Performance of the ESC 0/2h-algorithm using high-sensitivity cardiac troponin I in the early diagnosis of myocardial infarction - 30/10/21
Doi : 10.1016/j.ahj.2021.08.008
Luca Koechlin, MD a, b, c, 1, Jasper Boeddinghaus, MD a, c, 1, Thomas Nestelberger, MD a, c, d, Pedro Lopez-Ayala, MD a, c, Desiree Wussler, MD a, c, e, Samyut Shrestha, MD a, c, e, Tobias Resa, MD a, c, Karin Wildi, MD a, c, f, g, Adam Bakula, MD a, Simon Frey, MD a, Òscar Miró, MD c, h, F Javier Martin-Sanchez, MD c, i, Ivo Strebel, MSc a, c, Danielle M Gualandro, MD a, c, Friedrich S Eckstein, MD b, Oliver Reuthebuch, MD b, Dagmar I Keller, MD j, Raphael Twerenbold, MD a, c, Maria Rubini Giménez, MD a, c, k, Christian Mueller, MD a, c, ⁎ 
for the APACE investigators#
Tobias Zimmermann, MD a, b, Tobias Reichlin, MD a, b, c, Michael Christ, MD a, d, Christian Puelacher, MD, PhD a, b, e, Jeanne du Fay de Lavallaz, MD a, b, Eliska Potlukova, MD, PhD a, b, e, Matthias Diebold, MD a, b, e, Damian Kawecki, MD b, f, Nicolas Geigy, MD g, Katharina Rentsch, PhD h, Sandra Mitrovic, PhD h, Carolina Fuenzalida, MD b, i, Noemi Glarner, MD a, b, f, Beata Morawiec, MD b, g, Piotr Munzk, MD b, g, Tobias Breidthardt, MD a, b, f, Michael Freese, SN a, b, Beatriz López, MD b, i, Sofia Calderón, MD b, i, Esther Rodriguez Adrada, MD b, j, Eva Ganovská, MD b, k, Jiri Parenica, MD b, k, Arnold von Eckardstein, MD l, Isabel Campodarve, MD m, Joaquim Gea, MD m
a Cardiovascular Research Institute Basel (CRIB) and Department of Cardiology, University Hospital Basel, University of Basel, Switzerland
b GREAT network
c Department of Cardiology, Inselspital, University of Bern, Rome, Italy
d Emergency Department, Kantonsspital Luzern, Switzerland
e Department of Internal Medicine, University Hospital Basel, University of Basel, Switzerland
f 2nd Department of Cardiology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Katowice, Poland
g Critical Care Research Group, and The University of Queensland, Brisbane, Australia
h Laboratory Medicine, University Hospital Basel, Switzerland
i Servicio de Urgencias, Hospital Clínico San Carlos, Madrid, Spain
j Hospital Clínico San Carlos, Madrid, Spain
k Department of Cardiology, University Hospital Brno, Brno, Czech Republic and Medical Faculty, Masaryk University, Brno, Czech Republic
l Department of Laboratory Medicine, University Hospital Zurich, Zurich, Switzerland
m Hospital del Mar - IMIM. UPF. CIBERES. Barcelona, Spain
a Cardiovascular Research Institute Basel (CRIB) and Department of Cardiology, University Hospital Basel, University of Basel, Basel, Switzerland
b Department of Cardiac Surgery, University Hospital Basel, University of Basel, Basel, Switzerland
c GREAT network
d Division of Cardiology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada
e Division of Internal Medicine, University Hospital Basel, University of Basel, Basel, Switzerland
f Critical Care Research Group, the Prince Charles Hospital, Brisbane, Australia
g University of Queensland, Brisbane, Australia
h Emergency Department, Hospital Clinic, Barcelona, Catalonia, Spain
i Hospital Clínico San Carlos, Madrid, Spain
j Emergency Department, University Hospital Zurich, Zurich, Switzerland
k Department of Internal Medicine/Cardiology, Heart Center Leipzig at University of Leipzig, Germany
⁎Reprint requests: Christian Mueller, MD, CRIB and Department of Cardiology, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland.CRIB and Department of CardiologyUniversity Hospital BaselPetersgraben 4BaselCH-4031Switzerland
Riassunto |
The 2020 guidelines of the European Society of Cardiology (ESC) recommend a novel ESC 0/2h-algorithm as the preferred alternative to the ESC 0/1h-algorithm in the early triage for rule-out and/or rule-in of Non-ST-segment-elevation myocardial infarction (NSTEMI). The aim was to prospectively validate the performance of the ESC 0/2h-algorithm using the high-sensitivity cardiac troponin I (hs-cTnI) assay (ARCHITECT) in an international, multicenter diagnostic study enrolling patients presenting with acute chest discomfort to the emergency department.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations : CI, CPO, ED, ESC, hs-cTnI, IQR, NPV, NSTEMI, PPV, STEMI
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© 2021
Elsevier Inc. Tutti i diritti riservati.
Vol 242
P. 132-137 - dicembre 2021 Ritorno al numero
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