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Handgrip Strength Predicts Persistent Walking Recovery After Hip Fracture Surgery - 19/11/13

Doi : 10.1016/j.amjmed.2013.04.017 
Elisabetta Savino, MD a, Emilio Martini, MD b, Fulvio Lauretani, MD c, Giulio Pioli, MD, PhD d, Anna Maria Zagatti, MD e, Carlo Frondini, MD b, Francesca Pellicciotti, MD d, Antonio Giordano, MD c, Alberto Ferrari, MD d, Anna Nardelli, MD c, Maria Luisa Davoli, MD d, Amedeo Zurlo, MD e, Maria Lia Lunardelli, MD b, Stefano Volpato, MD, MPH a,
a Department of Medical Sciences, University of Ferrara, Ferrara, Italy 
b Orthogeriatric Unit, Department of Internal Medicine, Ageing and Nephrology, University Hospital Policlinico S. Orsola Malpighi, Bologna, Italy 
c Geriatric Unit, Geriatric-Rehabilitation Department, University Hospital of Parma, Parma, Italy 
d Geriatric Unit, Department of Neuromotor Physiology, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy 
e Orthogeriatric Unit, S. Anna Hospital, Ferrara, Italy 

Requests for reprints should be addressed to Stefano Volpato, MD, MPH, Department of Medical Sciences, University of Ferrara, Via Savonarola, 9, I-44100 Ferrara, Italy.

Michael W. Rich, MD, Section Editor

Abstract

Background

In older people, hip fractures often lead to disability and death. We evaluated handgrip strength, an objective measure of physical function for bedridden patients, as a predictor of walking recovery in the year after fracture surgery.

Methods

This multicenter prospective cohort study included 504 patients, aged 70 years or more, who were admitted to the hospital for hip fracture surgery and were formerly able to walk independently. A multidimensional geriatric evaluation that included a physical examination, Short Portable Mental Status Questionnaire, Geriatric Depression Scale, Charlson Index, Basic Activities of Daily Living, and grip strength was administered at the time of admission. Follow-ups were performed every 3 months for 1 year after surgery to assess functional status and survival. The walking recovery probability was evaluated using multivariable logistic regression models.

Results

The mean age of the participants was 85.3 ± 5.5 years, and 76.1% of the participants were women. The mean grip strength was greater in men (β: 6.6 ± 0.62, P < .001) and was directly related to the Short Portable Mental Status Questionnaire results (P < .001), Basic Activities of Daily Living results (P < .001), serum vitamin D levels (P = .03), and time before surgery (P < .001), whereas it was inversely related to age (P < .001), Geriatric Depression Scale score (P < .001), and Charlson Index (P < .001). After adjusting for confounders, the grip strength was directly associated with the probability of both incident and persistent walking recovery (odds ratio highest tertile vs lowest tertile, 2.84, confidence interval, 1.76-4.59 and 2.79, confidence interval, 1.35-5.79, respectively).

Conclusions

In older patients with hip fractures, early grip strength evaluation might provide important prognostic information regarding the patient's future functional trajectory.

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Keywords : Grip strength, Hip fracture, Walking recovery


Esquema


 Funding: The study was funded by the Emilia Romagna Region (Region-University Research Program 2007-2009): Grant PRUa2-2007-004.
 Conflict of Interest: None.
 Authorship: All authors had access to the data and played a role in writing this manuscript.


© 2013  Elsevier Inc. Reservados todos los derechos.
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Vol 126 - N° 12

P. 1068 - décembre 2013 Regresar al número
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