Índice

• • ·Cover 1

    Página :OFC

    
• • ·Brief Overview of This Month's JACI

    Página :3A

    
• • ·Table of Contents

    Página :6A

    
• • ·Editorial Board

    Página :21A

    

• Reader services

  • ·Information for Readers

    Página :26A

    
  • ·News & Notes

    Página :30A

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  • ·CME Activities Calendar

    Página :35A

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• News beyond our pages

  • ·News Beyond Our Pages

    Página :437-438

    Marc E. Rothenberg, Jean Bousquet

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• Reviews and feature articles

  • ·What effect does asthma treatment have on airway remodeling? Current perspectives

    Página :439-448

    Sheharyar R. Durrani, Ravi K. Viswanathan, William W. Busse

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  • ·What effect does asthma treatment have on airway remodeling? Current perspectives

    Página :449-450

    
  • ·Remodeling in asthma

    Página :451-462

    Saleh Al-Muhsen, Jill R. Johnson, Qutayba Hamid

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  • ·Remodeling in asthma

    Página :463-464

    
  • ·Maintenance of certification and maintenance of professionalism

    Página :465-466

    Stephen I. Wasserman

    
  • ·Lung imaging in asthmatic patients: The picture is clearer

    Página :467-478

    Mario Castro, Sean B. Fain, Eric A. Hoffman, David S. Gierada, Serpil C. Erzurum, Sally Wenzel, National Heart, Lung, and Blood Institute’s Severe Asthma Research Program

    Resumen Resumen Esquema Esquema  
  • ·Evidence of a genetic contribution to lung function decline in asthma

    Página :479-484

    Gerard H. Koppelman, Ian Sayers

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  • ·Advancing asthma care: The glass is only half full!

    Página :485-494

    Stanley J. Szefler

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  • ·Pathophysiology of asthma: What has our current understanding taught us about new therapeutic approaches?

    Página :495-505

    Stephen T. Holgate

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• The Editors' choice

  • ·The Editors’ Choice

    Página :506-507

    Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI

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• Asthma and lower airway disease

  • ·Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation

    Página :508

    Anne E. Dixon, Richard E. Pratley, Patrick M. Forgione, David A. Kaminsky, Laurie A. Whittaker-Leclair, Laurianne A. Griffes, Jayanthi Garudathri, Danielle Raymond, Mathew E. Poynter, Janice Y. Bunn, Charles G. Irvin

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  • ·Problem solving to improve adherence and asthma outcomes in urban adults with moderate or severe asthma: A randomized controlled trial

    Página :516

    Andrea J. Apter, Xingmei Wang, Daniel K. Bogen, Cynthia S. Rand, Sean McElligott, Daniel Polsky, Rodalyn Gonzalez, Chantel Priolo, Bariituu Adam, Sabrina Geer, Thomas Ten Have

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  • ·IFNG genotype and sex interact to influence the risk of childhood asthma

    Página :524-531

    Dagan A. Loisel, Zheng Tan, Christopher J. Tisler, Michael D. Evans, Ronald E. Gangnon, Daniel J. Jackson, James E. Gern, Robert F. Lemanske, Carole Ober

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  • ·Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthma

    Página :532

    Theresa W. Guilbert, Anne Marie Singh, Zoran Danov, Michael D. Evans, Daniel J. Jackson, Ryan Burton, Kathy A. Roberg, Elizabeth L. Anderson, Tressa E. Pappas, Ronald Gangnon, James E. Gern, Robert F. Lemanske

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  • ·Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress

    Página :539-548

    Kathy T. Schroer, Aaron M. Gibson, Umasundari Sivaprasad, Stacey A. Bass, Mark B. Ericksen, Marsha Wills-Karp, Tim LeCras, Anne M. Fitzpatrick, Lou Ann S. Brown, Keith F. Stringer, Gurjit K. Khurana Hershey

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  • ·Defective epithelial barrier function in asthma

    Página :549

    Chang Xiao, Sarah M. Puddicombe, Sarah Field, Joel Haywood, Victoria Broughton-Head, Ilaria Puxeddu, Hans Michael Haitchi, Elizabeth Vernon-Wilson, David Sammut, Nicole Bedke, Catherine Cremin, Jody Sones, Ratko Djukanović, Peter H. Howarth, Jane E. Collins, Stephen T. Holgate, Phillip Monk, Donna E. Davies

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  • ·Defective function at the epithelial junction: A novel therapeutic frontier in asthma?

    Página :557-558

    Darryl A. Knight, Stephen M. Stick, Tillie-Louise Hackett

    

• Rhinitis, sinusitis, and upper airway disease

  • ·Sustained 3-year efficacy of pre- and coseasonal 5-grass-pollen sublingual immunotherapy tablets in patients with grass pollen–induced rhinoconjunctivitis

    Página :559-566

    Alain Didier, Margitta Worm, Friedrich Horak, Gordon Sussman, Olivier de Beaumont, Martine Le Gall, Michel Melac, Hans-Jorgen Malling

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• Atopic dermatitis and skin disease

  • ·A randomized, placebo-controlled, dose-ranging study of single-dose omalizumab in patients with H₁-antihistamine–refractory chronic idiopathic urticaria

    Página :567

    Sarbjit Saini, Karin E. Rosen, Hsin-Ju Hsieh, Dennis A. Wong, Edward Conner, Allen Kaplan, Sheldon Spector, Marcus Maurer

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  • ·Lesional dendritic cells in patients with chronic atopic dermatitis and psoriasis exhibit parallel ability to activate T-cell subsets

    Página :574

    Hideki Fujita, Avner Shemer, Mayte Suárez-Fariñas, Leanne M. Johnson-Huang, Suzanne Tintle, Irma Cardinale, Judilyn Fuentes-Duculan, Inna Novitskaya, John A. Carucci, James G. Krueger, Emma Guttman-Yassky

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  • ·Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response

    Página :583

    Suzanne Tintle, Avner Shemer, Mayte Suárez-Fariñas, Hideki Fujita, Patricia Gilleaudeau, Mary Sullivan-Whalen, Leanne Johnson-Huang, Andrea Chiricozzi, Irma Cardinale, Shenghui Duan, Anne Bowcock, James G. Krueger, Emma Guttman-Yassky

    Resumen Resumen Esquema Esquema   

• Food, drug, insect sting allergy, and anaphylaxis

  • ·A population-based epidemiologic study of emergency department visits for anaphylaxis in Florida

    Página :594

    Laurel Harduar-Morano, Michael R. Simon, Sharon Watkins, Carina Blackmore

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• Immune deficiencies, infection, and systemic immune disorders

  • ·Toll-like receptor 9, transmembrane activator and calcium-modulating cyclophilin ligand interactor, and CD40 synergize in causing B-cell activation

    Página :601

    Esra Ozcan, Ingrid Rauter, Lilit Garibyan, Stacey R. Dillon, Raif S. Geha

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  • ·NEMO is a key component of NF-κB– and IRF-3–dependent TLR3-mediated immunity to herpes simplex virus

    Página :610

    Magali Audry, Michael Ciancanelli, Kun Yang, Aurelie Cobat, Huey-Hsuan Chang, Vanessa Sancho-Shimizu, Lazaro Lorenzo, Tim Niehues, Janine Reichenbach, Xiao-Xia Li, Alain Israel, Laurent Abel, Jean-Laurent Casanova, Shen-Ying Zhang, Emmanuelle Jouanguy, Anne Puel

    Resumen Resumen Esquema Esquema  

• Mechanisms of allergy and clinical immunology

  • ·Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes

    Página :618

    Stephanie Brand, René Teich, Tanja Dicke, Hani Harb, Ali Ö. Yildirim, Jörg Tost, Regine Schneider-Stock, Robert A. Waterland, Uta-Maria Bauer, Erika von Mutius, Holger Garn, Petra I. Pfefferle, Harald Renz

    Resumen Resumen Esquema Esquema  
  • ·Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)–mediated mechanism

    Página :626

    MinChao Li, Qi Li, Gang Yang, Victor P. Kolosov, Juliy M. Perelman, Xiang Dong Zhou

    Resumen Resumen Esquema Esquema  
  • ·IκB kinase–driven nuclear factor-κB activation in patients with asthma and chronic obstructive pulmonary disease

    Página :635

    Rosalia Gagliardo, Pascal Chanez, Mirella Profita, Anna Bonanno, Giusy Daniela Albano, Angela Marina Montalbano, Flora Pompeo, Cesare Gagliardo, Anna Maria Merendino, Mark Gjomarkaj

    Resumen Resumen Esquema Esquema  
  • ·Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age

    Página :646

    Hans Bisgaard, Nan Li, Klaus Bonnelykke, Bo Lund Krogsgaard Chawes, Thomas Skov, Georg Paludan-Müller, Jakob Stokholm, Birgitte Smith, Karen Angeliki Krogfelt

    Resumen Resumen Esquema Esquema  
  • ·Critical role of IL-21 in modulating T_H17 and regulatory T cells in Behçet disease

    Página :655-664

    Guillaume Geri, Benjamin Terrier, Michelle Rosenzwajg, Bertrand Wechsler, Maxime Touzot, Danielle Seilhean, Tu-Anh Tran, Bahram Bodaghi, Lucile Musset, Vassili Soumelis, David Klatzmann, Patrice Cacoub, David Saadoun

    Resumen Resumen Esquema Esquema  
  • ·Intestinal microbial diversity in infancy and allergy risk at school age

    Página :653-654

    Markus Johannes Ege

    
  • ·Regulation of T_H17 and regulatory T cells in patients with Behçet disease

    Página :665-666

    Haner Direskeneli, Hiroyuki Fujita, Cezmi A. Akdis

    

• Letters to the Editor

  • ·Association of childhood allergic asthma with markers flanking the IL33 gene in Italian families

    Página :667-668

    Francesca Belpinati, Giovanni Malerba, Elisabetta Trabetti, Roberta Galavotti, Luciano Xumerle, Lydia Pescollderungg, Attilio Loris Boner, Pier Franco Pignatti

    
  • ·Depression, anxiety, and dermatologic quality of life in adolescents with atopic dermatitis

    Página :668

    Marcia J. Slattery, Marilyn J. Essex, Elliott M. Paletz, Erin R. Vanness, Mauricio Infante, Gregory M. Rogers, James E. Gern

     
  • ·Low sensitivity of commercially available rApi m 1 for diagnosis of honeybee venom allergy

    Página :671-673

    Peter Korošec, Rudolf Valenta, Irene Mittermann, Nina Čelesnik, Renato Eržen, Mihaela Zidarn, Mitja Košnik

     
  • ·IgE to Gly m 5 and Gly m 6 is associated with severe allergic reactions to soybean in Japanese children

    Página :673-675

    Komei Ito, Sigrid Sjölander, Sakura Sato, Robert Movérare, Akira Tanaka, Lars Söderström, Magnus Borres, Maryam Poorafshar, Motohiro Ebisawa

     
  • ·TNF-⍺ blockade in chronic granulomatous disease–induced hyperinflammation: Patient analysis and murine model

    Página :675

    Christine Deffert, Maria L. Olleros, Yuan Huiping, François R. Herrmann, Dina Zekry, Irene Garcia, Karl-Heinz Krause, Michela G. Schäppi

     
  • ·Functional FCGR2B gene variants influence intravenous immunoglobulin response in patients with Kawasaki disease

    Página :677

    Sadeep Shrestha, Howard W. Wiener, Aaron K. Olson, Jeffrey C. Edberg, Neil E. Bowles, Hitendra Patel, Michael A. Portman

     
  • ·Characterization of drug-specific lymphocyte responses in a patient with drug-induced liver injury

    Página :680

    Sabah El-Ghaiesh, Joseph P. Sanderson, John Farrell, Sidonie N. Lavergne, Wing-Kin Syn, Munir Pirmohamed, B. Kevin Park, Dean J. Naisbitt

     
  • ·Correction

    Página :684

     
  • ·Correction

    Página :684

    

• Correspondence

  • ·Clarification concerning amoxicillin skin testing

    Página :685

    Maria Isabel Montañez, Maria Jose Torres, Ezequiel Perez-Inestrosa, Miguel Blanca

     
  • ·Reply

    Página :686

    Eric Macy

    
  • ·Redundant ability of phagocytes to kill Aspergillus species

    Página :686-687

    Joachim Roesler, Angela Rösen-Wolff

    
  • ·Reply

    Página :687-688

    Matteo Bianchi, Maria J. Niemiec, Ulrich Siler, Constantin F. Urban, Janine Reichenbach

    
  • ·Effect of partially hydrolyzed whey infant formula and prolonged breast-feeding on the risk of allergic disease in high-risk children

    Página :688-689

    Ferdinand Haschke

    
  • ·Reply

    Página :689

    David J. Hill, Adrian J. Lowe, Clifford S. Hosking, Catherine M. Bennett, Katrina J. Allen, Christine Axelrad, John B. Carlin, Michael J. Abramson, Shyamali C. Dharmage

    

• Maintenance of Certification clinical management series

  • ·Evaluation of the child with recurrent wheezing

    Página :690

    Leonard B. Bacharier

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