Recovery after admission with COVID-19 pneumonia – A follow-up study - 06/06/23
, Antine Flikweert a, 1, Arthur du Mee b, 1, Kim Gense d, Sander Talman a, Merijn Kant a, c, Ingrid De Backer a
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Abstract |
Introduction |
We performed this study to describe clinical, radiological and pulmonary function outcomes of patients with COVID-19 pneumonia 1 year after discharge from hospital.
Methods |
This is a prospective longitudinal study on patients admitted with COVID-19 pneumonia in March and April 2020. 162 patients were classified as moderate, severe or critical. Symptoms and pulmonary function were assessed at 3 months and 1 year after discharge. Chest CT scans were made during hospital admission, at 3 months and, in case of persistent radiological abnormalities, after 1 year.
Results |
54% of patients reported full recovery of their pre-illness fitness after 1 year. 53% still reported exertional dyspnoea, independent of illness severity. DLCOc < 80% after 1 year was found in 74% of critical, 50% of severe and 38% of moderate cases. For KCOc<80%, no between-group difference was found. Restriction (TLC<80%) was found in 28% of critical, 5% of severe, and 13% of moderate cases. At baseline, chest CT score was significantly higher for the critical illness group, but after 1 year, there was no significant difference. Most resolution of abnormalities occurred before 3 months. A high prevalence of fibrotic lesions (24%) and subpleural banding (27%) was found.
Conclusion/clinical implication |
A large proportion of patients experience consequences of COVID-19 pneumonia one year after discharge, irrespective of initial disease severity. Follow-up of patients admitted with COVID-19 is therefore warranted. An evaluation of symptoms, pulmonary function and radiology three months after discharge can discriminate between patients with early complete recovery and those with persistent abnormalities.
El texto completo de este artículo está disponible en PDF.Keywords : COVID-19, Pneumonia, Pulmonary function, Radiology, Dyspnoea
Esquema
Vol 83
Artículo 101001- juin 2023 Regresar al número
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