Endovascular treatment for native coarctation in children in France. A multicentric, retrospective long-term analysis - 14/08/21
Riassunto |
Background |
Percutaneous treatment of native coarctation (coA), gold standard in adult patients, is still debated in children. We aim to report the French multicentre experience.
Methods |
All patients aged 1 to 18 yrs with native coA, treated percutaneously between 01/2000 and 12/2018, were included in this multcentric (9 centres) retrospective survey.
Results |
One hundred and thirty three children (34 female) were included. Indication for treatment was hypertension in 109, exercise hypertension in 8 and other reasons in 16 patients. Mean age at intervention was 11.5±3.9 years, mean weight 41±18kg. Procedure consisted of isolated balloon dilatation in 5 (mean age 2,63 yrs, mean weight 12kg), balloon dilatation followed by stent implantation in 8 (mean age 11 yrs, mean weight 37kg), and immediate stent implantation in 120 (mean age 12 yrs, mean weight 43kg). Stents used (n=124/128) were covered in 43, non-covered in 77, including 38 open cell stents. Invasive gradient across coA dropped from 28mmHg (range 5 to 64) at baseline (n=124) to 3mmHg (range -5 to 20) after intervention (n= 105). Three associated lesions were treated: 1 PDA closure, 1 aortic valvuloplasty and 1 left SVC occlusion. Serious vascular complications occurred in 8 patients (6%) (3 pseudo-aneurysms, 2 dissections, 2 stenosis and 1 occlusion) requiring surgery in 2. Reintervention was performed in 22%: 2 patients had surgery, 28 were treated percutaneously (14 balloon dilatations, 14 stent implantations). Mean follow-up reached 4.9±4.7 years. At latest follow-up, 25% remained hypertensive with 15 patients (11%) on anti-hypertensive medication. MRI, CTscan or fluoroscopy imaging, are available in 52 patients during follow-up (39%). Rate of aneurysm formation, stent fracture and risks factors for reintervention or residual hypertension will be presented.
Conclusions |
Percutaneous treatment of native coarctation was safe and efficient in our french population. Close follow-up is required for longer-term results.
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Vol 13 - N° 4
P. 280-281 - Settembre 2021 Ritorno al numeroBenvenuto su EM|consulte, il riferimento dei professionisti della salute.