Isolated Aerobic Exercise and Weight Loss: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - 25/07/11
Requests for reprints should be addressed to Mark J. Eisenberg, MD, MPH, Divisions of Cardiology and Clinical Epidemiology, Jewish General Hospital/McGill University, 3755 Rue Cote Ste. Catherine, Suite H-421, Montreal, QC H3T 1E2, CanadaAbstract |
Background |
Aerobic exercise is a common nonpharmacological intervention for the management of obesity. However, the efficacy of isolated aerobic exercise at promoting weight loss is unclear. We conducted a systematic review and meta-analysis to evaluate the efficacy of isolated aerobic exercise programs in overweight and obese populations.
Methods |
We searched for published randomized controlled trial reports of aerobic exercise through January 20, 2010. Trials with an isolated aerobic exercise intervention were included. A random-effect model was used to synthesize the results of each intervention.
Results |
We identified 14 trials involving 1847 patients. The duration of aerobic exercise programs ranged from 12 weeks to 12 months. Results were pooled for programs with 6-month duration and programs with 12-month duration. Six-month programs were associated with a modest reduction in weight (weighted mean difference [WMD]=−1.6 kg; 95% confidence interval [CI], −1.64 to −1.56) and waist circumference (WMD=−2.12 cm; 95% CI, −2.81 to −1.44). Twelve-month programs also were associated with modest reductions in weight (WMD=−1.7 kg; 95% CI, −2.29 to −1.11) and waist circumference (WMD=−1.95 cm; 95% CI, −3.62 to −0.29).
Conclusion |
Moderate-intensity aerobic exercise programs of 6-12 months induce a modest reduction in weight and waist circumference in overweight and obese populations. Our results show that isolated aerobic exercise is not an effective weight loss therapy in these patients. Isolated aerobic exercise provides modest benefits to blood pressure and lipid levels and may still be an effective weight loss therapy in conjunction with diets.
El texto completo de este artículo está disponible en PDF.Keywords : Abdominal obesity, Aerobic exercise, Cardiovascular risk, Meta-analysis, Obesity, Weight loss
Esquema
| Funding: This work is supported by the Canadian Institutes of Health Research (CIHR grant number is 103506). Dr. Eisenberg is a Chercheur-National of the Fonds de la Recherche en Santé du Québec (FRSQ). Dr. Joseph is a Chercheur-National of the FRSQ. Dr. Pilote is a Chercheur-National of the FRSQ. Dr. Poirier is a Senior Physician-Scientist of the FRSQ. Dr. Schiffrin holds a Canada Research Chair in Vascular and Hypertension Research. |
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| Conflict of Interest: Dr. Genest is on the speaker's bureau for Merck and Astra Zeneca. No other authors have any conflicts of interest. |
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| Authorship: All authors had access to the data and played a role in writing this manuscript. |
Vol 124 - N° 8
P. 747-755 - août 2011 Regresar al número
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