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Alternative Smoking Cessation Aids: A Meta-analysis of Randomized Controlled Trials - 22/05/12

Doi : 10.1016/j.amjmed.2011.09.028 
Mehdi Tahiri, MD a, b, c, Salvatore Mottillo, MD a, b, c, Lawrence Joseph, PhD d, e, Louise Pilote, MD, MPH, PhD d, e, f, Mark J. Eisenberg, MD, MPH a, c, d,
a Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital/McGill University, Montreal, Quebec, Canada 
b Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada 
c Lady Davis Institute for Medical Research, Jewish General Hospital/McGill University, Montreal, Quebec, Canada 
d Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada 
e Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada 
f Division of Internal Medicine, McGill University Health Centre, Montreal, Quebec, Canada 

Reprint requests should be addressed to: Mark J. Eisenberg, MD, MPH, Professor of Medicine, Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital/McGill University, 3755 Côte Ste-Catherine Road, Suite H-421.1, Montreal, Quebec, Canada H3T 1E2

Abstract

Background

Acupuncture, hypnotherapy, and aversive smoking are the most frequently studied alternative smoking cessation aids. These aids are often used as alternatives to pharmacotherapies for smoking cessation; however, their efficacy is unclear.

Methods

We carried out a random effect meta-analysis of randomized controlled trials to determine the efficacy of alternative smoking cessation aids. We systematically searched the Cochrane Library, EMBASE, Medline, and PsycINFO databases through December 2010. We only included trials that reported cessation outcomes as point prevalence or continuous abstinence at 6 or 12 months.

Results

Fourteen trials were identified; 6 investigated acupuncture (823 patients); 4 investigated hypnotherapy (273 patients); and 4 investigated aversive smoking (99 patients). The estimated mean treatment effects were acupuncture (odds ratio [OR], 3.53; 95% confidence interval [CI], 1.03-12.07), hypnotherapy (OR, 4.55; 95% CI, 0.98-21.01), and aversive smoking (OR, 4.26; 95% CI, 1.26-14.38).

Conclusion

Our results suggest that acupuncture and hypnotherapy may help smokers quit. Aversive smoking also may help smokers quit; however, there are no recent trials investigating this intervention. More evidence is needed to determine whether alternative interventions are as efficacious as pharmacotherapies.

El texto completo de este artículo está disponible en PDF.

Keywords : Acupuncture, Alternative smoking cessation aid, Aversive smoking, Hypnotherapy, Meta-analysis, Smoking cessation


Esquema


 Funding: MT was supported by a Canadian Cardiovascular Outcomes Research Team summer studentship funded through a Canadian Institutes of Health Research Team Grant in Cardiovascular Outcomes Research. LJ is a Chercheur-National of the Fonds de la Recherche en Santé du Québec (FRSQ). LP is a Chercheur-National of the FRSQ. MJE is a Chercheur-National of the FRSQ.
 Conflict of Interest: None.
 Authorship: All authors had access to the data and played a role in writing this manuscript.


© 2012  Elsevier Inc. Reservados todos los derechos.
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Vol 125 - N° 6

P. 576-584 - juin 2012 Regresar al número
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