Cardiovascular complications in COVID-19 - 18/04/20

Doi : 10.1016/j.ajem.2020.04.048

Brit Long, MD ^a,^{^⁎} , William J. Brady, MD ^b , Alex Koyfman, MD ^c, Michael Gottlieb, MD ^d
^a Brooke Army Medical Center, Department of Emergency Medicine, 3841 Roger Brooke Dr, Fort Sam Houston, TX 78234, United States
^b Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, VA 22903, United States
^c The University of Texas Southwestern Medical Center, Department of Emergency Medicine, 5323 Harry Hines Boulevard, Dallas, TX 75390, United States
^d Department of Emergency Medicine, Rush University Medical Center, Chicago, IL 60612, United States

^⁎Corresponding author at: 3841 Roger Brooke Dr, Fort Sam Houston, TX 78234, United States.3841 Roger Brooke DrFort Sam HoustonTX78234United States

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In corso di stampa. Prove corrette dall'autore. Disponibile online dal Saturday 18 April 2020

Abstract

Background

The coronavirus disease of 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While systemic inflammation and pulmonary complications can result in significant morbidity and mortality, cardiovascular complications may also occur.

Objective

This brief report evaluates cardiovascular complications in the setting of COVID-19 infection.

Discussion

The current COVID-19 pandemic has resulted in over one million infected worldwide and thousands of death. The virus binds and enters through angiotensin-converting enzyme 2 (ACE2). COVID-19 can result in systemic inflammation, multiorgan dysfunction, and critical illness. The cardiovascular system is also affected, with complications including myocardial injury, myocarditis, acute myocardial infarction, heart failure, dysrhythmias, and venous thromboembolic events. Current therapies for COVID-19 may interact with cardiovascular medications.