Índice

• • ·Cover 1

    Página :OFC

    
• • ·Brief Overview of This Month's JACI

    Página :5A

    
• • ·Table of Contents

    Página :7A

    
• • ·Editorial Board

    Página :21A

    

• Reader services

  • ·Information for Readers

    Página :22A

    
  • ·News & Notes

    Página :24A

    Esquema Esquema  
  • ·CME Activities Calendar

    Página :28A

    Esquema Esquema

• News beyond our pages

  • ·News Beyond Our Pages

    Página :1-2

    Marc E. Rothenberg, Jean Bousquet

    Esquema Esquema  

• Reviews and feature articles

  • ·The allergy epidemics: 1870-2010

    Página :3-13

    Thomas A.E. Platts-Mills

    Resumen Resumen Esquema Esquema  
  • ·The allergy epidemics: 1870-2010

    Página :14

    
  • ·The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stage

    Página :15-22

    Patrick G. Holt

    Resumen Resumen Esquema Esquema  
  • ·Promising candidates for allergy prevention

    Página :23-28

    James E. Gern

    Resumen Resumen Esquema Esquema  
  • ·100 Years later: Celebrating the contributions of x-ray crystallography to allergy and clinical immunology

    Página :29

    Anna Pomés, Maksymilian Chruszcz, Alla Gustchina, Wladek Minor, Geoffrey A. Mueller, Lars C. Pedersen, Alexander Wlodawer, Martin D. Chapman

    Resumen Resumen Esquema Esquema  
  • ·Respiratory allergy caused by house dust mites: What do we really know?

    Página :38-48

    Moisés A. Calderón, Allan Linneberg, Jörg Kleine-Tebbe, Frédéric De Blay, Dolores Hernandez Fernandez de Rojas, Johann Christian Virchow, Pascal Demoly

    Resumen Resumen Esquema Esquema  

• The Editors' choice

  • ·The Editors' Choice

    Página :49-50

    Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI

    Esquema Esquema  

• Asthma and lower airway disease

  • ·Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40

    Página :51

    Jose L. Gomez, Gina M. Crisafi, Carole T. Holm, Deborah A. Meyers, Gregory A. Hawkins, Eugene R. Bleecker, Nizar Jarjour, Severe Asthma Research Program (SARP) Investigators, Lauren Cohn, Geoffrey L. Chupp

    Resumen Resumen Esquema Esquema  
  • ·Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33

    Página :59

    Christina A. Christianson, Nicholas P. Goplen, Iram Zafar, Chaoyu Irvin, James T. Good, Donald R. Rollins, Balachandra Gorentla, Weimin Liu, Magdalena M. Gorska, HongWei Chu, Richard J. Martin, Rafeul Alam

    Resumen Resumen Esquema Esquema  
  • ·DNA methylation and childhood asthma in the inner city

    Página :69-80

    Ivana V. Yang, Brent S. Pedersen, Andrew Liu, George T. O'Connor, Stephen J. Teach, Meyer Kattan, Rana Tawil Misiak, Rebecca Gruchalla, Suzanne F. Steinbach, Stanley J. Szefler, Michelle A. Gill, Agustin Calatroni, Gloria David, Corinne E. Hennessy, Elizabeth J. Davidson, Weiming Zhang, Peter Gergen, Alkis Togias, William W. Busse, David A. Schwartz

    Resumen Resumen Esquema Esquema   
  • ·Association between respiratory infections in early life and later asthma is independent of virus type

    Página :81

    Klaus Bønnelykke, Nadja Hawwa Vissing, Astrid Sevelsted, Sebastian L. Johnston, Hans Bisgaard

    Resumen Resumen Esquema Esquema  

• Rhinitis, sinusitis, and upper airway disease

  • ·Variation of the group 5 grass pollen allergen content of airborne pollen in relation to geographic location and time in season

    Página :87

    Jeroen Buters, Marje Prank, Mikhail Sofiev, Gudrun Pusch, Roberto Albertini, Isabella Annesi-Maesano, Celia Antunes, Heidrun Behrendt, Uwe Berger, Rui Brandao, Sevcan Celenk, Carmen Galan, ?ukasz Grewling, Bogdan Jackowiak, Roy Kennedy, Auli Rantio-Lehtimäki, Gerald Reese, Ingrida Sauliene, Matt Smith, Michel Thibaudon, Bernhard Weber, Lorenzo Cecchi

    Resumen Resumen Esquema Esquema  

• Atopic dermatitis and skin disease

  • ·Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber

    Página :96

    Thomas Werfel, Annice Heratizadeh, Margarete Niebuhr, Alexander Kapp, Lennart Matthias Roesner, Annika Karch, Veit J. Erpenbeck, Christian Lösche, Thomas Jung, Norbert Krug, Philipp Badorrek, Jens M. Hohlfeld

    Resumen Resumen Esquema Esquema  
  • ·Severe atopic dermatitis is characterized by selective expansion of circulating T_H2/T_C2 and T_H22/T_C22, but not T_H17/T_C17, cells within the skin-homing T-cell population

    Página :104

    Tali Czarnowicki, Juana Gonzalez, Avner Shemer, Dana Malajian, Hui Xu, Xiuzhong Zheng, Saakshi Khattri, Patricia Gilleaudeau, Mary Sullivan-Whalen, Mayte Suárez-Fariñas, James G. Krueger, Emma Guttman-Yassky

    Resumen Resumen Esquema Esquema  
  • ·Anti–IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose, randomized, double-blind, placebo-controlled trial

    Página :116

    James G. Krueger, Laura K. Ferris, Alan Menter, Frank Wagner, Alexander White, Sudha Visvanathan, Bojan Lalovic, Stella Aslanyan, Elaine E.L. Wang, David Hall, Alan Solinger, Steven Padula, Paul Scholl

    Resumen Resumen Esquema Esquema  

• Food, drug, insect sting allergy, and anaphylaxis

  • ·Peanut oral immunotherapy transiently expands circulating Ara h 2–specific B cells with a homologous repertoire in unrelated subjects

    Página :125

    Sarita U. Patil, Adebola O. Ogunniyi, Agustin Calatroni, Vasisht R. Tadigotla, Bert Ruiter, Alex Ma, James Moon, J. Christopher Love, Wayne G. Shreffler

    Resumen Resumen Esquema Esquema  
  • ·Clonal mast cell disorders in patients with severe Hymenoptera venom allergy and normal serum tryptase levels

    Página :135-139

    Roberta Zanotti, Carla Lombardo, Giovanni Passalacqua, Cristian Caimmi, Massimiliano Bonifacio, Giovanna De Matteis, Omar Perbellini, Maurizio Rossini, Donatella Schena, Moira Busa, Maria Cinzia Marcotulli, Maria Beatrice Bilò, Maurizio Franchini, Giovanni Marchi, Livio Simioni, Patrizia Bonadonna

    Resumen Resumen Esquema Esquema  

• Immune deficiencies, infection, and systemic immune disorders

  • ·Functional analysis of naturally occurring DCLRE1C mutations and correlation with the clinical phenotype of ARTEMIS deficiency

    Página :140

    Kerstin Felgentreff, Yu Nee Lee, Francesco Frugoni, Likun Du, Mirjam van der Burg, Silvia Giliani, Ilhan Tezcan, Ismail Reisli, Ester Mejstrikova, Jean-Pierre de Villartay, Barry P. Sleckman, John Manis, Luigi D. Notarangelo

    Resumen Resumen Esquema Esquema  

• Mechanisms of allergy and clinical immunology

  • ·Correlation of sensitizing capacity and T-cell recognition within the Bet v 1 family

    Página :151-158

    Claudia Kitzmüller, Nora Zulehner, Anargyros Roulias, Peter Briza, Fatima Ferreira, Ingrid Faé, Gottfried F. Fischer, Barbara Bohle

    Resumen Resumen Esquema Esquema  
  • ·Activated glycoprotein A repetitions predominant (GARP)–expressing regulatory T cells inhibit allergen-induced intestinal inflammation in humanized mice

    Página :159-168

    Melanie Eschborn, Benno Weigmann, Sonja Reissig, Ari Waisman, Joachim Saloga, Iris Bellinghausen

    Resumen Resumen Esquema Esquema  
  • ·The long-term programming effect of maternal 25-hydroxyvitamin D in pregnancy on allergic airway disease and lung function in offspring after 20 to 25 years of follow-up

    Página :169

    Susanne Hansen, Ekaterina Maslova, Marin Strøm, Allan Linneberg, Thorhallur I. Halldorsson, Charlotta Granström, Ronald Dahl, Hans Jürgen Hoffmann, Sjurdur F. Olsen

    Resumen Resumen Esquema Esquema  
  • ·Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons

    Página :177

    Vera Gielen, Annemarie Sykes, Jie Zhu, Brian Chan, Jonathan Macintyre, Nicolas Regamey, Elisabeth Kieninger, Atul Gupta, Amelia Shoemark, Cara Bossley, Jane Davies, Sejal Saglani, Patrick Walker, Sandra E. Nicholson, Alexander H. Dalpke, Onn-Min Kon, Andrew Bush, Sebastian L. Johnston, Michael R. Edwards

    Resumen Resumen Esquema Esquema  

• Letters to the Editor

  • ·International prevalence rates of asthma and allergy are associated with income inequality

    Página :189

    Eleonora P. Uphoff, Báltica Cabieses, John Wright, Kate E. Pickett

     
  • ·Atopic dermatitis disease control and age: A cohort study

    Página :190

    Katrina Abuabara, Ole Hoffstad, Andrea Troxel, Joel M. Gelfand, David J. Margolis

     
  • ·Sensitization to cashew nut 2S albumin, Ana o 3, is highly predictive of cashew and pistachio allergy in Greek children

    Página :192-194

    Savvas Savvatianos, Anastasios P. Konstantinopoulos, Åse Borgå, George Stavroulakis, Jonas Lidholm, Magnus P. Borres, Emmanouil Manousakis, Nikolaos G. Papadopoulos

      
  • ·T-cell regulation during viral and nonviral asthma exacerbations

    Página :194

    Agnieszka S. Wegrzyn, Bogdan Jakiela, Beate Rückert, Marek Jutel, Mübeccel Akdis, Marek Sanak, Cezmi A. Akdis

     
  • ·Prevention of allergic asthma through Der p 2 peptide vaccination

    Página :197

    Gregory Bouchaud, Faouzi Braza, Julie Chesné, David Lair, Kuan-Wei Chen, Camille Rolland-Debord, Dorian Hassoun, Tiphaine Roussey-Bihouée, Marie-Aude Cheminant, Sophie Brouard, Marie Bodinier, Susanne Vrtala, Antoine Magnan

     
  • ·Childhood allergic asthma is associated with increased IL-13 and FOXP3 histone acetylation

    Página :200-202

    Hani Harb, Diana Raedler, Nikolaus Ballenberger, Andreas Böck, Dörthe A. Kesper, Harald Renz, Bianca Schaub

     
  • ·IL-13 mediates IL-33–dependent mast cell and type 2 innate lymphoid cell effects on bronchial epithelial cells

    Página :202-205

    Deepti R. Nagarkar, Vladimir Ramirez-Carrozzi, David F. Choy, Kevin Lee, Robert Soriano, Guiquan Jia, Alexander R. Abbas, Zora Modrusan, Rajita Pappu, Joseph R. Arron

      
  • ·Thymic stromal lymphopoietin downregulates filaggrin expression by signal transducer and activator of transcription 3 (STAT3) and extracellular signal-regulated kinase (ERK) phosphorylation in keratinocytes

    Página :205

    Jin Hee Kim, Hyun Cheol Bae, Na Young Ko, See Hyun Lee, Sang Hoon Jeong, Hana Lee, Woo-In Ryu, Young Chul Kye, Sang Wook Son

     
  • ·Skin-homing and systemic T-cell subsets show higher activation in atopic dermatitis versus psoriasis

    Página :208-211

    Tali Czarnowicki, Dana Malajian, Avner Shemer, Judilyn Fuentes-Duculan, Juana Gonzalez, Mayte Suárez-Fariñas, James G. Krueger, Emma Guttman-Yassky

      
  • ·Nasal endoscopy to characterize sinonasal disease

    Página :212

    Brian Lipworth

    
  • ·Reply

    Página :212-213

    Anne E. Dixon, Mario Castro, Rubin I. Cohen, Lynn B. Gerald, Janet T. Holbrook, Charles G. Irvin, Shyam Mohapatra, Stephen P. Peters, Sobharani Rayapudi, Elizabeth A. Sugar, Robert A. Wise, American Lung Association–Asthma Clinical Research Centers

    
  • ·Significance of extravascular reservoirs of latent infection for HIV persistence during antiretroviral therapy

    Página :213

    J. Bruce Sundstrom

    
  • ·Reply

    Página :214

    Janet D. Siliciano, Robert F. Siliciano

    
  • ·In lasting tribute: Professor Dr I?il Berat Barlan (1958-2015)

    Página :215

    Cezmi Akdis, Mübeccel Akdis, Talal A. Chatila, Günnur Deniz, Raif S. Geha, Michael J. Lenardo, Hans C. Oettgen