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Moderate-Intensity Exercise Reduces the Incidence of Colds Among Postmenopausal Women - 20/08/11

Doi : 10.1016/j.amjmed.2006.06.033 
Jessica Chubak, MBHL a, b, Anne McTiernan, MD, PhD a, b, c, Bess Sorensen, MS a, Mark H. Wener, MD c, d, Yutaka Yasui, PhD e, Mariebeth Velasquez f, Brent Wood, MD, PhD d, Kumar B. Rajan, MS a, g, Catherine M. Wetmore, MPH b, John D. Potter, MD, PhD a, b, Cornelia M. Ulrich, PhD a, b,
a Fred Hutchinson Cancer Research Center, Cancer Prevention Program, Seattle, Wash 
b Department of Epidemiology, University of Washington, Seattle, Wash 
c Department of Medicine, University of Washington, Seattle, Wash 
d Department of Laboratory Medicine, University of Washington, Seattle, Wash 
e University of Alberta, Department of Public Health Sciences, Edmonton, Alberta 
f University of New Mexico, Department of Psychiatry, Albuquerque, NM 
g University of Washington, Department of Biostatistics, Seattle, Wash. 

Requests for reprints should be addressed to Cornelia Ulrich, PhD, Fred Hutchinson Cancer Research Center, Cancer Prevention Program, 1100 Fairview Ave N, M4-B402, PO Box 19024, Seattle, WA 98109-1024.

Abstract

Purpose

Our aim was to assess the effect of a moderate-intensity, year-long exercise program on the risk of colds and other upper respiratory tract infections in postmenopausal women.

Subjects

A total of 115 overweight and obese, sedentary, postmenopausal women in the Seattle area participated.

Methods

Participants were randomly assigned to the moderate-intensity exercise group or the control group. The intervention consisted of 45 minutes of moderate-intensity exercise 5 days per week for 12 months. Control participants attended once-weekly, 45-minute stretching sessions. Questionnaires asking about upper respiratory tract infections in the previous 3 months were administered quarterly during the course of the year-long trial. Poisson regression was used to estimate the effect of exercise on colds and other upper respiratory tract infections.

Results

Over 12 months, the risk of colds decreased in exercisers relative to stretchers (P = .02): In the final 3 months of the study, the risk of colds in stretchers was more than threefold that of exercisers (P = .03). Risk of upper respiratory tract infections overall did not differ (P = .16), yet may have been biased by differential proportions of influenza vaccinations in the intervention and control groups.

Conclusions

This study suggests that 1 year of moderate-intensity exercise training can reduce the incidence of colds among postmenopausal women. These findings are of public health relevance and add a new facet to the growing literature on the health benefits of moderate exercise.

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Keywords : Colds, Upper respiratory tract infections, Exercise, Postmenopausal women, Prevention, Overweight


Esquema


 This study was supported by a grant from the National Cancer Institute (NCI) (R01 CA 69334). Ms. Chubak was supported by grant T32 CA09168 from the NCI. The contents of this publication are solely the responsibility of the authors and do not necessarily represent the official views of the NCI or National Institutes of Health. Dr. Wener was supported in part by the University of Washington Clinical Nutrition Research Grant (DK35816).


© 2006  Elsevier Inc. Reservados todos los derechos.
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Vol 119 - N° 11

P. 937 - novembre 2006 Regresar al número
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