Intraoperative Cell Salvage During Radical Cystectomy Does Not Affect Long-Term Survival - 09/08/11
, Murugesan Manoharan, Yulong Yang, Mark S. Soloway
Reprint requests: Alan M. Nieder, M.D., Department of Urology, University of Miami School of Medicine, 4306 Alton Road, #3014, Miami Beach, FL 33140.Resumen |
Objectives |
To evaluate the risk of long-term recurrence for patients who received cell-salvaged blood during radical cystectomy (RC).
Methods |
We retrospectively analyzed an RC database and compared those who did and did not receive cell-salvaged blood according to baseline parameters, pathologic outcomes, and recurrence.
Results |
A total of 378 patients underwent RC between 1992 and 2005 by one surgeon. Of these, 65 (17.2%) received cell-salvaged blood and 313 (82.8%) did not. The two groups had similar baseline characteristics. There were no differences between the two groups when compared by pathologic stage. The median follow-up for patients who did and did not receive cell-salvaged blood was 19.1 and 20.7 months, respectively (P = 0.464). The 3-year disease-specific survival rate for the two groups was 72.2% and 73.0%, respectively (P = 0.90).
Conclusions |
Intraoperative cell salvage is a safe blood management strategy for patients undergoing RC. There is no increased risk of metastatic disease or death for those who receive cell-salvaged blood. Concerns about spreading tumors cells by IOCS during RC would seem unwarranted. However, only a prospective, multicenter, randomized trial would provide the most valid assessment of the safety of IOCS.
El texto completo de este artículo está disponible en PDF.Esquema
Vol 69 - N° 5
P. 881-884 - mai 2007 Regresar al número
Artículo precedente
- Multicenter Prospective Randomized 52-Week Trial of Calcium Hydroxylapatite Versus Bovine Dermal Collagen for Treatment of Stress Urinary Incontinence
- R.D. Mayer, R.R. Dmochowski, R.A. Appell, P.K. Sand, I.W. Klimberg, K. Jacoby, C.W. Graham, J.A. Snyder, V.W. Nitti, J.C. Winters
- Is Nasogastric Tube Drainage Required After Reconstructive Surgery for Neurogenic Bladder Dysfunction?
- Bradley A. Erickson, Ryan P. Dorin, J. Quentin Clemens
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
¿Ya suscrito a @@106933@@ revista ?