Cardiovascular risk factors in patients with spondyloarthritis from Northern European and Mediterranean countries: An ancillary study of the ASAS-COMOSPA project - 20/06/18

Doi : 10.1016/j.jbspin.2017.07.006

Clementina López-Medina ^a,^b,^c,^⁎,^{^{1
These authors contributed equally to this work.}} , Yolanda Jiménez-Gómez ^a,^b,^c,^{^{1
These authors contributed equally to this work.}}, Anna Moltó ^d,^e, Ruxandra Elena Schiotis ^f, Helena Marzo-Ortega ^g, Floris A. van Gaalen ^h, Salih Ozgocmen ⁱ, Maxime Dougados ^d,^e, Jerusalem Calvo-Gutiérrez ^a,^b,^c, M. Carmen Castro-Villegas ^a,^b,^c, Eduardo Collantes-Estévez ^a,^b,^c, Pilar Font-Ugalde ^a,^b,^c
on behalf of the
ASAS-COMOSPA task force^²
See section “Acknowledgements”.
^a Maimónides Institute for Research in Biomedicine of Cordoba (IMIBIC), 14004 Córdoba, Spain
^b Rheumatology Department, Reina Sofia University Hospital, Avda. Menendez Pidal, s/n., 14004 Córdoba, Spain
^c Córdoba University (UCO), 14004 Córdoba, Spain
^d Paris Descartes University, Rheumatology Department, Cochin Hospital, AP–HP, 75014 Paris, France
^e Inserm (U1153), Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, 75014 Paris, France
^f Iuliu Hatieganu, University of Medicine and Pharmacy and Department of Rheumatology, SCBI, 400012 Cluj-Napoca, Romania
^g Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Alberton Hospital, LS7 4SA Leeds, UK
^h Leiden University Medical Center, 2333 ZA Leiden, The Netherlands
ⁱ Department of Rheumatology, Medicalpark Gaziosmanpasa, 34250 Istambul, Turkey

^⁎Corresponding author. Reina Sofia University Hospital, IMIBIC, Córdoba University, Avda. Menendez Pidal, s/n. 14004 Córdoba, Spain.Reina Sofia University Hospital, IMIBIC, Córdoba University, Avda. Menendez Pidal, s/n. 14004 Córdoba, Spain.

Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
L'accesso al testo integrale di questo articolo richiede un abbonamento.

Abbonarsi

pagine	7
Iconografia	2
Video	0
Altro	0

Abstract

Objectives

The objectives of this study were: (1) to compare the prevalence of cardiovascular disease and cardiovascular risk factors among different phenotypes of spondyloarthritis (SpA); (2) to assess the differences in cardiovascular disease and cardiovascular risk factors between two geographical areas, i.e. Northern Europe vs. Mediterranean region; (3) to identify potential predictive factors for high Framingham Risk Score regarding disease features in SpA and geographical area.

Methods

Ancillary analysis of the international, multicentric, observational, cross-sectional ASAS-COMOSPA study. Cardiovascular disease and cardiovascular risk factors were compared depending on SpA phenotype and geographical regions. Potential factors associated with higher cardiovascular risk (i.e. Framingham Risk Score) were determined by a multiple logistic regression.

Results

The most frequent cardiovascular risk factor and cardiovascular disease were smoking (31.2%) and ischemic heart disease (3.2%), respectively. Regarding SpA phenotype, axial SpA patients showed significantly lower prevalence (P<0.05) of hypertension (19.2% vs. 33.8% vs. 26.6% for axial, peripheral and mixed phenotypes, respectively), type 2 diabetes mellitus (4.3% vs. 8.5% vs. 7.4%), dyslipidemia (13.9% vs. 28.4% vs. 15.2%) and ischemic heart disease (2.4% vs. 7.0% vs. 3.2%). Regarding geographical area, a higher frequency of hypertension (34.7% vs. 19.4%,), dyslipidemia (19.3% vs. 14.4%), obesity (29.3% vs. 20.7%) and ischemic heart disease (6.2% vs. 1.8%) was observed for Northern Europe vs. Mediterranean Region, respectively.

Conclusions

Our results suggest that SpA phenotype and geographical area are associated with the prevalence of cardiovascular risk factors and the cardiovascular risk itself, observed in patients in the ASAS-COMOSPA cohort.

Il testo completo di questo articolo è disponibile in PDF.

Keywords : Spondyloarthritis, Cardiovascular disease, Cardiovascular risk factors, Sociodemographic characteristics

Mappa

Introduction

Methods

Study design

Participants and recruitment

Disclosure of interest

Esportazione

Vol 85 - N° 4

P. 447-453 - luglio 2018 Ritorno al numero

Articolo precedente

Anti -citrullinated peptide antibodies profiling in established rheumatoid arthritis
Maria Laura Manca, Alessia Alunno, Claudia D’Amato, Onelia Bistoni, Ilaria Puxeddu, Roberto Gerli, Paola Migliorini, Federico Pratesi

| Articolo seguente

Incidence of cancer in patients with spondyloarthritis treated with anti-TNF drugs
Fabiola Atzeni, Antonio Carletto, Rosario Foti, Marco Sebastiani, Valentina Panetta, Fausto Salaffi, Gianluca Bonitta, Florenzo Iannone, Elisa Gremese, Marcello Govoni, Antonio Marchesoni, Ennio Giulio Favalli, Roberto Gorla, Roberta Ramonda, Piercarlo Sarzi-Puttini, Gianfranco Ferraccioli, Giovanni Lapadula, GISEA group

Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
L'accesso al testo integrale di questo articolo richiede un abbonamento.

Abbonarsi

Già abbonato a @@106933@@ rivista ?

connettersi o creare un account

Cardiovascular risk factors in patients with spondyloarthritis from Northern European and Mediterranean countries: An ancillary study of the ASAS-COMOSPA project - 20/06/18

Abstract

Objectives

Methods

Results

Conclusions

Mappa

Citazioni Export

File

Contenuto

Il mio account

Aide & support

Dichiarazione CNIL