Índice

• • ·Cover 1

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• • ·Brief Overview of This Month's JACI

    Página :A5

    
• • ·Table of Contents

    Página :A7

    
• • ·Editorial Board

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• Reader services

  • ·Information for Readers

    Página :A32

    
  • ·News & Notes

    Página :A41

    Esquema Esquema  
  • ·CME Calendar-AAAAI

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• Reviews and feature articles

  • ·Recent trends in food protein–induced enterocolitis syndrome (FPIES)

    Página :43-46

    Mary Grace Baker, Hugh A. Sampson

    Resumen Resumen Esquema Esquema  
  • ·Sterols and immune mechanisms in asthma

    Página :47-59

    Rodney D. Britt, Ned Porter, Mitchell H. Grayson, Kymberly M. Gowdy, Megan Ballinger, Kara Wada, Hye-Young Kim, Mireia Guerau-de-Arellano

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  • ·Recent progress in the genetic and epigenetic underpinnings of atopy

    Página :60-69

    Carolyn H. Baloh, Rasika A. Mathias

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  • ·Immune dysregulation

    Página :70-80

    Andrew Long, Anatole Kleiner, R. John Looney

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  • ·Treatment for food allergy: Current status and unmet needs

    Página :1-14

    Jennifer A. Dantzer, Edwin H. Kim, R. Sharon Chinthrajah, Robert A. Wood

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  • ·T-cell epitope discovery and single-cell technologies to advance food allergy research

    Página :15-20

    Sloan A. Lewis, Bjoern Peters

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  • ·Mast cells in food allergy: Inducing immediate reactions and shaping long-term immunity

    Página :21-25

    Hans C. Oettgen

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  • ·Endotypes of atopic dermatitis and food allergy

    Página :26-28

    Jessica W. Hui-Beckman, Elena Goleva, Evgeny Berdyshev, Donald Y.M. Leung

    Resumen Resumen
  • ·Psychosocial functioning in pediatric food allergies: A scoping review

    Página :29-36

    Grace K. Cushman, Kristine Durkin, Rebecca Noga, Frances Cooke, Linda Herbert, Cynthia Esteban, Elizabeth L. McQuaid

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  • ·Social disparities in early childhood prevention and management of food allergy

    Página :37-41

    Roxanne Dupuis, Wanda Phipatanakul, Lisa M. Bartnikas

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  • ·Social disparities in early childhood prevention and management of food allergy

    Página :42

    

• Fundamentals of allergy and immunology

  • ·From thymus to tissues and tumors: A review of T-cell biology

    Página :81-97

    Laura Chopp, Christopher Redmond, John J. O’Shea, Daniella M. Schwartz

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• The Editors' choice

  • ·The Editors’ Choice

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    Esquema Esquema  

• News beyond our pages

  • ·News beyond our pages

    Página :104-105

    Marc E. Rothenberg, Jean Bousquet

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• Editorials

  • ·Double-barrel targeting of IFN-γ to treat hemophagocytic lymphohistiocytosis

    Página :106-107

    Randy Q. Cron

     
  • ·Sphingolipids in viral skin superinfection: Friend or foe?

    Página :108-109

    Sumanth Chennareddy, Patrick M. Brunner

     

• COVID-19

  • ·Comorbidity defines asthmatic patients' risk of COVID-19 hospitalization: A global perspective

    Página :110-117

    Chrysanthi Skevaki, R. Sharon Chinthrajah, Daria Fomina, Gernot Rohde, Shu Cao, Ziyuan He, Sofia Serdotetskova, Christian Seidemann, Achim Grünewaldt, Abisha Vengadeswaran, Min Xie, Antonina Karsonova, Alexander Karaulov, Kari C. Nadeau, Ho-Ryun Chung, Harald Renz

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• Asthma and lower airway disease

  • ·Exacerbation-prone pediatric asthma is associated with arginine, lysine, and methionine pathway alterations

    Página :118

    Kirsten A. Cottrill, Susan T. Stephenson, Ahmad F. Mohammad, Susan O. Kim, Nael A. McCarty, Rishikesan Kamaleswaran, Anne M. Fitzpatrick, Joshua D. Chandler

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  • ·Multidimensional endotyping using nasal proteomics predicts molecular phenotypes in the asthmatic airways

    Página :128-137

    Ioana Agache, Mohamed H. Shamji, Nazanin Zounemat Kermani, Giulia Vecchi, Alberto Favaro, Janice A. Layhadi, Anja Heider, Didem Sanver Akbas, Paulina Filipaviciute, Lily Y.D. Wu, Catalina Cojanu, Alexandru Laculiceanu, Cezmi A. Akdis, Ian M. Adcock

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  • ·Determinants of lung function across childhood in the Severe Asthma Research Program (SARP) 3

    Página :138

    Jonathan M. Gaffin, Carter R. Petty, Ronald L. Sorkness, Loren C. Denlinger, Brenda R. Phillips, Ngoc P. Ly, Benjamin Gaston, Kristie Ross, Anne Fitzpatrick, Leonard B. Bacharier, Mark D. DeBoer, W. Gerald Teague, Sally E. Wenzel, Sima Ramratnam, Elliot Israel, David T. Mauger, Wanda Phipatanakul, National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators

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• Atopic dermatitis and inflammatory skin disease

  • ·Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms

    Página :147-158

    Juan José Yepes-Nuñez, Gordon H. Guyatt, Luis Guillermo Gómez-Escobar, Lucia C. Pérez-Herrera, Alexandro W.L. Chu, Renata Ceccaci, Ana Sofía Acosta-Madiedo, Aaron Wen, Sergio Moreno-López, Margaret MacDonald, Mónica Barrios, Xiajing Chu, Nazmul Islam, Ya Gao, Melanie M. Wong, Rachel Couban, Elizabeth Garcia, Edgardo Chapman, Paul Oykhman, Lina Chen, Tonya Winders, Rachel Netahe Asiniwasis, Mark Boguniewicz, Anna De Benedetto, Kathy Ellison, Winfred T. Frazier, Matthew Greenhawt, Joey Huynh, Elaine Kim, Jennifer LeBovidge, Mary Laura Lind, Peter Lio, Stephen A. Martin, Monica O’Brien, Peck Y. Ong, Jonathan I. Silverberg, Jonathan Spergel, Julie Wang, Kathryn E. Wheeler, Lynda Schneider, Derek K. Chu

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  • ·Infiltration and local differentiation of bone marrow–derived integrinβ7-positive mast cell progenitors in atopic dermatitis–like skin

    Página :159

    Yuki Honda Keith, Tetsuya Honda, Sachiko Ono, Bernett Lee, Rintaro Shibuya, Sho Hanakawa, Yoshihiro Ishida, Satoshi Nakamizo, Kenji Kabashima

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  • ·Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies

    Página :172-181

    Emma Guttman-Yassky, Jacob P. Thyssen, Jonathan I. Silverberg, Kim A. Papp, Amy S. Paller, Stephan Weidinger, H. Chih-ho Hong, Barbara Hendrickson, Deanne Dilley, Allan R. Tenorio, Barry Ladizinski, Alvina D. Chu, John Liu, Alan D. Irvine

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• Food allergy and gastrointestinal disease

  • ·IL-4 receptor alpha signaling alters oral food challenge and immunotherapy outcomes in mice

    Página :182

    Varsha Ganesan, Ankit Sharma, Sunil Tomar, Charles F. Schuler, Simon P. Hogan

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• Biologics and immunotherapy

  • ·Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: A randomized controlled trial

    Página :192-201

    Jonathan Corren, David Larson, Matthew C. Altman, R. Max Segnitz, Pedro C. Avila, Paul A. Greenberger, Fuad Baroody, Mark H. Moss, Harold Nelson, Allison J. Burbank, Michelle L. Hernandez, David Peden, Sarbjit Saini, Stephen Tilles, Iftikhar Hussain, Don Whitehouse, Tielin Qin, Miguel Villarreal, Michelle Sever, Lisa M. Wheatley, Gerald T. Nepom, Srinath Sanda, Immune Tolerance Network ITN057AD CATNIP Study Team

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• Mechanisms of allergy/immunology

  • ·Expression and regulation of Siglec-6 (CD327) on human mast cells and basophils

    Página :202-211

    Dubravka Smiljkovic, Harald Herrmann, Irina Sadovnik, Susanne Gamperl, Daniela Berger, Gabriele Stefanzl, Gregor Eisenwort, Gregor Hoermann, Sonja Kopanja, Yulia Dorofeeva, Margarete Focke-Tejkl, Peter Jaksch, Konrad Hoetzenecker, Zsolt Szepfalusi, Rudolf Valenta, Michel Arock, Peter Valent

    Resumen Resumen Esquema Esquema   
  • ·Prenatal exposure to ambient air pollution is associated with early life immune perturbations

    Página :212-221

    Casper-Emil Tingskov Pedersen, Anders Ulrik Eliasen, Matthias Ketzel, Jørgen Brandt, Steffen Loft, Lise Marie Frohn, Jibran Khan, Susanne Brix, Morten A. Rasmussen, Jakob Stokholm, Bo Chawes, Andreanne Morin, Carole Ober, Hans Bisgaard, Marie Pedersen, Klaus Bønnelykke

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  • ·NLRP3 leucine-rich repeats control induced and spontaneous inflammasome activation in cryopyrin-associated periodic syndrome

    Página :222

    Katerina Theodoropoulou, Lotte Spel, Léa Zaffalon, Maeva Delacrétaz, Michaël Hofer, Fabio Martinon

    Resumen Resumen Esquema Esquema  
  • ·Epigenetic and immunological indicators of IPEX disease in subjects with FOXP3 gene mutation

    Página :233

    Mansi Narula, Uma Lakshmanan, Simon Borna, Janika J. Schulze, Tyson H. Holmes, Nicholas Harre, Matthew Kirkey, Akshaya Ramachandran, Veronica Maria Tagi, Federica Barzaghi, Eyal Grunebaum, Julia E.M. Upton, Vy Hong-Diep Kim, Christian Wysocki, Victoria R. Dimitriades, Kenneth Weinberg, Katja G. Weinacht, Yael Gernez, Bindu K. Sathi, Magdalena Schelotto, Matthew Johnson, Sven Olek, Christoph Sachsenmaier, Maria-Grazia Roncarolo, Rosa Bacchetta

    Resumen Resumen Esquema Esquema  

• Translational and clinical immunology

  • ·Combined IFN-γ and JAK inhibition to treat hemophagocytic lymphohistiocytosis in mice

    Página :247

    Josée-Anne Joly, Alexis Vallée, Benoîte Bourdin, Sara Bourbonnais, Natalie Patey, Louis Gaboury, Yves Théorêt, Hélène Decaluwe

    Resumen Resumen Esquema Esquema  
  • ·Aberrant T-cell exhaustion in severe combined immunodeficiency survivors with poor T-cell reconstitution after transplantation

    Página :260-271

    Roxane Labrosse, Ines Boufaied, Benoîte Bourdin, Saideep Gona, Haley E. Randolph, Brent R. Logan, Sara Bourbonnais, Chloé Berthe, Wendy Chan, Rebecca H. Buckley, Roberta E. Parrott, Geoffrey D.E. Cuvelier, Neena Kapoor, Sharat Chandra, Blachy J. Dávila Saldaña, Hesham Eissa, Fred D. Goldman, Jennifer Heimall, Richard O’Reilly, Sonali Chaudhury, Edward A. Kolb, Shalini Shenoy, Linda M. Griffith, Michael Pulsipher, Donald B. Kohn, Luigi D. Notarangelo, Sung-Yun Pai, Morton J. Cowan, Christopher C. Dvorak, Élie Haddad, Jennifer M. Puck, Luis B. Barreiro, Hélène Decaluwe

    Resumen Resumen Esquema Esquema   

• Epidemiology and health care delivery

  • ·A validated artificial intelligence-based pipeline for population-wide primary immunodeficiency screening

    Página :272-279

    Nicholas L. Rider, Michael Coffey, Ashok Kurian, Jessica Quinn, Jordan S. Orange, Vicki Modell, Fred Modell

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• Brief report

  • ·Azathioprine therapy induces selective NK cell depletion and IFN-γ deficiency predisposing to herpesvirus reactivation

    Página :280

    Florian Ingelfinger, Colin Sparano, David Bamert, David Reyes-Leiva, Aakriti Sethi, Lukas Rindlisbacher, Pascale Zwicky, Stefanie Kreutmair, Corinne C. Widmer, Sarah Mundt, Elena Cortés-Vicente, Sonia Tugues, Burkhard Becher, Bettina Schreiner

    Resumen Resumen Esquema Esquema  

• Correspondence

  • ·Cystatin SN—more than a type 2 immunity marker

    Página :287-288

    Bing Yan, Chengshuo Wang, Luo Zhang

     
  • ·Reply

    Página :288

    Benjamin S. Bleier