The role of miRNA125b in the progression of hepatocellular carcinoma - 28/10/21
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Abstract |
Hepatocellular carcinoma (HCC) is one of the most common tumours worldwide, and identifying markers related to HCC is an important area of research. As a microRNA (miRNA), miRNA125b (miR-125b) plays an important role in the prediction and prognosis of HCC. In the past 10 years, with increasing research on miR-125b and HCC, the molecular mechanism of its relationship with the development of HCC has been elucidated. MiR-125b inhibits the development of HCC and is highly accurate in predicting HCC and is therefore a valuable predictive marker of HCC. This article summarizes the clinical application of miR-125b in HCC and the potential mechanism of its involvement in the progression of HCC.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations : HCC, miRNAs, miR-125b, SR, LT, KM, HR, OS, DFS, ROC, AUC, HBV, AFP, 5-FU, HK-2, EVA1A, EZH2, IGF1R, GLPS, Notch1, ASG, TACE, HIF-1α, IL6R, CDK1, CCNA2, STAT3, SIRT7, IGF2, TAZ, VETC, Angpt2, EMT, TGF-β1, ERManI, SMAD, PIGF, lncRNAs, HOTTIP, SIRT6, TXNRD1, SUV39H, LIN28B, circRNAs, TAM
Keywords : miRNA125b, Hepatocellular carcinoma, Progression
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Vol 45 - N° 5
Articolo 101712- Settembre 2021 Ritorno al numero
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