Índice

• • ·Cover 1

    Página :OFC

    
• • ·Brief Overview of This Month's JACI

    Página :A5

    
• • ·Table of Contents

    Página :A7

    
• • ·Editorial Board

    Página :A30

    

• Reader services

  • ·Information for Readers

    Página :A31

    
  • ·News & Notes

    Página :A32

    Esquema Esquema  
  • ·CME Calendar-AAAAI

    Página :A35

    

• Reviews and feature articles

  • ·Biologics in the treatment of asthma in children and adolescents

    Página :581-589

    Leonard B. Bacharier, Daniel J. Jackson

    Resumen Resumen Esquema Esquema  
  • ·Might biologics serve to interrupt the atopic march?

    Página :590-594

    Jonathan M. Spergel, George Du Toit, Carla M. Davis

    Resumen Resumen Esquema Esquema  
  • ·The role of biologics in pediatric food allergy and eosinophilic gastrointestinal disorders

    Página :595-606

    Sayantani B. Sindher, Suzanne Barshow, Jyothi Tirumalasetty, Stefania Arasi, Dan Atkins, Maureen Bauer, Philippe Bégin, Margaret H. Collins, Antoine Deschildre, Alfred D. Doyle, Alessandro Fiocchi, Glenn T. Furuta, Maria Garcia-Lloret, Maurizio Mennini, Marc E. Rothenberg, Jonathan M. Spergel, Julie Wang, Robert A. Wood, Benjamin L. Wright, Torsten Zuberbier, Andrew R. Chin, Andrew Long, Kari C. Nadeau, R. Sharon Chinthrajah

    Resumen Resumen Esquema Esquema  
  • ·Biologics and JAK inhibitors for the treatment of monogenic systemic autoinflammatory diseases in children

    Página :607-618

    Yan Du, Meng Liu, Peter A. Nigrovic, Fatma Dedeoglu, Pui Y. Lee

    Resumen Resumen Esquema Esquema   
  • ·25 Years of translational research in the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC)

    Página :619-633

    Hans Bisgaard, Bo Chawes, Jakob Stokholm, Marianne Mikkelsen, Ann-Marie Malby Schoos, Klaus Bønnelykke

    Resumen Resumen Esquema Esquema   
  • ·Neutrophils in host defense, healing, and hypersensitivity: Dynamic cells within a dynamic host

    Página :634-655

    Marie Siwicki, Paul Kubes

    Resumen Resumen Esquema Esquema  
  • ·Environmental justice and allergic disease: A Work Group Report of the AAAAI Environmental Exposure and Respiratory Health Committee and the Diversity, Equity and Inclusion Committee

    Página :656-670

    Allison J. Burbank, Michelle L. Hernandez, Akilah Jefferson, Tamara T. Perry, Wanda Phipatanakul, Jill Poole, Elizabeth C. Matsui

    Resumen Resumen Esquema Esquema  
  • ·In lasting tribute: Dr Hans Bisgaard, January 24, 1955, to September 8, 2022

    Página :671-672

    Klaus Bønnelykke, Bo Chawes, Jakob Stokholm, Nilofar V. Følsgaard, Ann-Marie M. Schoos, Marianne Mikkelsen

     

• The Editors' choice

  • ·The Editors’ Choice

    Página :673-678

    Esquema Esquema  

• News beyond our pages

  • ·News beyond our pages

    Página :679-680

    Marc E. Rothenberg, Jean Bousquet

    Esquema Esquema  

• Paradigms and perspectives

  • ·Biologics in the management of childhood atopic dermatitis

    Página :681-685

    Sneha Butala, Amy S. Paller

    Esquema Esquema  
  • ·Immunodeficiency secondary to biologics

    Página :686-690

    Roxane Labrosse, Elie Haddad

    Esquema Esquema  
  • ·Knowledge gaps and future opportunities for biologics in childhood allergic and immunologic disorders

    Página :691-693

    Cullen M. Dutmer, Andrew H. Liu

    Esquema Esquema  

• Editorials

  • ·In search of the Holy Grail in atopic dermatitis: Will dupilumab become the first disease-modifying atopic dermatitis drug?

    Página :694-696

    Thomas Bieber

     
  • ·Patients with CVID have their own “gut feeling” for viruses

    Página :697-699

    Raffaele De Palma

     

• Asthma and lower airway disease

  • ·Eosinophil depletion with benralizumab is associated with attenuated mannitol airway hyperresponsiveness in severe uncontrolled eosinophilic asthma

    Página :700

    Rory Chan, Chris RuiWen Kuo, Sunny Jabbal, Brian J. Lipworth

    Resumen Resumen Esquema Esquema  
  • ·The upper-airway microbiome as a biomarker of asthma exacerbations despite inhaled corticosteroid treatment

    Página :706-715

    Javier Perez-Garcia, Mario González-Carracedo, Antonio Espuela-Ortiz, José M. Hernández-Pérez, Ruperto González-Pérez, Olaia Sardón-Prado, Elena Martin-Gonzalez, Elena Mederos-Luis, Paloma Poza-Guedes, Paula Corcuera-Elosegui, Ariel Callero, Inmaculada Sánchez-Machín, Javier Korta-Murua, José A. Pérez-Pérez, Jesús Villar, Maria Pino-Yanes, Fabian Lorenzo-Diaz

    Resumen Resumen Esquema Esquema   
  • ·Indoor environmental exposures and obstructive lung disease phenotypes among children with asthma living in poor urban neighborhoods

    Página :716

    Torie Grant, Travis Lilley, Meredith C. McCormack, Paul J. Rathouz, Roger Peng, Corinne A. Keet, Ana Rule, Meghan Davis, Susan Balcer-Whaley, Michelle Newman, Elizabeth C. Matsui

    Resumen Resumen Esquema Esquema  

• Rhinitis, sinusitis, and ocular allergy

  • ·Chronic rhinosinusitis patients display an aberrant immune cell localization with enhanced S aureus biofilm metabolic activity and biomass

    Página :723

    Gohar Shaghayegh, Clare Cooksley, George Spyro Bouras, Beula Subashini Panchatcharam, Rejhan Idrizi, Metta Jana, Sarah Ellis, Alkis James Psaltis, Peter-John Wormald, Sarah Vreugde

    Resumen Resumen Esquema Esquema  

• Atopic dermatitis and inflammatory skin disease

  • ·IL-31–generating network in atopic dermatitis comprising macrophages, basophils, thymic stromal lymphopoietin, and periostin

    Página :737

    Takashi Hashimoto, Hiroo Yokozeki, Hajime Karasuyama, Takahiro Satoh

    Resumen Resumen Esquema Esquema  

• Biologics and immunotherapy

  • ·Comparative efficacy of tezepelumab to mepolizumab, benralizumab, and dupilumab in eosinophilic asthma: A Bayesian network meta-analysis

    Página :747-755

    Tanawin Nopsopon, Grace Lassiter, Ming-Li Chen, G. Caleb Alexander, Corinne Keet, Hwanhee Hong, Ayobami Akenroye

    Resumen Resumen Esquema Esquema   
  • ·Attenuating the atopic march: Meta-analysis of the dupilumab atopic dermatitis database for incident allergic events

    Página :756-766

    Gregory P. Geba, Dateng Li, Meng Xu, Kusha Mohammadi, Richa Attre, Marius Ardeleanu, Bret Musser

    Resumen Resumen Esquema Esquema   

• Translational and clinical immunology

  • ·Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses

    Página :767-777

    Mari Kaarbø, Mingyi Yang, Johannes R. Hov, Kristian Holm, Mirta Mittelstedt Leal de Sousa, Magnhild E. Macpherson, Henrik M. Reims, Anne-Marte Bakken Kran, Bente Halvorsen, Tom H. Karlsen, Pål Aukrust, Knut E.A. Lundin, Børre Fevang, Magnar Bjørås, Silje Fjellgård Jørgensen

    Resumen Resumen Esquema Esquema   

• Brief reports

  • ·Do upper respiratory viruses contribute to racial and ethnic disparities in emergency department visits for asthma?

    Página :778

    Darlene Bhavnani, Matthew Wilkinson, Rebecca A. Zárate, Susan Balcer-Whaley, Daniel S.W. Katz, Paul J. Rathouz, Elizabeth C. Matsui

    Resumen Resumen Esquema Esquema  
  • ·Biallelic TLR4 deficiency in humans

    Página :783

    Melania Capitani, Ahmad A. Al-Shaibi, Sumeet Pandey, Lisa Gartner, Henry Taylor, Satanay Z. Hubrack, Nourhen Agrebi, Muneera Jassim Al-Mohannadi, Saad Al Kaabi, Thomas Vogl, Johannes Roth, Daniel Kotlarz, Christoph Klein, Adrian K. Charles, Vinayan Vijayakumar, Mohammed Yousuf Karim, Bruce George, Simon P. Travis, Mamoun Elawad, Bernice Lo, Holm H. Uhlig

    Resumen Resumen Esquema Esquema  
  • ·Human MD2 deficiency—an inborn error of immunity with pleiotropic features

    Página :791

    Yue Li, Ziqi Yu, Madlin Schenk, Irena Lagovsky, David Illig, Christoph Walz, Meino Rohlfs, Raffaele Conca, Aleixo M. Muise, Scott B. Snapper, Holm H. Uhlig, Ben Zion Garty, Christoph Klein, Daniel Kotlarz

    Resumen Resumen Esquema Esquema  
  • ·Untargeted serum metabolomic analysis reveals a role for purinergic signaling in FPIES

    Página :797-802

    Daniel Lozano-Ojalvo, Xin Chen, David Dunkin, Charuta Agashe, Mary Grace Baker, J. Andrew Bird, Elena Molina, Anna Nowak-Wegrzyn, M. Cecilia Berin

    Resumen Resumen Esquema Esquema   

• Correspondence

  • ·Accurate phenotyping of cross-reactive hypersensitivity is essential to shed light on the underlying mechanisms in NSAID-induced urticaria/angioedema

    Página :803

    José Antonio Cornejo-García, Rafael Núñez, María J. Torres, Inmaculada Doña

    
  • ·Reply

    Página :803-804

    Sen Hee Tay, Amelia Santosa, Bernett Teck Kwong Lee, Paul Lorenz Bigliardi

    
  • ·HαT is associated with increased risk for severe Hymenoptera venom–triggered anaphylaxis

    Página :804-805

    Julij Šelb, Matija Rijavec, Peter Kopač, Jonathan J. Lyons, Peter Korošec

    
  • ·Reply

    Página :806

    Joshua A. Boyce

    

• Corrigenda

  • ·Corrigenda

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  • ·Corrigendum

    Página :807