Índice

• • ·Cover 1

    Página :OFC

    
• • ·Brief Overview of This Month's JACI

    Página :3A

    
• • ·Table of Contents

    Página :8A

    
• • ·Editorial Board

    Página :30A

    

• Reader services

  • ·Information for Readers

    Página :32A

    
  • ·News & Notes

    Página :34A

    Esquema Esquema  
  • ·CME Activities Calendar

    Página :40A

    Esquema Esquema

• News beyond our pages

  • ·News Beyond Our Pages

    Página :1017-1018

    Marc E. Rothenberg, Jean Bousquet, Patricia C. Fulkerson

    Esquema Esquema  

• Reviews and feature articles

  • ·Glucocorticoid-induced osteoporosis: An update on effects and management

    Página :1019-1030

    Bjoern Buehring, Ravi Viswanathan, Neil Binkley, William Busse

    Resumen Resumen Esquema Esquema  
  • ·Glucocorticoid-induced osteoporosis: An update on effects and management

    Página :1031-1032

    
  • ·The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease

    Página :1033-1044

    Robert H. Oakley, John A. Cidlowski

    Resumen Resumen Esquema Esquema  
  • ·Inhaled allergen bronchoprovocation tests

    Página :1045

    Zuzana Diamant, Gail M. Gauvreau, Don W. Cockcroft, Louis-Philippe Boulet, Peter J. Sterk, Frans H.C. de Jongh, Barbro Dahlén, Paul M. O’Byrne

    Resumen Resumen Esquema Esquema  

• The Editors' choice

  • ·The Editors' Choice

    Página :1056-1057

    Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI

    Esquema Esquema  

• Asthma and lower airway disease

  • ·Comparison of phenotypes of childhood wheeze and cough in 2 independent cohorts

    Página :1058-1067

    Ben D. Spycher, Michael Silverman, Anina M. Pescatore, Caroline S. Beardsmore, Claudia E. Kuehni

    Resumen Resumen Esquema Esquema   
  • ·Predictors of response to tiotropium versus salmeterol in asthmatic adults

    Página :1068

    Stephen P. Peters, Eugene R. Bleecker, Susan J. Kunselman, Nikolina Icitovic, Wendy C. Moore, Rodolfo Pascual, Bill T. Ameredes, Homer A. Boushey, William J. Calhoun, Mario Castro, Reuben M. Cherniack, Timothy Craig, Loren C. Denlinger, Linda L. Engle, Emily A. DiMango, Elliot Israel, Monica Kraft, Stephen C. Lazarus, Robert F. Lemanske, Njira Lugogo, Richard J. Martin, Deborah A. Meyers, Joe Ramsdell, Christine A. Sorkness, E. Rand Sutherland, Stephen I. Wasserman, Michael J. Walter, Michael E. Wechsler, Vernon M. Chinchilli, Stanley J. Szefler, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network

    Resumen Resumen Esquema Esquema  
  • ·Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor ?B and c-Jun N-terminal kinase activation

    Página :1075

    Alberto Papi, Marco Contoli, Ian M. Adcock, Cinzia Bellettato, Anna Padovani, Paolo Casolari, Luminita A. Stanciu, Peter J. Barnes, Sebastian L. Johnston, Kazuhiro Ito, Gaetano Caramori

    Resumen Resumen Esquema Esquema  
  • ·Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia

    Página :1086

    Michel Laviolette, David L. Gossage, Gail Gauvreau, Richard Leigh, Ron Olivenstein, Rohit Katial, William W. Busse, Sally Wenzel, Yanping Wu, Vivekananda Datta, Roland Kolbeck, Nestor A. Molfino

    Resumen Resumen Esquema Esquema  
  • ·Eosinophilic asthma: Insights into the effects of reducing IL-5 receptor–positive cell levels

    Página :1097-1098

    Amal H. Assa'ad, Marc E. Rothenberg

    

• Rhinitis, sinusitis, and upper airway disease

  • ·Association of indoor dampness and molds with rhinitis risk: A systematic review and meta-analysis

    Página :1099

    Maritta S. Jaakkola, Reginald Quansah, Timo T. Hugg, Sirpa A.M. Heikkinen, Jouni J.K. Jaakkola

    Resumen Resumen Esquema Esquema  

• Atopic dermatitis and skin disease

  • ·A homozygous nonsense mutation in the gene for Tmem79, a component for the lamellar granule secretory system, produces spontaneous eczema in an experimental model of atopic dermatitis

    Página :1111

    Takashi Sasaki, Aiko Shiohama, Akiharu Kubo, Hiroshi Kawasaki, Akemi Ishida-Yamamoto, Taketo Yamada, Takayuki Hachiya, Atsushi Shimizu, Hideyuki Okano, Jun Kudoh, Masayuki Amagai

    Resumen Resumen Esquema Esquema   
  • ·Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

    Página :1121-1129

    Sean P. Saunders, Christabelle S.M. Goh, Sara J. Brown, Colin N.A. Palmer, Rebecca M. Porter, Christian Cole, Linda E. Campbell, Marek Gierlinski, Geoffrey J. Barton, Georg Schneider, Allan Balmain, Alan R. Prescott, Stephan Weidinger, Hansjörg Baurecht, Michael Kabesch, Christian Gieger, Young-Ae Lee, Roger Tavendale, Somnath Mukhopadhyay, Stephen W. Turner, Vishnu B. Madhok, Frank M. Sullivan, Caroline Relton, John Burn, Simon Meggitt, Catherine H. Smith, Michael A. Allen, Jonathan N.W. N. Barker, Nick J. Reynolds, Heather J. Cordell, Alan D. Irvine, W.H. Irwin McLean, Aileen Sandilands, Padraic G. Fallon

    Resumen Resumen Esquema Esquema   
  • ·Adult eczema prevalence and associations with asthma and other health and demographic factors: A US population–based study

    Página :1132-1138

    Jonathan I. Silverberg, Jon M. Hanifin

    Resumen Resumen Esquema Esquema  
  • ·Atopic dermatitis: Scratching through the complexity of barrier dysfunction

    Página :1130-1131

    Eli Sprecher, Donald Y.M. Leung

    Esquema Esquema
  • ·Do children really outgrow their eczema, or is there more than one eczema?

    Página :1139-1140

    Katrina Abuabara, David J. Margolis

    

• Food, drug, insect sting allergy, and anaphylaxis

  • ·Anaphylaxis: Clinical patterns, mediator release, and severity

    Página :1141

    Simon G.A. Brown, Shelley F. Stone, Daniel M. Fatovich, Sally A. Burrows, Anna Holdgate, Antonio Celenza, Adam Coulson, Leanne Hartnett, Yusuf Nagree, Claire Cotterell, Geoffrey K. Isbister

    Resumen Resumen Esquema Esquema  

• Immune deficiencies, infection, and systemic immune disorders

  • ·Clinical outcome in children with chronic granulomatous disease managed conservatively or with hematopoietic stem cell transplantation

    Página :1150-1155

    Theresa Cole, Mark S. Pearce, Andrew J. Cant, Catherine M. Cale, David Goldblatt, Andrew R. Gennery

    Resumen Resumen Esquema Esquema
  • ·Clinical, functional, and genetic characterization of chronic granulomatous disease in 89 Turkish patients

    Página :1156

    Mustafa Yavuz Köker, Y?ld?z Camc?o?lu, Karin van Leeuwen, Sara ?ebnem K?l?ç, I??l Barlan, Mustafa Y?lmaz, Ay?e Metin, Martin de Boer, Hüseyin Avc?lar, Türkan Pat?ro?lu, Ali?an Y?ld?ran, Olcay Ye?in, ?lhan Tezcan, Özden Sanal, Dirk Roos

    Resumen Resumen Esquema Esquema  
  • ·The long road to optimal management for chronic granulomatous disease

    Página :1164-1165

    Luigi D. Notarangelo

    

• Mechanisms of allergy and clinical immunology

  • ·Inhaled long-acting ?₂ agonists enhance glucocorticoid receptor nuclear translocation and efficacy in sputum macrophages in COPD

    Página :1166-1173

    Rubaiyat Haque, Amir Hakim, Thunicia Moodley, Alfonso Torrego, Sarah Essilfie-Quaye, Elen Jazrawi, Malcolm Johnson, Peter J. Barnes, Ian M. Adcock, Omar Sharif Usmani

    Resumen Resumen Esquema Esquema  
  • ·The steroidogenic enzyme Cyp11a1 is essential for development of peanut-induced intestinal anaphylaxis

    Página :1174

    Meiqin Wang, Julita Ramirez, Junyan Han, Yi Jia, Joanne Domenico, Max A. Seibold, James R. Hagman, Erwin W. Gelfand

    Resumen Resumen Esquema Esquema  
  • ·Infliximab induces downregulation of the IL-12/IL-23 axis in 6-sulfo-LacNac (slan)⁺ dendritic cells and macrophages

    Página :1184

    Patrick M. Brunner, Frieder Koszik, Bärbel Reininger, Madeleine L. Kalb, Wolfgang Bauer, Georg Stingl

    Resumen Resumen Esquema Esquema  
  • ·Diesel exhaust particle induction of IL-17A contributes to severe asthma

    Página :1194

    Eric B. Brandt, Melinda Butsch Kovacic, Gerald B. Lee, Aaron M. Gibson, Thomas H. Acciani, Timothy D. Le Cras, Patrick H. Ryan, Alison L. Budelsky, Gurjit K. Khurana Hershey

    Resumen Resumen Esquema Esquema  
  • ·Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice

    Página :1205

    Hong Cui, Yasuo Okamoto, Kazuaki Yoshioka, Wa Du, Noriko Takuwa, Wei Zhang, Masahide Asano, Toshishige Shibamoto, Yoh Takuwa

    Resumen Resumen Esquema Esquema  

• Letters to the Editor

  • ·Tolerance of baked milk in patients with cow's milk–mediated eosinophilic esophagitis

    Página :1215

    John Leung, Navneet Virk Hundal, Aubrey J. Katz, Wayne G. Shreffler, Qian Yuan, Carolyn A. Butterworth, Paul E. Hesterberg

     
  • ·Prevalence of self-reported food allergy in the National Health and Nutrition Examination Survey (NHANES) 2007-2010

    Página :1216

    Emily C. McGowan, Corinne A. Keet

    
  • ·Use of ondansetron for food protein–induced enterocolitis syndrome

    Página :1219-1220

    Teri Holbrook, Corinne A. Keet, Pamela A. Frischmeyer-Guerrerio, Robert A. Wood

    
  • ·Outcomes of the Childhood Asthma Prevention Study at 11.5 years

    Página :1220

    Brett G. Toelle, Frances L. Garden, Kitty K.W. Ng, Elena G. Belousova, Catarina Almqvist, Chris T. Cowell, Euan R. Tovey, Karen L. Webb, Stephen R. Leeder, Guy B. Marks, Childhood Asthma Prevention Study Team

     
  • ·Age-stratified comparison of large and peripheral airway/alveolar nitric oxide levels in children and young adults

    Página :1222-1224

    Arthur F. Gelb, Deepak H. Singh, Roxanna Moridzadeh, Christine Fraser, Diem Tran, Sylvia Verbanck, Steven C. George

    
  • ·Lower levels of hsa-mir-15a, which decreases VEGFA, in the CD4⁺ T cells of pediatric patients with asthma

    Página :1224

    Taiji Nakano, Yuzaburo Inoue, Naoki Shimojo, Fumiya Yamaide, Yoshinori Morita, Takayasu Arima, Minako Tomiita, Yoichi Kohno

     
  • ·Regional differences in the expression of innate host defense molecules in sinonasal mucosa

    Página :1227

    Sudarshan Seshadri, Mariel Rosati, David C. Lin, Roderick G. Carter, James E. Norton, Andrew Wonho Choi, Lydia Suh, Atsushi Kato, Rakesh K. Chandra, Kathleen E. Harris, Hong Wei Chu, Anju T. Peters, Bruce K. Tan, David B. Conley, Leslie C. Grammer, Robert C. Kern, Robert P. Schleimer

     
  • ·National burden of antibiotic use for adult rhinosinusitis

    Página :1230-1232

    Stephanie Shintani Smith, Charlesnika T. Evans, Bruce K. Tan, Rakesh K. Chandra, Sean B. Smith, Robert C. Kern

     
  • ·Racial comparison of filaggrin null mutations in asthmatic patients with atopic dermatitis in a US population

    Página :1232-1234

    Jackie P.-D. Garrett, Ole Hoffstad, Andrea J. Apter, David J. Margolis

    
  • ·Serum levels of bone cytokines are increased in indolent systemic mastocytosis associated with osteopenia or osteoporosis

    Página :1234

    Anja Rabenhorst, Bastian Christopeit, Silke Leja, Alexander Gerbaulet, Svea Kleiner, Anja Förster, Ulrike Raap, Claudia Wickenhauser, Karin Hartmann

     
  • ·Interaction between atopy and blood eosinophils in the development of childhood wheeze

    Página :1237

    Jon Genuneit

     
  • ·Become a farmer and avoid new allergic sensitization: Adult farming exposures protect against new-onset atopic sensitization

    Página :1239-1241

    Grethe Elholm, Vivi Schlünssen, Gert Doekes, Ioannis Basinas, Bo Martin Bibby, Charlotte Hjort, Pernille Milvang Grønager, Øyvind Omland, Torben Sigsgaard

    
  • ·Rhinovirus specific IgE can be detected in human sera

    Página :1241-1243

    Jonathan S. Tam, William T. Jackson, Desire Hunter, David Proud, Mitchell H. Grayson

     
  • ·Deficient glucocorticoid induction of anti-inflammatory genes in nasal polyp fibroblasts of asthmatic patients with and without aspirin intolerance

    Página :1243

    Laura Fernández-Bertolín, Joaquim Mullol, Mireya Fuentes-Prado, Isam Alobid, Jordi Roca-Ferrer, César Picado, Laura Pujols

     
  • ·Coding-region alterations in BTK do not universally cause X-linked agammaglobulinemia

    Página :1246-1248

    Jordan K. Abbott, Hans D. Ochs, Erwin W. Gelfand

    
  • ·Is intralymphatic immunotherapy ready for clinical use in patients with grass pollen allergy?

    Página :1248

    Marianne Witten, Hans-Jørgen Malling, Lars Blom, Britta C. Poulsen, Lars K. Poulsen

     
  • ·Epicutaneous application of house dust mite induces thymic stromal lymphopoietin in nonlesional skin of patients with atopic dermatitis

    Página :1252-1254

    Janneke Landheer, Barbara Giovannone, Jeanine D. Mattson, Sandra Tjabringa, Carla A.F.M. Bruijnzeel-Koomen, Terrill McClanahan, Rene de Waal Malefyt, Edward Knol, DirkJan Hijnen

     

• Correspondence

  • ·Uncorrected nitric oxide levels in mild asthmatics produce flawed interpretation

    Página :1255

    Brian Lipworth

    
  • ·Usefulness of alveolar nitric oxide measurement in asthma: Still debated

    Página :1255-1256

    Bruno Mahut, Christophe Delclaux

    
  • ·Reply

    Página :1256

    Nicola Scichilone, Salvatore Battaglia, Vincenzo Bellia

    
  • ·Induction of severe systemic lupus erythematosus by TNF blockade and response to an anti-IL-6 strategy: Role of IL-17?

    Página :1257

    Jae Il Shin

    
  • ·Reply

    Página :1257

    Peter M. Villiger

    
  • ·Unlocking the resistance to wheat lipid transfer protein

    Página :1257-1258

    Pedro Manuel Gamboa, Carlos Gonzalez, Catia Pereira, Manuela Catarino, Eduardo García-Lirio, Ana Soriano, Luis Fernandez Pacios, Araceli Díaz-Perales

    
  • ·Reply

    Página :1258-1259

    Paul J. Turner, Dianne E. Campbell

    

• Corrections

  • ·Correction

    Página :1259

    
  • ·Correction

    Página :1259

    
  • ·Correction

    Página :1259