The interplay between the intestinal microbiota and the immune system - 05/02/15
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Summary |
The relationship between commensal microbes and their hosts has been studied for many years. Commensal microorganisms are known to have a significant role in regulating the physiology of their hosts and preventing pathogenic infections while the hosts’ immune system is important in determining the composition of the microbiota. More recently, specific effects of the intestinal microbiota on the local and distal immune systems have been uncovered with important consequences for health and disease, and alterations in intestinal microbial composition has been associated with various disease states. Here, we will review the current understanding of the microbiota/immune system crosstalk, highlight the clinical consequences of changes in the microbiota and consider how to harness this symbiotic relationship to improve public health.
El texto completo de este artículo está disponible en PDF.Abbreviations : AhR, AMP, APRIL, BAFF, DC, EAE, GALT, GvHD, HDAC, IBD, IEC, ILC, ILF, iTreg, mLN, MNP, NOD, PP, PSA, SCFA, sIgA, SLO
Esquema
Vol 39 - N° 1
P. 9-19 - février 2015 Regresar al número
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Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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