Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting - 02/09/24
Doi : 10.1016/j.jaci.2024.07.022
Benjamin L. Wright, MD a, b, ⁎ 
, Juan Pablo Abonia, MD c, Edsel M. Abud, MD, PhD d, e, Seema S. Aceves, MD, PhD e, Steven J. Ackerman, PhD f, Melinda Braskett, MD g, Joy W. Chang, MD, MS h, Mirna Chehade, MD, MPH i, Gregory M. Constantine, MD j, Carla M. Davis, MD k, Evan S. Dellon, MD, MPH l, Alfred D. Doyle, PhD a, Raquel Durban, RD m, David A. Hill, MD, PhD n, o, Elizabeth T. Jensen, MPH, PhD p, Anupama Kewalramani, MD q, Paneez Khoury, MD, MHSc j, Amy D. Klion, MD j, Leah Kottyan, PhD c, Fei Li Kuang, MD, PhD r, Emily C. McGowan, MD, PhD s, Melanie A. Ruffner, MD, PhD n, o, Lisa A. Spencer, PhD t, Jonathan M. Spergel, MD, PhD n, o, Amiko M. Uchida, MD u, Joshua B. Wechsler, MD, MSc v, Robert D. Pesek, MD w
, Juan Pablo Abonia, MD c, Edsel M. Abud, MD, PhD d, e, Seema S. Aceves, MD, PhD e, Steven J. Ackerman, PhD f, Melinda Braskett, MD g, Joy W. Chang, MD, MS h, Mirna Chehade, MD, MPH i, Gregory M. Constantine, MD j, Carla M. Davis, MD k, Evan S. Dellon, MD, MPH l, Alfred D. Doyle, PhD a, Raquel Durban, RD m, David A. Hill, MD, PhD n, o, Elizabeth T. Jensen, MPH, PhD p, Anupama Kewalramani, MD q, Paneez Khoury, MD, MHSc j, Amy D. Klion, MD j, Leah Kottyan, PhD c, Fei Li Kuang, MD, PhD r, Emily C. McGowan, MD, PhD s, Melanie A. Ruffner, MD, PhD n, o, Lisa A. Spencer, PhD t, Jonathan M. Spergel, MD, PhD n, o, Amiko M. Uchida, MD u, Joshua B. Wechsler, MD, MSc v, Robert D. Pesek, MD w a Department of Medicine, Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Ariz
b Division of Allergy and Immunology, Phoenix Children’s Hospital, Phoenix, Ariz
c Department of Pediatrics, Division of Allergy and Immunology, Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio
d Division of Allergy, Asthma, and Immunology, Scripps Clinic, San Diego, Calif
e Division of Allergy and Immunology, University of California, San Diego, Rady Children’s Hospital, San Diego, Calif
f Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, Ill
g Department of Pediatrics, Division of Clinical Immunology and Allergy, Children’s Hospital Los Angeles, Keck School of Medicine at University of Southern California, Los Angeles, Calif
h Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Mich
i Mount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, New York, NY
j Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md
k Department of Pediatrics, Division of Immunology, Allergy, and Retrovirology, Baylor College of Medicine and Texas Children’s Hospital, Houston, Tex
l Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, NC
m Carolina Asthma and Allergy Center, Charlotte, NC
n Division of Allergy and Immunology, Children’s Hospital of Philadelphia, Philadelphia, Pa
o Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa
p Departments of Epidemiology and Prevention and Internal Medicine, Gastroenterology Section, Wake Forest University School of Medicine, Winston-Salem, NC
q Department of Pediatrics, Division of Pulmonology/Allergy, University of Maryland School of Medicine, Baltimore, Md
r Division of Allergy and Immunology, Northwestern Feinberg School of Medicine, Chicago, Ill
s Departments of Medicine and Pediatrics, Division of Allergy and Clinical Immunology, University of Virginia, Charlottesville, Va
t Department of Pediatrics, Section of Gastroenterology, Hepatology & Nutrition, University of Colorado School of Medicine, Aurora, Colo
u Division of Gastroenterology, Hepatology & Nutrition, University of Utah, Salt Lake City, Utah
v Department of Pediatrics, Division of Gastroenterology, Hepatology & Nutrition, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, Ill
w Division of Allergy and Immunology, Arkansas Children’s Hospital, and the University of Arkansas for Medical Sciences, Little Rock, Ark
∗Corresponding author: Benjamin L. Wright, MD, Mayo Clinic Arizona, 13400 E Shea Blvd, Scottsdale, AZ 85259.Mayo Clinic Arizona13400 E Shea BlvdScottsdaleAZ85259
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Disponibile online dal Monday 02 September 2024
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Abstract |
The Consortium of Eosinophilic Gastrointestinal disease Researchers (CEGIR) and The International Gastrointestinal Eosinophil Researchers (TIGERs) organized a daylong symposium at the 2024 annual meeting of the American Academy of Allergy, Asthma & Immunology. The symposium featured new discoveries in basic and translational research as well as debates on the mechanisms and management of eosinophilic gastrointestinal diseases. Updates on recent clinical trials and consensus guidelines were also presented. We summarize the updates on eosinophilic gastrointestinal diseases presented at the symposium.
Il testo completo di questo articolo è disponibile in PDF.Key words : Eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastrointestinal disease, eosinophil
Abbreviations used : CEGIR, EGID, EoD, EoE, EoG, FDA, FED, PassITON, RT-qPCR, scRNA-Seq, TCR, TIGERs
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