Índice

• • ·Cover 1

    Página :OFC

    
• • ·Brief Overview of This Month's JACI

    Página :5A

    
• • ·Table of Contents

    Página :7A

    
• • ·Editorial Board

    Página :37A

    

• Reader services

  • ·Information for Readers

    Página :38A

    
  • ·News & Notes

    Página :40A

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  • ·CME Activities Calendar

    Página :48A

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• News beyond our pages

  • ·News Beyond Our Pages

    Página :1429-1430

    Marc E. Rothenberg, Jean Bousquet

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• Reviews and feature articles

  • ·Current and future treatment options for adult chronic rhinosinusitis: Focus on nasal polyposis

    Página :1431-1440

    Claus Bachert, Luo Zhang, Phillippe Gevaert

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  • ·Current and future treatment options for adult chronic rhinosinusitis: Focus on nasal polyposis

    Página :1441

    
  • ·Chronic rhinosinusitis pathogenesis

    Página :1442-1453

    Whitney W. Stevens, Robert J. Lee, Robert P. Schleimer, Noam A. Cohen

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  • ·Drivers of chronic rhinosinusitis: Inflammation versus infection

    Página :1454-1459

    Daniel L. Hamilos

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  • ·Olfaction in allergic rhinitis: A systematic review

    Página :1460-1470

    Boris A. Stuck, Thomas Hummel

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  • ·The Journal of Allergy and Clinical Immunology: A 17-year perspective

    Página :1471

    Donald Y.M. Leung

     

• The Editors' choice

  • ·The Editors' Choice

    Página :1474-1475

    Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI

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• Asthma and lower airway disease

  • ·Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations

    Página :1476-1485

    Stephen J. Teach, Michelle A. Gill, Alkis Togias, Christine A. Sorkness, Samuel J. Arbes, Agustin Calatroni, Jeremy J. Wildfire, Peter J. Gergen, Robyn T. Cohen, Jacqueline A. Pongracic, Carolyn M. Kercsmar, Gurjit K. Khurana Hershey, Rebecca S. Gruchalla, Andrew H. Liu, Edward M. Zoratti, Meyer Kattan, Kristine A. Grindle, James E. Gern, William W. Busse, Stanley J. Szefler

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  • ·Acute and chronic systemic corticosteroid–related complications in patients with severe asthma

    Página :1488-1495

    Patrick Lefebvre, Mei Sheng Duh, Marie-Hélène Lafeuille, Laurence Gozalo, Urvi Desai, Marie-Noëlle Robitaille, Frank Albers, Steve Yancey, Hector Ortega, Mark Forshag, Xiwu Lin, Anand A. Dalal

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  • ·Use of asthma medication during pregnancy and risk of specific congenital anomalies: A European case-malformed control study

    Página :1496

    Ester Garne, Anne Vinkel Hansen, Joan Morris, Louise Zaupper, Marie-Claude Addor, Ingeborg Barisic, Miriam Gatt, Nathalie Lelong, Kari Klungsøyr, Mary O'Mahony, Vera Nelen, Amanda J. Neville, Anna Pierini, David Tucker, Hermien de Walle, Awi Wiesel, Maria Loane, Helen Dolk

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  • ·CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies

    Página :1503-1510

    Michael J. McGeachie, Ann C. Wu, Sze Man Tse, George L. Clemmer, Joanne Sordillo, Blanca E. Himes, Jessica Lasky-Su, Robert P. Chase, Fernando D. Martinez, Peter Weeke, Christian M. Shaffer, Hua Xu, Josh C. Denny, Dan M. Roden, Reynold A. Panettieri, Benjamin A. Raby, Scott T. Weiss, Kelan G. Tantisira

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  • ·Timing is everything: Targeting IgE to reduce asthma exacerbation risk

    Página :1486-1487

    Paul M. O'Byrne, Damian Tworek

    

• Rhinitis, sinusitis, and upper airway disease

  • ·Allergy immunotherapy for allergic rhinitis effectively prevents asthma: Results from a large retrospective cohort study

    Página :1511-1516

    Jochen Schmitt, Kristin Schwarz, Erich Stadler, Eike Gunther Wüstenberg

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  • ·Direct costs of adult chronic rhinosinusitis by using 4 methods of estimation: Results of the US Medical Expenditure Panel Survey

    Página :1517-1522

    Lisa Caulley, Kednapa Thavorn, Luke Rudmik, Chris Cameron, Shaun J. Kilty

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  • ·Immunoglobulin deficiency in patients with chronic rhinosinusitis: Systematic review of the literature and meta-analysis

    Página :1523-1531

    Adrien J.-P. Schwitzguébel, Peter Jandus, Jean-Silvain Lacroix, Jörg D. Seebach, Thomas Harr

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  • ·Patient-reported outcome measures for adult chronic rhinosinusitis: A systematic review and quality assessment

    Página :1532

    Luke Rudmik, Claire Hopkins, Anju Peters, Timothy L. Smith, Rodney J. Schlosser, Zachary M. Soler

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  • ·Randomized controlled trial of primary prevention of atopy using house dust mite allergen oral immunotherapy in early childhood

    Página :1541

    Zaraquiza Zolkipli, Graham Roberts, Victoria Cornelius, Bernie Clayton, Sarah Pearson, Louise Michaelis, Ratko Djukanovic, Ramesh Kurukulaaratchy, S. Hasan Arshad

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  • ·Increased expression of the epithelial anion transporter pendrin/SLC26A4 in nasal polyps of patients with chronic rhinosinusitis

    Página :1548

    Sudarshan Seshadri, Xiang Lu, Matthew R. Purkey, Tetsuya Homma, Andrew Wonho Choi, Roderick Carter, Lydia Suh, James Norton, Kathleen E. Harris, David B. Conley, Atsushi Kato, Pedro C. Avila, Barbara Czarnocka, Peter A. Kopp, Anju T. Peters, Leslie C. Grammer, Rakesh K. Chandra, Bruce K. Tan, Zheng Liu, Robert C. Kern, Robert P. Schleimer

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  • ·Allergic sensitization is age-dependently associated with rhinitis, but less so with asthma

    Página :1559

    Katja Warm, Linnea Hedman, Anne Lindberg, Jan Lötvall, Bo Lundbäck, Eva Rönmark

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  • ·Preventive effect of nasal filters on allergic rhinitis: A randomized, double-blind, placebo-controlled crossover park study

    Página :1566

    Peter Kenney, Ole Hilberg, Anne Cathrine Laursen, Robert George Peel, Torben Sigsgaard

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• Atopic dermatitis and skin disease

  • ·Filaggrin breakdown products determine corneocyte conformation in patients with atopic dermatitis

    Página :1573

    Christoph Riethmuller, Maeve A. McAleer, Sjors A. Koppes, Rawad Abdayem, Jonas Franz, Marek Haftek, Linda E. Campbell, Stephanie F. MacCallum, W.H. Irwin McLean, Alan D. Irvine, Sanja Kezic

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  • ·Large maculopapular cutaneous lesions are associated with favorable outcome in childhood-onset mastocytosis

    Página :1581

    Tim Wiechers, Anja Rabenhorst, Tina Schick, Liane M. Preussner, Anja Förster, Peter Valent, Hans-Peter Horny, Karl Sotlar, Karin Hartmann

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  • ·Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum

    Página :1591-1600

    Li Gao, Lianghua Bin, Nicholas M. Rafaels, Lili Huang, Joseph Potee, Ingo Ruczinski, Terri H. Beaty, Amy S. Paller, Lynda C. Schneider, Rich Gallo, Jon M. Hanifin, Lisa A. Beck, Raif S. Geha, Rasika A. Mathias, Kathleen C. Barnes, Donald Y.M. Leung

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• Food, drug, insect sting allergy, and anaphylaxis

  • ·Efficacy of baked milk oral immunotherapy in baked milk–reactive allergic patients

    Página :1601-1606

    Michael R. Goldberg, Liat Nachshon, Michael Y. Appel, Arnon Elizur, Michael B. Levy, Eli Eisenberg, Hugh A. Sampson, Yitzhak Katz

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  • ·Usefulness of recombinant ?-gliadin 1 for identifying patients with celiac disease and monitoring adherence to a gluten-free diet

    Página :1607

    Bharani Srinivasan, Margarete Focke-Tejkl, Milena Weber, Sandra Pahr, Alexandra Baar, Raja Atreya, Markus F. Neurath, Harald Vogelsang, Wolf-Dietrich Huber, Rudolf Valenta

    Resumen Resumen Esquema Esquema  

• Immune deficiencies, infection, and systemic immune disorders

  • ·An in vivo genetic reversion highlights the crucial role of Myb-Like, SWIRM, and MPN domains 1 (MYSM1) in human hematopoiesis and lymphocyte differentiation

    Página :1619

    Tangui Le Guen, Fabien Touzot, Isabelle André-Schmutz, Chantal Lagresle-Peyrou, Benoit France, Laetitia Kermasson, Nathalie Lambert, Capucine Picard, Patrick Nitschke, Wassila Carpentier, Christine Bole-Feysot, Annick Lim, Marina Cavazzana, Isabelle Callebaut, Jean Soulier, Nada Jabado, Alain Fischer, Jean-Pierre de Villartay, Patrick Revy

    Resumen Resumen Esquema Esquema  

• Mechanisms of allergy and clinical immunology

  • ·Chronic cat allergen exposure induces a T_H2 cell–dependent IgG₄ response related to low sensitization

    Página :1627

    Amedee Renand, Luis D. Archila, John McGinty, Erik Wambre, David Robinson, Belinda J. Hales, Wayne R. Thomas, William W. Kwok

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  • ·Thymic stromal lymphopoietin activation of basophils in patients with allergic asthma is IL-3 dependent

    Página :1636-1644

    Brittany M. Salter, John Paul Oliveria, Graeme Nusca, Steve G. Smith, Rick M. Watson, Micheal Comeau, Roma Sehmi, Gail M. Gauvreau

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  • ·Evolution pathways of IgE responses to grass and mite allergens throughout childhood

    Página :1645

    Adnan Custovic, Hans-Joachim Sonntag, Iain E. Buchan, Danielle Belgrave, Angela Simpson, Mattia C.F. Prosperi

    Resumen Resumen Esquema Esquema  
  • ·IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation

    Página :1653

    Ben Roediger, Ryan Kyle, Szun S. Tay, Andrew J. Mitchell, Holly A. Bolton, Thomas V. Guy, Sioh-Yang Tan, Elizabeth Forbes-Blom, Philip L. Tong, Yasmin Köller, Elena Shklovskaya, Makio Iwashima, Kathy D. McCoy, Graham Le Gros, Barbara Fazekas de St Groth, Wolfgang Weninger

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  • ·Genome-wide interaction study of gene-by-occupational exposure and effects on FEV₁ levels

    Página :1664

    Kim de Jong, Judith M. Vonk, Wim Timens, Yohan Bossé, Don D. Sin, Ke Hao, Hans Kromhout, Roel Vermeulen, Dirkje S. Postma, H. Marike Boezen

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  • ·Assessment of clinical findings, tryptase levels, and bone marrow histopathology in the management of pediatric mastocytosis

    Página :1673

    Melody C. Carter, Sarah T. Clayton, Hirsh D. Komarow, Erica H. Brittain, Linda M. Scott, Daly Cantave, Donna M. Gaskins, Irina Maric, Dean D. Metcalfe

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• Letters to the Editor

  • ·The diversity of Bet v 1–specific IgG₄ antibodies remains mostly constant during the course of birch pollen immunotherapy

    Página :1680

    Brinda Subbarayal, Dirk Schiller, Christian Möbs, Wolfgang Pfützner, Beatrice Jahn-Schmid, Barbara Gepp, Heimo Breiteneder, Stefan Vieths, Barbara Bohle

     
  • ·Host, disease, and antiretroviral factors are associated with normalization of the CD4:CD8 ratio after initiating antiretroviral therapy

    Página :1682

    Alan Winston, Sophie Jose, Martin Fisher, John Walsh, Mark Nelson, Richard Gilson, Frank Post, Margaret Johnson, Clifford Leen, David Chadwick, Phillip Hay, Jillian Pritchard, Anjum Tariq, Caroline Sabin, UK Collaborative HIV Cohort Study

    
  • ·Mite allergen–specific IgE is detectable in bronchial secretions of patients with nonatopic asthma and correlates with mucosal expression of periostin

    Página :1685

    Jonathan Mouthuy, Sophie Viart, Maha Z. Ladjemi, Bruno Detry, Monique Henket, Claus Bachert, Renaud Louis, Charles Pilette

      
  • ·Furry pets modulate gut microbiota composition in infants at risk for allergic disease

    Página :1688

    Merja Nermes, Akihito Endo, Jasmin Aarnio, Seppo Salminen, Erika Isolauri

     
  • ·Neuropeptide signaling through neurokinin-1 and neurokinin-2 receptors augments antigen presentation by human dendritic cells

    Página :1690-1694

    Junya Ohtake, Shun Kaneumi, Mishie Tanino, Takuto Kishikawa, Satoshi Terada, Kentaro Sumida, Kazutaka Masuko, Yosuke Ohno, Toshiyuki Kita, Sadahiro Iwabuchi, Toshiya Shinohara, Yoshinori Tanino, Tamiko Takemura, Shinya Tanaka, Hiroya Kobayashi, Hidemitsu Kitamura

      
  • ·Claudin 5 in a murine model of allergic asthma: Its implication and response to steroid treatment

    Página :1694

    Kuk-Young Moon, Pureun-Haneul Lee, Byeong-Gon Kim, Choon-Sik Park, George D. Leikauf, An-Soo Jang

     
  • ·Immunoactive prebiotics transiently prevent occurrence of early atopic dermatitis among low-atopy-risk infants

    Página :1696

    Christoph Grüber, Margriet van Stuivenberg, Fabio Mosca, Guido Moro, Gaetano Chirico, Christian P. Braegger, Josef Riedler, Yalcin Yavuz, Günther Boehm, Ulrich Wahn, MIPS II Working Group

     
  • ·Critical link between glycogen synthase kinase 3? and forkhead box P3 in patients with chronic rhinosinusitis with nasal polyps

    Página :1698

    Xingmei Wu, Sihua Wang, Miaomiao Han, Bin Song, Ping Ye, Shanshan Ma, Jun Li, Fenghong Chen, Geng Xu, Qingqing Ding, Jiahong Xia, Huabin Li

     
  • ·Association of periostin expression with eosinophilic inflammation in nasal polyps

    Página :1700

    Min Wang, Xiangdong Wang, Nan Zhang, Hong Wang, Ying Li, Erzhong Fan, Liang Zhang, Luo Zhang, Claus Bachert

     
  • ·Defective nuclear entry of hydrolases prevents neutrophil extracellular trap formation in patients with chronic granulomatous disease

    Página :1703

    Susana Romao, Emilio Tejera Puente, Katarzyna J. Nytko, Ulrich Siler, Christian Münz, Janine Reichenbach

     

• Correspondence

  • ·Leprosy is teaching us the immunopathogenesis of inflammatory skin disease

    Página :1707

    Tina Rendini, William Levis

    
  • ·Reply

    Página :1707-1708

    Tali Czarnowicki, James G. Krueger, Emma Guttman-Yassky

    
  • ·The common food additive carrageenan and the alpha-gal epitope

    Página :1708-1709

    Joanne K. Tobacman

     
  • ·Reply

    Página :1709-1710

    John W. Steinke, Thomas A.E. Platts-Mills, Alex Schuyler, Scott P. Commins

    

• Corrections

  • ·Corrections

    Página :1710

    
  • ·Correction

    Página :1710

    
  • ·Correction

    Página :1710

    

• Maintenance of Certification clinical management series

  • ·Factors influencing growth effects of inhaled corticosteroids in children

    Página :1711

    Peter M. Wolfgram, David B. Allen

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