Management of the post amputation wound and skin is an individualized and evolving process. Although no consensus recommendations are available, optimal wound healing occurs with a dressing that provides the appropriate level of moisture, and management of edema, and can assist in contracture prevention and limb protection. Management of comorbid conditions and complications that might impede healing, as well as nutritional optimization help promotes wound closure. A faster time to heal increases the opportunity and likelihood of prosthetic fitting and use, working toward improved functional independence.