Gender Differences in Office and Ambulatory Control of Hypertension - 20/08/11
, Julián Segura, MD b, Alejandro de la Sierra, MD c, Manuel Gorostidi, MD d, Fernando Rodríguez-Artalejo, MD a, Javier Sobrino, MD e, Juan J. de la Cruz, BS a, Ernest Vinyoles, MD f, Raquel Hernández del Rey, MD g, Auxiliadora Graciani, MD a, Luis M. Ruilope, MD bSpanish Society of Hypertension ABPM Registry Investigators
Requests for reprints should be addressed to José R Banegas, MD, Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid, Avda Arzobispo Morcillo, 2. 28029 Madrid, SpainAbstract |
Background |
Gender differences in hypertension control have not been explored fully.
Methods |
We studied 15,212 white men and 13,936 white women with treated hypertension who were drawn from the Spanish Ambulatory Blood Pressure Registry. For each participant, we obtained office blood pressure (BP) (average of 2 readings) and 24-hour ambulatory BP (average of measurements performed every 20 minutes during day and night).
Results |
Only 16.4% of women and 14.7% of men had both office (<140/90 mm Hg) and ambulatory (<130/80 mm Hg) BP controlled (P<.001). Women had a lower frequency of masked hypertension (office BP<140/90 mm Hg and ambulatory BP≥130/80 mm Hg) than men (5.9% vs 7.9%, P<.001). Women had a higher frequency of isolated office hypertension (office BP≥140/90 mm Hg and ambulatory BP<130/80 mm Hg) (32.5% vs 24.2%, P<.001). Although office BP control (office BP<140/90 mm Hg, regardless of ambulatory values) was similar in women and men (22.3% vs 22.6%, P=.542), ambulatory BP control (ambulatory BP<130/80 mm Hg, regardless of office values) was higher in women than in men (48.9% vs 38.9%, P<.001). After adjustment for age, number of antihypertensive drugs, hypertension duration, and risk factors, gender differences in BP control remained practically unchanged.
Conclusion |
Ambulatory BP control was higher in women than in men. This may be due to the higher frequency of isolated office hypertension in women, and it is not explained by gender differences in other important clinical characteristics.
El texto completo de este artículo está disponible en PDF.Keywords : Ambulatory blood pressure, Control, Office blood pressure, Sex, Treatment goals
Esquema
| Funding: The main funding for the study was obtained from Lacer Spain, S.A. through an unrestricted educational grant. The funding body had no role in the study design, the analysis and interpretation of data, writing the report, or the decision to submit the article for publication. |
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| Conflict of interest: none. |
Vol 121 - N° 12
P. 1078-1084 - décembre 2008 Regresar al número
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