Índice

• • ·Catching up on medical device safety

    Página :1

     
• • ·CD19-directed CAR T cells gain traction

    Página :2-3

    Stephen J Schuster

     
• • ·Ibrutinib: searching for a partner drug

    Página :3-5

    Arnon P Kater, Jennifer R Brown

     
• • ·Lenalidomide as maintenance for every newly diagnosed patient with multiple myeloma

    Página :5-6

    María-Victoria Mateos, Verónica González de la Calle

     
• • ·The importance of surgery in colorectal cancer treatment

    Página :6-7

    Eva Angenete

     
• • ·Competing risks of extended adjuvant aromatase inhibitors

    Página :8-9

    Eitan Amir

     
• • ·Exclusive MRI-targeted biopsy: not so fast

    Página :9-10

    Rajiv Jayadevan, Leonard S Marks

     
• • ·Drug development for glioma: are we repeating the same mistakes?

    Página :10-12

    Roger Stupp

     
• • ·Metastatic osteosarcoma challenged by regorafenib

    Página :12-14

    Dominique Heymann

     
• • ·Anti-angiogenic therapy for malignant solitary fibrous tumour: validation through collaboration

    Página :14-15

    Richard F Riedel

     
• • ·New directions in penile cancer

    Página :16-17

    Peter A S Johnstone, Philippe E Spiess, Anna R Giuliano

     
• • ·Radiosurgery and risk of intracranial malignancies: more research needed

    Página :17-18

    Alejandro Berlin, David Hodgson, Laura A Dawson

     
• • ·Patient-reported outcome monitoring in a routine paediatric oncology setting: challenges and opportunities

    Página :19-20

    Geetinder Kaur, Derek Kyte, Bryce B Reeve, Ethan Basch, Melanie Calvert

     
• • ·Increasing access to next-generation sequencing in oncology for Brazil

    Página :20-23

    Marcos Santos, Renata A Coudry, Carlos Gil Ferreira, Stephen Stefani, Isabela Werneck Cunha, Mariano Gustavo Zalis, Luiz H Araujo

     
• • ·Intraoperative lymph-node assessment during NSCLC surgery: the need for standardisation and quality evaluation

    Página :23-25

    Pascal-Alexandre Thomas

     
• • ·A gap analysis of opportunities and priorities for breast surgical research

    Página :e1

    Oreste D Gentilini, Jana De Boniface, Jean-Marc Classe, Florentia Peintinger, Toralf Reimer, Roland Reitsamer, Isabel Rubio, Marjolein Smidt, Thorsten Kuehn

    
• • ·Digitally enabled patient-reported outcome measures in cancer care

    Página :e2

    Oana C Lindner, Galina Velikova, Dan P Stark

    
• • ·Digitally enabled patient-reported outcome measures in cancer care – Authors’ reply

    Página :e3

    Lauren C Heathcote, Daniel S Goldberg, Christopher Eccleston, Sheri L Spunt, Laura E Simons, Louise Sharpe, Brian D Earp

    
• • ·Does end-of-treatment FDG-PET improve outcomes in follicular lymphoma?

    Página :e4

    Hugo J A Adams, Thomas C Kwee

    
• • ·Does end-of-treatment FDG-PET improve outcomes in follicular lymphoma? – Authors’ reply

    Página :e5

    Judith Trotman, Sally F Barrington, Michel Meignan, PET investigators from the GALLIUM study

    
• • ·One-view breast tomosynthesis vs two-view mammography: a methodological issue

    Página :e6

    Xiang Fang, Weili Kong, Jianqing Qiu, Zeping Yu, Hong Duan

    
• • ·One-view breast tomosynthesis vs two-view mammography: a methodological issue – Authors’ reply

    Página :e7

    Sophia Zackrisson, Kristina Lång, Aldana Rosso, Kristin Johnson, Magnus Dustler, Daniel Förnvik, Hannie Förnvik, Hanna Sartor, Pontus Timberg, Anders Tingberg, Ingvar Andersson

    
• • ·Trifluridine/tipiracil in metastatic gastric cancer

    Página :e8

    Zachary R McCaw, Dae Hyun Kim, Lu Tian, Haoda Fu, Lee-Jen Wei

    
• • ·Correction to Lancet Oncol 2017; 18: 672–81

    Página :e9

    
• • ·Correction to Lancet Oncol 2018; 19: 1493–503

    Página :e9

    
• • ·Correction to Lancet Oncol 2018; 19: 1569–78

    Página :e10

    
• • ·Correction to Lancet Oncol 2018; 19: 1590–601

    Página :e10

    
• • ·Correction to Lancet Oncol 2018; 19: 1654–67

    Página :e10

    
• • ·Correction to Lancet Oncol 2018; 19: 1680–87

    Página :e10

    
• • ·Correction to Lancet Oncol 2019; 20: 43–56

    Página :e10

    
• • ·Correction to Lancet Oncol 2019; 20: 88–99

    Página :e10

    
• • ·2018 American Society of Hematology Annual Meeting

    Página :26

    Katherine Gourd

    Esquema Esquema  
• • ·Derazantinib for intrahepatic cholangiocarcinoma

    Página :e11

    Elizabeth Gourd

     
• • ·Pregabalin alleviates radiotherapy-related neuropathic pain

    Página :e12

    Elizabeth Gourd

     
• • ·T-DM1 for residual, invasive, HER2-positive breast cancer

    Página :e13

    Talha Khan Burki

     
• • ·Probiotics for chemoradiotherapy-induced oral mucositis

    Página :e14

    Manjulika Das

     
• • ·Oncology meets Art: a way to understand patients’ symptoms

    Página :27

    Florian Bernard, Philippe Menei

     
• • ·Patients’ crowdfunding campaigns for alternative cancer treatments

    Página :28-29

    Jeremy Snyder, Timothy Caulfield

     
• • ·Dying to survive and cancer care in China

    Página :30

    Catherine Lucas

    
• • ·Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial

    Página :31-42

    Frederick L Locke, Armin Ghobadi, Caron A Jacobson, David B Miklos, Lazaros J Lekakis, Olalekan O Oluwole, Yi Lin, Ira Braunschweig, Brian T Hill, John M Timmerman, Abhinav Deol, Patrick M Reagan, Patrick Stiff, Ian W Flinn, Umar Farooq, Andre Goy, Peter A McSweeney, Javier Munoz, Tanya Siddiqi, Julio C Chavez, Alex F Herrera, Nancy L Bartlett, Jeffrey S Wiezorek, Lynn Navale, Allen Xue, Yizhou Jiang, Adrian Bot, John M Rossi, Jenny J Kim, William Y Go, Sattva S Neelapu

    Resumen Resumen Esquema Esquema   
• • ·Ibrutinib plus obinutuzumab versus chlorambucil plus obinutuzumab in first-line treatment of chronic lymphocytic leukaemia (iLLUMINATE): a multicentre, randomised, open-label, phase 3 trial

    Página :43-56

    Carol Moreno, Richard Greil, Fatih Demirkan, Alessandra Tedeschi, Bertrand Anz, Loree Larratt, Martin Simkovic, Olga Samoilova, Jan Novak, Dina Ben-Yehuda, Vladimir Strugov, Devinder Gill, John G Gribben, Emily Hsu, Chih-Jian Lih, Cathy Zhou, Fong Clow, Danelle F James, Lori Styles, Ian W Flinn

    Resumen Resumen Esquema Esquema   
• • ·Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial

    Página :57-73

    Graham H Jackson, Faith E Davies, Charlotte Pawlyn, David A Cairns, Alina Striha, Corinne Collett, Anna Hockaday, John R Jones, Bhuvan Kishore, Mamta Garg, Cathy D Williams, Kamaraj Karunanithi, Jindriska Lindsay, Matthew W Jenner, Gordon Cook, Nigel H Russell, Martin F Kaiser, Mark T Drayson, Roger G Owen, Walter M Gregory, Gareth J Morgan, UK NCRI Haemato-oncology Clinical Studies Group

    Resumen Resumen Esquema Esquema   
• • ·Surgical treatment and survival from colorectal cancer in Denmark, England, Norway, and Sweden: a population-based study

    Página :74-87

    Sara Benitez Majano, Chiara Di Girolamo, Bernard Rachet, Camille Maringe, Marianne Grønlie Guren, Bengt Glimelius, Lene Hjerrild Iversen, Edrun Andrea Schnell, Kristina Lundqvist, Jane Christensen, Melanie Morris, Michel P Coleman, Sarah Walters

    Resumen Resumen Esquema Esquema   
• • ·Use of letrozole after aromatase inhibitor-based therapy in postmenopausal breast cancer (NRG Oncology/NSABP B-42): a randomised, double-blind, placebo-controlled, phase 3 trial

    Página :88-99

    Eleftherios P Mamounas, Hanna Bandos, Barry C Lembersky, Jong-Hyeon Jeong, Charles E Geyer, Priya Rastogi, Louis Fehrenbacher, Mark L Graham, Stephen K Chia, Adam M Brufsky, Janice M Walshe, Gamini S Soori, Shaker R Dakhil, Thomas E Seay, James L Wade, Edward C McCarron, Soonmyung Paik, Sandra M Swain, D Lawrence Wickerham, Norman Wolmark

    Resumen Resumen Esquema Esquema   
• • ·Use of prostate systematic and targeted biopsy on the basis of multiparametric MRI in biopsy-naive patients (MRI-FIRST): a prospective, multicentre, paired diagnostic study

    Página :100-109

    Olivier Rouvière, Philippe Puech, Raphaële Renard-Penna, Michel Claudon, Catherine Roy, Florence Mège-Lechevallier, Myriam Decaussin-Petrucci, Marine Dubreuil-Chambardel, Laurent Magaud, Laurent Remontet, Alain Ruffion, Marc Colombel, Sébastien Crouzet, Anne-Marie Schott, Laurent Lemaitre, Muriel Rabilloud, Nicolas Grenier

    Resumen Resumen Esquema Esquema   
• • ·Regorafenib compared with lomustine in patients with relapsed glioblastoma (REGOMA): a multicentre, open-label, randomised, controlled, phase 2 trial

    Página :110-119

    Giuseppe Lombardi, Gian Luca De Salvo, Alba Ariela Brandes, Marica Eoli, Roberta Rudà, Marina Faedi, Ivan Lolli, Andrea Pace, Bruno Daniele, Francesco Pasqualetti, Simona Rizzato, Luisa Bellu, Ardi Pambuku, Miriam Farina, Giovanna Magni, Stefano Indraccolo, Marina Paola Gardiman, Riccardo Soffietti, Vittorina Zagonel

    Resumen Resumen Esquema Esquema   
• • ·Efficacy and safety of regorafenib in adult patients with metastatic osteosarcoma: a non-comparative, randomised, double-blind, placebo-controlled, phase 2 study

    Página :120-133

    Florence Duffaud, Olivier Mir, Pascaline Boudou-Rouquette, Sophie Piperno-Neumann, Nicolas Penel, Emanuelle Bompas, Corinne Delcambre, Elsa Kalbacher, Antoine Italiano, Olivier Collard, Christine Chevreau, Esma Saada, Nicolas Isambert, Jessy Delaye, Camille Schiffler, Corinne Bouvier, Vincent Vidal, Sylvie Chabaud, Jean-Yves Blay, French Sarcoma Group

    Resumen Resumen Esquema Esquema   
• • ·Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial

    Página :134-144

    Javier Martin-Broto, Silvia Stacchiotti, Antonio Lopez-Pousa, Andres Redondo, Daniel Bernabeu, Enrique de Alava, Paolo G Casali, Antoine Italiano, Antonio Gutierrez, David S Moura, Maria Peña-Chilet, Juan Diaz-Martin, Michele Biscuola, Miguel Taron, Paola Collini, Dominique Ranchere-Vince, Xavier Garcia del Muro, Giovanni Grignani, Sarah Dumont, Javier Martinez-Trufero, Emanuela Palmerini, Nadia Hindi, Ana Sebio, Joaquin Dopazo, Angelo Paolo Dei Tos, Axel LeCesne, Jean-Yves Blay, Josefina Cruz

    Resumen Resumen Esquema Esquema   
• • ·Prevalence of human papillomavirus DNA and p16^INK4a in penile cancer and penile intraepithelial neoplasia: a systematic review and meta-analysis

    Página :145-158

    Tina Bech Olesen, Freja Lærke Sand, Christina Louise Rasmussen, Vanna Albieri, Birgitte Grønkær Toft, Bodil Norrild, Christian Munk, Susanne Krüger Kjær

    Resumen Resumen Esquema Esquema   
• • ·Risk of radiation-associated intracranial malignancy after stereotactic radiosurgery: a retrospective, multicentre, cohort study

    Página :159-164

    Amparo Wolf, Kyla Naylor, Moses Tam, Akram Habibi, Josef Novotny, Roman Liš?ák, Nuria Martinez-Moreno, Roberto Martinez-Alvarez, Nathaniel Sisterson, John G Golfinos, Joshua Silverman, Hideyuki Kano, Jason Sheehan, L Dade Lunsford, Douglas Kondziolka

    Resumen Resumen Esquema Esquema  
• • ·Exploring and comparing adverse events between PARP inhibitors

    Página :e15

    Christopher J LaFargue, Graziela Z Dal Molin, Anil K Sood, Robert L Coleman

    Resumen Resumen Esquema Esquema  
• • ·Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium

    Página :e29

    Eva Clemens, Marry M van den Heuvel-Eibrink, Renée L Mulder, Leontien C M Kremer, Melissa M Hudson, Roderick Skinner, Louis S Constine, Johnnie K Bass, Claudia E Kuehni, Thorsten Langer, Elvira C van Dalen, Edith Bardi, Nicolas-Xavier Bonne, Penelope R Brock, Beth Brooks, Bruce Carleton, Eric Caron, Kay W Chang, Karen Johnston, Kristin Knight, Paul C Nathan, Etan Orgel, Pinki K Prasad, Jan Rottenberg, Katrin Scheinemann, Andrica C H de Vries, Thomas Walwyn, Annette Weiss, Antoinette am Zehnhoff-Dinnesen, Richard J Cohn, Wendy Landier, International Guideline Harmonization Group ototoxicity group ‡

    Resumen Resumen Esquema Esquema   
• • ·Childhood cancer burden: a review of global estimates

    Página :e42

    Nickhill Bhakta, Lisa M Force, Claudia Allemani, Rifat Atun, Freddie Bray, Michel P Coleman, Eva Steliarova-Foucher, A Lindsay Frazier, Leslie L Robison, Carlos Rodriguez-Galindo, Christina Fitzmaurice

    Resumen Resumen Esquema Esquema   
• • ·New therapeutic perspectives to manage refractory immune checkpoint-related toxicities

    Página :e54

    Filipe Martins, Gerasimos P Sykiotis, Michel Maillard, Montserrat Fraga, Camillo Ribi, Thierry Kuntzer, Olivier Michielin, Solange Peters, Georges Coukos, Francois Spertini, John A Thompson, Michel Obeid

    Resumen Resumen Esquema Esquema  
• • ·Tyrosine kinase inhibitor-induced corneal ulcers

    Página :e65

    Ka Wai Kam, Posey Po Yin Wong, Alvin L Young