Awareness of the problem of false electrocardiographic diagnosis of septal infarction due to cranially misplaced precordial leads V1 and V2, a common technical error, is important because this pseudo-pathologic finding can trigger unnecessary medical procedures and have other adverse sequelae. The non-trivial nature of this problem is emphasized by the case of a patient in whom the misdiagnosis caused loss of an employment opportunity. We demonstrate how P wave morphology in lead V2 can aid the clinician in suspecting erroneous right precordial lead placement in cases of apparent septal infarction. Ultimately, improved education of health care personnel regarding accurate precordial lead positioning technique is needed to minimize the occurrence of this electrocardiographic misdiagnosis.