease
- M. Bouftas
- The Effect of Baseline Performance and Age on Cognitive Training Improvements in Older Adults: A Qualitative Review
- J.S. Shaw, S.M. Hadi Hosseini
Benvenuto su EM|consulte, il riferimento dei professionisti della salute.