Long COVID: Clinical Findings, Pathology, and Endothelial Molecular Mechanisms - 18/12/24
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Abstract |
Persistence of COVID-19 symptoms may follow severe acute respiratory syndrome coronavirus 2 infection. The incidence of long COVID increases with the severity of acute disease, but even mild disease can be associated with sequelae. The symptoms vary widely, with fatigue, shortness of breath, and cognitive dysfunction the most common. Abnormalities of multiple organs have been documented, and histopathology has revealed widespread microthrombi. Elevated levels of complement are present in acute COVID-19 patients and may persist at lower levels in long COVID. Evidence supports complement activation, with endotheliopathy-associated disease as the molecular mechanism causing both acute and long COVID.
El texto completo de este artículo está disponible en PDF.Keywords : Complement, Endotheliopathy, Long COVID, Microthrombosis
Esquema
| Funding: There is no support of funding in the preparation and publication of this manuscript. |
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| Conflicts of Interest: HBH has neither financial nor non-financial competing interests in regards to this manuscript. |
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| Authorship: As the sole author, I alone had access to the data and writing of the manuscript. |
Vol 138 - N° 1
P. 91-97 - janvier 2025 Regresar al número
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